Waldenström's macroglobulinemia and autoimmune disease in a family.

abstract：OBJECTIVE:To compare trimethoprim-sulfamethoxazole (TMP-SMZ) and vancomycin regarding efficacy and safety in the therapy of serious Staphylococcus aureus infections. DESIGN:Randomized, double-blind comparative trial. SETTING:A tertiary-care hospital. PATIENTS:One hundred and one intravenous drug users hospitalized w...

journal_title：Annals of internal medicine

authors： Markowitz N,Quinn EL,Saravolatz LD

更新日期：1992-09-01 00:00:00

abstract：:Antibody to native DNA was measured by five techniques: the Crithidia luciliae immunofluorescence (CL-IF) test; filter radioimmunoassays using either untreated human KB DNA, endonuclease-treated KB DNA, or a synthetic polynucleotide (poly dAT); and the Farr immunoprecipitation assay using KB DNA. The specificity and s...

journal_title：Annals of internal medicine

authors： Chubick A,Sontheimer RD,Gilliam JN,Ziff M

更新日期：1978-08-01 00:00:00

abstract：:The management of asymptomatic hyperuricemia is controversial. Reported benefits from treatment prevention of acute gouty arthritis, chronic tophaceous gout, urolithiasis, or gouty nephropathy. A review of experimental and clinical data suggests that the risks of asymptomatic hyperuricemia are small or unknown and the...

journal_title：Annals of internal medicine

authors： Liang MH,Fries JF

更新日期：1978-05-01 00:00:00

abstract：:Meningitis caused by enteric gram-negative bacilli is relatively uncommon but is very difficult to treat despite susceptibility in vitro to many antimicrobics. A major problem appears to be poor entry of many drugs into the central nervous system. Moxalactam is an investigational cephalosporin that attains concentrati...

journal_title：Annals of internal medicine

authors： Olson DA,Hoeprich PD,Nolan SM,Goldstein E

更新日期：1981-09-01 00:00:00

abstract：OBJECTIVE:To determine risk factors for community-acquired and nosocomial group B streptococcal disease in adults. DESIGN:Case-control study. SETTING:3 metropolitan areas in the United States with an aggregate population of 6.6 million persons. PATIENTS:219 nonpregnant adults with invasive group B streptococcal infe...

journal_title：Annals of internal medicine

authors： Jackson LA,Hilsdon R,Farley MM,Harrison LH,Reingold AL,Plikaytis BD,Wenger JD,Schuchat A

更新日期：1995-09-15 00:00:00

abstract：:Impairment of penicillin G excretion in renal failure may result in life-threatening, dose-related toxicity. We report a method for achieving a desired mean serum penicillin G concentration in patients with renal failure, with minimal risk of both undertreatment and drug toxicity. The method is based on the linear rel...

journal_title：Annals of internal medicine

authors： Bryan CS,Stone WJ

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:The risk for hypertension after kidney donation remains uncertain. PURPOSE:To see whether normotensive adults who donate a kidney develop higher blood pressure and risk for hypertension compared with nondonor adults acting as control participants. DATA SOURCES:MEDLINE, EMBASE, and Science Citation Index we...

journal_title：Annals of internal medicine

authors： Boudville N,Prasad GV,Knoll G,Muirhead N,Thiessen-Philbrook H,Yang RC,Rosas-Arellano MP,Housawi A,Garg AX,Donor Nephrectomy Outcomes Research (DONOR) Network.

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Increased prevalence of adolescent obesity requires effective treatment options beyond behavior therapy. OBJECTIVE:To see whether sibutramine reduced weight more than placebo in obese adolescents who were receiving a behavior therapy program. DESIGN:12-month, 3:1 randomized, double-blind trial conducted fr...

journal_title：Annals of internal medicine

authors： Berkowitz RI,Fujioka K,Daniels SR,Hoppin AG,Owen S,Perry AC,Sothern MS,Renz CL,Pirner MA,Walch JK,Jasinsky O,Hewkin AC,Blakesley VA,Sibutramine Adolescent Study Group.

