当前位置： SCI文献检索 > GYNECOLOGIC ONCOLOGY期刊下所有文献 > Extra-peritoneal laparoscopic para-aortic lymphadenectomy--a prospective cohort study of 293 patients with endometrial cancer.

Extra-peritoneal laparoscopic para-aortic lymphadenectomy--a prospective cohort study of 293 patients with endometrial cancer.

Abstract：

OBJECTIVE:To determine if extra-peritoneal laparoscopic para-aortic (PA) lymphadenectomy allows a reliable assessment of PA nodes in patients with endometrial cancer (EC). METHODS:In October of 2005, a single surgeon began performing extra-peritoneal laparoscopic PA lymphadenectomy for patients with EC. A prospective cohort study was initiated from October 2005 through October 2007. Staging of Group A included extra-peritoneal laparoscopic PA lymphadenectomy, while Group B underwent staging via laparotomy. RESULTS:In a 24 month period, 293 patients underwent surgical treatment for EC, 203 of them underwent complete staging as determined by previously published criteria. Extra-peritoneal laparoscopic PA lymphadenectomy to the renal veins was successful in 35/38 patients (92%). Mean BMI was 33.0 for Group A and 32.3 for Group B (p=NS). Mean EBL and hospital stay were lower in Group A compared to Group B (163 vs 373 cm(3), p<0.0001; median 2 vs 4 nights, p<0.001). The total number of PA nodes harvested was not statistically different between Groups A and B (16.5 vs 19.6). Interestingly, in Group A the total number of PA nodes was greater for patients with BMI>35, (21.6 vs 13.1), while in Group B fewer nodes were removed in obese patients (17.8 vs 20.5). CONCLUSIONS:Extra-peritoneal laparoscopy is a reliable method to routinely reach the level of the renal veins, even in obese patients. This approach was feasible in over 90% of unselected patients and well-tolerated.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Dowdy SC,Aletti G,Cliby WA,Podratz KC,Mariani A

doi

10.1016/j.ygyno.2008.08.021

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

418-24

issue

3

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(08)00669-0

journal_volume

111

pub_type

杂志文章

相关文献

GYNECOLOGIC ONCOLOGY文献大全
  • Sentinel node mapping vs. lymphadenectomy in endometrial cancer: A systematic review and meta-analysis.

    abstract：:Sentinel node mapping is increasingly being utilized for endometrial cancer staging. However, only limited evidence supporting the adoption of sentinel node mapping instead of conventional lymphadenectomy is still available. Here, we aimed to review the current evidence comparing sentinel node mapping and lymphadenect...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.ygyno.2019.03.254

    authors： Bogani G,Murgia F,Ditto A,Raspagliesi F

    更新日期：2019-06-01 00:00:00

  • Cytokeratin staining of resected lymph nodes may improve the sensitivity of surgical staging for endometrial cancer.

    abstract：OBJECTIVE:The presence of metastases to regional lymph nodes (LN) is the single most important risk factor in endometrial cancer. Advances in molecular biology have provided more sensitive methods for detecting micrometastasis. This was a pilot study to determine whether cytokeratin staining of LN from endometrial canc...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2003.08.026

    authors： Gonzalez Bosquet J,Keeney GL,Mariani A,Webb MJ,Cliby WA

    更新日期：2003-12-01 00:00:00

  • Prognostic factors for early-stage epithelial ovarian cancer, treated with adjuvant carboplatin/paclitaxel chemotherapy: a single institution experience.

    abstract：OBJECTIVE:Early-stage epithelial ovarian cancer represents a prognostically heterogenous group. We studied prognostic factors in patients treated with adjuvant paclitaxel/carboplatin chemotherapy. METHODS:Data was extracted from 147 patients with FIGO stage IA/IB, grade 2/3 or stage IC/IIA (any grade) who underwent pr...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2011.06.033

    authors： Bamias A,Karadimou A,Soupos N,Sotiropoulou M,Zagouri F,Haidopoulos D,Thomakos N,Rodolakis A,Antsaklis A,Dimopoulos MA

