Persistent pulmonary hypertension of the newborn treated with magnesium sulfate in premature neonates.

Abstract:

OBJECTIVE:To evaluate the clinical effects of magnesium sulfate (MgSO4) in the treatment of persistent pulmonary hypertension of the newborn (PPHN) in premature infants. METHODS:This was a prospective, nonrandomized, clinical study. Seven premature neonates with PPHN were treated with MgSO4 as soon as documentation of an interatrial right-to-left shunt was made. A loading dose of 200 mg/kg was infused over 30 minutes, followed by a maintenance dose of 20 to 50 mg/kg/h. Alveolar-arterial oxygen tension difference (AaDO2) and oxygenation index were followed up sequentially as the primary outcome measures. Blood pressures and serum electrolytes were also monitored. RESULTS:Six cases responded clinically. The decrease of AaDO2 reached significance at 36 hours, but the decrease of oxygenation index was not significant over 72 hours. Four infants survived. No significant side effects were encountered. CONCLUSION:Our results suggest that MgSO4 may be considered as an alternative treatment of PPHN in premature infants.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Wu TJ,Teng RJ,Tsou KI

subject

Has Abstract

pub_date

1995-09-01 00:00:00

pages

472-4

issue

3 Pt 1

eissn

0031-4005

issn

1098-4275

journal_volume

96

pub_type

临床试验,杂志文章
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    authors: Stoller ML,Kogan BA,Hricak H

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  • Birthweight of children with phenylketonuria.

    abstract::The assumption that children with phenylketonuria (PKU) develop normally until birth was brought into question by the recent report that PKU children weigh several hundred grams less at birth than their unaffected siblings. We have examined intrafamily differences in birthweight in 40 sibships with at least one affect...

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    authors: Rothman KJ,Pueschel SN

    更新日期:1976-12-01 00:00:00

  • A program to limit donor exposures to neonates undergoing extracorporeal membrane oxygenation.

    abstract:OBJECTIVE:Extracorporeal membrane oxygenation (ECMO) has dramatically improved the survival of neonates with life-threatening respiratory and cardiac failure. However, ECMO requires numerous transfusions with significant risks. This study evaluated the effects of changing transfusion practices and blood component manag...

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    authors: Rosenberg EM,Chambers LA,Gunter JM,Good JA

    更新日期:1994-09-01 00:00:00

  • Goat's milk as a substitute for cow's milk in undernourished children: a randomized double-blind clinical trial.

    abstract:OBJECTIVE:This paper compares the effects of goat's milk and cow's milk on weight gain and fat absorption, in children with overt malnutrition. METHODS:Thirty hospitalized malnourished children aged from 1 to 5 years were included in a randomized double-blind trial. The children were fed either goat or cow's milk with...

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Razafindrakoto O,Ravelomanana N,Rasolofo A,Rakotoarimanana RD,Gourgue P,Coquin P,Briend A,Desjeux JF

    更新日期:1994-07-01 00:00:00

  • Qualitative brain MRI at term and cognitive outcomes at 9 years after very preterm birth.

    abstract:OBJECTIVE:A prospective study was performed to assess the relationship between the appearance of cerebral MRI at term and the cognitive functioning at 9 years old in very preterm born infants. METHODS:Seventy-six very preterm born infants (birth weight <1500 g or gestational age ≤32 weeks) obtained cerebral MRI at ter...

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    pub_type: 杂志文章

    doi:10.1542/peds.2011-1735

    authors: Iwata S,Nakamura T,Hizume E,Kihara H,Takashima S,Matsuishi T,Iwata O

    更新日期:2012-05-01 00:00:00

  • Impact of very preterm birth on health care costs at five years of age.

    abstract:OBJECTIVE:We assessed the effects of very preterm birth (gestational age <32 weeks or birth weight <1501 g) and prematurity-related morbidities on health care costs during the fifth year of life. METHODS:The study population consisted of 588 very preterm children and 176 term control subjects born in 2001-2002. Costs ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-2882

    authors: Korvenranta E,Lehtonen L,Rautava L,Häkkinen U,Andersson S,Gissler M,Hallman M,Leipälä J,Peltola M,Tammela O,Linna M,PERFECT Preterm Infant Study Group.

    更新日期:2010-05-01 00:00:00

  • Metabolic correction induced by leptin replacement treatment in young children with Berardinelli-Seip congenital lipoatrophy.

    abstract:OBJECTIVE:Berardinelli-Seip syndrome is a rare congenital lipoatrophy with a severe prognosis and no efficient therapy. Children present with low leptin levels and severe metabolic complications (insulin resistance, elevated triglyceride levels, and hepatic steatosis). The objective of this study was to test safety and...

