Mammographic screening for women aged 40 to 49 years: the primary care practitioner's dilemma.

Abstract:

:The data from population-based, randomized trials of the mammographic screening of women aged 40 to 49 years are limited by retrospective subgroup analysis, low statistical power, and the use of older mammographic techniques. Nonetheless, meta-analysis involving the most recently reported data from all similarly designed trials shows a 21% mortality reduction in women who have had mammographic screening compared with those in control groups, a statistically significant difference (upper bound of 95% Cl, 0.98). Evidence from modern mammography demonstration projects (which are limited by a lack of control groups and the unavailability of mortality results) also shows that the tumor size, axillary lymph node status, and stage of screening-detected breast cancers in women aged 40 to 49 years indicate that screening is at least as beneficial for these women as it is for those aged 50 to 64 years, for whom mammographic screening is widely accepted. Overall, the evidence suggests that screening will benefit women aged 40 to 49 years, but some argue that the level of proof provided is not rigorous enough to establish the efficacy of screening. In the United States, more than 10,000 deaths per year occur among women who develop breast cancer between the ages of 40 and 49. Thousands of lives are probably lost each year because women are not being screened. We believe that it is much more prudent to endorse mammographic screening now, risking the unlikely subsequent determination that the effort was ineffective, than to withhold screening until it is determined whether "proof" of efficacy will be obtained, risking the loss of so many lives. We urge primary care practitioners to recommend routine mammography for women aged 40 to 49 years.

journal_name

Ann Intern Med

authors

Sickles EA,Kopans DB

doi

10.7326/0003-4819-122-7-199504010-00010

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

534-8

issue

7

eissn

0003-4819

issn

1539-3704

journal_volume

122

pub_type

杂志文章,评审
  • In ACS, prasugrel reduces 30-day MACE and mortality vs. ticagrelor or clopidogrel; no differences for major bleeding.

    abstract:SOURCE CITATION:Baldetti L, Melillo F, Moroni F, et al. Meta-analysis comparing P2Y12 inhibitors in acute coronary syndrome. Am J Cardiol. 2020;125;1815-22. 32305225. ...

    journal_title:Annals of internal medicine

    pub_type: 评论,杂志文章

    doi:10.7326/ACPJ202009150-027

    authors: Elgendy IY

    更新日期:2020-09-15 00:00:00

  • Using Behavioral Economics to Design Physician Incentives That Deliver High-Value Care.

    abstract::Behavioral economics provides insights about the development of effective incentives for physicians to deliver high-value care. It suggests that the structure and delivery of incentives can shape behavior, as can thoughtful design of the decision-making environment. This article discusses several principles of behavio...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M15-1330

    authors: Emanuel EJ,Ubel PA,Kessler JB,Meyer G,Muller RW,Navathe AS,Patel P,Pearl R,Rosenthal MB,Sacks L,Sen AP,Sherman P,Volpp KG

    更新日期:2016-01-19 00:00:00

  • Cost-effectiveness of transesophageal echocardiography to determine the duration of therapy for intravascular catheter-associated Staphylococcus aureus bacteremia.

    abstract:BACKGROUND:The appropriate duration of therapy for catheter-associated Staphylococcus aureus bacteremia is controversial. Conventional practice dictates that all patients receive prolonged courses of intravenous antibiotics. Some clinicians recommend abbreviated therapeutic courses, but an alternate approach involves p...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-130-10-199905180-00004

    authors: Rosen AB,Fowler VG Jr,Corey GR,Downs SM,Biddle AK,Li J,Jollis JG

    更新日期:1999-05-18 00:00:00

  • Physical activity and osteoporotic fracture risk in older women. Study of Osteoporotic Fractures Research Group.

    abstract:BACKGROUND:Physical activity has been related to enhanced bone mass and improved physical functioning and thus may reduce the risk for osteoporotic fracture. OBJECTIVE:To determine whether higher levels of physical activity are related to lower incidence of hip, wrist, and vertebral fractures. DESIGN:Prospective coho...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-129-2-199807150-00002

    authors: Gregg EW,Cauley JA,Seeley DG,Ensrud KE,Bauer DC

    更新日期:1998-07-15 00:00:00

  • Accuracy of rapid influenza diagnostic tests: a meta-analysis.

    abstract:BACKGROUND:Timely diagnosis of influenza can help clinical management. PURPOSE:To examine the accuracy of rapid influenza diagnostic tests (RIDTs) in adults and children with influenza-like illness and evaluate factors associated with higher accuracy. DATA SOURCES:PubMed and EMBASE through December 2011; BIOSIS and W...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/0003-4819-156-7-201204030-00403

    authors: Chartrand C,Leeflang MM,Minion J,Brewer T,Pai M

    更新日期:2012-04-03 00:00:00

  • Neuroblastoma: clinical perspectives, monoclonal antibodies, and retinoic acid.

