Exercise testing in children before and after surgical treatment of aortic stenosis.

abstract：:Factors related to late narrowing of aortocoronary vein grafts are poorly understood. Repeat aortocoronary bypass graft angiography was performed in 34 patients at 13 +/- 5 months and 61 +/- 13 months after surgery. In these patients, 61 of 65 grafts (94%) were patent at 1 year; at 5 years, 39 of these patent grafts (...

journal_title：Circulation

authors： Palac RT,Meadows WR,Hwang MH,Loeb HS,Pifarre R,Gunnar RM

更新日期：1982-08-01 00:00:00

abstract：:From 1962-1977, 99 patients, mean age 65 +/- 0.5 years (range 60-81 years) underwent valve replacement for severe calcific aortic valve stenosis. Ninety-three percent of the patients were in New York Heart Association functional class III or IV. The aortic valve gradient was 76 +/- 3 mm Hg and the aortic valve area in...

journal_title：Circulation

authors： Murphy ES,Lawson RM,Starr A,Rahimtoola SH

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Experimental studies suggest that arterial injury and inflammation lead to increased neointimal growth after stenting. Despite the increased use of coronary stents in humans, there are only limited pathological data on the morphological features of in-stent restenosis. METHODS AND RESULTS:Detailed histology...

journal_title：Circulation

authors： Farb A,Weber DK,Kolodgie FD,Burke AP,Virmani R

更新日期：2002-06-25 00:00:00

abstract：BACKGROUND:The electrocardiographic short QT-interval syndrome forms a distinct clinical entity presenting with a high rate of sudden death and exceptionally short QT intervals. The disorder has recently been linked to gain-of-function mutation in KCNH2. The present study demonstrates that this disorder is genetically ...

journal_title：Circulation

authors： Bellocq C,van Ginneken AC,Bezzina CR,Alders M,Escande D,Mannens MM,Baró I,Wilde AA

更新日期：2004-05-25 00:00:00

abstract：BACKGROUND:Cardiac Na/K-ATPase (NKA) regulates intracellular Na ([Na](i)), which in turn affects intracellular Ca and thus contractility via Na/Ca exchange. Recent evidence shows that phosphorylation of the NKA-associated small transmembrane protein phospholemman (PLM) mediates beta-adrenergic-induced NKA stimulation. ...

journal_title：Circulation

authors： Despa S,Tucker AL,Bers DM

更新日期：2008-04-08 00:00:00

abstract：:A patient is described in whom a large congenital aneurysm or diverticulum of the right atrium caused repeated attacks of supraventricular arrhythmia and a strikingly reduced cardiac output. The aneurysm, which contained a large thrombus, was demonstrated by preoperative angiographic examinations. At the time of opera...

journal_title：Circulation

authors： Morrow AG,Behrendt DM

更新日期：1968-07-01 00:00:00

abstract：BACKGROUND:The growing postnatal human heart maintains electromechanical function while undergoing substantial changes of cellular topology and myocardial architecture. The capacity for growth and remodeling of ventricular myocardium in adaptation to the hemodynamic changes of early infancy later declines. This decline...

journal_title：Circulation

authors： Peters NS,Severs NJ,Rothery SM,Lincoln C,Yacoub MH,Green CR

更新日期：1994-08-01 00:00:00

abstract：:Four revolutions are transforming the cardiology of our day. The first is a social revolution. It has resulted in plummeting esteem for the medical profession reflecting disenchantment coupled with the rapid emergence of the recognition that health care is a right rather than a privilege. The second revolution, interv...

journal_title：Circulation

authors： Sobel BE

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The composition of plaque is a major determinant of coronary-related clinical syndromes. Intravascular ultrasound (IVUS) elastography has proven to be a technique capable of reflecting the mechanical properties of phantom material and the femoral arterial wall. The aim of this study was to investigate the ca...

journal_title：Circulation

authors： de Korte CL,Pasterkamp G,van der Steen AF,Woutman HA,Bom N

更新日期：2000-08-08 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF), the most common clinical arrhythmia, is a major cause of morbidity and mortality. Although AF is often associated with other cardiovascular conditions, many patients present without an obvious etiology. Inherited forms of AF exist, but the causative gene has been defined only in a s...

journal_title：Circulation

authors： Ellinor PT,Shin JT,Moore RK,Yoerger DM,MacRae CA

更新日期：2003-06-17 00:00:00

abstract：BACKGROUND:The clinical significance of pericardial biopsy is controversial. The aim of this study was to assess the feasibility and diagnostic value of 3 approaches to pericardial biopsy: fluoroscopic control and standard sampling, pericardioscopy guidance with standard sampling, and pericardioscopy guidance with exte...

