Abstract：
:Apoptosis and inflammation are important cellular processes that are highly regulated through specific protein-protein interactions (PPI). Proteins involved in these signaling cascades often carry PPI domains that belong to the death-domain superfamily. This includes the structurally well-characterized Death Domain (DD), the Death Effector Domain (DED) and the Caspase Recruitment Domain (CARD) subfamilies. Recently, a fourth member of the DD superfamily was identified, the Pyrin Domain (PYD). Based on sequence alignments, homology to other domains occurring in death-signalling pathways, and secondary-structure prediction, the PYD was predicted to have an overall fold similar to other DD superfamily members. Just recently, NMR structures of two PYDs have been determined. The PYD structures not only revealed the DD superfamily fold as previously predicted, but also distinct features that are characteristic exclusively for this subfamily. This review summarizes recent findings and developments regarding structural aspects of the DD superfamily, with a special emphasis on the PPIs of the DD superfamily.
journal_name
C R Bioljournal_title
Comptes rendus biologiesauthors
Kohl A,Grütter MGdoi
10.1016/j.crvi.2004.08.006subject
Has Abstractpub_date
2004-12-01 00:00:00pages
1077-86issue
12eissn
1631-0691issn
1768-3238pii
S1631-0691(04)00189-1journal_volume
327pub_type
杂志文章,评审abstract：:Meiosis is a specialized cell division at the origin of the haploid cells that eventually develop into the gametes. It therefore lies at the heart of Mendelian heredity. Recombination and redistribution of the homologous chromosomes arising during meiosis constitute an important source of genetic diversity, conferring...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2016.04.003
更新日期：2016-07-01 00:00:00
abstract：:Although there are many types of epilepsy of both genetic and acquired forms, temporal lobe epilepsy (TLE) with hippocampal sclerosis is probably the single most common human epilepsy, and the one most intensely studied. Despite a wealth of descriptive data obtained from patient histories, imaging techniques, electroe...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2004.10.010
更新日期：2005-02-01 00:00:00
abstract：:Submerged fermentation in a stirred bioreactor of the white rot fungus Cerrena unicolor C-139 was done at a 120-L scale in the presence of wheat bran as a cheap lignocellulosic substrate for fungus growth and laccase production. Enzyme monitoring showed that laccase production started after 2 days of cultivation, atta...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2014.12.001
更新日期：2015-02-01 00:00:00
abstract：:This study aimed at showing the applicability of using a combination of four sampling methods (i.e., Winkler extractors, pitfall traps, baiting and manual collection), something most often conducted in the tropics, to create an inventory of ant species diversity in temperate environments. We recorded a total of 33 ant...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2007.08.012
更新日期：2007-12-01 00:00:00
abstract：:The evidence for amphibian population declines is based on count data that were not adjusted for detection probabilities. Such data are not reliable even when collected using standard methods. The formula C = Np (where C is a count, N the true parameter value, and p is a detection probability) relates count data to de...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(03)00048-9
更新日期：2003-08-01 00:00:00
abstract：:The first veterinary school in the world was created in Lyon in 1761 by an equerry, Claude Bourgelat (1712-1779), a man renowned for his skill in horsemanship and horse medicine, a man fully able to understand the issues of his time. Aware of the scope of the physiocratic movement and of the need to improve the health...
journal_title：Comptes rendus biologies
pub_type： 传,历史文章,杂志文章,评审
doi：10.1016/j.crvi.2012.02.005
更新日期：2012-05-01 00:00:00
abstract：:In the frame of the largest French project of artificial production reefs, initiated by the city of Marseilles in 2001, the present study aimed at describing the hydrodynamic pattern of the coastal area considered, by the use of a 3D numerical modelling. Results were local wind statistics, bottom current fields and dr...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2006.04.002
更新日期：2006-07-01 00:00:00
abstract：:This paper suggests three additions to the Hildebrand method for gait-pattern specification. The first allows an extension of this method by the use of the forelimb as reference. Thus, dataset could be gathered indifferently from fore or hindlimbs cycles to identify a symmetrical gait or compare gaits of diverse speci...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2003.11.005
更新日期：2004-02-01 00:00:00
abstract：:Two aspects of psychology and physiology of time are dealt with in this paper: the way time perception was increasingly studied during the 19th century by scientists, including many physicists, and the way the temporal properties of the nervous system were discovered and explored by physiologists. The neurophysiologic...
