Abstract：
:This study was undertaken to assess the risk of poisoning due to consumption of the puffer fish Lagocephalus lagocephalus collected along the Tunisian coast. Wistar rats were daily intraperitoneally injected, for 10 days, with acidic extracts of liver or flesh (muscles + skin) of L. lagocephalus. Control rats received injections of NaCl (0.9%). No mortality and no evident signs of neurotoxicity were recorded in treated rats. Conversely, treatment led to: (1) diarrhoea and body and organ (liver, kidney) weights loss; (2) oxidative stress evidenced by an increase in lipid peroxidation (TBARS) and conversely a decrease in antioxidant enzyme activities (SOD, catalase, GSH-Px) in tissues (blood cells, liver, kidneys); (3) a decrease in alanine aminotransferase (ALT) and alkaline phosphatase (ALP) activities in blood plasma.
journal_name
C R Bioljournal_title
Comptes rendus biologiesauthors
Saoudi M,Abdelmouleh A,Kammoun W,Ellouze F,Jamoussi K,El Feki Adoi
10.1016/j.crvi.2008.05.005subject
Has Abstractpub_date
2008-08-01 00:00:00pages
611-6issue
8eissn
1631-0691issn
1768-3238pii
S1631-0691(08)00136-4journal_volume
331pub_type
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journal_title：Comptes rendus biologies
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journal_title：Comptes rendus biologies
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journal_title：Comptes rendus biologies
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journal_title：Comptes rendus biologies
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