Unrecognized human immunodeficiency virus type 1 infection in a cohort of transfused neonates: a retrospective investigation.

Abstract:

OBJECTIVE:To retrospectively identify unrecognized human immunodeficiency virus type 1 (HIV-1) infection among a cohort of children transfused as neonates before donated blood was routinely screened for HIV-1 antibody. METHODS:Records at a large, private, metropolitan hospital were reviewed to identify children who were transfused as neonates between January 1980 and March 1985 and discharged alive from the hospital. Multiple data sources were used to locate these children. Parents or guardians were contacted, and their children were offered HIV-1 antibody testing and physical examination. RESULTS:Of the 775 children identified as having received transfusions during the project period, 644 (83%) were located, and 443 (69%) were evaluated for HIV-1 infection. Among those evaluated, 33 (7%) had antibody to HIV-1, including 14 whose infections had not been previously diagnosed. At the time of enrollment, 13 children infected with HIV-1 were asymptomatic an average of 63 months after transfusion. CONCLUSION:HIV-1 antibody testing should be considered for all children, regardless of clinical status, who were transfused before routine blood donor screening was implemented in March 1985, particularly in areas with a high incidence of acquired immunodeficiency syndrome during those years.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Lieb LE,Mundy TM,Goldfinger D,Pepkowitz SH,Brunell PA,Caldwell MB,Ward JW

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

717-21

issue

5

eissn

0031-4005

issn

1098-4275

journal_volume

95

pub_type

杂志文章
  • Trial of daily vitamin D supplementation in preterm infants.

    abstract:OBJECTIVE:To compare the effect of 800 vs 400 IU of daily oral vitamin D3 on the prevalence of vitamin D deficiency (VDD) at 40 weeks' postmenstrual age (PMA) in preterm infants of 28 to 34 weeks' gestation. METHODS:In this randomized double-blind trial, we allocated eligible infants to receive either 800 or 400 IU of...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2012-3395

    authors: Natarajan CK,Sankar MJ,Agarwal R,Pratap OT,Jain V,Gupta N,Gupta AK,Deorari AK,Paul VK,Sreenivas V

    更新日期:2014-03-01 00:00:00

  • Protection Versus Progress: The Challenge of Research on Cannabis Use During Pregnancy.

    abstract::A central tension in pediatric research ethics arises from our desire to protect children from harm while also allowing progress toward discoveries that could improve child health. A prime example of this tension is research on a controversial yet increasingly common practice: the use of cannabis by women to treat nau...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-0818R

    authors: MacDuffie KE,Kleinhans NM,Stout K,Wilfond BS

    更新日期:2020-08-01 00:00:00

  • The Cockayne syndrome: an evaluation of hypertension and studies of renal pathology.

    abstract::Three children with renal disease, hypertension, and the Cockayne syndrome were evaluated. All patients had severe hypertension; peripheral vein renin was elevated in two patients. Renal biopsy specimens from two patients were studied by light microscopy, electron microscopy, and immunofluoresence. Immunohistologic st...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Higginbottom MC,Griswold WR,Jones KL,Vasquez MD,Mendoza SA,Wilson CB

    更新日期:1979-12-01 00:00:00

  • Prophylactic fluconazole is effective in preventing fungal colonization and fungal systemic infections in preterm neonates: a single-center, 6-year, retrospective cohort study.

    abstract:OBJECTIVE:Despite the promising preliminary results observed in extremely low birth weight (ELBW) populations, the use of fluconazole to prevent fungal colonization and infection in preterm neonates in the NICU is still an open question and not yet recommended as a standard of care. We have reviewed our 6-year series t...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-2227

    authors: Manzoni P,Arisio R,Mostert M,Leonessa M,Farina D,Latino MA,Gomirato G

    更新日期:2006-01-01 00:00:00

  • Birth weight associated with lowest neonatal mortality: infants of adolescent and adult mothers.

    abstract:OBJECTIVE:We tested the hypothesis that survival is highest for infants born in the same weight range whether mothers are adolescent or adult, comparing the weights at which infants of these mothers achieve lowest neonatal mortality. METHODS:The relationship between birth weight and neonatal mortality was studied in b...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Rees JM,Lederman SA,Kiely JL

