Abstract:
:Prior work has shown that concentration profiles of platelets in flowing whole blood and of platelet-sized beads in flowing blood suspensions can include near-wall excesses. A model to describe this phenomenon was built about a single-component convective diffusion equation. To incorporate redistribution to preferred sites by shear flows of red cell suspensions, the model used a drift shape function (in addition to the commonly used augmented diffusion coefficient). This paper reports experiments that provide an average concentration profile from which the shape function for that model is calculated; the experiments and shape function are for the particular conditions of 40% hematocrit, platelet-sized latex beads (2.5 microns diameter), tube ID of 217 microns, and a wall shear rate of 555 s-1. Less precise estimates of the shape function obtained from data of previous studies indicate that the shape function is similar for the hematocrit of 15%.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Yeh C,Calvez AC,Eckstein ECdoi
10.1016/S0006-3495(94)80595-8subject
Has Abstractpub_date
1994-09-01 00:00:00pages
1252-9issue
3eissn
0006-3495issn
1542-0086pii
S0006-3495(94)80595-8journal_volume
67pub_type
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