Associations among exercise, body weight, and quality of life in a population-based sample of endometrial cancer survivors.

Abstract:

OBJECTIVES:Lack of exercise and excess body weight may exacerbate treatment-related declines in quality of life (QoL) in endometrial cancer survivors. The primary purpose of this study was to examine the associations among exercise, body weight, and QoL in a population-based sample of endometrial cancer survivors. METHODS:Participants were 386 endometrial cancer survivors residing in Alberta, Canada who completed a mailed survey that assessed self-reported exercise, height, and weight to calculate body mass index (BMI) and QoL using the Functional Assessment of Cancer Therapy-Anemia (FACT-An) scale. RESULTS:Descriptive data indicated that 70% of the sample were not meeting public health exercise guidelines and 72% were overweight or obese. Multivariate analyses of variance demonstrated that endometrial cancer survivors meeting public health guidelines for exercise and body weight reported significantly better QoL than survivors not meeting guidelines. The differences in QoL between the groups were clinically meaningful and were not altered when controlling for important demographic and medical variables. There were no interactions between exercise, BMI, age, or time since diagnosis. Lastly, multiple regression analysis identified that both exercise (beta = .21; P < .001) and BMI (beta = -.17; P < .001) were independently associated with QoL. CONCLUSIONS:These results suggest that exercise and body weight are important independent correlates of QoL in endometrial cancer survivors. Randomized controlled trials designed to test the causal effects of exercise and/or weight loss on QoL in endometrial cancer survivors are warranted.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Courneya KS,Karvinen KH,Campbell KL,Pearcey RG,Dundas G,Capstick V,Tonkin KS

doi

10.1016/j.ygyno.2005.01.007

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

422-30

issue

2

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(05)00033-8

journal_volume

97

pub_type

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