Abstract:
BACKGROUND:Magnetic resonance (MR)--guided coronary artery stent placement is a challenging vascular intervention because of the small size of the coronary arteries combined with incessant motion during the respiratory and cardiac cycles. These obstacles necessitate higher temporal and higher spatial resolution real-time MR imaging techniques when compared with interventional peripheral MR angiography. METHODS AND RESULTS:A new, ultrafast, real-time MR imaging technique that combines steady-state free precession (SSFP) for high signal-to-noise ratio and radial k-space sampling (rSSFP) for motion artifact suppression was implemented on a 1.5-T clinical whole-body interventional MR scanner. The sliding window reconstruction technique yielded a frame rate of 15/s allowing for data acquisition during free breathing and without cardiac triggering. Eleven balloon-expandable stainless steel coronary stents were placed in both coronary arteries of 7 pigs (40 to 70 kg body weight) using a nitinol guidewire and passive device visualization. Position of the coronary stents was controlled by a navigator-gated free-breathing ECG-triggered three-dimensional SSFP coronary MRA sequence and confirmed visually on the ex vivo heart. The presented real-time MR imaging sequence reliably allowed for high-quality coronary MR fluoroscopy without motion artifacts in all pigs. Ten of 11 coronary stents were correctly placed under MR guidance. One stent dislodged proximally from the left main coronary artery because of too-small balloon size. Stent dislocation was correctly predicted during real-time MR imaging. CONCLUSION:The presented approach allows for real-time MR-guided coronary artery stent placement in a swine model.
journal_name
Circulationjournal_title
Circulationauthors
Spuentrup E,Ruebben A,Schaeffter T,Manning WJ,Günther RW,Buecker Adoi
10.1161/hc0702.104165subject
Has Abstractpub_date
2002-02-19 00:00:00pages
874-9issue
7eissn
0009-7322issn
1524-4539journal_volume
105pub_type
杂志文章相关文献
CIRCULATION文献大全abstract:BACKGROUND:Pulmonary hypertension induced by chronic hypoxia is characterized by thickening of pulmonary artery walls, elevated pulmonary vascular resistance, and right-heart failure. Prostacyclin analogues reduce pulmonary pressures in this condition; raising the possibility that cycloxygenase-2 (COX-2) modulates the ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000145613.01188.0B
更新日期:2004-10-26 00:00:00
abstract:BACKGROUND:Primum atrial septal defect (ASD) is a defect that is usually associated with few symptoms and can be electively repaired with good results. A review of our experience with primum ASD identified a subset of patients characterized by presentation with congestive heart failure (CHF) in the first months of life...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Since the atria are thin-walled structures, most studies that have examined the spread of activation in the atria have assumed that they behave electrophysiologically as a two-dimensional surface. It was the objective of this study to determine whether or not this assumption is true by simultaneously mapping...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.88.1.250
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:The Doppler wire-derived (relative) coronary flow velocity reserve (CVR) that is used to evaluate functional significance of a coronary stenosis is a method performed only by interventional cardiologists. An angiographic method would be useful in the diagnostic catheterization laboratory. For this purpose, w...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/01.CIR.0000074279.44131.DE
更新日期:2003-06-24 00:00:00
abstract::Between 1972 and 1984, 100 consecutive neonates (less than or equal to 30 days old) underwent repair of coarctation of the aorta. Mean (+/- SD) age at operation was 12.0 +/- 8.0 days; mean weight was 3.1 +/- 0.5 kg. Simple coarctation was present in 29 patients (group I), 32 patients had additional ventricular septal ...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1986-09-01 00:00:00
abstract::One hundred consecutive men with a normal ECG at rest had a maximal treadmill test using 14 leads during and post-exercise. Coronary arteriography performed the following day revealed coronary stenoses greater than or equal to 70% in 66 patients. Test results obtained from a V5 lead were compared to different lead com...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.57.1.71
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:In patients with coronary artery disease (CAD), acute thrombosis frequently occurs in coronary arteries with only mild or moderate stenoses. Obesity increases the risk of atherosclerosis, but it is not known whether it also increases the risk of coronary thrombosis. We hypothesized that body mass index (BMI)...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000095270.85646.E8