    更新日期:1996-12-01 00:00:00

  • Media literacy education for elementary school substance use prevention: study of media detective.

    abstract:OBJECTIVES:Media Detective is a 10-lesson elementary school substance use prevention program developed on the basis of the message interpretation processing model designed to increase children's critical thinking skills about media messages and reduce intent to use tobacco and alcohol products. The purpose of this stud...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-0068

    authors: Kupersmidt JB,Scull TM,Austin EW

    更新日期:2010-09-01 00:00:00

  • Outcomes for children hospitalized with abusive versus noninflicted abdominal trauma.

    abstract:BACKGROUND:Abusive abdominal trauma (AAT) is the second leading cause of child abuse mortality. Previous outcome studies have been limited to data from trauma centers. OBJECTIVES:The goals of this study were (1) to examine mortality, length of hospitalization, and hospital charges among a national sample of children h...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-2096

    authors: Lane WG,Lotwin I,Dubowitz H,Langenberg P,Dischinger P

    更新日期:2011-06-01 00:00:00

  • Osteogenesis imperfecta in childhood: impairment and disability.

    abstract:OBJECTIVE:To determine clinical characteristics in children with osteogenesis imperfecta (OI) regarding impairment (range of joint motion and muscle strength) and disability (functional skills) in relation to the different types of the disease, and to study the correlation between characteristics of impairment and disa...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.99.2.e3

    authors: Engelbert RH,van der Graaf Y,van Empelen R,Beemer FA,Helders PJ

    更新日期:1997-02-01 00:00:00

  • Severe fatigue in adolescents: a common phenomenon?

    abstract:OBJECTIVE:The purpose of this study was to determine the prevalence of severe fatigue in adolescent boys and girls, to explore the role of lifestyle factors in fatigue, and to investigate whether severe fatigue in a healthy population is associated with depression, anxiety, and comorbid factors also observed in chronic...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-2575

    authors: ter Wolbeek M,van Doornen LJ,Kavelaars A,Heijnen CJ

    更新日期:2006-06-01 00:00:00

  • Superior vena cava syndrome in childhood: report of ten cases and review of the literature.

    abstract::Experience with ten children with superior vena cava obstruction is reported. Five patients had non-Hodgkin's lymphoma, two had Hodgkin's disease, two had benign lesions, and one patient was suspected on clinical and radiologic basis to have a lymphoma. The clinical situation at presentation was often critical and req...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Issa PY,Brihi ER,Janin Y,Slim MS

    更新日期:1983-03-01 00:00:00

  • Care coordination services in pediatric practices.

    abstract:OBJECTIVE:To examine the frequency with which pediatricians provide care coordination services to children, particularly those with special health care needs, in their practices and the barriers to providing these services. METHODS:An 8-page questionnaire was mailed to 1632 randomly selected US members of the American...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gupta VB,O'Connor KG,Quezada-Gomez C

    更新日期:2004-05-01 00:00:00

  • Biphasic anaphylactic reactions in pediatrics.

    abstract:OBJECTIVES:The objectives of this study were to: 1) determine the incidence of biphasic reactions in children with anaphylaxis; 2) establish what risk factors can predict progression to a biphasic reaction; and 3) assess the utility of inpatient observation for patients whose anaphylaxis appears to have resolved. METH...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.4.762

    authors: Lee JM,Greenes DS

    更新日期:2000-10-01 00:00:00

  • Regulation of growth of 7- to 36-month-old children by energy and fat intake in the prospective, randomized STRIP baby trial.

    abstract:OBJECTIVE:To study the fat and energy intakes of children between 7 and 36 months of age with different growth patterns. METHODS:In the Special Turku coronary Risk factor Intervention Project for Babies, children were randomized to intervention (n = 540) and control groups (n = 522) at age 7 months. The intervention w...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1542/peds.100.5.810

    authors: Niinikoski H,Viikari J,Rönnemaa T,Helenius H,Jokinen E,Lapinleimu H,Routi T,Lagström H,Seppänen R,Välimäki I,Simell O

    更新日期:1997-11-01 00:00:00

  • Age and height at diagnosis in Turner syndrome: influence of parental height.

