Only hibernating myocardium invariably shows early recovery after coronary revascularization.

abstract：BACKGROUND:The outcome of resuscitated patients after cardiac arrest complicating acute myocardial infarction remains poor, primarily because of the relatively low success rates of cardiopulmonary resuscitation management. Existing data suggest potential beneficial effects of early myocardial reperfusion, but the predi...

journal_title：Circulation

authors： Garot P,Lefevre T,Eltchaninoff H,Morice MC,Tamion F,Abry B,Lesault PF,Le Tarnec JY,Pouges C,Margenet A,Monchi M,Laurent I,Dumas P,Garot J,Louvard Y

更新日期：2007-03-20 00:00:00

abstract：BACKGROUND:Atherosclerosis is a multifactorial disorder involving inflammatory processes. These responses are associated with robust activation of signaling cascades by diverse cell surface receptors in a variety of cell types. The processes that are involved in atherosclerosis would likely require intact Ras pathways,...

journal_title：Circulation

authors： George J,Afek A,Keren P,Herz I,Goldberg I,Haklai R,Kloog Y,Keren G

更新日期：2002-05-21 00:00:00

abstract：BACKGROUND:Mildly oxidized LDL (moxLDL) is thought to play a role in atherogenesis. MoxLDL induces derivatization of cell proteins and triggers a variety of intracellular signaling. We aimed to investigate whether moxLDL-induced protein derivatization may influence the activity of platelet-derived growth factor recepto...

journal_title：Circulation

authors： Escargueil-Blanc I,Salvayre R,Vacaresse N,Jürgens G,Darblade B,Arnal JF,Parthasarathy S,Nègre-Salvayre A

更新日期：2001-10-09 00:00:00

abstract：BACKGROUND:We have previously shown that hydrogen peroxide stimulates endothelial [Ca(2+)](i) oscillations. This study was performed to determine whether posthypoxic reoxygenation stimulates [Ca(2+)](i) oscillations in vascular endothelial cells. METHODS AND RESULTS:Hypoxia (glucose-free 95% N(2)/5% CO(2) bicarbonate ...

journal_title：Circulation

authors： Hu Q,Ziegelstein RC

更新日期：2000-11-14 00:00:00

abstract：BACKGROUND:Platelet aggregation plays a critical role in myocardial infarction and stroke; however, the role of platelet secretion in atherosclerotic vascular disease is poorly understood. Therefore, we examined the hypothesis that platelet dense-granule secretion modulates thrombosis, inflammation, and atherosclerotic...

journal_title：Circulation

authors： King SM,McNamee RA,Houng AK,Patel R,Brands M,Reed GL

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Since the clinical introduction of dynamic cardiomyoplasty, a discrepancy has been observed between unchanged measurements of cardiac function and improved clinical outcome. METHODS AND RESULTS:We performed a beat-to-beat analysis of cardiac performance at rest in nine cardiomyoplasty patients 6 to 24 month...

journal_title：Circulation

authors： Schreuder JJ,van der Veen FH,van der Velde ET,Delahaye F,Alfieri O,Jegaden O,Lorusso R,Jansen JR,van Ommen V,Finet G

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:The acute effect of atrial fibrillation (AF) on the atrial effective refractory period (ERP) in humans is unknown. METHODS AND RESULTS:In 20 patients without structural heart disease, the atrial ERP was measured before and after pacing-induced AF at drive cycle lengths of 350 and 500 ms. Immediately after s...

journal_title：Circulation

authors： Daoud EG,Bogun F,Goyal R,Harvey M,Man KC,Strickberger SA,Morady F

更新日期：1996-10-01 00:00:00

abstract：:Peripheral arterial disease is one manifestation of systemic atherosclerosis. The prevalence of peripheral arterial disease increases with the age of the population. It is important to remember the significant association of coincident coronary artery disease, which is the major cause of mortality in these patients. R...

journal_title：Circulation

authors： White CJ,Gray WA

更新日期：2007-11-06 00:00:00

abstract：:One hundred consecutive men with a normal ECG at rest had a maximal treadmill test using 14 leads during and post-exercise. Coronary arteriography performed the following day revealed coronary stenoses greater than or equal to 70% in 66 patients. Test results obtained from a V5 lead were compared to different lead com...

journal_title：Circulation

authors： Chaitman BR,Bourassa MG,Wagniart P,Corbara F,Ferguson RJ

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:The degree of protection provided to the right ventricle during retrograde continuous normothermic blood cardioplegia (RCNBC) remains controversial. The purpose of this study was to determine whether RCNBC is able to provide "adequate" nutritive flow to both ventricles to prevent ischemic metabolism in norma...

