Ten-year follow-up of children born at

Abstract:

BACKGROUND:Thyroid hormones are essential for brain development. We conducted a randomized, controlled trial with thyroxine (T4) supplementation in infants <30 weeks' gestation and with the last neurodevelopmental follow-up moment at the age of 5.5 years. T4 supplementation was associated with improved outcome of infants <28 weeks' gestation and worse outcome of infants of 29 weeks' gestation. We studied gestational age-dependent effects of T4 supplementation at the mean age of 10.5 years in children participating in our randomized, controlled trial. METHODS:Questionnaires regarding school outcome, behavior, quality of life, motor problems, and parental stress were sent to the parents and children and their teachers at the same time point for all surviving children (9-12 years of age). RESULTS:Seventy-two percent of the families responded to our questionnaires. Nonrespondents had more sociodemographic risk factors and worse development until 5.5 years. At the mean age of 10.5 years, T4 supplementation was associated with better school outcome in those who were <27 weeks' gestation and better motor outcome in those who were <28 weeks' gestation, whereas the reverse was true for those who were born at 29 weeks' gestation. No other gestational age-dependent outcomes were found. CONCLUSIONS:Gestation-dependent effects of T4 supplementation remain stable over time. These effects do not prove beneficial effects of T4 in infants <28 weeks but should be the background for a new randomized, controlled trial with thyroid hormone in this age group.

journal_name

Pediatrics

journal_title

Pediatrics

authors

van Wassenaer AG,Westera J,Houtzager BA,Kok JH

doi

10.1542/peds.2005-0876

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

e613-8

issue

5

eissn

0031-4005

issn

1098-4275

pii

peds.2005-0876

journal_volume

116

pub_type

杂志文章,随机对照试验
  • Cerebral blood flow velocity changes in preterm infants after a single dose of indomethacin: duration of its effect.

    abstract::Indomethacin decreases cerebral blood flow velocity and blood flow in the preterm infant. The duration of this negative effect has not been established. Cerebral blood flow velocity was evaluated in 24 preterm infants with symptomatic patent ductus arteriosus before and during the first 12 hours after a single intrave...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Van Bel F,Van de Bor M,Stijnen T,Baan J,Ruys JH

    更新日期:1989-11-01 00:00:00

  • Recognition of sleep-disordered breathing in children.

    abstract:OBJECTIVE:To determine whether upper airway resistance syndrome (UARS) can be recognized and distinguished from obstructive sleep apnea syndrome (OSAS) in prepubertal children based on clinical evaluations, and, in a subgroup of the population, to compare the efficacy of esophageal pressure (Pes) monitoring to that of ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Guilleminault C,Pelayo R,Leger D,Clerk A,Bocian RC

    更新日期:1996-11-01 00:00:00

  • Childhood overweight and maturational timing in the development of adult overweight and fatness: the Newton Girls Study and its follow-up.

    abstract:OBJECTIVE:Although several studies have suggested that early menarche is associated with the development of adult overweight, few have accounted for childhood overweight before menarche. STUDY DESIGN:A 30-year follow-up of the original participants in the Newton Girls Study, a prospective study of development in a coh...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1604

    authors: Must A,Naumova EN,Phillips SM,Blum M,Dawson-Hughes B,Rand WM

    更新日期:2005-09-01 00:00:00

  • Tachypnea of infancy as the first sign of Sanfilippo syndrome.

    abstract::This report describes the first known case of Mucopolysaccharidosis type IIIA presenting with respiratory symptoms and characteristic lung pathology. This case highlights under-recognized areas of systemic involvement and earlier modes of presentation in lysosomal storage disorders as well as the importance of investi...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-2765

    authors: Chiang J,Raiman J,Cutz E,Solomon M,Dell S

    更新日期:2014-09-01 00:00:00

  • Black-white differences in health care utilization among US children with frequent ear infections.

    abstract:OBJECTIVE:To examine differences in patterns of and barriers to health care utilization between black and white children who have frequent ear infections (FEI). METHODS:Analysis was conducted using the 1997 and 1998 National Health Interview Survey-Sample Child Files. Data on 25 497 children under 18 years of age and ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.109.5.e84

    authors: Park CH,Kogan MD,Overpeck MD,Casselbrant ML

    更新日期:2002-05-01 00:00:00

  • Improved access and quality of care after enrollment in the New York State Children's Health Insurance Program (SCHIP).

