The population cost-effectiveness of interventions designed to prevent childhood depression.

Abstract:

BACKGROUND AND OBJECTIVES:Depression in childhood and adolescence is common and often persists into adulthood. This study assessed the population-level cost-effectiveness of a preventive intervention that screens children and adolescents for symptoms of depression in schools and the subsequent provision of a psychological intervention to those showing elevated signs of depression. The target population for screening comprised 11- to 17-year-old children and adolescents in the 2003 Australian population. METHODS:Economic modeling techniques were used to assess the incremental cost-effectiveness of the intervention compared with no intervention. The perspective was that of the health sector, and outcomes were measured by using disability-adjusted life-years (DALYs). Multivariate probabilistic and univariate sensitivity testing was applied to quantify variations in the model parameters. RESULTS:The modeled psychological intervention had an incremental cost-effectiveness ratio of $5400 per DALY averted, with just 2% of iterations falling above a $50 000 per DALY value-for-money threshold. Results were robust to model assumptions. CONCLUSIONS:After school screening, screening and the psychological intervention represent good value-for-money. Such an intervention needs to be seriously considered in any national package of preventive health services. Acceptability issues, particularly to intervention providers, including schools and mental health professionals, need to be considered before wide-scale adoption.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Mihalopoulos C,Vos T,Pirkis J,Carter R

doi

10.1542/peds.2011-1823

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

e723-30

issue

3

eissn

0031-4005

issn

1098-4275

pii

peds.2011-1823

journal_volume

129

pub_type

杂志文章
  • Recognizing and responding to medical neglect.

    abstract::A caregiver may fail to recognize or respond to a child's medical needs for a variety of reasons. An effective response by a health care professional to medical neglect requires a comprehensive assessment of the child's needs, the parents' resources, the parents' efforts to provide for the needs of the child, and opti...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2007-2903

    authors: Jenny C,Committee on Child Abuse and Neglect, American Academy of Pediatrics.

    更新日期:2007-12-01 00:00:00

  • Severe perinatal Marfan syndrome.

    abstract::The cardiovascular manifestations of the Marfan syndrome in older children and adults have been well described. Clinical, radiographic, and echocardiographic data regarding three patients with severe perinatal Marfan syndrome are described. Two of these patients had the syndrome at birth and died in infancy. The syndr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gross DM,Robinson LK,Smith LT,Glass N,Rosenberg H,Duvic M

    更新日期:1989-07-01 00:00:00

  • Identification of inflicted traumatic brain injury in well-appearing infants using serum and cerebrospinal markers: a possible screening tool.

    abstract:OBJECTIVE:Inflicted traumatic brain injury (iTBI) is the leading cause of death from TBI in infants. Misdiagnosis of iTBI is common and results in increased morbidity and mortality. Biomarkers may be able to assist in screening infants who are at high risk for iTBI and whose injury might otherwise be missed. We investi...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-0711

    authors: Berger RP,Dulani T,Adelson PD,Leventhal JM,Richichi R,Kochanek PM

    更新日期:2006-02-01 00:00:00

  • Low-dose atomoxetine for maintenance treatment of attention-deficit/hyperactivity disorder.

    abstract:OBJECTIVE:Data from acute studies of atomoxetine in patients with attention-deficit/hyperactivity disorder suggest that a dose of approximately 1.2 mg/kg per day is required to attain a maximal symptom response. However, lower doses could be effective during maintenance treatment, which would reduce drug exposure and p...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2005-2999

    authors: Newcorn JH,Michelson D,Kratochvil CJ,Allen AJ,Ruff DD,Moore RJ,Atomoxetine Low-dose Study Group.

    更新日期:2006-12-01 00:00:00

  • Sensitization to silk and childhood asthma in rural China.

    abstract:OBJECTIVE:Sensitization to perennial aeroallergens is associated with asthma in industrialized countries with a Western lifestyle. Because silk products are commonly used in Chinese society, we were interested in examining the relation between sensitization to silk and asthma. DESIGN:Cross-sectional study of 871 child...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.5.e80

    authors: Celedón JC,Palmer LJ,Xu X,Wang B,Fang Z,Weiss ST

    更新日期:2001-05-01 00:00:00

  • The vulnerability of the medical student: posthumous presentation of L.L. Stephens' ideas.

