Beneficial effect of pentoxifylline on microvesicular steatotic livers submitted to a prolonged cold ischemia.

abstract：OBJECTIVE:Intrahepatic infusion is the most common method of islet autotransplantation. Structural and functional changes within the liver may result from a number of factors, including embolization of the terminal branches of the portal vein, the effects of high insulin concentration on surrounding hepatocytes or resp...

journal_title：Transplantation

authors： Ong SL,Pollard C,Rees Y,Garcea G,Webb M,Illouz S,Berry DP,Dennison AR

更新日期：2008-06-27 00:00:00

abstract：BACKGROUND:The timing of an acute rejection may have a variable impact on renal allograft survival. To determine whether the time of first acute transplant rejection (ATR) is an independent predictor of long-term allograft survival, we studied 31,600 first cadaveric renal transplants that were functional on the first t...

journal_title：Transplantation

authors： Leggat JE Jr,Ojo AO,Leichtman AB,Port FK,Wolfe RA,Turenne MN,Held PJ

更新日期：1997-05-15 00:00:00

abstract：BACKGROUND:Composite tissue allotransplantation (CTA) is a recently introduced option for limb replacement and reconstruction of other nonreconstructible tissue defects. As with recipients of other allotransplants, CTA recipients can experience rejection episodes that are presumed to be mediated by immune mechanisms si...

journal_title：Transplantation

authors： Cendales LC,Kirk AD,Moresi JM,Ruiz P,Kleiner DE

更新日期：2005-12-27 00:00:00

abstract：:Hepatocyte allotransplantation has been performed successfully in several small animal models for the amelioration of inborn metabolic errors. Before a human clinical trial of hepatocyte allotransplantation can be attempted, preliminary experience in a large animal model is needed. We transplanted isolated mongrel hep...

journal_title：Transplantation

authors： Benedetti E,Kirby JP,Asolati M,Blanchard J,Ward MG,Williams R,Hewett TA,Fontaine M,Pollak R

更新日期：1997-05-15 00:00:00

abstract：:Histoincompatibility was analyzed to describe as precisely as possible the sequence of gross morphological events taking place during allograft rejection among closely related conspecifics from a natural population of the bisexual lizard Cnemidophorus tigris. Two types of rejection were noted, depending on whether the...

journal_title：Transplantation

authors： Cuellar O,Smart C

更新日期：1977-08-01 00:00:00

abstract：:Chronic pulmonary disease is associated with varying degrees of cardiac dysfunction. Because of the potentially predominant effect of severe lung disease on right ventricular (RV) size and function, a reliable method to assess RV mechanics before and after lung transplantation may provide information of long-term sign...

journal_title：Transplantation

authors： Vigneswaran WT,McDougall JC,Olson LJ,Breen JF,McGregor CG,Rumberger JA

更新日期：1993-05-01 00:00:00

abstract：:The renal handling of cyclosporine was studied in ischemically damaged kidneys in New Zealand White rabbits and nonischemic control animals. CsA, 25 mg/kg/day, was administered intravenously for 10 days starting with the day of operation. Blood CsA (B CsA) was higher in the ischemic group compared with the controls (m...

journal_title：Transplantation

authors： Karim MS,Wood RF,Dawnay AB,Fulton PA

更新日期：1990-03-01 00:00:00

abstract：:Retrospective mixed leukocyte culture studies were performed in eight patients who had either rejected their marrow grafts or experienced graft-versus-host disease and in seven patients with successful marrow engraftment. In tests of pre-and post-transplant lymphocytes we found no evidence that rejection or graft-vers...

journal_title：Transplantation

authors： Opelz G,Gale RP

更新日期：1976-11-01 00:00:00

abstract：:Of 113 cyclosporine-treated primary renal allograft recipients, 60 were randomized to receive standard therapy without diltiazem (ND) and 53 received standard therapy plus diltiazem (D). There was no difference in CsA blood levels between ND and D at all intervals between 3 and 24 months follow-up, yet the D group req...

journal_title：Transplantation

authors： Chrysostomou A,Walker RG,Russ GR,d'Apice AJ,Kincaid-Smith P,Mathew TH

更新日期：1993-02-01 00:00:00

abstract：:The science of composite tissue allotransplantation (CTA) is rooted in progressive thinking by surgeons, fueled by innovative solutions, and aided by understanding the immunology of tolerance and rejection. These three factors have allowed CTA to progress from science fiction to science fact. Research using preclinica...