    abstract:BACKGROUND:Although many studies have noted that uninsured children have poorer access and quality of health care than do insured children, few studies have been able to demonstrate the direct benefits of providing health insurance to previously uninsured children. The State Children's Health Insurance Program (SCHIP),...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.113.5.e395

    authors: Szilagyi PG,Dick AW,Klein JD,Shone LP,Zwanziger J,McInerny T

    更新日期:2004-05-01 00:00:00

  • Rapid, needle-free delivery of lidocaine for reducing the pain of venipuncture among pediatric subjects.

    abstract:OBJECTIVES:The purpose of this study was to determine the optimal configuration of an investigational, single-use, needle-free, drug system (ALGRX 3268) that delivers powdered lidocaine into the epidermis for the rapid production of local anesthesia among pediatric subjects undergoing venipuncture. METHODS:Children 3 ...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1542/peds.2004-0656

    authors: Migdal M,Chudzynska-Pomianowska E,Vause E,Henry E,Lazar J

    更新日期:2005-04-01 00:00:00

  • Gender differences in presentation and course of disease in pediatric patients with Crohn disease.

    abstract:OBJECTIVE:The objective of this study was to determine gender differences in pediatric patients with Crohn disease. METHODS:We conducted a retrospective cohort study of 989 consecutive pediatric patients (566 boys, 423 girls) who had Crohn disease (aged 0 to 17 years at diagnosis) by using the Pediatric IBD Consortium...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-0905

    authors: Gupta N,Bostrom AG,Kirschner BS,Ferry GD,Winter HS,Baldassano RN,Gold BD,Abramson O,Smith T,Cohen SA,Heyman MB

    更新日期:2007-12-01 00:00:00

  • Transmission of hepatitis B virus infection by asymptomatic chronic HBsAg carrier mothers.

    abstract::The courses of 18 children born to 13 chronic hepatitis B surface antigen (HBsAg) carrier mothers were followed prospectively for serological and biochemical evidence of type B hepatitis. Three children developed transient HBsAg positivity accompanied by the appearance of antibody to the hepatitis B core antigen. Two ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Papaevangelou G,Hoofnagle JH

    更新日期:1979-04-01 00:00:00

  • Recurring digital fibrous tumors of childhood: a review.

    abstract::Two new cases that conform to the clinical and histopathological features of recurring digital fibrous tumor of childhood, described by Reye in 1965, are reported. This tumor, which is considered a distinct entity among the juvenile fibromatoses, characteristically presents in infancy and early childhood, involves onl...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Beckett JH,Jacobs AH

    更新日期:1977-03-01 00:00:00

  • Executive and memory function in adolescents born very preterm.

    abstract:BACKGROUND:Many preterm children display school difficulties, which may be mediated by impairment in executive function and memory. OBJECTIVE:To evaluate executive and memory function among adolescents born preterm compared with term controls at 16 years. METHODS:A total of 337 of 437 (77%) adolescents born in 1989 t...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-1421

    authors: Luu TM,Ment L,Allan W,Schneider K,Vohr BR

    更新日期:2011-03-01 00:00:00

  • Impact of postpartum hospital-stay legislation on newborn length of stay, readmission, and mortality in California.

    abstract:OBJECTIVES:The objectives of this study were to examine the impact of postpartum hospital-stay legislation on newborns' length of stay, neonatal readmissions, and 1-year mortality in California, and whether this legislation had differential impacts by demographics and complications during delivery or pregnancy. METHOD...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-3044

    authors: Datar A,Sood N

    更新日期:2006-07-01 00:00:00

  • Infant sleep problems and postnatal depression: a community-based study.

    abstract:OBJECTIVES:To describe infant sleep patterns and investigate relationships between infant sleep problems and maternal well-being in the community setting. DESIGN:Cross-sectional community survey. Setting. Maternal and Child Health Centers in 3 middle-class local government areas in Melbourne, Australia. PARTICIPANTS:...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.6.1317

    authors: Hiscock H,Wake M

    更新日期:2001-06-01 00:00:00

  • A systematic review of vocational interventions for young adults with autism spectrum disorders.

    abstract:BACKGROUND AND OBJECTIVE:Many individuals with autism spectrum disorders (ASDs) are approaching adolescence and young adulthood; interventions to assist these individuals with vocational skills are not well understood. This study systematically reviewed evidence regarding vocational interventions for individuals with A...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2012-0682

    authors: Taylor JL,McPheeters ML,Sathe NA,Dove D,Veenstra-Vanderweele J,Warren Z

    更新日期:2012-09-01 00:00:00

  • Successful Chest Radiograph Reduction by Using Quality Improvement Methodology for Children With Asthma.