journal_title：Circulation

authors： Seferović PM,Ristić AD,Maksimović R,Tatić V,Ostojić M,Kanjuh V

更新日期：2003-02-25 00:00:00

abstract：BACKGROUND:Ultrasonic angioplasty was recently shown to ablate thrombi and atherosclerotic plaques in vitro and to recanalize occluded arteries in experimental animal models. The goal of the present study was to examine the clinical feasibility of ultrasonic angioplasty. METHODS AND RESULTS:Intraoperative ultrasonic a...

journal_title：Circulation

authors： Rosenschein U,Rozenszajn LA,Kraus L,Marboe CC,Watkins JF,Rose EA,David D,Cannon PJ,Weinstein JS

更新日期：1991-06-01 00:00:00

abstract：:Background: In ISCHEMIA, an initial invasive strategy did not significantly reduce rates of cardiovascular events or all-cause mortality compared with a conservative strategy in patients with stable ischemic heart disease and moderate/severe myocardial ischemia. The most frequent component of composite cardiovascular ...

journal_title：Circulation

authors： Chaitman BR,Alexander KP,Cyr DD,Berger JS,Reynolds HR,Bangalore S,Boden WE,Lopes RD,Demkow M,Perna GP,Riezebos RK,McFalls EO,Banerjee S,Bagai A,Gosselin G,O'Brien SM,Rockhold FW,Waters DD,Thygesen KA,Stone GW,Whit

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Spontaneous transient outward potassium currents (STOCs) induce myogenic relaxation in small cerebral vessels. We found STOCs in human coronary artery vascular smooth muscle cells (VSMCs) and studied their regulation. METHODS AND RESULTS:K+ currents were recorded in human coronary VSMCs by current- and volt...

journal_title：Circulation

authors： Bychkov R,Gollasch M,Ried C,Luft FC,Haller H

更新日期：1997-01-21 00:00:00

abstract：:End-systolic pressure (PES), volume (VES), wall tension (TES) and circumference (CES) of the human left ventricle were studied at cardiac catheterization in 24 subjects with varying degrees of left ventricular dysfunction. Acute alterations in systolic load consistently resulted in changes in VES and CES, with a small...

journal_title：Circulation

authors： Grossman W,Braunwald E,Mann T,McLaurin LP,Green LH

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Vascular inflammation and subsequent matrix degradation play an important role in the development of atherosclerosis. We previously reported that adiponectin, an adipose-specific plasma protein, accumulated to the injured artery and attenuated vascular inflammatory response. Clinically, high plasma adiponect...

journal_title：Circulation

authors： Kumada M,Kihara S,Ouchi N,Kobayashi H,Okamoto Y,Ohashi K,Maeda K,Nagaretani H,Kishida K,Maeda N,Nagasawa A,Funahashi T,Matsuzawa Y

更新日期：2004-05-04 00:00:00

abstract：:A 28-year-old female undergoing elective total hip replacement experienced an anaphylactic reaction to succinylcholine. Hemodynamics, plasma histamine and catecholamines were measured. The tachycardia experienced during the reaction appeared to be secondary to the sympathoadrenal response rather than a direct chronotr...

journal_title：Circulation

authors： Moss J,Fahmy NR,Sunder N,Beaven MA

更新日期：1981-01-01 00:00:00

abstract：:Graft failure occurs in a sizeable proportion of coronary artery bypass conduits. We herein review relevant current evidence to give an overview of the incidence, pathophysiology, and clinical consequences of this multifactorial phenomenon. Thrombosis, endothelial dysfunction, vasospasm, and oxidative stress are diffe...

journal_title：Circulation

authors： Gaudino M,Antoniades C,Benedetto U,Deb S,Di Franco A,Di Giammarco G,Fremes S,Glineur D,Grau J,He GW,Marinelli D,Ohmes LB,Patrono C,Puskas J,Tranbaugh R,Girardi LN,Taggart DP,ATLANTIC (Arterial Grafting International Con

更新日期：2017-10-31 00:00:00

abstract：BACKGROUND:The aims of this study were to identify hibernating myocardium (hypocontractile, hypoperfused viable myocardium that regains contractility after revascularization) in the clinical setting and to predict functional outcome in patients with coronary artery disease after coronary revascularization. METHODS AND...

journal_title：Circulation

authors： Shivalkar B,Maes A,Borgers M,Ausma J,Scheys I,Nuyts J,Mortelmans L,Flameng W

更新日期：1996-08-01 00:00:00

abstract：:We used Doppler echocardiography to quantitate the changes in intracardiac blood flow velocities and right and left ventricular stroke volumes in 80 normal human fetuses from 19 to 40 weeks gestation. Blood flow velocity spectra across the aortic, pulmonary, tricuspid, and mitral valves were digitized to obtain peak v...

journal_title：Circulation

authors： Kenny JF,Plappert T,Doubilet P,Saltzman DH,Cartier M,Zollars L,Leatherman GF,St John Sutton MG