journal_title：Transplantation

authors： Swearingen B,Ravindra K,Xu H,Wu S,Breidenbach WC,Ildstad ST

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:Chronically elevated vasopressin (VP) plasma levels have been shown to induce accelerated renal function decline in rats with chronic renal failure. Whether endogenous VP is a renal risk factor in humans has not been investigated yet. We aimed to investigate whether, in renal transplant recipients, VP concen...

journal_title：Transplantation

authors： Meijer E,Bakker SJ,de Jong PE,Homan van der Heide JJ,van Son WJ,Struck J,Lems SP,Gansevoort RT

更新日期：2009-08-27 00:00:00

abstract：BACKGROUND:To evaluate the long-term outcome of renal transplant patients with membranoproliferative glomerulonephritis (MPGN) type I and the impact of recurrence. METHODS:The outcomes of 68 renal transplants performed between 1976 and 2009 in 63 patients with MPGN were compared with those of 136 controls matched for ...

journal_title：Transplantation

authors： Moroni G,Casati C,Quaglini S,Gallelli B,Banfi G,Montagnino G,Messa P

更新日期：2011-06-15 00:00:00

abstract：BACKGROUND:Cardiopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated with overall poor donor quality, especially for the intestinal donor, as splanchnic vasoconstriction that is intended to preserve coronary and cerebral blood flow may result in clinically relevant intestinal...

journal_title：Transplantation

authors： Matsumoto CS,Kaufman SS,Girlanda R,Little CM,Rekhtman Y,Raofi V,Laurin JM,Shetty K,Fennelly EM,Johnson LB,Fishbein TM

更新日期：2008-10-15 00:00:00

abstract：:The optimal timing of administration of free radical scavengers in lung preservation has yet to be determined. In previous studies, the oxygen free radical scavenger dimethylthiourea (DMTU) has improved pulmonary function when added to Eurocollins flush solution at the time of lung harvest and infused at the time of l...

journal_title：Transplantation

authors： Lambert CJ Jr,Egan TM

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Black kidney transplant recipients experience disproportionately high rates of graft loss. This disparity has persisted for 40 years, and improvements may be impeded based on the current public reporting of overall graft loss by US regulatory organizations for transplantation. METHODS:Longitudinal cohort st...

journal_title：Transplantation

authors： Taber DJ,Gebregziabher M,Payne EH,Srinivas T,Baliga PK,Egede LE

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Endomyocardial biopsy (EMB) remains the gold standard for acute cellular rejection (ACR) diagnosis in cardiac transplantation yet is subject to interobserver variability. A method that could avoid discordant EMB analysis would be desirable. The apoptosis rate in EMB correlates with ACR severity. Apollon inhi...

journal_title：Transplantation

authors： Aharinejad S,Andrukhova O,Gmeiner M,Thomas A,Krenn K,Zuckermann A,Grimm M

更新日期：2010-01-27 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that long-term tolerance of class I mismatched renal allografts in miniature swine is induced by a short course of cyclosporine (CyA), and that a total thymectomy 21 days before transplantation abrogates the induction of stable tolerance. We have now examined the effects of...

journal_title：Transplantation

authors： Yamada K,Ierino FL,Gianello PR,Shimizu A,Colvin RB,Sachs DH

更新日期：1999-04-27 00:00:00

abstract：:The use of cyclosporine has been associated with an increased incidence of thrombosis and endothelial cell perturbation. To explore possible mechanisms involved, we examined the effects of CSA on the activation of protein C by thrombomodulin. Cultured bovine aortic endothelial cell monolayers were incubated for 24 hr ...

journal_title：Transplantation

authors： Garcia-Maldonado M,Kaufman CE,Comp PC

更新日期：1991-03-01 00:00:00

abstract：:Rapid and precise cyclosporine measurements are necessary to maximize immunosuppression and minimize toxicity. The new cyclosporine and metabolites TDx fluorescent polarization immunoassay was studied to determine its precision, sensitivity, and stability. Further, it was compared with the existing radioimmunoassay an...

journal_title：Transplantation

authors： Schroeder TJ,Brunson ME,Pesce AJ,Hindenlang LL,Mauser PA,Ruckrigl DI,Weibel ML,Wadih G,First MR

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:We recently described a new approach that enables the generation of human/mouse chimera by adoptive transfer of human peripheral blood mononuclear cells into lethally irradiated normal strains of mice or rats, radioprotected with bone marrow from donors with severe combined immune deficiency. In such human/m...

journal_title：Transplantation

authors： Burakova T,Marcus H,Canaan A,Dekel B,Shezen E,David M,Lubin I,Segal H,Yair R

