Involvement of the spleen in ovarian adenosquamous carcinoma.


:Classification of ovarian tumors according to FIGO does not take into account involvement of spleen. A patient who appears to be the first reported case of widespread carcinoma of the ovary with involvement of the splenic parenchyma is presented.


Gynecol Oncol


Gynecologic oncology


Glezerman M,Yanai-Inbar I,Charuzi I,Katz M,Glasner M,Piura B




Has Abstract


1988-05-01 00:00:00














  • Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype.

    abstract:OBJECTIVE:The objective of this study was to examine the clinicopathologic correlates of T-regulatory (T(reg)) cell infiltration in serous ovarian cancers and to define gene signatures associated with high T(reg)s. METHODS:Tumor infiltrating T(reg) and cytotoxic T-cells (CTLs) were quantitated in 232 primary serous ov...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Barnett JC,Bean SM,Whitaker RS,Kondoh E,Baba T,Fujii S,Marks JR,Dressman HK,Murphy SK,Berchuck A

    更新日期:2010-03-01 00:00:00

  • Necessity of routine cardiac evaluation in patients receiving pegylated liposomal doxorubicin for gynecologic cancer.

    abstract:OBJECTIVE:Pegylated liposomal doxorubicin (PLD) has similar reported clinical efficacy compared with conventional doxorubicin with less cardiotoxicity. The manufacturer of PLD advises that cardiac function should be evaluated with endomyocardial biopsy, echocardiography or multigated radionucleotide scan (MUGA) pre-tre...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Dioun SM,Vilardo N,Goldberg GL,Gressel GM

    更新日期:2019-11-01 00:00:00

  • Whole abdominal and pelvic irradiation in patients with minimal disease at second-look surgical reassessment for ovarian carcinoma.

    abstract::Aggressive cytoreductive surgery followed by combination chemotherapy for stage III ovarian carcinoma has resulted in a significant percentage of complete clinical responses. However, 30-50% of patients with no clinical evidence of disease are found to have residual carcinoma at second-look surgical reassessment. Beca...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Hoskins WJ,Lichter AS,Whittington R,Artman LE,Bibro MC,Park RC

    更新日期:1985-03-01 00:00:00

  • Magnetic resonance imaging performs better than endocervical curettage for preoperative prediction of cervical stromal invasion in endometrial carcinomas.

    abstract:OBJECTIVE:Preoperative identification of cervical stromal invasion in endometrial carcinoma is important to select patients for primary radical hysterectomy. The objective of this prospective implementation study was to assess if introduction of magnetic resonance imaging (MRI) in addition to the standardly applied end...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Haldorsen IS,Berg A,Werner HM,Magnussen IJ,Helland H,Salvesen OO,Trovik J,Salvesen HB

    更新日期:2012-09-01 00:00:00

  • Use of V-Y flap for vulvar reconstruction.

    abstract::Less extensive surgical treatment has become possible for limited vulvar cancer. However, primary closure is advisable only when the defect is minimal and tissue replacement is always needed in radical excisions. Local flaps are always considered the first choice because of their characteristics of similarity to the r...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Tateo A,Tateo S,Bernasconi C,Zara C

    更新日期:1996-08-01 00:00:00

  • Improved therapeutic index of lower dose topotecan chemotherapy in recurrent ovarian cancer.

    abstract:OBJECTIVE:Topotecan (1.5 mg/m(2)) administered daily for 5 consecutive days of a 21-day cycle is an established chemotherapeutic regimen in recurrent ovarian cancer. However, noncumulative myelosuppression has limited its use by many clinicians. We sought to determine whether a lower dose of topotecan could provide com...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rodriguez M,Rose PG

    更新日期:2001-11-01 00:00:00

  • How to make a hospital-based wound center financially viable: the Georgetown University Hospital model.

    abstract::As the medical need and expenditure for chronic wound care have increased markedly over the past decade, wound centers have grown exponentially throughout the country. They can be community-based or hospital-based, and in either case, can be run by the facility or by a national chain. The wound center's viability is d...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Attinger CE,Hoang H,Steinberg J,Couch K,Hubley K,Winger L,Kugler M

    更新日期:2008-11-01 00:00:00

  • Carcinoma of the cervix in association with uterine prolapse.