journal_title：Comptes rendus biologies
pub_type： 历史文章,杂志文章
doi：10.1016/j.crvi.2006.03.004
更新日期：2006-05-01 00:00:00
abstract：:In a previous study, we showed that estimates of the BSE epidemic in France were censored by cattle mortality and by a lack of diagnosis. Indeed, we estimated that 51 300 cattle were infected by the BSE agent between 1987 and 1997, whereas only 103 clinical BSE cases were detected by the passive surveillance system up...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2005.12.004
更新日期：2006-02-01 00:00:00
abstract：:A field experiment was conducted with paddy (Oryza sativa L.) irrigated with different concentrations (Control, 2.5, 5, 10, 25, 50, 75, 100 and 200 mg/l) of chromium. The changes in growth, yield, nutrient content and chromium accumulation in the paddy are reported. The growth of shoot, root, total leaf area, fresh we...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2010.03.002
更新日期：2010-08-01 00:00:00
abstract：:Advances in pharmacology and genomics, and their intervention in human biology are beyond our abilities to understand their consequences. Therapeutic intervention in highly complex, non-linear, adaptive biological systems results in some unforeseen and undesirable consequences. To do the most good with the least harm,...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2003.09.006
更新日期：2003-10-01 00:00:00
abstract：:The biological effect of seasonality on cadmium, lead and metallothionein contents was assessed in mussels Mytilus galloprovincialis from natural banks located along the coastline of the Gulf of Naples (Campania, Italy). Heavy metals and metallothionein concentrations were measured in digestive and reproductive glands...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2014.05.003
更新日期：2014-07-01 00:00:00
abstract：:Prevention against the weapons of bioterrorists is limited by the multiplicity of agents that could be used. Against smallpox, stocks of the classical vaccine must be prepared, but this vaccine is dangerous and we must look for a new and safer vaccine. A vaccine against anthrax is probably possible relatively soon. On...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(02)01504-4
更新日期：2002-08-01 00:00:00
abstract：:Epilithic diatom communities are particularly suitable for the evaluation of freshwater quality. In Ecuador, however, no water quality index includes this biotic parameter. This work is the first attempt in the country to determine the composition of epilithic diatom communities associated with different degrees of eu...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2018.03.008
更新日期：2018-04-01 00:00:00
abstract：:Cnidarians (corals and sea anemones) harbouring photosynthetic microalgae derive several benefits from their association. To allow this association, numerous symbiotic-dependent adaptations in both partners, resulting from evolutionary pressures, have been selected. The dinoflagellate symbionts (zooxanthellae) are loc...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2018.03.007
更新日期：2018-01-01 00:00:00
abstract：:A number of different neuropeptides exert powerful concerted controls on feeding behavior and energy balance, most of them being produced in hypothalamic neuronal networks under stimulation by anabolic and catabolic peripheral hormones such as ghrelin and leptin, respectively. These peptide-expressing neurons intercon...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2006.03.021
更新日期：2006-08-01 00:00:00
abstract：:Spermiogenesis in Robphildollfusium fractum begins with the formation of a differentiation zone containing: two centrioles, each bearing striated rootlets, nucleus, several mitochondria and an intercentriolar body constituted by seven electron-dense layers. The two centrioles originate two free flagella growing orthog...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2012.06.003
更新日期：2012-07-01 00:00:00
abstract：:Psychometric tests obtained from 6564 young men were studied as a function of the parents' ages at conception and of some characteristics of the subject's postnatal environment. Individual scores, from 0 to 20, were divided into two groups: n(1)11 and n(2)<11. In univariate analysis, scores <11 were respectively relat...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2009.02.008
更新日期：2009-07-01 00:00:00
