Is interleukin-18 associated with polycystic ovary syndrome?

abstract：BACKGROUND:Mammalian oocyte meiotic maturation involves a number of important processes, including spindle assembly and migration, cortical reorganization and polar body extrusion. Numerous proteins contribute to these processes, but it is unknown whether MKlp2 (mitotic kinesin-like protein 2; also called KIF20A), a mi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Liu J,Wang QC,Cui XS,Wang ZB,Kim NH,Sun SC

更新日期：2013-12-21 00:00:00

abstract：BACKGROUND:Previous caesarean scar pregnancy is one type of ectopic pregnancy in myometrium and fibrous tissue of previous caesarean scar. One of the therapeutic methods of this type of ectopic pregnancy is treatment with methotrexate. Given various findings on the treatment of caesarean scar pregnancy with methotrexat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Salari N,Kazeminia M,Shohaimi S,Nankali AA,Mohammadi M

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that progestin-primed ovarian stimulation (PPOS) protocol was a feasible and efficient method in in vitro fertilization (IVF) cycle. However, its application in women with advanced age has not been determined yet. The purpose of this study was to investigate its efficacy in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Peng Q,Cao X,Wang J,Wang L,Xu J,Ji X,Liu S,Zhu J,Dong X

更新日期：2019-11-09 00:00:00

abstract：:The aim of our research was to examine the ability of density gradient preparation BoviPure and swim up method on bull sperm separation and in vitro embryo production (IVP) systems. Frozen/thawed semen from six Simmental bulls was pooled and treated using both methods. The sperm motility, concentration, membrane activ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samardzija M,Karadjole M,Getz I,Makek Z,Cergolj M,Dobranic T

更新日期：2006-11-13 00:00:00

abstract：:During rat estrous cycle, the endometrium proliferates in response to sex steroids and specific endometrial epithelial cells undergo apoptosis in absence of embryonic factors. The central executioner of apoptosis is a family of aspartic acid-specific cysteine proteases known as caspases. Smac/DIABLO is released from t...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Leblanc V,Dery MC,Shooner C,Asselin E

更新日期：2003-08-27 00:00:00

abstract：BACKGROUND:Alpha 2 macroglobulin (A2M; also known as ovostatin), a homotetrameric protein with four disulfide-linked subunits, has the unique feature of inactivating/inhibiting most known proteases including serine-, threonine-, cysteine-, aspartic- and metalloproteases. In chickens, A2M has been identified and charact...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lim W,Jeong W,Kim JH,Lee JY,Kim J,Bazer FW,Han JY,Song G

更新日期：2011-10-07 00:00:00

abstract：BACKGROUND:It is not well established whether the increased number of leukocytes in the seminal fluid impairs the outcomes of assisted reproductive technology (ART). This investigation analysed the outcomes of the intracytoplasmic sperm injection (ICSI) and intracytoplasmic morphologically selected sperm injection (IMS...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cavagna M,Oliveira JB,Petersen CG,Mauri AL,Silva LF,Massaro FC,Baruffi RL,Franco JG Jr

更新日期：2012-06-15 00:00:00

abstract：PURPOSE:To investigate the associations between blastocyst development and the sex ratio (male:female) among singleton live births resulting from single-blastocyst frozen embryo transfer (FET) cycles. METHODS:Patients with singleton live births following the first autologous single FET of non- preimplantation genetic ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lou H,Li N,Zhang X,Sun L,Wang X,Hao D,Cui S

更新日期：2020-07-15 00:00:00

abstract：BACKGROUND:Despite significant advances in contraceptive options for women, vasectomy and condoms are the only options available for male contraception. Due to this limitation, the burden of contraception resides on the shoulders of females only. Therefore, there is an urgent need to develop a safe, effective and rever...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Chauhan A,Thaper D,Prabha V

更新日期：2020-09-30 00:00:00

abstract：BACKGROUND:Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadotropin in mammals. However, it...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Han X,He Y,Zeng G,Wang Y,Sun W,Liu J,Sun Y,Yu J