journal_title：Circulation

authors： Ye J,Sun J,Shen J,Gregorash L,Summers R,Salerno TA,Deslauriers R

更新日期：1997-11-04 00:00:00

abstract：:We have compared casual indirect measurements of arterial pressure obtained 1) by the general practitioner (GP) and 2) in the outpatient clinic (OPC) with 24 hour continuous recording of direct arterial pressure in two selected group of unrestricted patients. 1) Eight asymptomatic, untreated patients with suspected hy...

journal_title：Circulation

authors： Littler WA,Honour AJ,Pugsley DJ,Sleight P

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:The optimal strategy for treating coronary bifurcation lesions remains a subject of debate. With bare-metal stents, single-stent approaches appear to be superior to systematic 2-stent strategies. Drug-eluting stents, however, have low rates of restenosis and might offer improved outcomes with complex stentin...

journal_title：Circulation

authors： Hildick-Smith D,de Belder AJ,Cooter N,Curzen NP,Clayton TC,Oldroyd KG,Bennett L,Holmberg S,Cotton JM,Glennon PE,Thomas MR,Maccarthy PA,Baumbach A,Mulvihill NT,Henderson RA,Redwood SR,Starkey IR,Stables RH

更新日期：2010-03-16 00:00:00

abstract：:There is now evidence that under resting conditions coronary vasodilator reserve exists even in the presence of myocardial ischemia. Therefore, we tested the hypothesis that a vasodilator reserve may exist during exercise so that during exercise-induced ischemia a reduction in coronary constrictor tone can be produced...

journal_title：Circulation

authors： Heusch G,Guth BD,Seitelberger R,Ross J Jr

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Epidemiological studies and animal experiments have provided evidence supporting the role of lipid peroxidation in atherogenesis and cardiovascular diseases. Direct evidence linking lipid oxidation to atherosclerotic progression in humans, however, has been lacking. We investigated the association of lipid o...

journal_title：Circulation

authors： Salonen JT,Nyyssönen K,Salonen R,Porkkala-Sarataho E,Tuomainen TP,Diczfalusy U,Björkhem I

更新日期：1997-02-18 00:00:00

abstract：:Nine patients with severe mitral disease were studied before and six months after mitral valve replacement with a three-cusp stented prosthesis using fresh autologous fascia lata tissue. Only patients in whom there was no auscultatory and angiographic evidence of incompetence of the replaced valve were selected for re...

journal_title：Circulation

authors： Taylor SH,Galvin MC,Pakrashi BC,Tulpule AT,Ionescu MI,Whitaker W

更新日期：1975-11-01 00:00:00

abstract：:The initial myocardial uptake of thallium-201 depends on myocardial blood flow distribution. The phenomenon of delayed thallium redistribution after transiently or chronically altered myocardial perfusion has been described. The net myocardial accumulation of thallium-201 after injection depends upon the net balance b...

journal_title：Circulation

authors： Grunwald AM,Watson DD,Holzgrefe HH Jr,Irving JF,Beller GA

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Since Mexican Americans have adverse patterns of risk factors for myocardial infarction relative to non-Hispanic whites, the incidence of myocardial infarction should be greater among Mexican Americans than among non-Hispanic whites. This expectation conflicts with reports generated from death certificate re...

journal_title：Circulation

authors： Goff DC,Nichaman MZ,Chan W,Ramsey DJ,Labarthe DR,Ortiz C

更新日期：1997-03-18 00:00:00

abstract：:A transvenous lead system for implantable defibrillators would obviate a surgical thoracotomy and reduce the morbidity and mortality associated with implantation. We evaluated the clinical performance of a new nonthoracotomy lead system that included a defibrillation lead in the coronary sinus. At the time of defibril...

journal_title：Circulation

authors： Yee R,Klein GJ,Leitch JW,Guiraudon GM,Guiraudon CM,Jones DL,Norris C

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The mechanisms of increased neointimal hyperplasia after coronary interventions in diabetic patients are still unknown. METHODS AND RESULTS:Glucose and insulin effects on in vitro vascular smooth muscle cell (VSMC) proliferation and migration were assessed. The effect of balloon injury on neointimal hyperpl...

journal_title：Circulation

authors： Indolfi C,Torella D,Cavuto L,Davalli AM,Coppola C,Esposito G,Carriero MV,Rapacciuolo A,Di Lorenzo E,Stabile E,Perrino C,Chieffo A,Pardo F,Chiariello M

更新日期：2001-06-19 00:00:00

abstract：BACKGROUND:The impact of misinterpretation of the ECG in patients with acute myocardial infarction (AMI) in the emergency department (ED) setting is not well known. Our goal was to assess the prevalence of the failure to identify high-risk ECG findings in ED patients with AMI and to determine whether this failure is as...

journal_title：Circulation

authors： Masoudi FA,Magid DJ,Vinson DR,Tricomi AJ,Lyons EE,Crounse L,Ho PM,Peterson PN,Rumsfeld JS,Emergency Department Quality in Myocardial Infarction Study Investigators.

