Transmission of hepatitis B virus infection by asymptomatic chronic HBsAg carrier mothers.

Abstract:

:The courses of 18 children born to 13 chronic hepatitis B surface antigen (HBsAg) carrier mothers were followed prospectively for serological and biochemical evidence of type B hepatitis. Three children developed transient HBsAg positivity accompanied by the appearance of antibody to the hepatitis B core antigen. Two others had no detectable HBsAg but developed antibody to HBsAg. These serological manifestations of hepatitis B virus infection occurred late--6 to 24 months after birth. None of the children had clinical evidence of hepatitis and none became chronic HBsAg carriers. The infrequency of transmission of infection, the mild course of disease, and the lack of persistence of HBsAg in these children probably reflected the low level of infectivity of the chronic carrier mothers and perhaps the healthy immunologic status of the children.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Papaevangelou G,Hoofnagle JH

subject

Has Abstract

pub_date

1979-04-01 00:00:00

pages

602-5

issue

4

eissn

0031-4005

issn

1098-4275

journal_volume

63

pub_type

杂志文章
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    authors: Szilagyi PG,Rodewald LE,Humiston SG,Raubertas RF,Cove LA,Doane CB,Lind PH,Tobin MS,Roghmann KJ,Hall CB

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    更新日期:2009-10-01 00:00:00

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  • Traumatic eye injuries from collapsible wire laundry hampers.

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    更新日期:2011-10-01 00:00:00

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    更新日期:2017-08-01 00:00:00

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  • Evaluation of two tetravalent (ACYW135) meningococcal vaccines in infants and small children: a clinical study comparing immunogenicity of O-acetyl-negative and O-acetyl-positive group C polysaccharides.

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    doi:

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  • Retinopathy of prematurity-induced blindness: birth weight-specific survival and the new epidemic.

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  • Identifying Child Abuse Fatalities During Infancy.

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  • Experiences With Medical Exemptions After a Change in Vaccine Exemption Policy in California.

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    pub_type: 杂志文章

    doi:10.1542/peds.2018-1051

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  • Assessment of children's health-related quality of life in the United States with a multidimensional index.

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    authors: Simon AE,Chan KS,Forrest CB

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    journal_title:Pediatrics

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    authors: Miljeteig I,Sayeed SA,Jesani A,Johansson KA,Norheim OF

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    abstract:BACKGROUND:Universal screening of sexually active adolescents for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) has been recommended in settings in which prevalence is 2% or greater. Although believed to be above 2%, the prevalence of CT and GC infection in private practice settings has not been clearly est...

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    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

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  • Racial and ethnic disparities in medical and dental health, access to care, and use of services in US children.

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