Abstract:
:Rhodotorula species are emerging pathogens in immunocompromised patients. We report the in vitro activities of eight antifungals against 64 Rhodotorula isolates collected in surveillance programs between 1987 and 2003. Rhodotorula strains are resistant in vitro to fluconazole (MIC at which 50% of the isolates tested are inhibited [MIC(50)], >128 microg/ml) and caspofungin (MIC(50), >8 microg/ml). Amphotericin B (MIC(50),1 microg/ml) and flucytosine (MIC(50), 0.12 microg/ml) are both active in vitro, and the new and investigational triazoles all have some in vitro activity, with ravuconazole being the most active (MIC(50), 0.25 microg/ml).
journal_name
J Clin Microbioljournal_title
Journal of clinical microbiologyauthors
Diekema DJ,Petroelje B,Messer SA,Hollis RJ,Pfaller MAdoi
10.1128/JCM.43.1.476-478.2005subject
Has Abstractpub_date
2005-01-01 00:00:00pages
476-8issue
1eissn
0095-1137issn
1098-660Xpii
43/1/476journal_volume
43pub_type
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