abstract：:More than 5 years after the description of the first cases of variant Creutzfeldt-Jakob disease (vCJD), there is still great uncertainty about the size of the vCJD epidemic in the United Kingdom (UK), although the most recent predictions based on statistical modelling are more optimistic than the previous ones. The nu...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(02)01410-5
更新日期：2002-01-01 00:00:00
abstract：:Leaves, which play an essential role in plant photosynthesis, share common features such as being flat structures, but also show an impressive variability in their sizes and shapes. Following its initiation in the meristems, leaf development is patterned along three polarization axes to establish its basic architectur...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2010.01.013
更新日期：2010-04-01 00:00:00
abstract：:Cleome is the largest genus in the family Cleomaceae and it is known for its various medicinal properties. Recently, some species from the Cleome genus (Cleome viscosa, Cleome chelidonii, Cleome felina and Cleome speciosa) are split into genera Corynandra (Corynandra viscosa, Corynandra chelidonii, Corynandra felina),...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2016.02.005
更新日期：2016-03-01 00:00:00
abstract：:Mussels of the subfamily Bathymodiolinae thrive around chimneys emitting hot fluids at deep sea hydrothermal vents, as well as at cold seeps and on sunken organic debris (sunken wood, whale falls). Despite the absence of light-driven primary production in these deep-sea ecosystems, mussels succeed reaching high biomas...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2008.08.003
更新日期：2009-02-01 00:00:00
abstract：:In this paper we consider cell cycle models for which the transition operator for the evolution of birth mass density is a simple, linear dynamical system with a stochastic perturbation. The convolution model for a birth mass distribution is presented. Density functions of birth mass and tail probabilities in n-th gen...
journal_title：Comptes rendus biologies
pub_type： 杂志文章,评审
doi：10.1016/j.crvi.2003.05.002
更新日期：2004-03-01 00:00:00
abstract：:The soil macrofauna of a pure beech (PS) and a mixed beech-hornbeam (MS) stand was recorded using a sample design spatially explicit at stand level. Humic epipedon morphological and chemical properties, relative irradiance, soil bulk density, and the specific composition of the litter in MS were also investigated. The...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2004.10.008
更新日期：2005-01-01 00:00:00
abstract：:Enhanced stop codon readthrough is a potential treatment strategy for diseases caused by nonsense mutations. Here, we compare readthrough levels induced by three types of factors: aminoglycoside antibiotics, suppressor tRNAs, and factors decreasing translation termination efficiency. We show that the highest levels of...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2006.09.001
更新日期：2007-01-01 00:00:00
abstract：:The aim of this work is to assess the use of (SPOT) multispectral visible infrared remote sensing to study microphytobentos assemblages in a shellfish ecosystem (Bay of Bourgneuf, France). SPOT satellite images (acquired at low tide in spring or autumn between 1986 and 1998) were calibrated using in situ radiometric d...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/s1631-0691(03)00125-2
更新日期：2003-04-01 00:00:00
abstract：:This study was undertaken to assess the risk of poisoning due to consumption of the puffer fish Lagocephalus lagocephalus collected along the Tunisian coast. Wistar rats were daily intraperitoneally injected, for 10 days, with acidic extracts of liver or flesh (muscles + skin) of L. lagocephalus. Control rats received...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2008.05.005
更新日期：2008-08-01 00:00:00
abstract：:Choosing a suitable habitat is a main step in the settlement process, particularly for species having weak movement abilities. Reliable cues are thus needed for habitat selection. In silk-spinning arthropods, silk can be used as a social cue to select an appropriate location. Silk can also provide information on the p...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2012.07.001
更新日期：2012-08-01 00:00:00
abstract：:A new high-elevation scorpion species of the genus Scorpiops is described from the Indian state of Himachal Pradesh. Scorpiops spitiensis sp. nov. is the second highest-elevation scorpion species in Asia and the first one from India occurring at elevations above 4200 m. The new species closely resembles Scorpiops pete...
journal_title：Comptes rendus biologies
pub_type： 杂志文章
doi：10.1016/j.crvi.2014.04.004
更新日期：2014-06-01 00:00:00