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    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2006-3165

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    更新日期:2007-08-01 00:00:00

  • Free running test for exercise-induced bronchospasm.

    abstract::The free running test has been successfully carried out in patients from 5 to 21 years old. It has the following advantages: (1) it simulates normal exercise pattern; (2) it is readily performed in any health care setting; (3) it is simple to perform and noninvasive in nature; and (4) it reveals a maximum decrease in ...

    journal_title:Pediatrics

    pub_type: 杂志文章

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    authors: Pierson WE,Bierman CW

    更新日期:1975-11-01 00:00:00

  • Preventing neonatal group B streptococcal disease: cost-effectiveness in a health maintenance organization and the impact of delayed hospital discharge for newborns who received intrapartum antibiotics.

    abstract:OBJECTIVES:To estimate the cost and health benefits of implementing a risk factor-based prevention strategy for early-onset neonatal group B streptococcal (GBS) disease, using baseline assumptions and costs from a health maintenance organization. With the risk factor-based strategy, intrapartum antibiotics (IPAs) would...

    journal_title:Pediatrics

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    doi:10.1542/peds.103.4.703

    authors: Mohle-Boetani JC,Lieu TA,Ray GT,Escobar G

    更新日期:1999-04-01 00:00:00

  • Recovery of left ventricular function following discontinuation of anthracycline chemotherapy in children.

    abstract::Echocardiographic evaluation of left ventricular (LV) performance was performed in 41 children during and following anthracycline chemotherapy. Prior to treatment LV function was normal in all patients; LV shortening fraction was 35.2 +/- 0.7% and percent of predicted velocity of circumferential fiber shortening was 1...

    journal_title:Pediatrics

    pub_type: 杂志文章

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    authors: Lewis AB,Crouse VL,Evans W,Takahashi M,Siegel SE

    更新日期:1981-07-01 00:00:00

  • Verbal autopsy methods to ascertain birth asphyxia deaths in a community-based setting in southern Nepal.

    abstract:OBJECTIVES:The goals of this study were to (1) develop an approach to ascertain birth asphyxia deaths by using verbal autopsy data from a community-based setting in Nepal, and (2) explore variations in birth asphyxia mortality fractions by using different birth asphyxia case definitions and hierarchical classifications...

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    pub_type: 杂志文章

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    更新日期:2008-05-01 00:00:00

  • Motivational Interviewing to Treat Overweight Children: 24-Month Follow-Up of a Randomized Controlled Trial.

    abstract:BACKGROUND:Pediatrician-led motivational interviewing can be an effective way of controlling BMI in overweight children in the short term. Its long-term efficacy is unknown. The primary aim was to determine whether the short-term (12-month) impact of family pediatrician-led motivational interviews on the BMI of overwei...

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    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2015-1979

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    更新日期:2016-01-01 00:00:00

  • Alterations in end-of-life support in the pediatric intensive care unit.

    abstract:OBJECTIVE:Our purpose was to examine alterations in end-of-life support in a multiinstitutional sample of PICUs. METHODS:This was a retrospective, descriptive study. Variables collected included end-of-life support category, race, length of stay, operative status, reason for admission, and Pediatric Index of Mortality...

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    更新日期:2010-10-01 00:00:00

  • Physical activity in children attending preschools.

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    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

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    authors: Olesen LG,Kristensen PL,Korsholm L,Froberg K

    更新日期:2013-11-01 00:00:00

  • Digital Media and Sleep in Childhood and Adolescence.

    abstract::Given the pervasive use of screen-based media and the high prevalence of insufficient sleep among American youth and teenagers, this brief report summarizes the literature on electronic media and sleep and provides research recommendations. Recent systematic reviews of the literature reveal that the vast majority of s...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

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    更新日期:2017-11-01 00:00:00

  • Unrecognized human immunodeficiency virus type 1 infection in a cohort of transfused neonates: a retrospective investigation.

    abstract:OBJECTIVE:To retrospectively identify unrecognized human immunodeficiency virus type 1 (HIV-1) infection among a cohort of children transfused as neonates before donated blood was routinely screened for HIV-1 antibody. METHODS:Records at a large, private, metropolitan hospital were reviewed to identify children who we...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lieb LE,Mundy TM,Goldfinger D,Pepkowitz SH,Brunell PA,Caldwell MB,Ward JW

    更新日期:1995-05-01 00:00:00

  • Trends in Weight-for-Length Among Infants in WIC From 2000 to 2014.

    abstract:OBJECTIVES:To describe the prevalence and secular trends of high weight-for-length among infants (ages, 3-23 months) in the biennial US Department of Agriculture Women, Infants, and Children Program and Participants Characteristic (WIC-PC) Survey from 2000 through 2014 (n = 16 927 120). METHODS:Weight-for-length was c...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-2034

    authors: Freedman DS,Sharma AJ,Hamner HC,Pan L,Panzera A,Smith RB,Blanck HM

    更新日期:2017-01-01 00:00:00

  • Sleep-wake cycling on amplitude-integrated electroencephalography in term newborns with hypoxic-ischemic encephalopathy.