    更新日期：2011-10-01 00:00:00

  • The use of CT findings to predict extent of tumor at primary surgery for ovarian cancer.

    abstract：BACKGROUND:High tumor dissemination (HTD) is a major risk factor for serious morbidity after primary ovarian cancer (OC) surgery, particularly in medically compromised patients. We performed a pilot study of whether CT findings could predict extent of disease and surgical complexity necessary in advanced OC. METHODS:P...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2013.05.007

    authors： Glaser G,Torres M,Kim B,Aletti G,Weaver A,Mariani A,Hartmann L,Cliby W

    更新日期：2013-08-01 00:00:00

  • Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk.

    abstract：OBJECTIVES:MDM2 is an important negative regulator of the p53 tumor suppressor protein. A naturally occurring T/G single nucleotide polymorphism (SNP) in the MDM2 gene promoter, SNP309, causes an increase in MDM2 protein levels and impairment of p53 tumor suppressor activity. SNP309 occurs at a relatively high frequenc...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2006.10.008

    authors： Walsh CS,Miller CW,Karlan BY,Koeffler HP

    更新日期：2007-03-01 00:00:00

  • Combined methotrexate-dactinomycin: an effective therapy for low-risk gestational trophoblastic neoplasia.

    abstract：OBJECTIVE:The objective of this study is to examine the outcomes of combined chemotherapy using methotrexate and dactinomycin in the management of women with low-risk gestational trophoblastic neoplasia (GTN). The primary outcome is the total number of cycles of chemotherapy required to achieve a normal level of human ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2011.10.036

    authors： Eiriksson L,Wells T,Steed H,Schepansky A,Capstick V,Hoskins P,Pike J,Swenerton K

    更新日期：2012-03-01 00:00:00

  • Evaluation of the scalene lymph nodes in primary and recurrent cervical carcinoma.

    abstract：:Open biopsy of the left scalene lymph nodes has been utilized to identify distant spread of cervical carcinoma in selected groups of patients who do not have other clinical evidence of disseminated disease. Twenty-one patients with primary cervical carcinoma and histologically proven para-aortic lymph node metastases ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(87)90178-8

    authors： Burke TW,Heller PB,Hoskins WJ,Weiser EB,Nash JD,Park RC

    更新日期：1987-11-01 00:00:00

  • Feasibility study comparing docetaxel-cisplatin versus docetaxel-carboplatin as first-line chemotherapy for ovarian cancer.

    abstract：OBJECTIVE:To determine the feasibility of docetaxel-cisplatin combination therapy compared with docetaxel-carboplatin combination therapy as first-line chemotherapy for patients with ovarian cancer. METHODS:Fifty patients with International Federation of Gynecology and Obstetrics stage Ic-IV ovarian cancer who underwe...

    journal_title：Gynecologic oncology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.ygyno.2005.11.020

    authors： Minagawa Y,Kigawa J,Kanamori Y,Itamochi H,Terakawa N,Okada M,Kitada F

    更新日期：2006-06-01 00:00:00

  • Is aspirin use associated with a decreased risk of ovarian cancer? A systematic review and meta-analysis of observational studies with dose-response analysis.

    abstract：OBJECTIVE:Currently available epidemiologic evidences concerning the chemopreventive effect of aspirin on ovarian cancer are inconsistent. Therefore, we aimed to further explore the association by synthesizing evidence from population-based studies. METHODS:We searched PubMed, EMBASE, Web of Science, and Scopus using ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.ygyno.2016.04.543

    authors： Zhang D,Bai B,Xi Y,Wang T,Zhao Y

    更新日期：2016-08-01 00:00:00

  • Relationship between a history of systemic allergic reactions and risk of subsequent carboplatin hypersensitivity.

    abstract：OBJECTIVE:The establishment of clinical features identifying patients at a heightened risk for the development of carboplatin hypersensitivity may assist in the management of this important toxicity. Based on a previous report suggesting a history of "bee sting" allergy predicted for paclitaxel hypersensitivity, we att...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/s0090-8258(03)00155-0

    authors： Markman M,Zanotti K,Kulp B,Peterson G,Markman M

    更新日期：2003-06-01 00:00:00

  • The effect of diabetes and metformin on clinical outcomes is negligible in risk-adjusted endometrial cancer cohorts.