更新日期：1997-04-27 00:00:00

abstract：:High levels of tumor necrosis factor-alpha, interleukin-2, and gamma-interferon appeared in the circulation of kidney transplant recipients after the first injection of the monoclonal antibody OKT3. This initial injection was systematically followed by fever. The three cytokines were released in all patients (n = 9), ...

journal_title：Transplantation

authors： Abramowicz D,Schandene L,Goldman M,Crusiaux A,Vereerstraeten P,De Pauw L,Wybran J,Kinnaert P,Dupont E,Toussaint C

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:The management of ureteral strictures in transplanted kidney is challenging. Open surgical treatment is effective but entails significant convalescence. Holmium:yttrium-aluminum-garnet (Ho:YAG) laser endoureterotomy is useful for other types of ureteral obstruction, and we aimed to assess its long-term succe...

journal_title：Transplantation

authors： Gdor Y,Gabr AH,Faerber GJ,Wolf JS Jr

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:Although chronic kidney disease (CKD) is still a common complication, the prognosis of kidney function after liver transplantation (LT) is not well known. Moreover, kidney function after LT in children with renal involvement is unknown. METHODS:We retrospectively analyzed patients aged <20 years who underwe...

journal_title：Transplantation

authors： Sato M,Kaneko T,Ogura M,Kamei K,Ito S,Fukuda A,Sakamoto S,Kasahara M,Ishikura K

更新日期：2019-08-01 00:00:00

abstract：:Two infants born to mothers who had been given a renal transplant and who were receiving azathioprine and prednisone have been followed up for over 2 years. Initially both had lower than normal lymphocyte counts and cortisol levels. Chromosomal aberrations similar to those found in the lymphocytes of the mothers were ...

journal_title：Transplantation

authors： Price HV,Salaman JR,Laurence KM,Langmaid H

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:In the United States, 1 in 10 infants and 1 in 20 older children die on the liver transplant waiting list. Increasing split liver transplantation could increase organ availability for these children, without decreasing transplants in adults. METHODS:Using United Network for Organ Sharing Standard Transplant...

journal_title：Transplantation

authors： Perito ER,Roll G,Dodge JL,Rhee S,Roberts JP

更新日期：2019-03-01 00:00:00

abstract：:Allograft rejection results from a complex process involving both the innate and acquired immune systems. The innate immune system predominates in the early phase of the allogeneic response, during which chemokines and cell adhesion play essential roles, not only for leukocyte migration into the graft but also for fac...

journal_title：Transplantation

authors： Le Moine A,Goldman M,Abramowicz D

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:The increasing demand for transplantation has resulted in a trend toward using virologically compromised donors. We reviewed our experience with liver grafts from hepatitis-B surface antigen (HBsAg)(-), antibody to core antigen (anti-HBc)(+) donors. METHODS:Sixty-two liver transplants using HBsAg(-), anti-H...

journal_title：Transplantation

authors： Nery JR,Nery-Avila C,Reddy KR,Cirocco R,Weppler D,Levi DM,Nishida S,Madariaga J,Kato T,Ruiz P,Schiff E,Tzakis AG

更新日期：2003-04-27 00:00:00

abstract：:Human peripheral blood leukocyte (PBL)-reconstituted severe combined immunodeficient (SCID) mice (Hu-PBL-SCID) were used as a model to study xenograft rejection in humans. SCID mice were reconstituted with human PBL using a protocol that included a booster injection with anti-human CD3 antibody-primed cells. This prot...

journal_title：Transplantation

authors： Shiroki R,Naziruddin B,Shishido S,Duffy BF,Howard T,Mohanakumar T

更新日期：1997-03-27 00:00:00

abstract：BACKGROUND:Induction immunosuppressive therapy with the anti-T-cell antibody Thymoglobulin decreases the incidence of acute rejection in adult kidney transplant (KTx) recipients, but limited data are available for pediatric KTx recipients. METHODS:We conducted a historical cohort study to compare rates of survival, re...

journal_title：Transplantation

authors： Khositseth S,Matas A,Cook ME,Gillingham KJ,Chavers BM

更新日期：2005-04-27 00:00:00

abstract：:Serologic evidence of resolved hepatitis B virus (HBV) infection (HBV surface antigen negative, anti-HBV core antibody [HBc] positive) in a liver donor can be regarded as an occult infection with episomal HBV in the liver. The purpose of this study was to evaluate the safety of anti-HBc-positive living donors. Between...

journal_title：Transplantation

authors： Hwang S,Moon DB,Lee SG,Park KM,Kim KH,Ahn CS,Lee YJ,Chu CW,Yang HS,Cho SH,Oh KB,Ha TY,Min PC

更新日期：2003-02-15 00:00:00