    abstract:OBJECTIVE:The objective of this amplitude-integrated electroencephalography (aEEG) study was to evaluate the influence of perinatal hypoxia-ischemia on sleep-wake cycling (SWC) in term newborns and assess whether characteristics of SWC are of predictive value for neurodevelopmental outcome. METHODS:From a consecutive ...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.2004-0863

    authors: Osredkar D,Toet MC,van Rooij LG,van Huffelen AC,Groenendaal F,de Vries LS

    更新日期:2005-02-01 00:00:00

  • Propofol compared with the morphine, atropine, and suxamethonium regimen as induction agents for neonatal endotracheal intubation: a randomized, controlled trial.

    abstract:OBJECTIVES:The purpose of this work was to compare the efficacy of propofol, a hypnotic agent, to the regimen of morphine, atropine, and suxamethonium as an induction agent for nonemergency neonatal endotracheal intubation. We hypothesized that propofol aids intubation by allowing the continuation of spontaneous breath...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2006-2708

    authors: Ghanta S,Abdel-Latif ME,Lui K,Ravindranathan H,Awad J,Oei J

    更新日期:2007-06-01 00:00:00

  • Antibody response to diphtheria-tetanus-pertussis immunization in preterm infants who receive dexamethasone for chronic lung disease.

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    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.113.4.733

    authors: Robinson MJ,Heal C,Gardener E,Powell P,Sims DG

    更新日期:2004-04-01 00:00:00

  • Vesicoureteral reflux in the primate. IV. Infection as cause of prolonged high-grade reflux.

    abstract::High-grade reflux commonly lasts longer than moderate reflux, which disappears with maturation of the ureterovesical junction. It is known that ureteral function is affected by urinary tract infection from studies in experimental animals, as well as through clinical findings in patients with upper tract infection. Whe...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

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    更新日期:1988-07-01 00:00:00

  • Utilization of medical and health-related services among school-age children and adolescents with special health care needs (1994 National Health Interview Survey on Disability [NHIS-D] Baseline Data).

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    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.112.3.593

    authors: Weller WE,Minkovitz CS,Anderson GF

    更新日期:2003-09-01 00:00:00

  • Attitudes and beliefs of parents concerned about vaccines: impact of timing of immunization information.

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-1722R

    authors: Vannice KS,Salmon DA,Shui I,Omer SB,Kissner J,Edwards KM,Sparks R,Dekker CL,Klein NP,Gust DA

    更新日期:2011-05-01 00:00:00

  • Unimpaired outcomes for extremely low birth weight infants at 18 to 22 months.

    abstract:OBJECTIVE:The goal was to identify, among extremely low birth weight (or=85, normal neurologic examination findings, an...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-2742

    authors: Gargus RA,Vohr BR,Tyson JE,High P,Higgins RD,Wrage LA,Poole K

    更新日期:2009-07-01 00:00:00

  • Multicenter trial of cryotherapy for retinopathy of prematurity: preliminary results. Cryotherapy for Retinopathy of Prematurity Cooperative Group.

    abstract::We report the preliminary 3-month outcome of a multicenter randomized trial of cryotherapy for treatment of retinopathy of prematurity (ROP). Transscleral cryotherapy to the avascular retina was applied to one randomly selected eye when there was threshold disease (defined as five or more contiguous or eight cumulativ...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors:

    更新日期:1988-05-01 00:00:00

  • Heterogeneity of diagnoses presenting as cyclic vomiting.

    abstract:OBJECTIVE:To establish the diagnostic profile in children who present with cyclic vomiting. METHODS:We studied 225 children < 18 years of age who presented to our pediatric gastroenterology service from 1986 to 1997 with at least three discrete episodes of vomiting between which they were well. To determine the diagno...

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    pub_type: 杂志文章

    doi:10.1542/peds.102.3.583

    authors: Li BU,Murray RD,Heitlinger LA,Robbins JL,Hayes JR

    更新日期:1998-09-01 00:00:00

  • Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007.

    abstract:OBJECTIVES:The reported increasing prevalence of autism spectrum disorder (ASD) and attendant health and family impact make monitoring of ASD prevalence a public health priority. METHODS:The prevalence of parent-reported diagnosis of ASD among US children aged 3 to 17 years was estimated from the 2007 National Survey ...

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    doi:10.1542/peds.2009-1522

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    更新日期:2009-11-01 00:00:00

  • Recurrent abdominal pain in children: lactose and sucrose intolerance, a prospective study.

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    journal_title:Pediatrics

    pub_type: 杂志文章

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    更新日期:1979-07-01 00:00:00

  • Bladder Function After Fetal Surgery for Myelomeningocele.

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    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2015-2114

    authors: Brock JW 3rd,Carr MC,Adzick NS,Burrows PK,Thomas JC,Thom EA,Howell LJ,Farrell JA,Dabrowiak ME,Farmer DL,Cheng EY,Kropp BP,Caldamone AA,Bulas DI,Tolivaisa S,Baskin LS,MOMS Investigators.

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  • Improving Access to Care at Autism Treatment Centers: A System Analysis Approach.

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