    abstract：OBJECTIVE:To examine the influence of diabetes and metformin therapy on overall survival (OS) and progression-free survival (PFS) in patients with endometrial cancer (EC) by using propensity score (PS) matching to account for confounding factors. METHODS:We retrospectively identified consecutive patients with stage I-...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2015.11.019

    authors： Al Hilli MM,Bakkum-Gamez JN,Mariani A,Cliby WA,Mc Gree ME,Weaver AL,Dowdy SC,Podratz KC

    更新日期：2016-02-01 00:00:00

  • Molecular evidence linking primary cancer of the fallopian tube to BRCA1 germline mutations.

    abstract：OBJECTIVES:BRCA1 and BRCA2 germline mutations increase the risk of ovarian and breast cancer. Fallopian tube cancer has occasionally been observed in breast-ovarian cancer families. At our family cancer clinic we recently encountered two cases of Fallopian tube cancer within two families harboring a BRCA1 germline muta...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1999.5623

    authors： Zweemer RP,van Diest PJ,Verheijen RH,Ryan A,Gille JJ,Sijmons RH,Jacobs IJ,Menko FH,Kenemans P

    更新日期：2000-01-01 00:00:00

  • Preferences for surveillance strategies for women treated for high-grade precancerous cervical lesions.

    abstract：OBJECTIVES:Data are lacking on how women view alternative approaches to surveillance for cervical cancer after treatment of high-grade cervical intraepithelial neoplasia. We measured and compared patient preferences (utilities) for scenarios with varying surveillance strategies and outcomes to inform guidelines and cos...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2010.05.002

    authors： Kuppermann M,Melnikow J,Slee C,Tancredi DJ,Kulasingam S,Birch S,Helms LJ,Bayoumi AM,Sawaya GF

    更新日期：2010-08-01 00:00:00

  • Comparison of secondary and primary ovarian malignancies reveals differences in their pre- and perioperative characteristics.

    abstract：OBJECTIVE:Preoperative differentiation of primary and metastatic ovarian tumors is difficult. Young age of the patient, bilateralism and reduced multilocularity are cited characteristics of secondary ovarian malignancies. We sought to identity pre- and perioperative factors which may aid in differentiating metastatic o...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2005.09.046

    authors： Antila R,Jalkanen J,Heikinheimo O

    更新日期：2006-04-01 00:00:00

  • Intermediate-term results of trans-abdominal ultrasound (TAUS)-guided brachytherapy in cervical cancer.

    abstract：OBJECTIVES:To report the intermediate-term results of trans-abdominal ultrasound (TAUS)-guided brachytherapy in cervical cancer. MATERIALS AND METHODS:Ninety-two patients with cervical cancer (stage IB-IVA, according to FIGO staging), were treated by curative radiotherapy from February 2012 to June 2015. All patients ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2018.01.015

    authors： Tharavichitkul E,Chakrabandhu S,Klunklin P,Onchan W,Jia-Mahasap B,Wanwilairat S,Tippanya D,Jayasvasti R,Sripan P,Galalae RM,Chitapanarux I

    更新日期：2018-03-01 00:00:00

  • Neoadjuvant chemotherapy and chemotherapy cycle number: A national multicentre study.

    abstract：OBJECTIVES:Six cycles of consolidation chemotherapy have become the standard for ovarian cancer treatment regimen following primary cytoreduction, yet with neoadjuvant chemotherapy (NAC), only 3 consolidation cycles are used. This study examines the effects of number of chemotherapy cycles in women with ovarian cancer ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ygyno.2017.08.006

    authors： Altman AD,McGee J,May T,Lane K,Lu L,Xu W,Ghatage P,Rosen B

    更新日期：2017-11-01 00:00:00

  • POSTN/TGFBI-associated stromal signature predicts poor prognosis in serous epithelial ovarian cancer.