更新日期：2006-07-18 00:00:00

abstract：:Advances through basic research have elucidated the disturbances of neurotransmitter function in Parkinson's Dopamine has replaced acetylcholine and norepinephrine as the most studied neurotransmitter, with both conceptual and practical developments, exemplified by the hypothesis of cyclic adenosine monophosphate as a...

journal_title：Annals of internal medicine

authors： Calne DB,Kebabian J,Silbergeld E,Evarts E

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Many dispensing errors made in hospital pharmacies can harm patients. Some hospitals are investing in bar code technology to reduce these errors, but data about its efficacy are limited. OBJECTIVE:To evaluate whether implementation of bar code technology reduced dispensing errors and potential adverse drug ...

journal_title：Annals of internal medicine

authors： Poon EG,Cina JL,Churchill W,Patel N,Featherstone E,Rothschild JM,Keohane CA,Whittemore AD,Bates DW,Gandhi TK

更新日期：2006-09-19 00:00:00

abstract：BACKGROUND:Pharmacologic thromboprophylaxis reduces the risk for venous thromboembolism after total hip replacement (THR) or total knee replacement (TKR). New oral anticoagulants (NOACs), including direct thrombin inhibitors and factor Xa inhibitors, are emerging options for thromboprophylaxis after these procedures. ...

journal_title：Annals of internal medicine

authors： Adam SS,McDuffie JR,Lachiewicz PF,Ortel TL,Williams JW Jr

更新日期：2013-08-20 00:00:00

abstract：:Multiple myeloma raises a number of puzzling questions about the production of immunoglobulins and the malignant transformation of lymphoid cells. Some of these questions can be approached by studying mouse plasmacytomas and by genetic and biochemical studies of mouse myeloma cells in culture. The synthesis, assembly,...

journal_title：Annals of internal medicine

authors： Weitzman S,Margulies DH,Scharff MD

更新日期：1976-07-01 00:00:00

abstract：:Sera of 24 patients with an unexplained pneumonia were tested for the presence of antibodies against the Legionnaires' disease bacterium. Fifteen patients had positive serology. The series comprised 12 male and three female patients ranging in age from 17 to 66 years (mean, 51.1 years). All of the patients had a high ...

journal_title：Annals of internal medicine

authors： Meenhorst PL,van der Meer JW,Borst J

更新日期：1979-04-01 00:00:00

abstract：:We performed immunohistopathologic studies on biopsied lung tissue obtained from two patients with lupus pneumonitis using immunofluorescence, immunoperoxidase, electron microscopy, and acid-microelution. In both patients, immunofluorescence showed granular deposits of IgG, the third component of complement (C3), and ...

journal_title：Annals of internal medicine

authors： Inoue T,Kanayama Y,Ohe A,Kato N,Horiguchi T,Ishii M,Shiota K

更新日期：1979-07-01 00:00:00

abstract：:Large-scale, epidemic transmission of tuberculosis to patients, nonprofessional staff, nurses, and physicians has been documented recently in hospitals, clinics, acquired immunodeficiency syndrome (AIDS) residencies, and correctional facilities. Prominent factors in these outbreaks have included human immunodeficiency...

journal_title：Annals of internal medicine

authors： Iseman MD

更新日期：1992-08-01 00:00:00

abstract：:Acute bronchitis is an acute cough illness in otherwise healthy adults that usually lasts 1 to 3 weeks. This review describes the pathophysiology of the condition and provides a practical approach to the evaluation and treatment of adults with uncomplicated acute bronchitis. Practical points to be made are:1. Respirat...

journal_title：Annals of internal medicine

authors： Gonzales R,Sande MA

更新日期：2000-12-19 00:00:00

abstract：:Bioethics has become a common course of study in medical schools, other health professional schools, and graduate and undergraduate programs. An analysis of past ethical scandals, as well as the bioethics apparatus that emerged in response to them, is often central to the discussion of bioethical questions. This histo...

journal_title：Annals of internal medicine

authors： Lerner BH,Caplan AL

更新日期：2016-04-19 00:00:00

abstract：BACKGROUND:The comparative effectiveness of rheumatoid arthritis therapies is uncertain. PURPOSE:To compare the benefits and harms of disease-modifying antirheumatic drugs (DMARDs) for adults with rheumatoid arthritis. DATA SOURCES:Records limited to the English language and studies of adults were identified by using...

journal_title：Annals of internal medicine

authors： Donahue KE,Gartlehner G,Jonas DE,Lux LJ,Thieda P,Jonas BL,Hansen RA,Morgan LC,Lohr KN

更新日期：2008-01-15 00:00:00

abstract：PURPOSE:To review the literature on prevention of intravascular catheter-related infections. DATA SOURCES:The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. Primary authors were contacted directly if data were incomplete. STUDY SE...

