Efficacy and safety of low molecular weight heparin in renal transplantation.

abstract：:The graft-versus-host (GVH) reaction induces thymic dysplasia and an arrest in T cell differentiation. Studies were performed to test the effect of irradiation and reconstitution with bone marrow on GVH-induced thymic dysplasia and T cell differentiation. GVH reactions were induced in CBAxAF1 adult mice by the injecti...

journal_title：Transplantation

authors： Seddik M,Seemayer TA,Lapp WS

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Few studies have directly compared preemptive therapy (PET) and antiviral prophylaxis (AP) for prevention of cytomegalovirus (CMV) disease in CMV seropositive (R+) orthotopic liver transplant (OLT) recipients. METHODS:We prospectively assessed CMV disease and clinical outcomes among 160 consecutive R+ OLT r...

journal_title：Transplantation

authors： Liu AW,Jutivorakool K,Fisher CE,Rakita RM,Reyes JD,Bhattacharya RB,Jerome KR,Limaye AP

更新日期：2018-04-01 00:00:00

abstract：:We report the management of a patient with the late onset of chronic graft-versus-host disease (GVHD) after orthotopic liver transplantation. GVHD is a rare complication of solid organ transplants that usually presents early after transplantation and is fatal in the majority of cases. Our patient differs from the typi...

journal_title：Transplantation

authors： Dunn SP,Krueger LJ,Butani L,Punnett H

更新日期：2001-05-27 00:00:00

abstract：BACKGROUND:Only four centers have reported their results with renal transplantation in human immunodeficiency virus (HIV)+ recipients on highly active antiretroviral therapy, and acute rejection (AR) rates have consistently ranged from 43% to 67%. METHODS:We examined the outcomes of eight adult HIV+ primary renal allo...

journal_title：Transplantation

authors： Gruber SA,Doshi MD,Cincotta E,Brown KL,Singh A,Morawski K,Alangaden G,Chandrasekar P,Losanoff JE,West MS,El-Amm JM

更新日期：2008-07-27 00:00:00

abstract：:Experiments were performed on the quality of renal functional recovery after 24, 48, or 72-hr hypothermic storage preservation of canine kidneys in Euro-Collins solution (EC), Collins' solution C2, hypertonic citrate solutions (HC, HC-D2O), or our new flush solution 2 (F.2). Clearance tests (inulin, paraaminohippuric ...

journal_title：Transplantation

authors： Fischer JH,Knupfer P,Beyer M

更新日期：1985-02-01 00:00:00

abstract：:The lung is one of the primary targets of acute graft-versus-host disease (GVHD), which is the principal complication that occurs after allogeneic intestinal transplantation. The purpose of this study is to investigate the involvement of Fas/Fas ligand system in pulmonary injury after rat semi-allogeneic intestinal tr...

journal_title：Transplantation

authors： Hiroyasu S,Shiraishi M,Koji T,Mamadi T,Sugawa H,Tomori H,Muto Y

更新日期：1999-10-15 00:00:00

abstract：:In a prospective randomized double-blind placebo-controlled trial, the effect of rh-SOD, given in a dose of 200 mg intravenously during surgery to cyclosporine-treated recipients of cadaveric renal allografts, on both acute and chronic rejection events as well as patient and graft survival was investigated by analyzin...

journal_title：Transplantation

authors： Land W,Schneeberger H,Schleibner S,Illner WD,Abendroth D,Rutili G,Arfors KE,Messmer K

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:We reviewed the incidence of and risk factors for venous thromboembolic complications in our population of kidney (KTx) and simultaneous kidney-pancreas transplant (SPK) recipients. METHODS:Information was collected retrospectively from a database on 1833 KTx and 276 SPK recipients who underwent transplant ...

journal_title：Transplantation

authors： Humar A,Johnson EM,Gillingham KJ,Sutherland DE,Payne WD,Dunn DL,Wrenshall LE,Najarian JS,Gruessner RW,Matas AJ

更新日期：1998-01-27 00:00:00

abstract：:The reactions of a number of LEW anti-ACI allospecific rat monoclonal antibodies were examined in a series of breeding studies. Analysis of (LEW X ACI) F2 progeny demonstrated concordance of the monoclonal class I and class II specificities with results of conventional alloantisera typing. In addition, a "gene dosage"...

journal_title：Transplantation

authors： Fuks A,Guttmann RD

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the influence of IL-10 and TGFbeta1 gene polymorphisms on the development of acute rejection and coronary disease in pediatric heart transplant recipients. METHODS:Patients were classified as either Rejectors or Nonrejectors. Coronary artery disease (CAD) was diagnosed by...