    abstract:OBJECTIVES:Implementation of an asthma clinical practice guideline did not achieve desired chest radiograph (CXR) usage goals. We attempt to use quality improvement methodology to decrease the percentage of CXRs obtained for pediatric patients with acute asthma exacerbations from 29.3% to <20% and to evaluate whether d...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-4003

    authors: Watnick CS,Arnold DH,Latuska R,O'Connor M,Johnson DP

    更新日期:2018-08-01 00:00:00

  • Airway clearance in Duchenne muscular dystrophy.

    abstract::This is a summary of the presentation on airway clearance in neuromuscular disorders presented as part of the program on airway clearance in Duchenne muscular dystrophy at the 30th annual Carrell-Krusen Neuromuscular Symposium on February 20, 2008. ...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2008-2952G

    authors: Kravitz RM

    更新日期:2009-05-01 00:00:00

  • Special requirements of electronic health record systems in pediatrics.

    abstract::Some functions of an electronic health record system are much more important in providing pediatric care than in adult care. Pediatricians commonly complain about the absence of these "pediatric functions" when they are not available in electronic health record systems. To stimulate electronic health record system ven...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-3527

    authors: Spooner SA,Council on Clinical Information Technology, American Academy of Pediatrics.

    更新日期:2007-03-01 00:00:00

  • Perinatal human immunodeficiency virus-1 transmission and intrauterine growth: a cohort study in Butare, Rwanda.

    abstract:OBJECTIVE:To study the association of perinatal human immunodeficiency virus (HIV)-1 transmission with birth outcomes, including birth weight, gestational age, ponderal index, head circumference, and weight/head ratio. METHODS:Data from a prospective cohort study of 627 pregnant women and their infants in Butare, Rwan...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.102.2.e24

    authors: Weng S,Bulterys M,Chao A,Stidley CA,Dushimimana A,Mbarutso E,Saah A

    更新日期:1998-08-01 00:00:00

  • Obstructive sleep apnea and sickle cell anemia.

    abstract:OBJECTIVE:To ascertain the prevalence of and risk factors for obstructive sleep apnea syndrome (OSAS) in children with sickle cell anemia (SCA). METHODS:Cross-sectional baseline data were analyzed from the Sleep and Asthma Cohort Study, a multicenter prospective study designed to evaluate the contribution of sleep and...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-4223

    authors: Rosen CL,Debaun MR,Strunk RC,Redline S,Seicean S,Craven DI,Gavlak JC,Wilkey O,Inusa B,Roberts I,Goodpaster RL,Malow B,Rodeghier M,Kirkham FJ

    更新日期:2014-08-01 00:00:00

  • Sustained lung inflation at birth for preterm infants: a randomized clinical trial.

    abstract:BACKGROUND:Studies suggest that giving newly born preterm infants sustained lung inflation (SLI) may decrease their need for mechanical ventilation (MV) and improve their respiratory outcomes. METHODS:We randomly assigned infants born at 25 weeks 0 days to 28 weeks 6 days of gestation to receive SLI (25 cm H2O for 15 ...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2014-1692

    authors: Lista G,Boni L,Scopesi F,Mosca F,Trevisanuto D,Messner H,Vento G,Magaldi R,Del Vecchio A,Agosti M,Gizzi C,Sandri F,Biban P,Bellettato M,Gazzolo D,Boldrini A,Dani C,SLI Trial Investigators.

    更新日期:2015-02-01 00:00:00

  • Mitomycin C test for diagnostic differentiation of idiopathic aplastic anemia and Fanconi anemia.

    abstract::A cytogenetic test was developed to enable the diagnostic differentiation between Fanconi anemia and the group of disorders classified as "idiopathic" aplastic anemia. The method is based on the effect of the bifunctional alkylating agent mitomycin C (MMC) on chromosomes of peripheral lymphocytes in culture 92 to 96 h...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Cervenka J,Arthur D,Yasis C

    更新日期:1981-01-01 00:00:00

  • Spectrum and management of hypertriglyceridemia among children in clinical practice.

    abstract:OBJECTIVES:The prevalence and identification of hypertriglyceridemia in youths will likely will increase in the future as a consequence of childhood obesity and increased screening for dyslipidemias. We sought to review our clinical experience with hypertriglyceridemia, evaluate factors associated with increased trigly...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0367

    authors: Manlhiot C,Larsson P,Gurofsky RC,Smith RW,Fillingham C,Clarizia NA,Chahal N,Clarke JT,McCrindle BW