    abstract::Neuroblastoma, the second commonest solid tumor in children, is a neoplasm of the peripheral autonomic nervous system that usually occurs before children are 6 years old. Therapy of localized tumor (clinical stage I and II) and of a special form of metastatic tumor (clinical stage IV-S) is usually successful, but trea...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-97-6-873

    authors: Seeger RC,Siegel SE,Sidell N

    更新日期:1982-12-01 00:00:00

  • A reassessment of the importance of "low-count" bacteriuria in young women with acute urinary symptoms.

    abstract:OBJECTIVE:To determine whether a statistical association exists between "low-count" bacteriuria (> 10(2) to 10(4) colony-forming units/mL) and acute urinary symptoms in young women. DESIGN:Prospective, case-control study. SETTING:Gynecology clinic at a student health center. PATIENTS:Women with or without urinary or...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-119-6-199309150-00002

    authors: Kunin CM,White LV,Hua TH

    更新日期:1993-09-15 00:00:00

  • When doctors marry doctors: a survey exploring the professional and family lives of young physicians.

    abstract:BACKGROUND:Soon, half of all physicians may be married to other physicians (that is, in dual-doctor families). Little is known about how marriage to another physician affects physicians themselves. OBJECTIVE:To learn how physicians in dual-doctor families differ from other physicians in their professional and family l...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-130-4-199902160-00017

    authors: Sobecks NW,Justice AC,Hinze S,Chirayath HT,Lasek RJ,Chren MM,Aucott J,Juknialis B,Fortinsky R,Youngner S,Landefeld CS

    更新日期:1999-02-16 00:00:00

  • Sudden cardiac death: management of high-risk patients.

    abstract::Sudden cardiac death remains a leading cause of death in the United States, accounting for more than 350,000 deaths each year, and the survival rate of victims remains low. Most survivors face a significant risk for recurrence. The typical substrate is chronic--abnormal myocardium with fibrosis (often from previous my...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-114-6-499

    authors: Akhtar M,Garan H,Lehmann MH,Troup PJ

    更新日期:1991-03-15 00:00:00

  • Adenosine for paroxysmal supraventricular tachycardia: dose ranging and comparison with verapamil. Assessment in placebo-controlled, multicenter trials. The Adenosine for PSVT Study Group.

    abstract:OBJECTIVE:To assess the safety and efficacy of intravenous adenosine in terminating acute episodes of paroxysmal supraventricular tachycardia. DESIGN:Two prospective, double-blind, randomized, placebo-controlled trials to evaluate dose response in patients receiving adenosine and to compare the effects of adenosine wi...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-113-2-104

    authors: DiMarco JP,Miles W,Akhtar M,Milstein S,Sharma AD,Platia E,McGovern B,Scheinman MM,Govier WC

    更新日期:1990-07-15 00:00:00

  • Sodium etidronate in the treatment of Paget's disease of bone. A study of long-term results.

    abstract::Subjects (109) with symptomatic Paget's disease of bone were treated with 5, 10, or 20 mg of sodium etidronate (EHDP)/kg body weight - day for 6 to 24 months. Significant decreases in serum alkaline phosphatase and urinary hydroxyproline were noted after 6 months of therapy; no significant further improvement resulted...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章

    doi:10.7326/0003-4819-87-6-656

    authors: Khairi MR,Altman RD,DeRosa GP,Zimmermann J,Schenk RK,Johnston CC

    更新日期:1977-12-01 00:00:00

  • Cyclophosphamide in the management of advanced Graves' ophthalmopathy. A preliminary report.

    abstract::Three patients with advanced Graves' ophthalmopathy were treated with cyclophosphamide. All had proptosis and diplopia. One patient had disabling iatrogenic Cushing's syndrome from steroid treatment of the ophthalmopathy and had undergone bilateral orbital decompression before cyclophosphamide therapy; steroids could ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-90-6-921

    authors: Bigos ST,Nisula BC,Daniels GH,Eastman RC,Johnston HH,Kohler PO

    更新日期:1979-06-01 00:00:00

  • Spondyloarthropathy associated with hidradenitis suppurative and acne conglobata.

    abstract::We evaluated 10 patients with hidradenitis suppurative or acne conglobata who developed arthritis. In contrast to patients with acne fulminans and arthritis, all our subjects were adults over 22 years of age; nine were black; and four were women. Nine patients had episodic inflammatory oligoarthritis affecting mainly ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-97-4-520

    authors: Rosner IA,Richter DE,Huettner TL,Kuffner GH,Wisnieski JJ,Burg CG

    更新日期:1982-10-01 00:00:00

  • Short-course therapy of catheter-related Staphylococcus aureus bacteremia: a meta-analysis.