    abstract::L.L. Stephens described several critical issues in medical professionalization. The encounter with morbidity and mortality heightens the student's feelings of vulnerability. If he over-identifies with patients, he may suffer more and be unable to provide rational medical care. If he protects himself by dehumanizing pa...

    journal_title:Pediatrics

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Werner ER,Korsch BM

    更新日期:1976-03-01 00:00:00

  • Premedication for nonemergent neonatal intubations: a randomized, controlled trial comparing atropine and fentanyl to atropine, fentanyl, and mivacurium.

    abstract:OBJECTIVE:The purpose of this work was to investigate whether using a muscle relaxant would improve intubation conditions in infants, thereby decreasing the incidence and duration of hypoxia and time and number of attempts needed to successfully complete the intubation procedure. PATIENTS/METHODS:This was a prospectiv...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2006-0590

    authors: Roberts KD,Leone TA,Edwards WH,Rich WD,Finer NN

    更新日期:2006-10-01 00:00:00

  • Sports Specialization and Intensive Training in Young Athletes.

    abstract::Sports specialization is becoming the norm in youth sports for a variety of reasons. When sports specialization occurs too early, detrimental effects may occur, both physically and psychologically. If the timing is correct and sports specialization is performed under the correct conditions, the athlete may be successf...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2016-2148

    authors: Brenner JS,COUNCIL ON SPORTS MEDICINE AND FITNESS.

    更新日期:2016-09-01 00:00:00

  • Skin lesions in association with beta-hemolytic Streptococcus group B.

    abstract::A full-term male infant delivered by caesarean section following a prolonged rupture of the amniotic membranes of 30 hours' duration manifested peculiar skin lesions at the time of birth consistent with the healing phase of bullous impetigo. He was colonized with beta-hemolytic Streptococcus group B that was also cult...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lopez JB,Gross P,Boggs TR

    更新日期:1976-12-01 00:00:00

  • Selective screening device for the early detection of normal or delayed cognitive development in infants at risk for later mental retardation.

    abstract::The present study tested the predictive validity at 3 years of age of a screening device for the early identification of later cognitive delay. The screening device, administered between 3 and 7 months of age, is based on the infant's differential fixation "to novel" over previously shown pictures. The sample was comp...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Fagan JF 3rd,Singer LT,Montie JE,Shepherd PA

    更新日期:1986-12-01 00:00:00

  • Effect of intramuscular vitamin E on mortality and intracranial hemorrhage in neonates of 1000 grams or less.

    abstract::A randomized, double-blind study to determine the effect of intramuscular vitamin E on mortality and intracranial hemorrhage (ICH) was performed. One hundred forty-nine neonates with birth weights less than or equal to 1000 g and less than or equal to 24 hours of age were grouped by weight (501 to 750 g and 751 to 100...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Fish WH,Cohen M,Franzek D,Williams JM,Lemons JA

    更新日期:1990-04-01 00:00:00

  • Deep venous thrombosis complicating myelomeningocele: report of three cases.

    abstract::Deep venous thrombosis is a frequent, well-recognized complication of spinal cord injury. Patients with myelomeningocele often have similar weakness of the lower extremities. Following orthopedic surgery, they may also be immobilized at a time when they are hypercoagulable. In addition, as with patients with spinal co...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bernstein ML,Esseltine D,Azouz EM,Forbes P

    更新日期:1989-11-01 00:00:00

  • High-versus low-dose, frequently administered, nebulized albuterol in children with severe, acute asthma.

    abstract::Thirty-two 5- to 17-year-old children who had severe, acute asthma were randomly assigned to receive either high doses (0.15 mg/kg of body weight per dose) or low doses (0.05 mg/kg of body weight per dose) of nebulized albuterol every 20 minutes for six doses. Compared with the low-dose regimen, the high-dose regimen ...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Schuh S,Parkin P,Rajan A,Canny G,Healy R,Rieder M,Tan YK,Levison H,Soldin SJ

    更新日期:1989-04-01 00:00:00

  • Transmission of hepatitis B virus infection by asymptomatic chronic HBsAg carrier mothers.

    abstract::The courses of 18 children born to 13 chronic hepatitis B surface antigen (HBsAg) carrier mothers were followed prospectively for serological and biochemical evidence of type B hepatitis. Three children developed transient HBsAg positivity accompanied by the appearance of antibody to the hepatitis B core antigen. Two ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Papaevangelou G,Hoofnagle JH

