Concealed ventricular parasystole uncovered in the form of ventricular escapes of variable coupling.

abstract：BACKGROUND:The pulmonary circulation is an important site for the production and clearance of endothelin (ET)-1, a potent vasoactive and mitogenic peptide. Increased plasma ET-1 levels are observed in pulmonary arterial hypertension (PHT) and may contribute to the regulation of pulmonary vascular resistance, as well as...

journal_title：Circulation

authors： Bauer M,Wilkens H,Langer F,Schneider SO,Lausberg H,Schäfers HJ

更新日期：2002-03-05 00:00:00

abstract：BACKGROUND:In this study, we both investigated coronary flow velocity in hypertrophic obstructive cardiomyopathy (HOCM) and tested the hypothesis of differing coronary flow reserve (CFR) of coronary arteries perfusing left ventricular regions with nonuniform myocardial hypertrophy by measuring the relative CFR. METHOD...

journal_title：Circulation

authors： Kyriakidis MK,Dernellis JM,Androulakis AE,Kelepeshis GA,Barbetseas J,Anastasakis AN,Trikas AG,Tentolouris CA,Gialafos JE,Toutouzas PK

更新日期：1997-08-05 00:00:00

abstract：:Background: Vascular smooth muscle cells (VSMCs) show a remarkable phenotypic plasticity allowing acquisition of contractile or synthetic states but critical information is missing about the physiological signals, promoting formation and maintenance of contractile VSMCs in vivo. BMP9 and BMP10 are known to regulate en...

journal_title：Circulation

authors： Wang L,Rice M,Swist S,Kubin T,Wu F,Wang S,Kraut S,Weissmann N,Böttger T,Wheeler M,Schneider A,Braun T

更新日期：2020-12-18 00:00:00

abstract：BACKGROUND:Vasomotor reactivity may contribute to the pathophysiology of ischemic injury. The atherosclerotic vessel may be particularly susceptible to vasoconstriction because of the damaged endothelial layer with resultant loss of vasodilatory factors. While dietary omega 3 fatty acids have been proposed to protect a...

journal_title：Circulation

authors： Malis CD,Leaf A,Varadarajan GS,Newell JB,Weber PC,Force T,Bonventre JV

更新日期：1991-09-01 00:00:00

abstract：:Optimal electrode position for long-term transvenous cardiac pacing is in the apex of the right ventricle. Intracardiac electrograms, surface electrocardiograms, frontal fluoroscopy, lateral roentgenograms, and pacing threshold levels were studied in two groups of patients: One group was comprised of five patients wit...

journal_title：Circulation

authors： Gulotta SJ

更新日期：1970-10-01 00:00:00

abstract：:In this study we extended the characterization of outcome in 1214 medically treated patients with coronary disease by considering nonfatal infarction and death together as ischemic events. At 7 years, the cumulative event rate was 47% (18% for nonfatal infarction as the initial event and 29% for death as the initial e...

journal_title：Circulation

authors： Harris PJ,Lee KL,Harrell FE Jr,Behar VS,Rosati RA

更新日期：1980-10-01 00:00:00

abstract：:To estimate the effect of distance between the electrode and the signal source on the amplitude of the His bundle electrogram (HBE) recorded during open heart surgery, a specially designed probe, containing six pairs of closely spaced (1 mm) electrodes was placed on the endocardial surface of the right atrium such tha...

journal_title：Circulation

authors： Dick M 2nd,Krongrad E,Antar RE,Ross S,Bowman FO Jr,Malm JR,Hoffman BF

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:In the minutes to days after myocardial infarction, endogenous lysis of an occlusive coronary arterial thrombus occurs in most subjects. Compared with those in whom thrombolysis does not occur, those with antegrade flow in the infarct artery have improved left ventricular performance, less left ventricular d...

journal_title：Circulation

authors： Moliterno DJ,Lange RA,Meidell RS,Willard JE,Leffert CC,Gerard RD,Boerwinkle E,Hobbs HH,Hillis LD

更新日期：1993-09-01 00:00:00

abstract：:High frequency notching of the QRS complex is associated with transmural infarction, cardiomyopathies, and ventricular hypertrophy from any cause. The mechanism producing notching is unknown; but the presence of a discrete anatomic lesion is not an essential feature. The hypothesis that notching was produced by activa...

journal_title：Circulation

authors： Vanderark CR,Reynolds EW

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Significant gender-related differences exist in the development of left ventricular hypertrophy (LVH). In addition, administration of 17beta-estradiol (E2) to ovariectomized female mice attenuates the development of LVH, demonstrating an antagonistic role for E2 in this process, although no molecular mechani...

journal_title：Circulation

authors： Babiker FA,De Windt LJ,van Eickels M,Thijssen V,Bronsaer RJ,Grohé C,van Bilsen M,Doevendans PA

更新日期：2004-01-20 00:00:00

abstract：:Carotid artery stenting, compared with carotid endarterectomy, is emerging as an effective and less invasive method of revascularization for extracranial carotid artery stenosis. Carotid stenting is established as the treatment of choice for certain high-risk patient subsets, and ongoing clinical trials are evaluating...