    abstract:BACKGROUND:Carcinoma of the cervix and a prolapsed uterus are common diseases in underdeveloped countries, but their association is quite rare. CASE:We report here the clinical characteristics of two Brazilian patients with carcinoma of the uterine cervix associated with a third-degree prolapsed uterus. The patients, ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: da Silva BB,da Costa Araújo R,Filho CP,Melo JA

    更新日期:2002-02-01 00:00:00

  • Risk of cardiovascular disease in women with BRCA1 and BRCA2 mutations.

    abstract:OBJECTIVE:Estimate the prevalence of cardiovascular disease risk factors and endpoints in women with BRCA mutations. METHODS:Women, age 40 and older, with BRCA mutations identified in Kaiser Permanente Northern California completed a questionnaire and underwent a lipid and fasting glucose panel. Bivariable analysis of...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Powell CB,Alabaster A,Armstrong MA,Stoller N,Raine-Bennett T

    更新日期:2018-12-01 00:00:00

  • Vulvar reconstruction using a mons pubis pedicle flap.

    abstract::The treatment of early vulvar carcinoma has moved toward less radical surgery with reconstruction. This report describes our preliminary experience with a mons pubis flap that is simple and appears safe, reliable, and gives excellent cosmetic and functional results following radical hemivulvectomy. Four patients have ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Potkul RK,Barnes WA,Barter JF,Delgado G,Spear SL

    更新日期:1994-10-01 00:00:00

  • Presentation of cervical cancer.

    abstract::To determine how patients with invasive cervical cancer present and whether presentation affects disease-free survival (DFS), a review of 81 patients treated for cervical cancer by the Division of Gynecologic Oncology and Pelvic Surgery at the Southern California Permanente Medical Group between January 1, 1986, and D...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Pretorius R,Semrad N,Watring W,Fotheringham N

    更新日期:1991-07-01 00:00:00

  • Applicability of the concept of "platinum sensitivity" to recurrent endometrial cancer: the SGSG-012/GOTIC-004/Intergroup study.

    abstract:OBJECTIVE:The concept of "platinum sensitivity" has been widely applied in the management of recurrent ovarian cancer. This study aimed to evaluate the applicability of this concept to recurrent endometrial cancer. PATIENTS AND METHODS:In this multicenter retrospective cohort study, the clinical data of patients with ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Nagao S,Nishio S,Michimae H,Tanabe H,Okada S,Otsuki T,Tanioka M,Fujiwara K,Suzuki M,Kigawa J

    更新日期:2013-12-01 00:00:00

  • Endometrial clear cell carcinoma metastatic to the paranasal sinuses: a case report and review of the literature.

    abstract:BACKGROUND:Paranasal sinus metastasis following endometrial carcinoma is extremely rare and a reflection of disseminated disease. CASE:We report a case of a 72-year-old woman who presented ethmoid and sphenoid sinus metastasis, 14 months after total abdominal hysterectomy and bilateral salpingo-oophorectomy due to an ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Ilvan S,Akyildiz EU,Calay Z,Celikoyar M,Sahinler I

    更新日期:2004-07-01 00:00:00

  • Phase 2 trial of carboplatin plus tamoxifen in platinum-resistant ovarian cancer and primary carcinoma of the peritoneum.

    abstract:OBJECTIVES:A previously reported phase 2 trial suggested substantial clinical activity associated with the combination of a platinum agent and tamoxifen in the treatment of platinum-resistant ovarian cancer. We wished to confirm or refute this observation in a patient population with well-characterized platinum-resista...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Markman M,Webster K,Zanotti K,Peterson G,Kulp B,Belinson J

    更新日期:2004-08-01 00:00:00

  • Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells.

    abstract:OBJECTIVE:Collagen gel constitutes a valuable tool for the study of cell-matrix interactions; however, it is sometimes difficult to use the gel, in which tumor and stromal cells are cocultured, for immunohistochemistry, because it is easily broken during the process of fixation and embedding in paraffin, especially aft...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Tanaka R,Saito T,Ashihara K,Nishimura M,Mizumoto H,Kudo R

    更新日期:2003-08-01 00:00:00

  • Efficacy of acupuncture in prevention of delayed chemotherapy induced nausea and vomiting in gynecologic cancer patients.

