Congenital aneurysm (diverticulum) of the right atrium. Clinical manifestations and results of operative treatment.

abstract：BACKGROUND:The suggestion that increased QT dispersion (QTD) is due to increased differences in local action potential durations within the myocardium is wanting. An alternative explanation was sought by relating QTD to vectorcardiographic T-loop morphology. METHODS AND RESULTS:The T loop is characterized by its ampli...

journal_title：Circulation

authors： Kors JA,van Herpen G,van Bemmel JH

更新日期：1999-03-23 00:00:00

abstract：BACKGROUND:Platelet-rich thrombus formation is a critical event in the onset of cardiovascular disease. Because ADP plays a significant role in platelet aggregation, its metabolism is important in the regulation of platelet activation and recruitment. Ectonucleoside triphosphate diphosphohydrolase (E-NTPDase) is a key ...

journal_title：Circulation

authors： Furukoji E,Matsumoto M,Yamashita A,Yagi H,Sakurai Y,Marutsuka K,Hatakeyama K,Morishita K,Fujimura Y,Tamura S,Asada Y

更新日期：2005-02-15 00:00:00

abstract：BACKGROUND:Fibrinogen has been identified as an independent risk factor for cardiovascular disease and associated with traditional cardiovascular risk factors. Also, the role of elevated fibrinogen in thrombosis suggests that it may be on the causal pathway for certain risk factors to exert their effect. These associat...

journal_title：Circulation

authors： Stec JJ,Silbershatz H,Tofler GH,Matheney TH,Sutherland P,Lipinska I,Massaro JM,Wilson PF,Muller JE,D'Agostino RB Sr

更新日期：2000-10-03 00:00:00

abstract：BACKGROUND:Wine consumption decreases the risk of myocardial infarction. Intimal hyperplasia contributes to restenosis after angioplasty. Local ethanol delivery inhibits intimal hyperplasia after balloon injury in rabbit iliac and pig coronary arteries. The effects of wine consumption on intimal response and monocyte c...

journal_title：Circulation

authors： Feng AN,Chen YL,Chen YT,Ding YZ,Lin SJ

更新日期：1999-11-30 00:00:00

abstract：BACKGROUND:Evidence suggests that the vessel wall contains an oxidase similar, if not identical, to phagocytic NADPH oxidase. We tested the contribution of this specific oxidase to the progression of atherosclerosis and the regulation of blood pressure. METHODS AND RESULTS:An examination of aortic rings from wild-type...

journal_title：Circulation

authors： Hsich E,Segal BH,Pagano PJ,Rey FE,Paigen B,Deleonardis J,Hoyt RF,Holland SM,Finkel T

更新日期：2000-03-21 00:00:00

abstract：BACKGROUND:This article presents an update of the results achieved by modern surgery in congenital heart defects (CHDs) over the past 40 years regarding survival and the need for reoperations, especially focusing on the results from the past 2 decades. METHODS AND RESULTS:From 1971 to 2011, all 7038 patients <16 years...

journal_title：Circulation

authors： Erikssen G,Liestøl K,Seem E,Birkeland S,Saatvedt KJ,Hoel TN,Døhlen G,Skulstad H,Svennevig JL,Thaulow E,Lindberg HL

更新日期：2015-01-27 00:00:00

abstract：BACKGROUND:The ability of apolipoprotein (apo)A-I to induce regression of preexisting atherosclerotic lesions has not been determined, and a mouse model of atherosclerosis regression has not yet been reported. METHODS AND RESULTS:LDL receptor-deficient mice were fed a western-type diet for 5 weeks to induce atheroscle...

journal_title：Circulation

authors： Tangirala RK,Tsukamoto K,Chun SH,Usher D,Puré E,Rader DJ

更新日期：1999-10-26 00:00:00

abstract：BACKGROUND:We investigated the feasibility and efficacy of polyethylenimine (PEI) based human vascular endothelial growth factor-165 (hVEGF165) gene transfer into human skeletal myoblasts (HSM) for cell based delivery to the infarcted myocardium. METHODS AND RESULTS:Based on optimized transfection procedure using enha...

journal_title：Circulation

authors： Ye L,Haider HKh,Tan R,Toh W,Law PK,Tan W,Su L,Zhang W,Ge R,Zhang Y,Lim Y,Sim EK

更新日期：2007-09-11 00:00:00

abstract：BACKGROUND:In recent clinical trials, glycoprotein IIb/IIIa blockers have demonstrated effectiveness in preventing adverse events after angioplasty in high-risk patients. However, uncertainty exists regarding the cost-effective selection of patients to receive antiplatelet therapy. METHODS AND RESULTS:All 4962 patient...

journal_title：Circulation

authors： Weintraub WS,Thompson TD,Culler S,Boccuzzi SJ,Becker ER,Kosinski AS,Mahoney E