journal_title：Annals of internal medicine

authors： Mermel LA

更新日期：2000-03-07 00:00:00

abstract：PURPOSE:To examine the cost-effectiveness of test-treatment strategies for patients suspected of having Lyme disease. DATA SOURCES:The medical literature was searched for information on outcomes and costs. Expert opinion was sought for information on utilities. STUDY SELECTION:Articles that described patient populati...

journal_title：Annals of internal medicine

authors： Nichol G,Dennis DT,Steere AC,Lightfoot R,Wells G,Shea B,Tugwell P

更新日期：1998-01-01 00:00:00

abstract：:This issue provides a clinical overview of plantar fasciitis focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual subscribers can access the electronic features of In the Clinic. Non-...

journal_title：Annals of internal medicine

authors： Young C

更新日期：2012-01-03 00:00:00

abstract：:The latest guidelines from the American College of Cardiology and American Heart Association, released in fall 2013, provide a long-anticipated update to the recommendations of the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol ...

journal_title：Annals of internal medicine

authors： Cook NR,Ridker PM

更新日期：2016-12-06 00:00:00

abstract：SOURCE CITATION:Cao B, Wang Y, Wen D, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19. N Engl J Med. 2020;382:1787-99. 32187464. ...

journal_title：Annals of internal medicine

authors： Yang P,Tekwani S,Martin GS

更新日期：2020-06-16 00:00:00

abstract：:The Advisory Committee on Immunization Practices (ACIP) consists of 15 experts in immunization and related fields, selected by the Secretary of the U.S. Department of Health and Human Services, to provide advice and guidance on control of vaccine-preventable diseases. In its role as a federal advisory committee, the A...

journal_title：Annals of internal medicine

authors： Smith JC,Snider DE,Pickering LK,Advisory Committee on Immunization Practices.

更新日期：2009-01-06 00:00:00

abstract：:Recent national recommendations have proposed that physicians should titrate lipid therapy to achieve low-density lipoprotein (LDL) cholesterol levels less than 1.81 mmol/L (<70 mg/dL) for patients at very high cardiovascular risk and less than 2.59 mmol/L (<100 mg/dL) for patients at high cardiovascular risk. To exam...

journal_title：Annals of internal medicine

authors： Hayward RA,Hofer TP,Vijan S

更新日期：2006-10-03 00:00:00

abstract：:Identical male twins had alveolar cell carcinoma with nearly synchronous onset and similar histopathologic features, both metastatic to the brain. The hypothesis is advanced that there are genes shared by these twins that determine not only the susceptibility of pulmonary cells to malignant transformation but also the...

journal_title：Annals of internal medicine

authors： Joishy SK,Cooper RA,Rowley PT

更新日期：1977-10-01 00:00:00

abstract：Background:Little is known about whether insurance expansion affects the location and type of emergency department (ED) use. Understanding these changes can inform state-level decisions about the Medicaid expansion under the Patient Protection and Affordable Care Act (ACA). Objective:To investigate the effect of the 2...

journal_title：Annals of internal medicine

authors： Garthwaite C,Gross T,Notowidigdo M,Graves JA

更新日期：2017-02-07 00:00:00

abstract：:Women comprise more than one third of the active physician workforce, an estimated 46% of all physicians-in-training, and more than half of all medical students in the United States. Although progress has been made toward gender diversity in the physician workforce, disparities in compensation exist and inequities hav...

journal_title：Annals of internal medicine

authors： Butkus R,Serchen J,Moyer DV,Bornstein SS,Hingle ST,Health and Public Policy Committee of the American College of Physicians.

更新日期：2018-05-15 00:00:00

abstract：:A severe shortage of organs greatly limits the ability to deliver the miracle of transplantation to people suffering from end-stage organ disease. Contributing to this shortage is a high rate of refusal among families who are asked for permission to remove organs from a recently deceased relative. Mandated choice offe...

journal_title：Annals of internal medicine

authors： Spital A

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Elevated blood pressure (BP) is the largest contributing risk factor to all-cause and cardiovascular mortality. PURPOSE:To update a systematic review on the benefits and harms of screening for high BP in adults and to summarize evidence on rescreening intervals and diagnostic and predictive accuracy of diff...

journal_title：Annals of internal medicine

authors： Piper MA,Evans CV,Burda BU,Margolis KL,O'Connor E,Whitlock EP

更新日期：2015-02-03 00:00:00