    abstract:OBJECTIVE:To compare the efficacy between acupuncture and ondansetron in the prevention of delayed chemotherapy induced nausea and vomiting (CINV). METHODS:70 patients were randomized to receive either 1) acupuncture at P6 point before chemotherapy infusion or 2) ondansetron 8 mg intravenously 30 min before chemothera...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,随机对照试验


    authors: Rithirangsriroj K,Manchana T,Akkayagorn L

    更新日期:2015-01-01 00:00:00

  • Herpes gestationis may present itself as a paraneoplastic syndrome of choriocarcinoma-a case report.

    abstract:BACKGROUND:Herpes gestationis (HG) is a rare, recurrent, pruritic, vesicobullous dermatosis occurring predominantly in pregnancy and seldom in early puerperium. Reports of the association of HG with choriocarcinoma are extremely rare and this case highlights such a possible link. CASE:This case focuses on the late pos...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Djahansouzi S,Nestle-Kraemling C,Dall P,Bender HG,Hanstein B

    更新日期:2003-05-01 00:00:00

  • Plasmin modulators, aprotinin and anti-catalytic plasmin antibody, efficiently inhibit destruction of bovine vascular endothelial cells by choriocarcinoma cells.

    abstract::The interaction of human gestational choriocarcinoma cell line, SMT-cc1, with bovine vascular endothelial cells, CPAE, was examined in an in vitro coculture model. SMT-cc1 cells have urokinase-type plasminogen activator (uPA) on their cell surface, and more than half of the cell-associated uPA is enzymatically inactiv...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Sugimura M,Kobayashi H,Terao T

    更新日期:1994-03-01 00:00:00

  • Brain metastasis in epithelial ovarian cancer by BRCA1/2 mutation status.

    abstract:OBJECTIVE:To evaluate clinical outcomes of patients with BRCA-associated ovarian cancer who developed brain metastases (BM). METHODS:Patients with epithelial ovarian, fallopian tube, and primary peritoneal cancer (EOC) and BM, treated at a single institution from 1/1/2008-7/1/2018, were identified from two institution...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Stasenko M,Cybulska P,Feit N,Makker V,Konner J,O'Cearbhaill RE,Alektiar KM,Beal K,Gardner GJ,Long Roche KC,Sonoda Y,Chi DS,Zivanovic O,Leitao MM Jr,Cadoo KA,Tew WP

    更新日期:2019-07-01 00:00:00

  • The timing of normalization of CA-125 levels during primary chemotherapy is predictive of survival in patients with epithelial ovarian cancer.

    abstract:OBJECTIVE:To determine if the timing of normalization of CA-125 levels during primary chemotherapy for epithelial ovarian cancer (EOC) could predict survival. METHODS:Patients who reached a complete clinical response for EOC with primary taxane/platinum-based chemotherapy were eligible. Patient demographics, chemother...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rocconi RP,Matthews KS,Kemper MK,Hoskins KE,Huh WK,Straughn JM Jr

    更新日期:2009-08-01 00:00:00

  • Phase II study of vinorelbine in the treatment of platinum-resistant ovarian carcinoma.

    abstract:OBJECTIVE:The purpose of this phase II study was to evaluate on an intent-to-treat basis the activity and toxicity of single-agent vinorelbine (VRL) as second-line chemotherapy of patients with platinum-resistant ovarian cancer. Platinum-resistant disease was defined as disease refractory to or relapsing within 12 mont...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Sørensen P,Høyer M,Jakobsen A,Malmström H,Havsteen H,Bertelsen K

    更新日期:2001-04-01 00:00:00

  • Class II radical hysterectomy shows less morbidity and good treatment efficacy compared to class III.

    abstract::Treatment of 102 patients with cancer of the cervix by class II and III radical hysterectomy was reviewed to compare the operative morbidity and efficacy of class II radical hysterectomy for select cases. Of the 102 patients, 21 had a class II hysterectomy, whereas 81 patients had a class III hysterectomy. The class I...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Photopulos GJ,Zwaag RV

    更新日期:1991-01-01 00:00:00

  • The effect of obesity on survival in patients with ovarian cancer.

    abstract:OBJECTIVE:Data has suggested obesity as an independent prognostic factor for lower survival in patients with epithelial ovarian cancer (EOC). We sought to determine if obesity portends a disadvantage to surgical outcomes at the time of initial surgery affecting survival. METHODS:A retrospective chart review of patient...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Matthews KS,Straughn JM Jr,Kemper MK,Hoskins KE,Wang W,Rocconi RP