    abstract::Age and height at diagnosis was studied in 100 patients with Turner syndrome: 41 with the 45,X karyotype and 59 with various other karyotypes. In 15 patients diagnosis was made at birth. In the remaining patients median age at diagnosis was 12.9 years in those with 45,X karyotype and 11.6 years in the others. Mean +/-...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Massa GG,Vanderschueren-Lodeweyckx M

    更新日期:1991-12-01 00:00:00

  • Effect of maternal lead burden on infant weight and weight gain at one month of age among breastfed infants.

    abstract:INTRODUCTION:Transfer of lead from bone to the bloodstream increases during lactation. However, the effect of maternal lead burden on growth in breastfed newborns is still unknown. This study examined early postnatal growth in a cohort of healthy breastfed newborns in relation to maternal bone lead burden. METHODS:Lea...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.5.1016

    authors: Sanín LH,González-Cossío T,Romieu I,Peterson KE,Ruíz S,Palazuelos E,Hernández-Avila M,Hu H

    更新日期:2001-05-01 00:00:00

  • A Centralized Approach for Practicing Genomic Medicine.

    abstract::Next-generation sequencing has revolutionized the diagnostic process, making broadscale testing affordable and applicable to almost all specialties; however, there remain several challenges in its widespread implementation. Barriers such as lack of infrastructure or expertise within local health systems and complex re...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-0855

    authors: Biswas S,Medne L,Devkota B,Bedoukian E,Berrodin D,Izumi K,Deardorff MA,Tarpinian J,Leonard J,Pyle L,Gray C,Montgomery J,Williams T,Fortunato S,Weatherly J,McEldrew D,Kaur M,Raible SE,Wilkens A,Spinner NB,Skraban C

    更新日期:2020-03-01 00:00:00

  • Epidemiologic features of Kawasaki disease in Taiwan, 1996-2002.

    abstract:OBJECTIVE:Kawasaki disease (KD) is the most common acquired heart disease in children worldwide. The incidence of KD varies among different countries, with Asian countries supposedly having higher incidences than Western countries. However, the incidence of KD in Taiwan has not been well investigated. METHODS:Since th...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-0726

    authors: Chang LY,Chang IS,Lu CY,Chiang BL,Lee CY,Chen PJ,Wang JT,Ho HN,Chen DS,Huang LM,Kawasaki Disease Research Group.

    更新日期:2004-12-01 00:00:00

  • Medicaid policy statement.

    abstract::Medicaid is a vital safety net for children that must be maintained. It is the largest single insurer of children, yet millions of children who are eligible remain unenrolled. Every effort should be made to implement expanded eligibility and streamlined enrollment procedures. Early and Periodic Screening, Diagnosis, a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-0891

    authors: American Academy of Pediatrics Committee on Child Health Financing.

    更新日期:2005-07-01 00:00:00

  • Can home visitation improve the health of women and children at environmental risk?

    abstract::We reviewed randomized trials of prenatal and infancy home-visitation programs for socially disadvantaged women and children. Some home-visitation programs were effective in improving women's health-related behaviors during pregnancy, the birth weight and length of gestation of babies born to smokers and young adolesc...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Olds DL,Kitzman H

    更新日期:1990-07-01 00:00:00

  • A block rotation in community pediatrics.

    abstract:OBJECTIVES:To develop, implement, and evaluate a 1-month block rotation in community pediatrics. INTERVENTIONS:Faculty from University of California San Diego and Naval Medical Center San Diego developed a combined and integrated curriculum for second-year residents in community pediatrics. Resident activities include...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Shope TR,Bradley BJ,Taras HL

    更新日期:1999-07-01 00:00:00

  • Prevalence and health impact of developmental disabilities in US children.

    abstract:OBJECTIVE:Data from the 1988 National Health Interview Survey--Child Health Supplement were used to examine the prevalence of selected developmental disabilities and their impact among children ages 0 through 17 years. DESIGN:The following conditions, identified through a structured in-person interview with a parent o...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Boyle CA,Decouflé P,Yeargin-Allsopp M

    更新日期:1994-03-01 00:00:00

  • Energy dose for ventricular defibrillation of children.