更新日期：2017-05-02 00:00:00

abstract：BACKGROUND:The Rapid-i is a new FDA cleared closed carrier for embryo vitrification. The cooling rate of - 1220°C/min is far lower than that reported with open vitrification systems such as the cryoloop (-15,000°C/min). Little published data is currently available on this device. This study presents our initial clinica...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Desai NN,Goldberg JM,Austin C,Falcone T

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:The cell membrane water channel protein, aquaporins (AQPs), regulate cellular water transport and cell volume and play a key role in water homeostasis. Recently, AQPs are considered as important players in the field of reproduction. In previous studies, we have established the presence of AQP1 and 5 in porci...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Skowronska A,Młotkowska P,Wojciechowicz B,Okrasa S,Nielsen S,Skowronski MT

更新日期：2015-02-18 00:00:00

abstract：BACKGROUND:The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise. METHODS:Authors optimize the spectrophotometric method to measure glutathione peroxidase activity in rat red blood cell membranes. RESUL...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gallo G,Martino G

更新日期：2009-01-26 00:00:00

abstract：BACKGROUND:Seminal plasma serves as a natural reservoir of antioxidants. It helps to remove excessive formation of reactive oxygen species (ROS) and consequently, reduce oxidative stress. Proteomic profiling of seminal plasma proteins is important to understand the molecular mechanisms underlying oxidative stress and s...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Sharma R,Agarwal A,Mohanty G,Du Plessis SS,Gopalan B,Willard B,Yadav SP,Sabanegh E

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:Prostaglandins are important for female reproduction. Prostaglandin-E2 acts via four different receptor subtypes, EP1, EP2, EP3 and EP4 whereas prostaglandin-F2alpha acts through FP. The functions of prostaglandins depend on the expression of their receptors in different uterine cell types. Our aim was to in...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Blesson CS,Büttner E,Masironi B,Sahlin L

更新日期：2012-01-18 00:00:00

abstract：OBJECTIVE:To assess the effectiveness and safety of omega-3 fatty acid for patients with PCOS. METHODS:In this meta-analysis, data from randomized controlled trials were obtained to assess the effects of omega-3 fatty acid versus placebo or western medicine in women with PCOS. The study's registration number is CRD420...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Yang K,Zeng L,Bao T,Ge J

更新日期：2018-03-27 00:00:00

abstract：:The corpus luteum is an endocrine gland whose limited lifespan is hormonally programmed. This debate article summarizes findings of our research group that challenge the principle that the end of function of the corpus luteum or luteal regression, once triggered, cannot be reversed. Overturning luteal regression by ph...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Telleria CM

更新日期：2006-10-30 00:00:00

abstract：BACKGROUND:To evaluate the relationship between endometrial thickness on day of human chorionic gonadotrophin administration (hCG) and pregnancy outcome in a large number of consecutive in vitro fertilization and embryo transfer (IVF-ET) cycles. METHODS:A retrospective cohort study including all patients who had IVF-E...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Al-Ghamdi A,Coskun S,Al-Hassan S,Al-Rejjal R,Awartani K

更新日期：2008-09-02 00:00:00

abstract：BACKGROUND:Di(2-ethylhexyl) phthalate (DEHP) exposure reduces embryo implantations, increases embryonic loss, and decreases fetal body weights. However, whether it is associated with the alteration of luteal function remains unknown. Thus, our aim in this study was to explore the effect and mechanism of DEHP on luteal ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo M,Lai L,Zong T,Lin Y,Yang B,Zhang L,Li M,Kuang H

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Stereology is an established method to extrapolate three-dimensional quantities from two-dimensional images. It was applied to placentation in the mouse, but not yet for other rodents. Herein, we provide the first study on quantitative placental development in a sigmodontine rodent species with relatively si...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Favaron PO,Mess AM,de Oliveira MF,Gabory A,Miglino MA,Chavatte-Palmer P,Tarrade A

