Combined living donor liver/small bowel transplantation.

abstract：BACKGROUND:Steroid-resistant acute rejection is a risk factor for inferior renal allograft outcome. METHODS:From 873 kidney transplant recipients (1995-2005), 108 patients with a first rejection episode were selected for study using strict inclusion criteria and clinical endpoint definition. We aimed to predict respon...

journal_title：Transplantation

authors： Rekers NV,Bajema IM,Mallat MJ,Zuidwijk K,Anholts JD,Goemaere N,Haasnoot GW,van Groningen MC,van Kooten C,de Fijter JW,Claas FH,Eikmans M

更新日期：2012-09-27 00:00:00

abstract：:Heterologous anti-immunoglobulin is a potent immunosuppressive agent that prolongs H-2- and H-3-incompatible skin graft survival. In conjunction with antithymocyte serum, anti-immunoglobulin promotes greater graft life than either antiserum used alone, without evidence of toxicity to recipient animals. Combination tre...

journal_title：Transplantation

authors： Constantian MB,Couser WG,Mannick JA

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Posttransplant lymphoproliferative disease (PTLD) after pediatric liver transplantation has been associated with high mortality rates. METHODS:The present study examined 282 consecutive pediatric liver transplant recipients from October 1989 to June 1996 who received primary tacrolimus immunosuppression. Th...

journal_title：Transplantation

authors： Cacciarelli TV,Green M,Jaffe R,Mazariegos GV,Jain A,Fung JJ,Reyes J

更新日期：1998-10-27 00:00:00

abstract：BACKGROUND:The deceased donor score (DDS), expanded criteria donor (ECD) definition, and resistive index (RI) were developed for pretransplant evaluation of donors. DDS and ECD are determined by a calculation of risk from donor variables, while RI is determined from flow characteristics of kidneys during machine preser...

journal_title：Transplantation

authors： Nyberg SL,Baskin-Bey ES,Kremers W,Prieto M,Henry ML,Stegall MD

更新日期：2005-10-15 00:00:00

abstract：:There is considerable current interest in the possibility that long-term graft acceptance in clinical solid-organ transplantation might be dependent upon the development of a microchimeric state between the donor and recipient. This possibility has been prompted by the observation that in some transplant patients cell...

journal_title：Transplantation

authors： Bushell A,Pearson TC,Morris PJ,Wood KJ

更新日期：1995-05-27 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is common in kidney transplantation and is known to affect long-term patient and graft survival, as is time in renal-replacement therapy (RRT). The aim of this study was to investigate HCV in relation to time in RRT and its impact on outcome after transplantation. METHODS:A...

journal_title：Transplantation

authors： Bruchfeld A,Wilczek H,Elinder CG

更新日期：2004-09-15 00:00:00

abstract：BACKGROUND:The role of changes in peri-operative blood lactate levels in recipients of living-related liver transplants has not yet been clarified. METHODS:Forty-three recipients were included in this study. Blood lactate, plasma total bilirubin, aminotransferase, body temperature, and gastric mucosal PCO2 levels were...

journal_title：Transplantation

authors： Orii R,Sugawara Y,Hayashida M,Yamada Y,Kubota K,Takayama T,Harihara Y,Makuuchi M,Hanaoka K

更新日期：2000-05-27 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is a potent endothelial cell growth and permeability factor, expressed in the lung. Overexpression of VEGF is associated with increased vascular permeability in the early stage of acute lung injury in mice. The role of various forms of VEGF in transplantation-induced...

journal_title：Transplantation

authors： Abraham D,Taghavi S,Riml P,Paulus P,Hofmann M,Baumann C,Kocher A,Klepetko W,Aharinejad S

更新日期：2002-06-15 00:00:00

abstract：BACKGROUND:Currently, many transplantation centers do not follow former living kidney donors on a long-term basis. Several potential barriers have been identified to provide this follow-up of former living kidney donors, including concerns that donor insurance will not reimburse transplantation centers or primary care ...

journal_title：Transplantation

authors： Kher A,Rodrigue J,Ajaimy M,Wasilewski M,Ladin K,Mandelbrot D

更新日期：2012-11-27 00:00:00

abstract：:The expression of some genes has been comparatively studied in transplanted rat liver and in liver reperfused after ischemia in situ. Experiments on protein synthesis by tissue slices from cold-stored or transplanted livers show that rat livers that retain a good capacity for protein synthesis during storage undergo a...

journal_title：Transplantation

authors： Schiaffonati L,Cairo G,Tacchini L,Pappalardo C,Gatti S,Piazzini-Albani A,Bernelli-Zazzera A

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Endomyocardial biopsy (EMB) remains the gold standard for acute cellular rejection (ACR) diagnosis in cardiac transplantation yet is subject to interobserver variability. A method that could avoid discordant EMB analysis would be desirable. The apoptosis rate in EMB correlates with ACR severity. Apollon inhi...

