Abstract:
:The stability of the 1:1 complex of sodium ion with the dianion of guanosine 5'-monophosphate has been determined by means of a potentiometric titration employing a specific ion electrode. The stability constant for the reaction Na(+) + 5'-GMP(2-) Na(5'-GMP)(-) was found to be 2.85 +/- 0.36 M(-1) at 5 degrees C and an ionic strength of 1.1 +/- 0.1 M. Although 5'-GMP forms ordered self-structures at high concentration in the presence of sodium ions, in dilute solution and at low sodium ion concentrations the Na(+) binding is weak and typical of that for other nucleotides.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Walmsley JA,Pinnavaia TJdoi
10.1016/s0006-3495(82)84564-5subject
Has Abstractpub_date
1982-06-01 00:00:00pages
315-8issue
3eissn
0006-3495issn
1542-0086pii
S0006-3495(82)84564-5journal_volume
38pub_type
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