    更新日期:2009-02-01 00:00:00

  • Intraperitoneal catheter outcomes in a phase III trial of intravenous versus intraperitoneal chemotherapy in optimal stage III ovarian and primary peritoneal cancer: a Gynecologic Oncology Group Study.

    abstract:OBJECTIVES:To evaluate reasons for discontinuing intraperitoneal (IP) chemotherapy, and to compare characteristics of patients who did versus did not successfully complete six cycles of IP chemotherapy. METHODS:In a phase III trial, women with optimal stage III ovarian or peritoneal carcinoma were randomly allocated t...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Walker JL,Armstrong DK,Huang HQ,Fowler J,Webster K,Burger RA,Clarke-Pearson D

    更新日期:2006-01-01 00:00:00

  • Prognostic factors for groin node metastasis in squamous cell carcinoma of the vulva (a Gynecologic Oncology Group study)

    abstract::From 1977 to 1984 the Gynecologic Oncology Group (GOG) conducted a prospective clinical and surgical staging protocol of squamous cell carcinoma of the vulva (n = 637). The patients with superficial (5 mm or less invasion) lesions were the subject of a previous report (n = 272). The subject of this report is on factor...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Homesley HD,Bundy BN,Sedlis A,Yordan E,Berek JS,Jahshan A,Mortel R

    更新日期:1993-06-01 00:00:00

  • Evaluation of deletions in 7q11.2 and 8p12-p21 as prognostic indicators of tumour development following molar pregnancy.

    abstract:OBJECTIVES:Previous studies have identified loss of chromosomal regions 7p12-q11.2 and 8p12-p21 in choriocarcinoma suggesting that suppressor genes involved in tumour development may be located within these regions. Our objectives were to refine the regions of loss and evaluate these deletions as prognostic indicators ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Burke B,Sebire NJ,Moss J,Hodges MD,Seckl MJ,Newlands ES,Fisher RA

    更新日期:2006-11-01 00:00:00

  • Trends in guideline-adherent fertility-sparing surgery for early-stage cervical cancer before and after the Affordable Care Act.

    abstract:OBJECTIVE:To assess trends in guideline-adherent fertility-sparing surgery (GA-FSS) for early-stage cervical cancer relative to Patient Protection and Affordable Care Act (ACA) implementation. METHODS:National Cancer Database patients treated for Stage IA1-IB1 cervical cancer from 2004 to 2016 were included. Multivari...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Sutaria T,Sparks AD,Rao YJ,Lopez-Acevedo M,Long B

    更新日期:2020-08-01 00:00:00

  • Outcome of investigations for postmenopausal vaginal bleeding in women under the age of 50 years.

    abstract:OBJECTIVE:The objective of this study is to determine the incidence of endometrial cancer in young postmenopausal women presenting with vaginal bleeding. METHODS:Cross-sectional study of postmenopausal women presenting with vaginal bleeding in a gynaecological oncology centre in the United Kingdom. All women underwent...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Burbos N,Musonda P,Crocker SG,Morris EP,Duncan TJ,Nieto JJ

    更新日期:2012-04-01 00:00:00

  • Therapy-related myeloid leukemia after treatment for epithelial ovarian carcinoma: an epidemiological analysis.

    abstract:OBJECTIVE:Therapy related acute myeloid leukemia (t-AML) is a potential late complication of cytotoxic therapy, and it is of particular concern in the treatment of patients with epithelial ovarian carcinoma (EOC) exposed to multiple courses of chemotherapy during the course of their disease. This study examines the inc...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Vay A,Kumar S,Seward S,Semaan A,Schiffer CA,Munkarah AR,Morris RT

    更新日期:2011-12-01 00:00:00

  • The significance of cone biopsy resection margins.

    abstract::This 12-year retrospective study examines the significance of margin involvement with dysplasia at cone biopsy in relation to follow-up. Of 300 cone biopsies, 123 (41%) had margin involvement. These cases of margin involvement were associated with more severe dysplasia (P less than 0.0001) and a higher chance of subse...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Paterson-Brown S,Chappatte OA,Clark SK,Wright A,Maxwell P,Taub NA,Raju KS

    更新日期:1992-08-01 00:00:00