journal_title：Transplantation

authors： Aharinejad S,Andrukhova O,Gmeiner M,Thomas A,Krenn K,Zuckermann A,Grimm M

更新日期：2010-01-27 00:00:00

abstract：BACKGROUND:Current immunosuppression regimens are toxic to transplant recipients and, in many cases, acute rejection episodes occur because of escape of donor-reactive lymphocytes from the immunosuppression. T cells are the mediators of acute, cell-mediated graft damage and are hypothesized to use the CXCR3 chemokine a...

journal_title：Transplantation

authors： Rosenblum JM,Zhang QW,Siu G,Collins TL,Sullivan T,Dairaghi DJ,Medina JC,Fairchild RL

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND:Knowledge on the reinnervation of transplanted organs is scarce, and the aim of the study was therefore to evaluate to what degree syngeneic pancreas grafts were reinnervated in rats. METHODS:Syngeneic pancreatico-duodenal transplantations were performed in normoglycemic Wistar-Furth rats. Native and transp...

journal_title：Transplantation

authors： Korsgren O,Jansson L,Ekblad E,Sundler F

更新日期：2001-01-15 00:00:00

abstract：:Healthy rat islets were encapsulated in alginate-polylysine-alginate capsules measuring 0.25-0.35 mm in diameter using a modified encapsulation technique. The encapsulated islets were transplanted intraperitoneally in nonimmunosuppressed streptozotocin-induced diabetic BALB/c mice. The diabetic condition of the experi...

journal_title：Transplantation

authors： Lum ZP,Krestow M,Tai IT,Vacek I,Sun AM

更新日期：1992-06-01 00:00:00

abstract：:The humanization of animals is a powerful tool for the exploration of human disease pathogenesis in biomedical research, as well as for the development of therapeutic interventions with enhanced translational potential. Humanized models enable us to overcome biologic differences that exist between humans and other spe...

journal_title：Transplantation

authors： Adigbli G,Ménoret S,Cross AR,Hester J,Issa F,Anegon I

更新日期：2020-11-01 00:00:00

abstract：:Suspensions of viable lymph node cells (LNCs), both unlabeled and 3H-uridine labeled, from adult Fischer (FI) rats were inoculated into the lumens of established, surgically isolated segments of ileum in adult (FI x DA)F1 hybrid hosts. Vascular, lymphatic, and nerve supplies of the isolated segment were preserved. It ...

journal_title：Transplantation

authors： Seelig LL Jr,Billingham RE

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:According to a pooled analysis of three randomized clinical studies concerning the prevention of acute rejection in cadaveric renal transplantation, mycophenolate mofetil (MMF) proved superior to azathioprine or placebo in conjunction with cyclosporine (CsA) and steroids. MMF-treated patients showed reduced ...

journal_title：Transplantation

authors： Kim YS,Moon JI,Kim SI,Park K

更新日期：1999-08-27 00:00:00

abstract：:Pre-existing alloantibodies against the mismatched HLA-A and HLA-B antigens of the donor, when present in current sera, are believed to be detrimental to kidney graft survival. When these antibodies are present only in historical sera, their immunoglobulin class has reported to be important with respect to the expecte...

journal_title：Transplantation

authors： Roelen DL,van Bree J,Witvliet MD,Habraken I,van Beelen E,van't Sant PH,de Waal LP,van Rood JJ,Claas FH

更新日期：1994-05-15 00:00:00

abstract：:Chronic hepatitis C is a common cause of viral liver disease in kidney transplant (KT) recipients. To assess the efficacy and safety of therapy with interferon alpha we conducted a prospective study where 14 cadaveric KT recipients with chronic hepatitis C received recombinant interferon alpha-2b (IFNa) 3 million unit...

journal_title：Transplantation

authors： Rostaing L,Izopet J,Baron E,Duffaut M,Puel J,Durand D

更新日期：1995-05-27 00:00:00

abstract：:Feline bone marrow cells treated with the soybean agglutinin (SBA) lectin are separated into two populations, the agglutinated SBA(+) fraction containing predominantly cells of myeloid origin and the nonagglutinated SBA(-) fraction consisting of cells primarily of the erythroid lineage. FACScan analyses revealed a cle...

journal_title：Transplantation

authors： Gengozian N,Reyes L,Pu R,Homer BL,Bova FJ,Yamamoto JK

更新日期：1997-08-15 00:00:00

abstract：:Acute murine cytomegalovirus (MCMV) infection enhances the ability of parental spleen cells to induce graft-vs.-host immunodeficiency (GVHID) in F1 hybrid mice when the two processes occur simultaneously in the recipient. The present study assessed GVHID as the ability of spleen cells to generate in vitro cytotoxic T ...