更新日期:2003-11-04 00:00:00
abstract:BACKGROUND:Depletion of L-arginine (L-arg), the substrate for nitric oxide (NO) synthesis, could be one of the mechanisms responsible for the reduced production of NO and decreased coronary flow (CF) during reperfusion. This, in turn, may adversely affect mechanical function. We aimed to study the benefits of exogenous...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1997-11-04 00:00:00
abstract::Exit block from a parasystolic focus is recognized when automatic discharges fail to become manifest during the excitable phase of the ventricular cycle. In the present study, an apparently complete exit block and a persistently concealed ventricular parasystole (VP) resulted from an exit refractory period (ExRP) long...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.64.1.199
更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:The Ross procedure and aortic homografts have both been shown to have superior hemodynamic performance after valve replacement, but there have been few comparisons. METHODS:Sequential Doppler echocardiograms were performed up to 5 years after aortic valve replacement in 132 patients with the Ross procedure ...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:
更新日期:2002-09-24 00:00:00
abstract::The effects of encainide on ventricular arrhythmia and left ventricular function were studied in 21 patients with chronic, high-grade ventricular arrhythmia using a prospective, 3-month, placebo-controlled, single-blind trial design. Encainide caused a 96% decrease in the average hourly frequency of ventricular premat...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/01.cir.65.6.1134
更新日期:1982-06-01 00:00:00
abstract:BACKGROUND:Plaque disruption and exposure of subendothelial procoagulants such as tissue factor (TF) to circulating factor VII/VIIa (FVII/VIIa) lead to intravascular thrombosis. Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of TF-induced coagulation that binds to factor Xa and the TF-FVIIa catalytic...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.98.11.1051
更新日期:1998-09-15 00:00:00
abstract::Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease, and many believe that diabetes leads to cardiomyopathy. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac dysfunction in the absence of coronary art...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:10.1161/CIRCULATIONAHA.106.679597
更新日期:2007-06-26 00:00:00
abstract:BACKGROUND:Brain natriuretic peptide is a novel natriuretic peptide that is secreted predominantly from the ventricles, and its plasma levels have been shown to be markedly increased in patients with chronic congestive heart failure. This study was designed to examine the plasma levels of brain natriuretic peptide as w...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.88.1.82
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:The metabolic syndrome is associated with increased angiotensin II activity, induction of a proinflammatory and oxidative state, and endothelial dysfunction. We evaluated the ability of irbesartan, an angiotensin receptor blocker, and lipoic acid, an antioxidant, to affect endothelial function and inflammati...
journal_title:Circulation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.CIR.0000153272.48711.B9
更新日期:2005-01-25 00:00:00
abstract:BACKGROUND:Antiplatelet agents presently used in the secondary prevention of cardiovascular disease fail to prevent the majority of cases of recurrent stroke and systemic embolization. An evaluation of the efficacy of new agents is hampered by a lack of in vivo models in humans. Asymptomatic cerebral embolic signals (E...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/01.cir.98.14.1372
更新日期:1998-10-06 00:00:00
abstract::We reviewed 35 patients undergoing resection of a chronic postinfarction left ventricular aneurysm. There was 5.7% operative mortality. Of the long-term survivors, 80% are functional class I or II. Ten patients had postoperative left ventriculograms studied by means of a computerized analysis of endocardial motion usi...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1977-09-01 00:00:00
abstract:BACKGROUND:An effect of diet in determining blood pressure is suggested by epidemiological studies, but the role of specific nutrients is still unsettled. METHODS AND RESULTS:The relation of various nutritional factors with hypertension was examined prospectively among 30,681 predominantly white US male health profess...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.86.5.1475
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:Hypercholesterolemic mice lacking factors required for activation of CD4+ T cells are characterized by reduced development of atherosclerosis. Consequently, it has been assumed that atherosclerosis involves loss of tolerance against modified self-antigens generated in response to hypercholesterolemia and tha...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.118.039288
