Abstract:
:A considerable amount of data indicates that transplanted patients are at increased risk for de novo and recurrent cancer. Treatment of this population is difficult. It remains unclear if the immunosuppressive therapy should be continued, tapered or even stopped or if immunosuppressive drugs with antiproliferative properties have beneficial effects in this situation. In various models, mTOR-inhibitors were shown to have immunosuppressive and anti-tumor effects. Here, we have reviewed the current literature trying to clarify if mTOR-inhibition brings advantages for the transplanted patients suffering from tumors.
journal_name
Transplantationjournal_title
Transplantationauthors
Andrassy J,Graeb C,Rentsch M,Jauch KW,Guba Mdoi
10.1097/01.tp.0000186912.23630.85subject
Has Abstractpub_date
2005-09-27 00:00:00pages
S171-4issue
1 Suppleissn
0041-1337issn
1534-6080pii
00007890-200509271-00019journal_volume
80pub_type
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