journal_title：Circulation

authors： Roubin GS,Iyer S,Halkin A,Vitek J,Brennan C

更新日期：2006-04-25 00:00:00

abstract：BACKGROUND:Although intercellular adhesion molecule-1 (ICAM-1) is known to be expressed in balloon-injured arteries, it remains unknown whether ICAM-1 plays a role in the progression of intimal hyperplasia (IH) induced by balloon injury. METHODS AND RESULTS:We examined the ICAM-1 expression in rat carotid arteries at ...

journal_title：Circulation

authors： Yasukawa H,Imaizumi T,Matsuoka H,Nakashima A,Morimatsu M

更新日期：1997-03-18 00:00:00

abstract：BACKGROUND:Previous studies suggest that management of ambulatory hemodynamics may improve outcomes in chronic heart failure. We conducted a prospective, observational, first-in-human study of a physician-directed patient self-management system targeting left atrial pressure. METHODS AND RESULTS:Forty patients with re...

journal_title：Circulation

authors： Ritzema J,Troughton R,Melton I,Crozier I,Doughty R,Krum H,Walton A,Adamson P,Kar S,Shah PK,Richards M,Eigler NL,Whiting JS,Haas GJ,Heywood JT,Frampton CM,Abraham WT,Hemodynamically Guided Home Self-Therapy in Severe Hea

更新日期：2010-03-09 00:00:00

abstract：BACKGROUND:Concern that trans-fatty acids formed in the partial hydrogenation of vegetable oils may increase the risk of coronary disease has existed for several decades, but direct evidence on this relation in humans is limited. METHODS AND RESULTS:With a case-control design, we studied the association between intake...

journal_title：Circulation

authors： Ascherio A,Hennekens CH,Buring JE,Master C,Stampfer MJ,Willett WC

更新日期：1994-01-01 00:00:00

abstract：:Balloon dilation angioplasty was attempted in 10 infants and children with severe congenital or operative "venous" obstructions. In five children the obstructions were "vena caval" and followed repair for transposition of the great vessels (four patients) or orthotopic liver transplantation (one patient). In the four ...

journal_title：Circulation

authors： Lock JE,Bass JL,Castaneda-Zuniga W,Fuhrman BP,Rashkind WJ,Lucas RV Jr

更新日期：1984-09-01 00:00:00

abstract：:The outlook for patients with double-outlet right ventricle has improved since the development of corrective operations. Late arrhythmic deaths after successful procedures have been reported; however, the magnitude remains unknown. This study was undertaken to identify the magnitude of late sudden death and the signif...

journal_title：Circulation

authors： Shen WK,Holmes DR Jr,Porter CJ,McGoon DC,Ilstrup DM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The lysyl oxidases are extracellular copper enzymes that initiate the crosslinking of collagens and elastin, 5 human isoenzymes having been characterized so far. The crosslinks formed provide the tensile strength and elastic properties for various extracellular matrices, including vascular walls. We studied ...

journal_title：Circulation

authors： Mäki JM,Räsänen J,Tikkanen H,Sormunen R,Mäkikallio K,Kivirikko KI,Soininen R

更新日期：2002-11-05 00:00:00

abstract：:Adults are living longer, and cardiovascular disease is endemic in the growing population of older adults who are surviving into old age. Functional capacity is a key metric in this population, both for the perspective it provides on aggregate health and as a vital goal of care. Whereas cardiorespiratory function has ...

journal_title：Circulation

authors： Forman DE,Arena R,Boxer R,Dolansky MA,Eng JJ,Fleg JL,Haykowsky M,Jahangir A,Kaminsky LA,Kitzman DW,Lewis EF,Myers J,Reeves GR,Shen WK,American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and St

更新日期：2017-04-18 00:00:00

abstract：:The incidence of valvular heart disease is expected to increase over the next several decades as a large proportion of the US demographic advances into the later decades of life. At the same time, the next several years can be anticipated to bring a broad transition of surgical therapy to minimally invasive (minithora...

journal_title：Circulation

authors： Rosengart TK,Feldman T,Borger MA,Vassiliades TA Jr,Gillinov AM,Hoercher KJ,Vahanian A,Bonow RO,O'Neill W,American Heart Association Council on Cardiovascular Surgery and Anesthesia.,American Heart Association Council on Clinical Card

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The ability of apolipoprotein (apo)A-I to induce regression of preexisting atherosclerotic lesions has not been determined, and a mouse model of atherosclerosis regression has not yet been reported. METHODS AND RESULTS:LDL receptor-deficient mice were fed a western-type diet for 5 weeks to induce atheroscle...

journal_title：Circulation

authors： Tangirala RK,Tsukamoto K,Chun SH,Usher D,Puré E,Rader DJ

更新日期：1999-10-26 00:00:00

abstract：:Trapidil (triazolopyrimidine) possesses activity against platelet-derived growth factor-induced cellular proliferation in vitro and intimal proliferation in vivo. The objective of this study was to determine if trapidil could prevent restenosis in experimentally induced atherosclerotic rabbits. New Zealand White rabbi...