    更新日期:1979-04-01 00:00:00

  • Girls with attention deficit disorder: a silent minority? A report on behavioral and cognitive characteristics.

    abstract::A sample of girls and boys with attention deficit disorder (ADD) were examined for within-group sex differences and compared with control boys and girls on historical, behavioral, and cognitive characteristics. Profiles of essential and secondary features of ADD support the Diagnostic and Statistical Manual of Mental ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Berry CA,Shaywitz SE,Shaywitz BA

    更新日期:1985-11-01 00:00:00

  • Slow-release terbutaline and theophylline for the long-term therapy of children with asthma: a Latin square and factorial study of drug effects and interactions.

    abstract::To evaluate the long-term effects of slow-release formulations of theophylline and terbutaline on pulmonary function, clinical symptoms, and side effects, 24 children with stable and moderately severe perennial asthma participated in a prospective double-blind cross-over study. The patients and the treatments were ran...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Chow OK,Fung KP

    更新日期:1989-07-01 00:00:00

  • Delivery room decision-making for extremely preterm infants in Sweden.

    abstract:OBJECTIVE:To assess neonatologists' attitudes and practices regarding treatment of extremely preterm infants in the delivery room, particularly in response to parental wishes. STUDY DESIGN:Cross-sectional survey of all neonatologists in Sweden registered with the Swedish Pediatric Society. RESULTS:The response rate w...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-1885

    authors: Peerzada JM,Schollin J,Håkansson S

    更新日期:2006-06-01 00:00:00

  • Mental Health and Timing of Gender-Affirming Care.

    abstract:BACKGROUND:Gender-incongruent (GI) youth have high rates of mental health problems. Although gender-affirming medical care (GAMC) provides psychological benefit, some GI youth present to care at older ages. Whether a relationship exists between age of presentation to GAMC and mental health difficulties warrants study. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-3600

    authors: Sorbara JC,Chiniara LN,Thompson S,Palmert MR

    更新日期:2020-10-01 00:00:00

  • Media literacy education for elementary school substance use prevention: study of media detective.

    abstract:OBJECTIVES:Media Detective is a 10-lesson elementary school substance use prevention program developed on the basis of the message interpretation processing model designed to increase children's critical thinking skills about media messages and reduce intent to use tobacco and alcohol products. The purpose of this stud...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-0068

    authors: Kupersmidt JB,Scull TM,Austin EW

    更新日期:2010-09-01 00:00:00

  • Policy statement—Professional liability insurance and medicolegal education for pediatric residents and fellows.

    abstract::The American Academy of Pediatrics believes that pediatric residents and fellows should be fully informed of the scope and limitations of their professional liability insurance coverage while in training. The academy states that residents and fellows should be educated by their training institutions on matters relatin...

    journal_title:Pediatrics

    pub_type: 共识发展会议,杂志文章

    doi:10.1542/peds.2011-1025

    authors: Committee on Medical Liability and Risk Management.,Gonzalez JL

    更新日期:2011-09-01 00:00:00

  • Increasing antiretroviral drug access for children with HIV infection.

    abstract::Although there have been great gains in the prevention of pediatric HIV infection and provision of antiretroviral therapy for children with HIV infection in resource-rich countries, many barriers remain to scaling up HIV prevention and treatment for children in resource-limited areas of the world. Appropriate testing ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-0273

    authors: American Academy of Pediatrics Committee on Pediatric AIDS, Section on International Child Health.,Havens PL,Gibb DM

    更新日期:2007-04-01 00:00:00

  • Muscularity and fatness of infants and young children born small- or large-for-gestational-age.

    abstract:OBJECTIVE:There is growing interest in the extent to which body composition, both short- and long-term, differs in infants and children born at the extremes of birth weight. This is because a growing number of studies have linked low birth weight and fetal growth restriction to the chronic diseases in adulthood that of...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.102.5.e60

    authors: Hediger ML,Overpeck MD,Kuczmarski RJ,McGlynn A,Maurer KR,Davis WW

    更新日期:1998-11-01 00:00:00

  • From concept to application: the impact of a community-wide intervention to improve the delivery of preventive services to children.

