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Reproducibility of gemifloxacin and comparison fluoroquinolone MIC results using Sensititre commercial dry-form panels.

Abstract：

:This study examined the ability of commercial dry-form broth microdilution panels (Sensititre, TREK Diagnostics, Cleveland, OH) to produce accurate minimum inhibitory concentration (MIC) results for gemifloxacin, a new fluoroquinolone. Reproducibility for gemifloxacin was 100.0% for on-scale values within +/-1 log2 dilution for same- and between-day comparisons. Newer comparator fluoroquinolones (sparfloxacin, sitafloxacin, and moxifloxacin) also showed excellent reproducibility (100.0%) for on-scale results analyzed at +/-1 log2 dilution for same- and between-day comparisons. Newer and investigational fluoroquinolone agents, including gemifloxacin, can be tested with confidence using these dry-form MIC panels.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Ross JE,Sader HS,Fritsche TR,Jones RN

doi

10.1016/j.diagmicrobio.2004.11.005

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

219-21

issue

3

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(04)00230-5

journal_volume

51

pub_type

杂志文章

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