    abstract:OBJECTIVE:To determine, through structured methodologic review of published articles, the effectiveness of short-course (< or = 2 weeks) antibiotic therapy for catheter-related Staphylococcus aureus bacteremia. DATA SOURCES:English-language publications on catheter-related S. aureus bacteremia identified using MEDLINE...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析

    doi:10.7326/0003-4819-119-4-199308150-00010

    authors: Jernigan JA,Farr BM

    更新日期:1993-08-15 00:00:00

  • Waldenström's macroglobulinemia and autoimmune disease in a family.

    abstract::We diagnosed Waldenström's macroglobulinemia in a father and three offspring. Clinical and subclinical autoimmune disorders occurred excessively in the family. The HLA haplotype A2, B8, DRw3 was detected in all patients with Waldenström's macroglobulinemia and all but one family member with autoimmune manifestations. ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-93-6-830

    authors: Blattner WA,Garber JE,Mann DL,McKeen EA,Henson R,McGuire DB,Fisher WB,Bauman AW,Goldin LR,Fraumeni JF Jr

    更新日期:1980-12-01 00:00:00

  • Menopausal hormone therapy for the primary prevention of chronic conditions: a systematic review to update the U.S. Preventive Services Task Force recommendations.

    abstract:BACKGROUND:Menopausal hormone therapy to prevent chronic conditions is currently not recommended because of its adverse effects. PURPOSE:To update evidence about the effectiveness of hormone therapy in reducing risk for chronic conditions and adverse effects, and to examine whether outcomes vary among women in differe...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-157-2-201207170-00466

    authors: Nelson HD,Walker M,Zakher B,Mitchell J

    更新日期:2012-07-17 00:00:00

  • Examination of links between herpes zoster incidence and childhood varicella vaccination.

    abstract:BACKGROUND:Introduction of a universal varicella vaccine program for U.S. children in 1996 sparked concern that less-frequent exposure to varicella would decrease external boosting of immunity to varicella zoster virus and thereby increase incidence of herpes zoster (HZ). OBJECTIVE:To determine whether the varicella v...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-159-11-201312030-00006

    authors: Hales CM,Harpaz R,Joesoef MR,Bialek SR

    更新日期:2013-12-03 00:00:00

  • Patient safety is not enough: targeting quality improvements to optimize the health of the population.

    abstract::Ensuring patient safety is essential for better health care, but preoccupation with niches of medicine, such as patient safety, can inadvertently compromise outcomes if it distracts from other problems that pose a greater threat to health. The greatest benefit for the population comes from a comprehensive view of popu...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-140-1-200401060-00009

    authors: Woolf SH

    更新日期:2004-01-06 00:00:00

  • Percutaneous transluminal angioplasty for renal artery stenosis in a solitary functioning kidney.

    abstract::In five patients with hypertension and marked impairment of renal function due to renal artery stenosis in a solitary functioning kidney, a nonsurgical technique, percutaneous transluminal angioplasty, was used to dilate the stenotic renal artery. Blood pressure improved in all five patients, and renal function improv...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-91-5-684

    authors: Weinberger MH,Yune HY,Grim CE,Luft FC,Klatte EC,Donohue JP

    更新日期:1979-11-01 00:00:00

  • Classification of acute leukemia.

    abstract::The classification of acute leukemia has almost invariably been based on the morphologic diagnosis into two broad categories: acute lymphocytic and acute myeloid leukemia. Despite the wide range of morphologic variation in both groups, strict criteria to define the subgroups have only recently been proposed. The conve...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-87-6-740

    authors:

    更新日期:1977-12-01 00:00:00

  • Accurate measurement of liver, kidney, and spleen volume and mass by computerized axial tomography.

    abstract::Computerized axial tomography permits accurate cross-sectional radiographic visualization of visceral organs. Thus, "radiographic area" of an organ slice can be calculated and converted to actual area from a standard grid printed on the roentgenogram. Because the width between slices is known, the volume of an organ s...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-90-2-185

    authors: Heymsfield SB,Fulenwider T,Nordlinger B,Barlow R,Sones P,Kutner M

    更新日期:1979-02-01 00:00:00

  • Transitional care interventions to prevent readmissions for persons with heart failure: a systematic review and meta-analysis.