更新日期：2000-07-25 00:00:00

abstract：:The continuity equation suggests that a ratio of velocities at two different cardiac valves is inversely proportional to the ratio of cross-sectional areas of the valves. To determine whether a ratio of mitral/aortic valve orifice velocities is useful in determining aortic valve area in patients with aortic stenosis, ...

journal_title：Circulation

authors： Richards KL,Cannon SR,Miller JF,Crawford MH

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Radiofrequency ablation of type 1 atrial flutter (AF1) has recently evolved toward an anatomically guided procedure directed to isthmuses at the lower part of the right atrium (RA). However, different types of block at these isthmuses may be observed and potentially correlated with different late outcomes. I...

journal_title：Circulation

authors： Poty H,Saoudi N,Nair M,Anselme F,Letac B

更新日期：1996-12-15 00:00:00

abstract：BACKGROUND:Conflicting results from recent observational studies have raised questions concerning the benefit of β-blockers for patients undergoing coronary artery bypass grafting (CABG). Furthermore, the efficacy of long-term β-blocker therapy in CABG patients after hospital discharge is uncertain. METHODS AND RESULT...

journal_title：Circulation

authors： Zhang H,Yuan X,Zhang H,Chen S,Zhao Y,Hua K,Rao C,Wang W,Sun H,Hu S,Zheng Z

更新日期：2015-06-23 00:00:00

abstract：:The amplitude and distribution of epicardial ST-segment elevation (ST) were examined for an 8-hour period after coronary occlusion in eight baboons and five pigs. ST was determined from unipolar epicardial electrograms obtained from a high-resolution matrix of fixed electrodes overlying a transmural region of ischemia...

journal_title：Circulation

authors： Smith GT,Geary G,Ruf W,Roelofs TH,McNamara JJ

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:In the event of rupture of an abdominal aortic aneurysm (AAA), mortality is very high. AAA prevalence and incidence of ruptures have been reported to be decreasing. The treatment of AAA has also undergone a change in recent decades with a shift toward endovascular aneurysm repair (EVAR). Our aim was to evalu...

journal_title：Circulation

authors： Laine MT,Laukontaus SJ,Sund R,Aho PS,Kantonen I,Albäck A,Venermo M

更新日期：2017-10-31 00:00:00

abstract：BACKGROUND:Thrombus regression in heparin-treated, acute deep venous thrombosis of the lower extremity is poorly documented in the literature; different rates of thrombus resolution and recanalization are reported. METHODS AND RESULTS:In a prospective follow-up study, duplex scanning was used to evaluate the thrombus ...

journal_title：Circulation

authors： van Ramshorst B,van Bemmelen PS,Hoeneveld H,Faber JA,Eikelboom BC

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Nontranscriptional signaling through estrogen receptors (ERs) is important in the cardiovascular system. In particular, estrogen stimulates endothelial NO synthase (eNOS) via the phosphatidylinositol 3-kinase (PI3K) pathway. The selective estrogen receptor modulator (SERM) raloxifene is effective for the tre...

journal_title：Circulation

authors： Simoncini T,Genazzani AR,Liao JK

更新日期：2002-03-19 00:00:00

abstract：BACKGROUND:The role of angiotensin as a vasoconstrictor is well established. Lately, several other actions of this hormone on vascular smooth muscle (VSM) cells have been recognized including the induction of hypertrophy and/or DNA synthesis. Platelet-derived growth factor (PDGF), a mitogen recently shown to increase p...

journal_title：Circulation

authors： van Leeuwen RT,Kol A,Andreotti F,Kluft C,Maseri A,Sperti G

更新日期：1994-07-01 00:00:00

abstract：:To test the hypothesis that an area of slow conduction is present during reentrant ventricular tachycardia in man, and that the earliest activation site during ventricular tachycardia is within or orthodromically just distal to the area of slow conduction in the reentry loop, we studied 12 episodes of ventricular tach...

journal_title：Circulation

authors： Okumura K,Olshansky B,Henthorn RW,Epstein AE,Plumb VJ,Waldo AL

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Angiotensin (Ang) II type 1 receptor (AT1-R) induces cardiomyocyte hypertrophy and fibroblast proliferation, whereas the physiological role of AT2-R in cardiac remodeling remains poorly defined. METHODS AND RESULTS:Using Bio14.6 cardiomyopathic (CM) hamsters, we found that AT2-R sites were increased by 153%...

journal_title：Circulation

authors： Ohkubo N,Matsubara H,Nozawa Y,Mori Y,Murasawa S,Kijima K,Maruyama K,Masaki H,Tsutumi Y,Shibazaki Y,Iwasaka T,Inada M

更新日期：1997-12-02 00:00:00

abstract：BACKGROUND:Congestive heart failure (CHF) is characterized by enhanced immune activation, and immune-mediated mechanisms may play a pathogenic role in this disorder. Based on the immunomodulatory effects of intravenous immunoglobulin (IVIG), we hypothesized that IVIG could downregulate inflammatory responses in CHF pat...