journal_title：Transplantation

authors： Di Filippo S,Zeevi A,McDade KK,Bastien O,Webber SA

更新日期：2006-03-27 00:00:00

abstract：BACKGROUND:The deleterious effect of steatosis on transplanted livers is mainly related to a microcirculation impairment. We investigated the effect of preservation duration on the recovery of isolated perfused rat steatotic livers and tested the effect of pentoxifylline (PTX), known to have a beneficial effect on hepa...

journal_title：Transplantation

authors： Arnault I,Bao YM,Sebagh M,Anjo A,Dimicoli JL,Lemoine A,Delvart V,Adam R

更新日期：2003-07-15 00:00:00

abstract：BACKGROUND:Cell-based insulin therapies can potentially improve glycemic regulation in insulin-dependent diabetic patients. Enteroendocrine cells engineered to secrete recombinant insulin have exhibited glycemic efficacy, but have been primarily studied as uncontrollable growth systems in immune incompetent mice. Furth...

journal_title：Transplantation

authors： Tiernan AR,Thulé PM,Sambanis A

更新日期：2014-09-15 00:00:00

abstract：:Despite the significant improvements that have occurred since the introduction of CsA, long-term renal allograft survival continues to be an area of concern. Management strategies that involve the use of sirolimus offer some promise. A number of observations suggest that sirolimus may have the ability to reduce the ra...

journal_title：Transplantation

authors： Kahan BD

更新日期：2001-06-15 00:00:00

abstract：BACKGROUND:Kidneys from older donors are likely to have a lower nephron mass. Nevertheless they constitute a valuable source of kidney allografts. Long cold ischemic time (CIT), with or without delayed graft function (DGF), has been associated with reduced graft survival. The aim of this study was to review the experie...

journal_title：Transplantation

authors： Asderakis A,Dyer P,Augustine T,Worthington J,Campbell B,Johnson RW

更新日期：2001-08-27 00:00:00

abstract：BACKGROUND:Many models of transplant tolerance have been found to depend on the induction of regulatory T cells (Tregs). Innate immune signals are known to suppress Tregs thereby augmenting immunity by abrogating Treg function. Such signals may also provide a barrier to transplantation tolerance mediated by Tregs. A nu...

journal_title：Transplantation

authors： Sonawane SB,Kim JI,Lee MK,Lee SH,Duff PE,Moore DJ,Lian MM,Deng S,Choi Y,Yeh H,Caton AJ,Markmann JF

更新日期：2009-11-27 00:00:00

abstract：:We reviewed coded autopsy material from 71 dogs, 46 receiving allogeneic and 25 receiving autologous bone marrow transplants, to evaluate the hypothesis that lymphocytic bronchitis is associated with severe acute graft-versus-host disease (GVHD). We found no significant correlation between the presence of lymphocytic ...

journal_title：Transplantation

authors： O'Brien KD,Hackman RC,Sale GE,Prentice R,Deeg J,Thomas ED,Storb R

更新日期：1984-03-01 00:00:00

abstract：:The benefits of cytomegalovirus (CMV) prophylaxis in preventing the direct effects of CMV infection and disease are well established; however, the impact of exposure to antiviral agents on preventing the indirect effects of CMV infection are poorly defined. This article reviews the results of current studies demonstra...

journal_title：Transplantation

authors： Pescovitz MD

更新日期：2006-07-27 00:00:00

abstract：:The purpose of this study was to investigate the effect of prostaglandin E1 on rabbit heart preservation. The hearts were arrested with cardioplegia (CP) solution, followed by intracoronary infusion of Euro-Collins (E-C) solution. They were immersed in E-C solution at 4 degrees C for 9 hr, flushed with terminal warm C...

journal_title：Transplantation

authors： Ueno T,Horita K,Okazaki Y,Itoh T,Natsuaki M

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Solitary pancreas transplants, both pancreas transplant alone (PTA) and pancreas after kidney (PAK), have higher rejection rates and lower graft survivals than simultaneous pancreas-kidney transplants (SPK). The aim of this study is to compare three different antibody induction regimens in solitary pancreas ...

journal_title：Transplantation

authors： Stegall MD,Kim DY,Prieto M,Cohen AJ,Griffin MD,Schwab TR,Nyberg SL,Velosa JA,Gloor JM,Innocenti F,Bohorquez H,Dean PG,Carpenter HA,Leontovich ON,Sterioff S,Larson TS

更新日期：2001-11-27 00:00:00

abstract：BACKGROUND:A widely held view is that any increase in the potency of an immunosuppressive agent will lead to an increase in infection and malignancy, such as life-threatening Epstein-Barr virus (EBV) induced posttransplant lymphoproliferative disorders (PTLD). We tested this paradigm by studying the effect of adding mo...