    abstract:BACKGROUND:Nearly 25% of patients hospitalized with heart failure (HF) are readmitted within 30 days. PURPOSE:To assess the efficacy, comparative effectiveness, and harms of transitional care interventions to reduce readmission and mortality rates for adults hospitalized with HF. DATA SOURCES:MEDLINE, Cochrane Librar...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/M14-0083

    authors: Feltner C,Jones CD,Cené CW,Zheng ZJ,Sueta CA,Coker-Schwimmer EJ,Arvanitis M,Lohr KN,Middleton JC,Jonas DE

    更新日期:2014-06-03 00:00:00

  • Crystalluria and urinary tract abnormalities associated with indinavir.

    abstract:BACKGROUND:Indinavir, a protease inhibitor widely used to treat patients with HIV infection, has been associated with nephrolithiasis. Distinctive urinary crystals and a spectrum of urologic disorders were noted in patients receiving indinavir. OBJECTIVE:To determine the composition of urinary crystals and the frequen...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-127-2-199707150-00004

    authors: Kopp JB,Miller KD,Mican JA,Feuerstein IM,Vaughan E,Baker C,Pannell LK,Falloon J

    更新日期:1997-07-15 00:00:00

  • Digoxin for atrial fibrillation: a drug whose time has gone?

    abstract::For over 200 years digitalis compounds have been used to treat atrial fibrillation. The rapid ventricular response to atrial fibrillation is frequently treated with digoxin to produce a controlled heart rate. Digoxin has also been proposed as a treatment for terminating recent-onset atrial fibrillation, for maintainin...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-114-7-573

    authors: Falk RH,Leavitt JI

    更新日期:1991-04-01 00:00:00

  • Detection of aortic insufficiency by standard echocardiography, pulsed Doppler echocardiography, and auscultation. A comparison of accuracies.

    abstract::To determine the relative sensitivity and specificity of noninvasive methods for detecting aortic insufficiency, we compared the accuracy of auscultation, echocardiography, and pulsed Doppler echocardiography in detecting aortic insufficiency in 106 patients in whom the presence or absence of the lesion was shown by s...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-104-5-599

    authors: Grayburn PA,Smith MD,Handshoe R,Friedman BJ,DeMaria AN

    更新日期:1986-05-01 00:00:00

  • The Canadian Cardiovascular Society grading scale for angina pectoris: is it time for refinements?

    abstract:OBJECTIVE:To appraise the measurement properties of the Canadian Cardiovascular Society (CCS) classification of stable angina pectoris. DATA SOURCES:Relevant articles were identified through a MEDLINE search (1976 to November 1991). Bibliographies of retrieved articles were also reviewed. STUDY SELECTION:Studies chos...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-117-8-677

    authors: Cox J,Naylor CD

    更新日期:1992-10-15 00:00:00

  • Measuring the performance of markers for guiding treatment decisions.

    abstract::Treatment selection markers, sometimes called predictive markers, are factors that help clinicians select therapies that maximize good outcomes and minimize adverse outcomes for patients. Existing statistical methods for evaluating a treatment selection marker include assessing its prognostic value, evaluating treatme...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-154-4-201102150-00006

    authors: Janes H,Pepe MS,Bossuyt PM,Barlow WE

    更新日期:2011-02-15 00:00:00

  • The common hyperlipoproteinemias: an understanding of disease mechanisms and their control.

    abstract::Our review focuses on low density lipoprotein (LD lipoprotein) and very low density lipoprotein (VLD lipoprotein) in their roles as transporters of cholesterol and triglyceride and as factors contributing to premature arteriovascular disease. We describe the clinical manifestations of the common, primary hyperlipoprot...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-85-4-497

    authors: Fisher WR,Truitt DH

    更新日期:1976-10-01 00:00:00

  • Fatal Rhizopus infections in hemodialysis patients receiving deferoxamine.

    abstract::Four hemodialysis patients receiving deferoxamine for metal overload had fatal rhinocerebral rhizopus infections. Serious fungal infections are not commonly seen in patients on dialysis, and none of these patients had the usual risk factors for rhizopus infection. Deferoxamine is being used with increased frequency in...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-107-5-678

    authors: Windus DW,Stokes TJ,Julian BA,Fenves AZ

    更新日期:1987-11-01 00:00:00

  • Herpes simplex virus resistant to acyclovir. A study in a tertiary care center.

    abstract:STUDY OBJECTIVE:To determine the sensitivity of herpes simplex virus isolates to acyclovir and the importance of resistant isolates in hospitalized patients. DESIGN:Retrospective incidence cohort study. SETTING:All herpes simplex virus isolates cultured over 1 year from patients followed at a tertiary care center. P...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-76-3-112-6-416

    authors: Englund JA,Zimmerman ME,Swierkosz EM,Goodman JL,Scholl DR,Balfour HH Jr

    更新日期:1990-03-15 00:00:00