更新日期：1986-12-01 00:00:00

abstract：:One thousand four Medtronic Hall valves (601 mitral, 398 aortic, and five tricuspid) were implanted in 847 patients between December 1979 and June 1987. Total experience at the end of June 1987 was 2,640 patient-years of follow-up. Prothrombin time ratios were reviewed for all patients (16,866 observations), and these...

journal_title：Circulation

authors： Butchart EG,Lewis PA,Grunkemeier GL,Kulatilake N,Breckenridge IM

更新日期：1988-09-01 00:00:00

abstract：:Neutrophil activation and infiltration into the ischemic myocardium after reperfusion may limit the amount of salvageable myocardium (reperfusion injury). The effects of intravenous perfluorochemicals (Fluosol-DA) on infarct size, ventricular contractility, and neutrophil function were assessed in an occlusion-reperfu...

journal_title：Circulation

authors： Bajaj AK,Cobb MA,Virmani R,Gay JC,Light RT,Forman MB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Magnetic resonance (MR)--guided coronary artery stent placement is a challenging vascular intervention because of the small size of the coronary arteries combined with incessant motion during the respiratory and cardiac cycles. These obstacles necessitate higher temporal and higher spatial resolution real-ti...

journal_title：Circulation

authors： Spuentrup E,Ruebben A,Schaeffter T,Manning WJ,Günther RW,Buecker A

更新日期：2002-02-19 00:00:00

abstract：BACKGROUND:The role of a cluster of risk factors characteristic for the insulin resistance syndrome as a predictor for coronary heart disease (CHD) has not been studied previously. METHODS AND RESULTS:Clustering of cardiovascular risk factors was analyzed by factor analysis to investigate whether these clusters (facto...

journal_title：Circulation

authors： Lempiäinen P,Mykkänen L,Pyörälä K,Laakso M,Kuusisto J

更新日期：1999-07-13 00:00:00

abstract：BACKGROUND:Traditional risk factors have been linked to atherosclerotic heart disease in women. However, the effect of risk factors and menopausal status on the mechanism of sudden coronary death is unknown. METHODS AND RESULTS:We examined 51 cases of sudden coronary death and 15 hearts from women who died of trauma. ...

journal_title：Circulation

authors： Burke AP,Farb A,Malcom GT,Liang Y,Smialek J,Virmani R

更新日期：1998-06-02 00:00:00

abstract：:Deranged magnesium concentrations in serum and cardiovascular structures have been implicated in the pathophysiology of hypertension, ischemic heart disease, arrhythmias, and sudden death. This study was conducted to determine the status and interrelation of serum and tissue concentrations of magnesium in patients wit...

journal_title：Circulation

authors： Ralston MA,Murnane MR,Kelley RE,Altschuld RA,Unverferth DV,Leier CV

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:As part of the Worcester Heart Attack Study, a community-wide study examining changes over time in the incidence and long-term case-fatality rates of greater Worcester, Mass, residents hospitalized with confirmed acute myocardial infarction (AMI), we investigated the hypothesis that census tract-level socioe...

journal_title：Circulation

authors： Tonne C,Schwartz J,Mittleman M,Melly S,Suh H,Goldberg R

更新日期：2005-06-14 00:00:00

abstract：BACKGROUND:Paroxysmal atrial fibrillation (AF) naturally progresses toward chronic AF at an estimated rate of 15% to 30% over a 1- to 3-year period. Pulmonary vein (PV) isolation is increasingly performed for the treatment of drug-refractory paroxysmal AF. The long-term data on clinical outcome after circumferential PV...

journal_title：Circulation

authors： Ouyang F,Tilz R,Chun J,Schmidt B,Wissner E,Zerm T,Neven K,Köktürk B,Konstantinidou M,Metzner A,Fuernkranz A,Kuck KH

更新日期：2010-12-07 00:00:00

abstract：BACKGROUND:There is evidence for increased formation of free radicals in patients with hypertension, raising the possibility that NO is inactivated by free radicals, which impairs coronary endothelial function. Therefore, we tested the hypothesis that the antioxidant vitamin C could improve abnormal endothelial functio...

journal_title：Circulation

authors： Solzbach U,Hornig B,Jeserich M,Just H

更新日期：1997-09-02 00:00:00

abstract：BACKGROUND:The aim of the present study was to evaluate dynamic changes in aortic regurgitant (AR) orifice area with the use of calibrated electromagnetic (EM) flowmeters and to validate a color Doppler flow convergence (FC) method for evaluating effective AR orifice area and regurgitant volume. METHODS AND RESULTS:In...

journal_title：Circulation

authors： Shiota T,Jones M,Yamada I,Heinrich RS,Ishii M,Sinclair B,Holcomb S,Yoganathan AP,Sahn DJ

更新日期：1996-02-01 00:00:00