更新日期：2013-02-21 00:00:00

abstract：:LINE1 retrotransposons are mobile DNA elements that copy and paste themselves into new sites in the genome. To ensure their evolutionary success, heritable new LINE-1 insertions accumulate in cells that can transmit genetic information to the next generation (i.e., germ cells and embryonic stem cells). It is our hypot...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lou C,Goodier JL,Qiang R

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:Macrophage migration inhibitory factor (MIF) has special pro-inflammatory roles, affecting the functions of macrophages and lymphocytes and counter-regulating the effects of glucocorticoids on the immune response. The conspicuous expression of MIF during human implantation and early embryonic development als...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Faria MR,Hoshida MS,Ferro EA,Ietta F,Paulesu L,Bevilacqua E

更新日期：2010-08-04 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase 2 (MMP-2) has been reported to be an important regulator of cell migration and invasion through degradation of the extracellular matrix (ECM) in many diseases, such as cancer and endometriosis. Here, we found calcium-activated neutral protease 7 (CAPN 7) expression was markedly upreg...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Liu H,Jiang Y,Jin X,Zhu L,Shen X,Zhang Q,Wang B,Wang J,Hu Y,Yan G,Sun H

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:Declining numbers of wild giant anteaters highlight the importance of sustainable captive populations. Unfortunately, captive reproductive management is limited by the lack of external physical indicators of female reproductive status and the aggressive behavior of males. We examined the endocrinology of the...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Knott KK,Roberts BM,Maly MA,Vance CK,Debeachaump J,Majors J,Riger P,Decaluwe H,Kouba AJ

更新日期：2013-08-27 00:00:00

abstract：:Fertilin alpha (ADAM-1) and beta (ADAM-2) are integral membrane proteins of the ADAM family that form a fertilin complex involved in key steps of the sperm-oocyte membrane interaction. In the present work, we analyzed the presence of ADAM-1 and ADAM-2 mRNAs, the spermatozoa proteins' processing and their sub-cellular ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fàbrega A,Guyonnet B,Dacheux JL,Gatti JL,Puigmulé M,Bonet S,Pinart E

更新日期：2011-06-30 00:00:00

abstract：BACKGROUND:L-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regulate the oxidative and metabolic status of the female reproductive system. The vulnerability of this system to free radicals demand for advanced strategies to combat them. For this purpose, the 'q...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Agarwal A,Sengupta P,Durairajanayagam D

更新日期：2018-01-26 00:00:00

abstract：BACKGROUND:Morphometric and morphokinetic evaluation of in vitro cultured human embryos allows evaluation without time restriction and reduces intra- and inter-observer variability. Even though these technologies have been reported to improve the quality of cleavage stage embryo evaluation during fresh culture, possibl...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Fernandez Gallardo E,Spiessens C,D'Hooghe T,Debrock S

更新日期：2017-10-03 00:00:00

abstract：BACKGROUND:Despite being born with a significant number of primordial cells which representing the ancestor cells of the germ-line, women experience a depletion of ovarian reserve and sub-fertility mid-way into their healthy lives. The poor ovarian response is a substantial limiting factor amplified with higher materna...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Khan HL,Bhatti S,Suhail S,Gul R,Awais A,Hamayun H,Enver F,Abbas S,Hassan Z,Nisar R,Sardar S,Asif W

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:Women with Polycystic Ovary Syndrome (PCOS) present a heterogeneous reproductive and metabolic profile with an increased lifetime risk of Type 2 Diabetes (T2D). Early biomarkers of these metabolic disturbances in PCOS women have not been identified. The abundance of circulating insulin gene promotor cell-fre...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Udesen PB,Sørensen AE,Joglekar MV,Hardikar AA,Wissing MLM,Englund AM,Dalgaard LT

更新日期：2019-04-05 00:00:00