journal_title：Transplantation

authors： Birkeland SA,Andersen HK,Hamilton-Dutoit SJ

更新日期：1999-05-15 00:00:00

abstract：BACKGROUND:Acute rejection (AR) of the transplanted kidney has been identified as the major risk factor for the development of chronic rejection and immunological graft loss. However, the clinical presentation and response to AR therapy can vary considerably between recipients. METHODS:We studied the first AR episode ...

journal_title：Transplantation

authors： Ishikawa A,Flechner SM,Goldfarb DA,Myles JL,Modlin CS,Boparai N,Papajcik D,Mastroianni B,Novick AC

更新日期：1999-11-15 00:00:00

abstract：:Pulmonary thrombus formation in the region of atrial anastomosis following lung transplantation has been reported by several authors. Such patients typically present immediately after surgery with significant hemodynamic compromise causing pulmonary edema and hypoxemia. We describe a patient who presented with bilater...

journal_title：Transplantation

authors： Stang MR,Hinderliter AL,Gott KK,Paradowski LJ,Aris RM

更新日期：1996-09-15 00:00:00

abstract：:The role of TNF in the expression of GVHD and GVHD-related immunodeficiency was studied in a well-established murine GVHD model of bone marrow transplantation across minor histocompatibility barriers (B10.BR-->GBA/J) both in vitro and in vivo. Splenocytes from animals with GVHD profoundly inhibited the proliferation o...

journal_title：Transplantation

authors： Wall DA,Sheehan KC

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Osteoporosis is a well-documented complication of organ transplantation. Bisphosphonates have been shown to be effective in preventing corticosteroid-induced osteoporosis in renal transplant recipients, but data are lacking for treatment of established osteoporosis. This study reports our clinical experience...

journal_title：Transplantation

authors： Arlen DJ,Lambert K,Ioannidis G,Adachi JD

更新日期：2001-03-15 00:00:00

abstract：BACKGROUND:Despite early skepticism, the field of vascularized composite allotransplantation (VCA) has demonstrated feasibility. The ethics of VCA have moved past doubts about the morality of attempting such transplants to how to conduct them ethically. METHODS:Leaders of each program performing and/or evaluating VCA ...

journal_title：Transplantation

authors： Caplan AL,Parent B,Kahn J,Dean W,Kimberly LL,Lee WPA,Rodriguez ED

更新日期：2019-06-01 00:00:00

abstract：:Studies on liver interstitial dendritic cells (DC) indicate that the maturation and function of these important antigen-presenting cells may be suppressed by continual exposure to microbial products from the gut, in particular, bacterial lipopolysaccharide. New evidence is emerging for a role of specific intracellular...

journal_title：Transplantation

authors： Sumpter TL,Lunz JG 3rd,Demetris AJ,Thomson AW

更新日期：2009-08-15 00:00:00

abstract：:The aim of this study was to analyze the possible protective effects of a glutamine and arginine precursor (ornithine-alpha-ketoglutarate [OKG]) on the mucosa of a transplanted intestine when administered with either a defined formula oral diet (DFD) or a standard chow. Isogenic male Lewis rats (250 g) were submitted ...

journal_title：Transplantation

authors： de Oca J,Bettonica C,Cuadrado S,Vallet J,Martín E,Garcia A,Montañés T,Jaurrieta E

更新日期：1997-03-15 00:00:00

abstract：:We have tested the effects of FK506 (FK), a new immunosuppressive agent, on a rat limb allograft model. Histoincompatible BN limb allografts were rejected in untreated F344 hosts within 11 +/- 1 days (mean +/- SD) after operation. A single injection of 2 mg/kg, 10 mg/kg, or 50 mg/kg of FK on the day of limb transplant...

journal_title：Transplantation

authors： Arai K,Hotokebuchi T,Miyahara H,Arita C,Mohtai M,Sugioka Y,Kaibara N

更新日期：1989-11-01 00:00:00

abstract：:Patient entry is now complete in a prospective trial of anti-Tac, a murine IgG2a monoclonal antibody directed against the p55 chain of the human IL-2 receptor, for the prevention of renal allograft rejection. Recipients of primary cadaver allografts were randomized to receive either anti-Tac (20 mg q.d. x 10 days begi...

journal_title：Transplantation

authors： Kirkman RL,Shapiro ME,Carpenter CB,McKay DB,Milford EL,Ramos EL,Tilney NL,Waldmann TA,Zimmerman CE,Strom TB

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:The envelope glycoprotein gB of human cytomegalovirus (CMV) occurs as one of four main genotypes. Some previous studies have proposed a relationship of CMV gB genotype to the frequency of symptomatic infection and to clinical outcomes in both transplant and human immunodeficiency virus-infected populations. ...

journal_title：Transplantation

authors： Rosen HR,Corless CL,Rabkin J,Chou S

更新日期：1998-12-27 00:00:00