更新日期:2019-05-28 00:00:00
abstract:BACKGROUND:The extent of the peri-infarct zone by magnetic resonance imaging (MRI) has been related to all-cause mortality in patients with coronary artery disease. This relationship may result from arrhythmogenesis in the infarct border. However, the relationship between tissue heterogeneity in the infarct periphery a...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/CIRCULATIONAHA.106.653568
更新日期:2007-04-17 00:00:00
abstract:BACKGROUND:Little information is available regarding the occurrence of perioperative and late cardiac events in women with vascular disease. The current study was performed to examine whether sex-specific differences exist in these outcomes in a large population of vascular surgery patients and to determine the value o...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.91.4.1044
更新日期:1995-02-15 00:00:00
abstract:BACKGROUND:The purpose of this study was to compare differential effects of a segment of slow conduction during ventricular tachycardia (VT) due to depression of the action potential and electrical uncoupling. METHODS AND RESULTS:In 33 Langendorff-perfused rabbit hearts, a ring of anisotropic left ventricular subepica...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.99.7.949
更新日期:1999-02-23 00:00:00
abstract:BACKGROUND:Demonstration and quantification of site-specific intracoronary administration of compounds has been confined thus far to the experimental animal laboratory. The aim of this study was to describe a scintigraphic method to demonstrate site-specific intracoronary drug delivery in humans. The methods allow on-l...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/01.cir.96.1.154
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Weight loss in obese insulin-resistant but not in insulin-sensitive persons reduces coronary heart disease risk. To what extent changes in gene expression are related to atherosclerosis and cardiovascular function is unknown. METHODS AND RESULTS:We studied the effect of diet restriction-induced weight loss ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000147614.85888.7A
更新日期:2004-11-16 00:00:00
abstract:BACKGROUND:Depressive symptoms have been associated with increased risk of coronary artery disease and poor prognosis among patients with existing coronary artery disease, but whether depressive symptoms specifically influence atherosclerotic progression among such patients is uncertain. METHODS AND RESULTS:The Post-C...
journal_title:Circulation
pub_type: 杂志文章,随机对照试验
doi:10.1161/CIRCULATIONAHA.107.741058
更新日期:2008-05-06 00:00:00
abstract:BACKGROUND:Exertional fatigue, which frequently limits exercise in patients with chronic heart failure, is associated with early anaerobic metabolism in skeletal muscle. The present study was designed to examine the skeletal muscle metabolic response to exercise in this disorder and determine the relation of reduced mu...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.84.4.1597
更新日期:1991-10-01 00:00:00
abstract::Echocardiography was used to study left ventricular size and contraction in 128 patients with isolated aortic valve disease -45 patients with aortic stenosis, 25 with mixed aortic valve disease and 58 with aortic regurgitation. Left ventricular measurements included the end-diastolic internal dimension (LVIDd), mural ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.53.5.860
更新日期:1976-05-01 00:00:00
abstract::Children with congenital aortic stenosis have "excessive" left ventricular hypertrophy with reduced resting systolic wall stress that allows for supernormal ejection performance. If aortic stenosis is uncorrected, this pattern persists until adulthood. The effect of removing the aortic pressure gradient on left ventri...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.78.6.1358
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:CXCL16/SR-PSOX is an interferon-gamma-regulated chemokine and scavenger receptor for oxidized low-density lipoprotein that is expressed in atherosclerotic lesions. Proteolytic cleavage of membrane-bound CXCL16 releases soluble CXCL16, which may promote migration of effector T cells and augment a proatherogen...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.108.806877
更新日期:2009-06-30 00:00:00
abstract::Audible atrial sounds were noted in a patient with congestive cardiomyopathy and atrial fibrillation with slow ventricular rate. Oscillatory motion of similar periodicity as fibrillation waves in the ECG and the sounds in the phonocardiogram was demonstrated in aortic and left ventricular walls, mitral, tricuspid and ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.53.3.569
更新日期:1976-03-01 00:00:00