    abstract:OBJECTIVE:To improve health outcomes of children, the US Maternal and Child Health Bureau has recommended more effective organization of preventive services within primary care practices and more coordination between practices and community-based agencies. However, applying these recommendations in communities is chall...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.108.3.e42

    authors: Margolis PA,Stevens R,Bordley WC,Stuart J,Harlan C,Keyes-Elstein L,Wisseh S

    更新日期:2001-09-01 00:00:00

  • Palivizumab, a Humanized Respiratory Syncytial Virus Monoclonal Antibody, Reduces Hospitalization From Respiratory Syncytial Virus Infection in High-risk Infants.

    abstract::Objective. To determine the safety and efficacy of prophylaxis with palivizumab in reducing the incidence of hospitalization because of respiratory syncytial virus (RSV) infection in high-risk infants. Methods. A randomized, double-blind, placebo-controlled trial was conducted at 139 centers in the United States, the ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1998-09-01 00:00:00

  • A multiple-source method for studying the prevalence of developmental disabilities in children: the Metropolitan Atlanta Developmental Disabilities Study.

    abstract::The Metropolitan Atlanta Developmental Disabilities Study is the first US, population-based epidemiologic study of the prevalence of mental retardation, cerebral palsy, hearing impairment, and visual impairment among school-age children. The study population consisted of children who were 10 years of age between 1985 ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Yeargin-Allsopp M,Murphy CC,Oakley GP,Sikes RK

    更新日期:1992-04-01 00:00:00

  • Unrecognized human immunodeficiency virus type 1 infection in a cohort of transfused neonates: a retrospective investigation.

    abstract:OBJECTIVE:To retrospectively identify unrecognized human immunodeficiency virus type 1 (HIV-1) infection among a cohort of children transfused as neonates before donated blood was routinely screened for HIV-1 antibody. METHODS:Records at a large, private, metropolitan hospital were reviewed to identify children who we...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lieb LE,Mundy TM,Goldfinger D,Pepkowitz SH,Brunell PA,Caldwell MB,Ward JW

    更新日期:1995-05-01 00:00:00

  • A pacifier increases the risk of recurrent acute otitis media in children in day care centers.

    abstract:OBJECTIVE:To follow up a previous retrospective analysis in which we found the use of a pacifier to be a risk factor for recurrent acute otitis media (AOM). METHOD:In the present prospective study, the occurrence of AOM and the use of a pacifier were recorded in 845 children attending day care centers during a 15-mont...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Niemelä M,Uhari M,Möttönen M

    更新日期:1995-11-01 00:00:00

  • Assessment of stress in mothers of children with severe breath-holding spells.

    abstract:BACKGROUND:Severe breath-holding spells (BHS) in children consist of a stereotypical sequence of provocation to cry, noiseless expiration, color change, and loss of consciousness. Parenting a child who exhibits BHS is likely more stressful than parenting a healthy child, owing to this additional medical concern. It is ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.1.1

    authors: Mattie-Luksic M,Javornisky G,DiMario FJ

    更新日期:2000-07-01 00:00:00

  • Heat or eat: the Low Income Home Energy Assistance Program and nutritional and health risks among children less than 3 years of age.

    abstract:OBJECTIVES:Public funding for the Low Income Home Energy Assistance Program has never been sufficient to serve more than a small minority of income-eligible households. Low Income Home Energy Assistance Program funding has not increased with recent rapidly rising energy costs, harsh winter conditions, or higher child p...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-2943

    authors: Frank DA,Neault NB,Skalicky A,Cook JT,Wilson JD,Levenson S,Meyers AF,Heeren T,Cutts DB,Casey PH,Black MM,Berkowitz C

    更新日期:2006-11-01 00:00:00

  • Research Gaps in Primary Pediatric Hypertension.

    abstract::Hypertension affects >40% of the US population and is a major contributor to cardiovascular-related morbidity and mortality. Although less common among children and adolescents, hypertension affects 1% to 5% of all youth. The 2017 Clinical Practice Guideline for the Diagnosis and Management of High Blood Pressure in C...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2018-3517

    authors: Taylor-Zapata P,Baker-Smith CM,Burckart G,Daniels SR,Flynn JT,Giacoia G,Green D,Kelly AS,Khurana M,Li JS,Pratt C,Urbina EM,Zajicek A

    更新日期:2019-05-01 00:00:00