    更新日期:2009-02-01 00:00:00

  • Persistent pulmonary hypertension of the newborn treated with magnesium sulfate in premature neonates.

    abstract:OBJECTIVE:To evaluate the clinical effects of magnesium sulfate (MgSO4) in the treatment of persistent pulmonary hypertension of the newborn (PPHN) in premature infants. METHODS:This was a prospective, nonrandomized, clinical study. Seven premature neonates with PPHN were treated with MgSO4 as soon as documentation of...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:

    authors: Wu TJ,Teng RJ,Tsou KI

    更新日期:1995-09-01 00:00:00

  • Elimination of Perinatal Hepatitis B: Providing the First Vaccine Dose Within 24 Hours of Birth.

    abstract::After the introduction of the hepatitis B vaccine in the United States in 1982, a greater than 90% reduction in new infections was achieved. However, approximately 1000 new cases of perinatal hepatitis B infection are still identified annually in the United States. Prevention of perinatal hepatitis B relies on the pro...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-1870

    authors: COMMITTEE ON INFECTIOUS DISEASES.,COMMITTEE ON FETUS AND NEWBORN.

    更新日期:2017-09-01 00:00:00

  • Fruit juice intake is not related to children's growth.

    abstract:BACKGROUND:Excessive fruit juice intake (>12 ounces/day) has been reported to be associated with short stature and obesity in preschool children. OBJECTIVE:To confirm whether excess fruit juice intake was associated with short stature and obesity in preschool children, we assessed growth parameters and fruit juice int...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.103.1.58

    authors: Skinner JD,Carruth BR,Moran J 3rd,Houck K,Coletta F

    更新日期:1999-01-01 00:00:00

  • Yield of diagnostic testing in infants who have had an apparent life-threatening event.

    abstract:OBJECTIVE:Many infants who have experienced an apparent life-threatening event (ALTE) seem normal by the time they reach the hospital. Nevertheless, they typically undergo an extensive evaluation to rule out serious underlying conditions. The purpose of the present investigation was to determine the yield of different ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-0847

    authors: Brand DA,Altman RL,Purtill K,Edwards KS

    更新日期:2005-04-01 00:00:00

  • Economic evaluation of the US Environmental Protection Agency's SunWise program: sun protection education for young children.

    abstract:OBJECTIVE:The SunWise School Program is a school-based sun safety education program that was developed by the US Environmental Protection Agency and aims to teach children how to protect themselves from overexposure to the sun. The objectives of this study were to assess the health benefits of the SunWise School Progra...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-1400

    authors: Kyle JW,Hammitt JK,Lim HW,Geller AC,Hall-Jordan LH,Maibach EW,De Fabo EC,Wagner MC

    更新日期:2008-05-01 00:00:00

  • Mental development and growth in children with chronic liver disease of early and late onset.

    abstract::Comparison was made of the mental function and physical growth of 21 children in whom liver disease occurred in the first year of life with 15 patients with late (17 months of age to 12 years of age) manifestation of liver disease. Ages (mean +/- SD) at testing for the two groups was 8 +/- 3 years for the early group ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Stewart SM,Uauy R,Kennard BD,Waller DA,Benser M,Andrews WS

    更新日期:1988-08-01 00:00:00

  • Mortality and morbidity of 500- to 1,499-gram birth weight infants live-born to residents of a defined geographic region before and after neonatal intensive care.

    abstract::All very low-birth-weight infants live-born to residents of an urban southern Ontario county were studied before (1964 to 1969) and after (1973 to 1977) the introduction of neonatal intensive care. Mortality at hospital discharge decreased from 89.4% to 77.6% among infants whose birth weights were 500 to 999 gm and fr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Horwood SP,Boyle MH,Torrance GW,Sinclair JC

    更新日期:1982-05-01 00:00:00

  • Barriers to domestic violence screening in the pediatric setting.

    abstract:OBJECTIVE:By surveying practitioners in our community, we hoped to determine what pediatricians and family physicians (FPs) perceive as barriers to the American Academy of Pediatrics (AAP) Recommendation on Domestic Violence Screening. BACKGROUND:When screened in the pediatric setting, as many as 40% of mothers will d...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.108.1.98

    authors: Erickson MJ,Hill TD,Siegel RM

    更新日期:2001-07-01 00:00:00