    abstract：OBJECTIVE:To identify molecular prognosticators and therapeutic targets for high-grade serous epithelial ovarian cancers (EOCs) using genetic analyses driven by biologic features of EOC pathogenesis. METHODS:Ovarian tissue samples (n = 172; 122 serous EOCs, 30 other EOCs, 20 normal/benign) collected prospectively from...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2013.12.021

    authors： Karlan BY,Dering J,Walsh C,Orsulic S,Lester J,Anderson LA,Ginther CL,Fejzo M,Slamon D

    更新日期：2014-02-01 00:00:00

  • Low-grade serous carcinoma: new concepts and emerging therapies.

    abstract：:For the past several years, all women with epithelial ovarian cancer have been treated identically, whether in a clinical trial or off protocol. Over the past decade, we have come to appreciate the magnitude of the heterogeneity of ovarian cancer. The development of the binary grading system for serous carcinoma was a...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ygyno.2013.05.021

    authors： Romero I,Sun CC,Wong KK,Bast RC Jr,Gershenson DM

    更新日期：2013-09-01 00:00:00

  • An immunohistochemical study of colon-ovarian tumor antigen and colon-specific antigen in gynecologic tumors.

    abstract：:The distribution of colon--ovarian tumor antigen (COTA) and colon-specific antigen (CSA) was studied immunohistochemically in gynecologic tumors. The antigens were absent in the serous benign tumors of the ovary and in the normal ovarian tissues, whereas they were detected in some of the mucinous benign tumors. COTA a...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(89)90019-x

    authors： Ueda G,Shimizu C,Saito J,Tanaka Y,Inoue M,Tanizawa O

    更新日期：1989-10-01 00:00:00

  • Minimal change disease in a patient with ovarian papillary serous carcinoma.

    abstract：BACKGROUND:Nephrotic syndrome (NS) is rarely associated with ovarian tumor. Only five cases of NS with pathologic diagnosis have been reported in patients with ovarian tumors. However, the association between minimal change disease (MCD) and ovarian tumor has not been previously reported. CASE:A 55-year-old woman pres...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2004.02.022

    authors： Ryu DR,Yoo TH,Kim YT,Jeong HJ,Cho NH,Kang SW

    更新日期：2004-05-01 00:00:00

  • A population-based study of causes of death after endometrial cancer according to major risk factors.

    abstract：OBJECTIVE:To identify the most common causes of death and potentially modifiable risk factors in endometrial cancer patients. METHODS:745 women diagnosed with incident endometrial cancer were enrolled in a population-based study from 1991 to 1994. Participants completed structured interviews about 1 year after diagnos...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2020.12.020

    authors： Lees B,Hampton JM,Trentham-Dietz A,Newcomb P,Spencer R

    更新日期：2021-01-06 00:00:00

  • Adjunctive hysterectomy following radiation therapy for bulky carcinoma of the uterine cervix: prognostic implications of tumor persistence.

    abstract：:Twenty-five patients underwent adjunctive extrafascial hysterectomy 14-60 days following completion of external and intracavitary irradiation for bulky carcinoma of the uterine cervix. Review of the operative histopathology and correlation with subsequent patient outcomes suggests that morphologically persistent cance...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(87)90217-4

    authors： Russell AH,Burt AR,Ek M,Russell KJ,Cain JM,Greer BE,Tamimi HK,Figge DC

    更新日期：1987-10-01 00:00:00

  • Simple extrafascial trachelectomy and pelvic bilateral lymphadenectomy in early stage cervical cancer.

    abstract：OBJECTIVE:To determine the feasibility and safety of simple extra-fascial trachelectomy plus pelvic lymphadenectomy in young patients affected by early stage cervical cancer. METHODS:We have prospectively identified all patients with early-stage cervical cancer (stages IA2-IB1) referred to our department. Inclusion cr...

    journal_title：Gynecologic oncology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ygyno.2012.04.004

    authors： Palaia I,Musella A,Bellati F,Marchetti C,Di Donato V,Perniola G,Benedetti Panici P

    更新日期：2012-07-01 00:00:00

  • A pilot study of intra-arterial carboplatin in patients with recurrent carcinoma of the cervix, postradiation.