更新日期：2006-10-10 00:00:00

abstract：BACKGROUND:The transient outward potassium current (I(to)) encoded by the Kv4 family of potassium channels is important in the repolarization of cardiac myocytes. KChIPs are a recently identified group of Ca2+-binding accessory subunits that modulate Kv4-encoded currents. KChIP2 is the only family member expressed in t...

journal_title：Circulation

authors： Deschênes I,DiSilvestre D,Juang GJ,Wu RC,An WF,Tomaselli GF

更新日期：2002-07-23 00:00:00

abstract：BACKGROUND:Joint National Committee goal blood pressure for all adults was <140/<90 mm Hg or lower from 1984 to 2013. Adults aged ≥60 years (older) have mainly isolated systolic hypertension, with major trials attaining systolic blood pressure <150 but not <140 mm Hg. The main objective was to assess changes in hyperte...

journal_title：Circulation

authors： Egan BM,Li J,Shatat IF,Fuller JM,Sinopoli A

更新日期：2014-05-20 00:00:00

abstract：:Statistical multivariate and conventional deterministic methods of computerized interpretation of the electrocardiogram (ECG) were compared in the analysis of 1711 pediatric orthogonal ECGs validated by nonelectrocardiographic criteria on the basis of clinical and anatomic diagnoses. Among 642 children catheterized fo...

journal_title：Circulation

authors： Brohet CR,Robert A,Derwael C,Fesler R,Stijns M,Vliers A,Braasseur LA

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Carotid artery stenting (CAS) has recently emerged as a potential alternative to carotid endarterectomy. Cerebral embolization is the most devastating complication of CAS, and the echogenicity of carotid plaque has been indicated as one of the risk factors involved. This is the first study to analyze the rol...

journal_title：Circulation

authors： Biasi GM,Froio A,Diethrich EB,Deleo G,Galimberti S,Mingazzini P,Nicolaides AN,Griffin M,Raithel D,Reid DB,Valsecchi MG

更新日期：2004-08-10 00:00:00

abstract：:The current dispute over the effects of "low" vs "high" doses of aspirin should take into consideration the pharmacokinetics of this drug. In fact, different pharmaceutical formulations of aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in healthy volunteers taking 320 ...

journal_title：Circulation

authors： de Gaetano G,Cerletti C,Dejana E,Latini R

更新日期：1985-12-01 00:00:00

abstract：:Few data are available regarding the effects of exercise training upon cardiac structure and performance in man. We evaluated the echograms of 24 normals before (PRE) and after (POST) 11 weeks of endurance exercise training. Conditioning consisted of a walk-jog-run protocol at 70% maximal heart rate for one hour four ...

journal_title：Circulation

authors： DeMaria AN,Neumann A,Lee G,Fowler W,Mason DT

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Accessory pathways originating at the tricuspid annulus that exhibit decremental antegrade conduction properties (Mahaim-type preexcitation) are amenable to radiofrequency (RF) current catheter ablation. However, a reliable and reproducible strategy for mapping and ablation of these fibers is lacking. METHO...

journal_title：Circulation

authors： Cappato R,Schlüter M,Weiss C,Siebels J,Hebe J,Duckeck W,Mletzko RU,Kuck KH

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Soluble stem cell factor (SCF) has been shown to mobilize bone marrow stem cells and improve cardiac repair after myocardial infarction (MI). However, the effect of membrane-associated SCF on cardiac remodeling after MI is not known. The present study investigated the effects of cardiomyocyte-specific overex...

journal_title：Circulation

authors： Xiang FL,Lu X,Hammoud L,Zhu P,Chidiac P,Robbins J,Feng Q

更新日期：2009-09-22 00:00:00

abstract：BACKGROUND:Progression of heart failure after initial myocardial injury is mediated in part by various redundant inflammatory mediators, including the widely expressed cyclooxygenase-2 (COX-2). Because COX-2 inhibitors are useful in treating many inflammation-mediated diseases, we asked whether COX-2 inhibition can att...

journal_title：Circulation

authors： Delgado RM 3rd,Nawar MA,Zewail AM,Kar B,Vaughn WK,Wu KK,Aleksic N,Sivasubramanian N,McKay K,Mann DL,Willerson JT

更新日期：2004-03-23 00:00:00

abstract：:The status of radioactive tracer studies in cardiovascular diagnosis is summarized. Planning guidelines are suggested for a hospital nuclear medical service including a central nuclear medical facility and satellite units, and resource criteria are given for professional personnel including training and duties, equipm...

journal_title：Circulation

authors： Adelstein SJ,Jansen C,Wagner HN Jr

更新日期：1975-07-01 00:00:00