    abstract::Transthoracic direct current shock is the recommended treatment for ventricular fibrillation in children as in adults. To determine the appropriate energy dose, data were collected from 71 defibrillation attempts in 27 children. Sixty-three of the 71 shocks (89%) were successful in terminating fibrillation. Fifty-seve...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gutgesell HP,Tacker WA,Geddes LA,Davis S,Lie JT,McNamara DG

    更新日期:1976-12-01 00:00:00

  • Overcrowding crisis in our nation's emergency departments: is our safety net unraveling?

    abstract::Emergency departments (EDs) are a vital component in our health care safety net, available 24 hours a day, 7 days a week, for all who require care. There has been a steady increase in the volume and acuity of patient visits to EDs, now with well over 100 million Americans (30 million children) receiving emergency care...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1287

    authors: American Academy of Pediatrics Committee on Pediatric Emergency Medicine.

    更新日期:2004-09-01 00:00:00

  • Parent diet modification, child activity, or both in obese children: an RCT.

    abstract:OBJECTIVES:Outcomes of childhood obesity interventions are rarely reported beyond 1 year. We hypothesized that the impact on the BMI z score from a child-centered physical-activity program in combination with a parent-centered dietary-modification program would be greater than either program conducted alone at 24 month...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-1518

    authors: Collins CE,Okely AD,Morgan PJ,Jones RA,Burrows TL,Cliff DP,Colyvas K,Warren JM,Steele JR,Baur LA

    更新日期:2011-04-01 00:00:00

  • The Diagnosis of Polycystic Ovary Syndrome in Adolescents.

    abstract::Consensus has recently been reached by international pediatric subspecialty societies that otherwise unexplained persistent hyperandrogenic anovulation using age- and stage-appropriate standards are appropriate diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescents. The purpose of this review is to su...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2015-1430

    authors: Rosenfield RL

    更新日期:2015-12-01 00:00:00

  • Increased risk of precocious puberty in internationally adopted children in Denmark.

    abstract:BACKGROUND:Studies have indicated that internationally adopted children have an increased risk of developing precocious puberty, but no epidemiologic risk estimates have previously been calculated. We aimed to assess the risk of developing precocious puberty in intercountry adoptees, children immigrating with their fam...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-2939

    authors: Teilmann G,Pedersen CB,Skakkebaek NE,Jensen TK

    更新日期:2006-08-01 00:00:00

  • One-Year Language Outcomes in Toddlers With Language Delays: An RCT Follow-up.

    abstract:OBJECTIVES:The current study is a 1-year follow-up analysis of data from a randomized controlled trial of Enhanced Milieu Teaching (EMT) for toddlers with language delays. Outcomes and predictors of child language and parent intervention implementation were examined 6 and 12 months after the end of the intervention. M...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2016-3646

    authors: Hampton LH,Kaiser AP,Roberts MY

    更新日期:2017-11-01 00:00:00

  • Pediatricians and general practitioners: a comparison of the management of children with febrile illness.

    abstract::To assess the relative competence of pediatricians and general practitioners in managing febrile illnesses in childhood, a prospective study was undertaken of 259 children less than 10 years of age seen consecutively at the emergency room of a children's hospital and a general hospital. Both groups of patients were si...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Leduc DG,Pless IB

    更新日期:1982-10-01 00:00:00

  • Unexplained reduced microbiological efficacy of intramuscular benzathine penicillin G and of oral penicillin V in eradication of group a streptococci from children with acute pharyngitis.

    abstract:OBJECTIVE:To evaluate the efficacy of oral penicillin V and intramuscular benzathine penicillin G (BPG) in eradicating group A streptococci from the upper respiratory tract. METHODOLOGY:Two randomized, single-blind, multicenter antibiotic efficacy trials in children using recommended doses of either oral penicillin V ...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.108.5.1180

    authors: Kaplan EL,Johnson DR

    更新日期:2001-11-01 00:00:00

  • The population cost-effectiveness of interventions designed to prevent childhood depression.

    abstract:BACKGROUND AND OBJECTIVES:Depression in childhood and adolescence is common and often persists into adulthood. This study assessed the population-level cost-effectiveness of a preventive intervention that screens children and adolescents for symptoms of depression in schools and the subsequent provision of a psychologi...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-1823

    authors: Mihalopoulos C,Vos T,Pirkis J,Carter R

    更新日期:2012-03-01 00:00:00