journal_title：Transplantation

authors： Via CS,Shanley JD,Weatherly BR,Lang P,Shearer GM

更新日期：1988-08-01 00:00:00

abstract：:FK506, an immunosuppresant, was isolated from Streptomyces tsukubaensis. Intramuscular administration of FK506 (0.32 mg/kg or more) 5 days a week for two weeks after grafting prolonged the acceptance time of F344 skin allograft to WKA rats. Similar results were obtained with cyclosporine at 32 mg/kg or more, but other...

journal_title：Transplantation

authors： Inamura N,Nakahara K,Kino T,Goto T,Aoki H,Yamaguchi I,Kohsaka M,Ochiai T

更新日期：1988-01-01 00:00:00

abstract：:Preventing hyperacute rejection (HAR) is a difficult and unsolved problem in xenotransplantation. This may be due, in part, to a lack of therapies that can suppress production of natural antibodies (NA), which are thought to be critical mediators of HAR. This study examined the effect of 15-deoxyspergualin (DSPG) and ...

journal_title：Transplantation

authors： Leventhal JR,Flores HC,Gruber SA,Figueroa J,Platt JL,Manivel JC,Bach FH,Matas AJ,Bolman RM 3rd

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Nonspecific inflammatory damages occurring prior to organ transplantation reduce long-term graft survival. Here, we tested the beneficial effects of carbon monoxide (CO) induction by methylene chloride (MC). METHODS:Fischer-344 (F-344 Rat) or Dark Agouti (DA Rat) donor animals were either treated with MC fo...

journal_title：Transplantation

authors： Martins PN,Reutzel-Selke A,Jurisch A,Denecke C,Attrot K,Pascher A,Kotsch K,Pratschke J,Neuhaus P,Volk HD,Tullius SG

更新日期：2006-10-15 00:00:00

abstract：BACKGROUND:Few studies have examined the effectiveness of a risk-stratified approach to screening kidney transplantation candidates for ischemic heart disease (IHD). METHODS:We retrospectively reviewed records from all adult patients (n = 514) placed on the deceased donor kidney transplantation waiting list at a singl...

journal_title：Transplantation

authors： Kasiske BL,Malik MA,Herzog CA

更新日期：2005-09-27 00:00:00

abstract：:The protective effect of oxygen free radical scavenger superoxide dismutase (SOD) against the warm ischemic damage that occurs in kidneys harvested from non-heart-beating donors is controversial because of its short half-life. In this model, we compared the protective effect of SOD and two longer lasting polyethylene ...

journal_title：Transplantation

authors： Morpurgo E,Cadrobbi R,Morpurgo M,Rigotti P,Schiavon F,Schiavon O,Caliceti P,Ancona E,Veronese FM

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:This study evaluates whether surgical strategies such as the portosystemic shunt and ischemic preconditioning can protect against hepatic and pulmonary injury associated with liver transplantation. METHODS:The effect of the portosystemic shunt, ischemic preconditioning, and both surgical procedures together...

journal_title：Transplantation

authors： Fernández L,Heredia N,Peralta C,Xaus C,Roselló-Catafau J,Rimola A,Marco A,Serafín A,Deulofeu R,Gelpí E,Grande L

更新日期：2003-07-27 00:00:00

abstract：BACKGROUND:Immunosuppressive regimens for kidney transplantation which reduce the long-term burden of immunosuppression are attractive, but little data are available to judge the safety and efficacy of the different strategies used. We tested the hypothesis that the simple, cheap, regimen of alemtuzumab induction combi...

journal_title：Transplantation

authors： Chan K,Taube D,Roufosse C,Cook T,Brookes P,Goodall D,Galliford J,Cairns T,Dorling A,Duncan N,Hakim N,Palmer A,Papalois V,Warrens AN,Willicombe M,McLean AG

更新日期：2011-10-15 00:00:00

abstract：BACKGROUND:Renal transplant recipients have an increased incidence of cardiovascular disease, but less data exist about cerebrovascular atherosclerosis. In this study, we assessed the prevalence of carotid lesions as evaluated by B-mode ultrasonography in a group of renal transplant recipients, and we evaluated univari...

journal_title：Transplantation

authors： Barbagallo CM,Pinto A,Gallo S,Parrinello G,Caputo F,Sparacino V,Cefalù AB,Novo S,Licata G,Notarbartolo A,Averna MR

更新日期：1999-02-15 00:00:00

abstract：:The mechanism (or mechanisms) underlying the indefinite survival of DBA/2 islet allografts in strongly histoincompatible (C57BL/6xA)F1 (B6AF1) mice, induced either by the combined use of Ficoll-prepared crude islets and treatment of recipients with antilymphocyte serum (ALS), or by the use of handpicked, purified isle...

journal_title：Transplantation

authors： Gotoh M,Porter J,Monaco AP,Maki T

更新日期：1988-02-01 00:00:00