    abstract：:Twelve patients with recurrent squamous cell carcinoma of the cervix restricted to the pelvis were treated with intra-arterial infusion of carboplatin. The initial carboplatin dose was 300 mg/m2, every 4 weeks, and the dose was escalated to 450 mg/m2. Myelosuppression was the dose-limiting toxicity at the 450 mg/m2 do...

    journal_title：Gynecologic oncology

    pub_type： 临床试验,杂志文章

    doi：10.1006/gyno.1994.1136

    authors： Verma S,Prefontaine M,Bertrand M,Genest P,Dahrouge S

    更新日期：1994-06-01 00:00:00

  • Studies on the distribution of abnormal cells in cytological smears. VII. Cervical brush versus plastic and wooden spatulas.

    abstract：:A model system of exfoliated normal human cervicovaginal squamous cells, exfoliated rodent tumor cells, and acellular, viscous, mucuslike material was used to investigate cell deposition on smear preparations made with three different instruments: plastic spatulas, wooden spatulas, and brush-tipped collectors. The tot...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(90)90426-l

    authors： Rubio CA,Kock Y,Stormby N,Porwit A

    更新日期：1990-11-01 00:00:00

  • Increased frequency of complete hydatidiform mole in women with repeated abortion.

    abstract：:The association between spontaneous abortion and gestational trophoblastic disease (GTD) has been investigated in a study based on 93 women with 2 consecutive (repeated) spontaneous abortions and 82 control subjects who delivered normal babies. Nine molar pregnancies were observed among 7 of the 93 cases of repeated a...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/s0090-8258(88)80009-x

    authors： Acaia B,Parazzini F,La Vecchia C,Ricciardiello O,Fedele L,Battista Candiani G

    更新日期：1988-10-01 00:00:00

  • Radical vaginal trachelectomy after supracervical hysterectomy.

    abstract：BACKGROUND:Radical vaginal trachelectomy (RVT) is an acceptable approach when applied toward a select group of patients with early stage cervical carcinoma. It is less invasive, can maintain fertility, and can be ideal in patients with significant comorbid factors compared to abdominal approaches. A small subset of pat...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.2002.6660

    authors： Mendez LE,Penalver M,McCreath W,Bejarano P,Angioli R

    更新日期：2002-06-01 00:00:00

  • CDK7 is a reliable prognostic factor and novel therapeutic target in epithelial ovarian cancer.

    abstract：OBJECTIVE:Cyclin-dependent kinase 7 (CDK7) engages tumor growth by acting as a direct link between the regulation of transcription and the cell cycle. Here, we investigated the clinical significance of CDK7 expression and its potential as a therapeutic target in epithelial ovarian cancer (EOC). METHODS:CDK7 expression...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2019.11.004

    authors： Kim J,Cho YJ,Ryu JY,Hwang I,Han HD,Ahn HJ,Kim WY,Cho H,Chung JY,Hewitt SM,Kim JH,Kim BG,Bae DS,Choi CH,Lee JW

    更新日期：2020-01-01 00:00:00

  • Gonadotropin stimulation of MLS human epithelial ovarian carcinoma cells augments cell adhesion mediated by CD44 and by alpha(v)-integrin.

    abstract：OBJECTIVE:The goal of this work was to evaluate the involvement of gonadotropins in the regulation of adhesion of human epithelial ovarian carcinoma. We studied two pathways that were previously implicated in the metastatic implantation of ovarian carcinoma to the peritoneum, namely hyaluronan-CD44 and RGD-integrin med...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.2001.6512

    authors： Schiffenbauer YS,Meir G,Maoz M,Even-Ram SC,Bar-Shavit R,Neeman M

    更新日期：2002-02-01 00:00:00

  • Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapy.

    abstract：:Fifty-one patients with advanced ovarian cancer FIGO III were studied to determine new tumor biology-oriented prognostic factors. The tumor-associated protease urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 were detected in malignant ovarian cancer tissue extracts. The concentration of both factors...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1994.1313

    authors： Kuhn W,Pache L,Schmalfeldt B,Dettmar P,Schmitt M,Jänicke F,Graeff H

    更新日期：1994-12-01 00:00:00