journal_title：Circulation

authors： Liu MW,Roubin GS,Robinson KA,Black AJ,Hearn JA,Siegel RJ,King SB 3rd

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Abnormal coronary endothelial reactivity has been demonstrated in diabetes and is associated with an increased rate of cardiovascular events. Our objectives were to investigate the presence of functional coronary circulatory abnormalities over the full spectrum of insulin resistance and to determine whether ...

journal_title：Circulation

authors： Prior JO,Quiñones MJ,Hernandez-Pampaloni M,Facta AD,Schindler TH,Sayre JW,Hsueh WA,Schelbert HR

更新日期：2005-05-10 00:00:00

abstract：BACKGROUND:The arrhythmia burden in tetralogy of Fallot, types of arrhythmias encountered, and risk profile may change as the population ages. METHODS AND RESULTS:The Alliance for Adult Research in Congenital Cardiology (AARCC) conducted a multicenter cross-sectional study to quantify the arrhythmia burden in tetralog...

journal_title：Circulation

authors： Khairy P,Aboulhosn J,Gurvitz MZ,Opotowsky AR,Mongeon FP,Kay J,Valente AM,Earing MG,Lui G,Gersony DR,Cook S,Ting JG,Nickolaus MJ,Webb G,Landzberg MJ,Broberg CS,Alliance for Adult Research in Congenital Cardiology (AARCC).

更新日期：2010-08-31 00:00:00

abstract：BACKGROUND:A line of block in the right atrium (RA) between the venae cavae is necessary to obtain classic atrial flutter (AFL). We tested the hypothesis that the location of that line of block would determine whether the AFL reentrant circuit would be due to single-loop reentry or figure-of-8 reentry. METHODS AND RES...

journal_title：Circulation

authors： Tomita Y,Matsuo K,Sahadevan J,Khrestian CM,Waldo AL

更新日期：2001-02-20 00:00:00

abstract：:Experimental studies of animals have previously demonstrated the validity of [1-11C]acetate as a tracer of oxidative metabolism for use with positron emission tomography. The present study was undertaken to define in normal human volunteers the relation between myocardial clearance kinetics of [1-11C]acetate, and the ...

journal_title：Circulation

authors： Armbrecht JJ,Buxton DB,Brunken RC,Phelps ME,Schelbert HR

更新日期：1989-10-01 00:00:00

abstract：:Although laparoscopic surgery accounts for >2 million surgical procedures every year, the current preoperative risk scores and guidelines do not adequately assess the risks of laparoscopy. In general, laparoscopic procedures have a lower risk of morbidity and mortality compared with operations requiring a midline lapa...

journal_title：Circulation

authors： Atkinson TM,Giraud GD,Togioka BM,Jones DB,Cigarroa JE

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND:Cardiac dyssynchrony in the failing heart worsens global function and efficiency and generates regional loading disparities that may exacerbate stress-response molecular signaling and worsen cell survival. We hypothesized that cardiac resynchronization (CRT) from biventricular stimulation reverses such molec...

journal_title：Circulation

authors： Chakir K,Daya SK,Tunin RS,Helm RH,Byrne MJ,Dimaano VL,Lardo AC,Abraham TP,Tomaselli GF,Kass DA

更新日期：2008-03-18 00:00:00

abstract：BACKGROUND:Vascular inflammatory lesions from patients with giant-cell arteritis show a remarkable amount of neovascularization, but its clinical implications have never been investigated. METHODS AND RESULTS:To assess the clinical relevance of neovascularization in giant-cell arteritis, angiogenesis was measured in t...

journal_title：Circulation

authors： Cid MC,Hernández-Rodríguez J,Esteban MJ,Cebrián M,Gho YS,Font C,Urbano-Márquez A,Grau JM,Kleinman HK

更新日期：2002-09-24 00:00:00

abstract：BACKGROUND:Estradiol (E2) modulates the kinetics of circulating endothelial progenitor cells (EPCs) and favorably affects neovascularization after ischemic injury. However, the roles of estrogen receptors alpha (ER alpha) and beta (ER beta) in EPC biology are largely unknown. METHODS AND RESULTS:In response to E2, mig...

journal_title：Circulation

authors： Hamada H,Kim MK,Iwakura A,Ii M,Thorne T,Qin G,Asai J,Tsutsumi Y,Sekiguchi H,Silver M,Wecker A,Bord E,Zhu Y,Kishore R,Losordo DW

更新日期：2006-11-21 00:00:00

abstract：:Two patients with supraventricular parasystole (one atrioventricular and one auricular) are reported. In both patients, reentrant extrasystoles appeared to occur as the result of Mobitz type I second-degree entrance block. We believe that when a sinus impulse fell soon after the absolute refractory period of the pathw...

journal_title：Circulation

authors： Kinoshita S,Nakagawa K,Kato N,Nishino T,Tanabe Y

更新日期：1982-01-01 00:00:00