journal_title：Circulation

authors： Gullestad L,Aass H,Fjeld JG,Wikeby L,Andreassen AK,Ihlen H,Simonsen S,Kjekshus J,Nitter-Hauge S,Ueland T,Lien E,Frøland SS,Aukrust P

更新日期：2001-01-16 00:00:00

abstract：:Ventricular tachycardia is unusual in infancy. Three infants are described in whom this arrhythmia was documented by electrophysiologic studies. The ability to start and terminate this rhythm by critically timed premature ventricular stimulation suggests a reentrant mechanism. All three patients have remained free of ...

journal_title：Circulation

authors： Gaum WE,Schwartz DC,Kaplan S

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:Resetting has been used to characterize reentrant circuits causing clinical tachycardias. METHODS AND RESULTS:To determine the mechanisms of resetting, sustained ventricular tachycardia was induced in dogs with 4-day-old myocardial infarctions by programmed stimulation. Premature stimulation was accomplishe...

journal_title：Circulation

authors： Hanna MS,Coromilas J,Josephson ME,Wit AL,Peters NS

更新日期：2001-02-27 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). TNF-alpha-converting enzyme (TACE) has recently been purified and its complementary DNA cloned. The expression of TACE results in the production of a functional enzyme that has precursor TNF-alpha...

journal_title：Circulation

authors： Satoh M,Nakamura M,Saitoh H,Satoh H,Maesawa C,Segawa I,Tashiro A,Hiramori K

更新日期：1999-06-29 00:00:00

abstract：:Valve-related complications after Björk-Shiley mitral valve implantation (n = 475), aortic valve implantation (n = 424), or mitral-aortic valve implantation (n = 119) were compared with those after St. Jude Medical mitral valve replacement (n = 173), aortic valve replacement (n = 152), or mitral-aortic valve replaceme...

journal_title：Circulation

authors： Horstkotte D,Körfer R,Seipel L,Bircks W,Loogen F

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:The regional wall motion impairment and predisposition to arrhythmias in human ventricular hibernation may plausibly result from abnormal intercellular propagation of the depolarizing wave front. This study investigated the hypothesis that altered patterns of expression of connexin43, the principal gap junct...

journal_title：Circulation

authors： Kaprielian RR,Gunning M,Dupont E,Sheppard MN,Rothery SM,Underwood R,Pennell DJ,Fox K,Pepper J,Poole-Wilson PA,Severs NJ

更新日期：1998-02-24 00:00:00

abstract：BACKGROUND:Right ventricular function may be an important determinant of exercise capacity, peak oxygen consumption (VO2), and the ventilatory response to carbon dioxide production (VE/VCO2 relation) in patients with chronic heart failure (CHF). METHODS AND RESULTS:We studied the role of right ventricular function in ...

journal_title：Circulation

authors： Clark AL,Swan JW,Laney R,Connelly M,Somerville J,Coats AJ

更新日期：1994-05-01 00:00:00

abstract：:The nitrovasodilators are a diverse group of pharmacological agents that produce vascular relaxation by releasing nitric oxide. The mechanisms by which these compounds release nitric oxide vary, depending on their chemical structure. Compounds with lower oxidation states of nitrogen such as nitroprusside, nitrosamines...

journal_title：Circulation

authors： Harrison DG,Bates JN

更新日期：1993-05-01 00:00:00

abstract：:Thirteen patients with proven Q fever endocarditis and three additional patients with probable endocarditis are reviewed. The most helpful diagnostic test is the demonstration of a high complement fixing antibody titre to Phase 1 antigen of Coxiella burneti. The macroscopic pathology of the aortic valve is described a...

journal_title：Circulation

authors： Wilson HG,Neilson GH,Galea EG,Stafford G,O'Brien MF

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Mutations in sarcomere protein, PRKAG2, LAMP2, alpha-galactosidase A (GLA), and several mitochondrial genes can cause rare familial cardiomyopathies, but their contribution to increased left ventricular wall thickness (LVWT) in the community is unknown. METHODS AND RESULTS:We studied 1862 unrelated particip...

journal_title：Circulation

authors： Morita H,Larson MG,Barr SC,Vasan RS,O'Donnell CJ,Hirschhorn JN,Levy D,Corey D,Seidman CE,Seidman JG,Benjamin EJ

更新日期：2006-06-13 00:00:00

abstract：:Early afterdepolarizations (EADs) are depolarizing potentials that occur before complete repolarization. They may be important in the acquired and possibly the idiopathic long QT syndrome and associated ventricular tachycardia (VT). The purpose of these experiments was to study in 20 open-chest dogs the effects of sym...

journal_title：Circulation

authors： Ben-David J,Zipes DP

更新日期：1988-11-01 00:00:00