Gold complexes of purine and pyrimidine nucleosides.

abstract：:The polymer-supported oxidovanadium(IV) complex PS-[V(IV)O(sal-dahp)] (2) (PS=chloromethylated polystyrene crosslinked with 5% divinylbenzene, and H3sal-dahp=dibasic pentadentate ligand derived from salicylaldehyde and 1,3-diamino-2-hydroxypropane) was prepared from the corresponding monomeric oxidovanadium(IV) comple...

journal_title：Journal of inorganic biochemistry

authors： Maurya MR,Chaudhary N,Avecilla F,Correia I

更新日期：2015-06-01 00:00:00

abstract：:An overview is given of the results of metal ion-diclofenac interactions. Several complexes have been synthesized at the University of Ioannina. Binuclear complexes, [Cu(L)2(H2O)]2 x 2H2O and [CuL2(S)]2 where S is H2O, EtOH, DMSO, (CH3)2CO and DMF, and mononuclear complexes, [MnL2(H2O)], [FeL2(H2O)2], [CoL2(H2O)2] x 0...

journal_title：Journal of inorganic biochemistry

authors： Kovala-Demertzi D

更新日期：2000-04-01 00:00:00

abstract：:The aerobic redox reaction of Fe(III)bleomycin (Blm) and ascorbate was examined in the absence of DNA and in the presence of 7.5 and 25 calf thymus DNA base pairs per-drug molecule, in order to investigate the effect of DNA binding on the properties of FeBlm activation and DNA strand cleavage. Under these successive c...

journal_title：Journal of inorganic biochemistry

authors： Li W,Antholine WE,Petering DH

更新日期：2002-05-21 00:00:00

abstract：:The reactions of several horse heart myoglobin species with nitrosyl hydride, HNO, derived from Angeli's salt (AS) and Piloty's acid (PA) have been followed by UV-visible, (1)H NMR and EPR spectroscopies. Spectral analysis of myoglobin-derived speciation during the reactions was obtained by using singular value decomp...

journal_title：Journal of inorganic biochemistry

authors： Zapata AL,Kumar MR,Pervitsky D,Farmer PJ

更新日期：2013-01-01 00:00:00

abstract：:A series of new copper (II) complexes with 2-methyl-3-amino(3H)-quinazolin-4-one (MAQ) and various anions (Cl-, Br-, ClO(-)4, NO(-)3, SCN-, and SO(2-)4 was prepared. Their structures and properties were characterized by elemental analysis, IR, UV-Vis and ESR spectroscopy, molar conductivity, and magnetic moment measur...

journal_title：Journal of inorganic biochemistry

authors： Ramadan AM

更新日期：1997-02-15 00:00:00

abstract：:Rats were fed 100 microM aluminum maltolate for one year in their drinking water. Brain aluminum contents have increased 4.2-fold in the aluminum-treated group, whereas no significant changes in the body weight, brain weight, and brain protein content were observed. Long-term aluminum feeding induced apoptosis as asse...

journal_title：Journal of inorganic biochemistry

authors： Huh JW,Choi MM,Lee JH,Yang SJ,Kim MJ,Choi J,Lee KH,Lee JE,Cho SW

更新日期：2005-10-01 00:00:00

abstract：:The glyoxalase system catalyzes the conversion of toxic methylglyoxal to nontoxic d-lactic acid using glutathione (GSH) as a coenzyme. Glyoxalase II (GlxII) is a binuclear Zn enzyme that catalyzes the second step of this conversion, namely the hydrolysis of S-d-lactoylglutathione, which is the product of the Glyoxalas...

journal_title：Journal of inorganic biochemistry

authors： Chen SL,Fang WH,Himo F

更新日期：2009-02-01 00:00:00

abstract：:Interactions of three Ru(II) chlorophenyl terpyridine complexes: [Ru(Cl-Ph-tpy)(en)Cl]Cl (1), [Ru(Cl-Ph-tpy)(dach)Cl]Cl (2) and [Ru(Cl-Ph-tpy)(bpy)Cl]Cl (3) (Cl-Ph-tpy = 4'-(4-chlorophenyl)-2,2':6',2''-terpyridine, en = 1,2-diaminoethane, dach = 1,2-diaminocyclohexane, bpy = 2,2'-bipyridine) with human serum albumin (...

journal_title：Journal of inorganic biochemistry

authors： Masnikosa R,Milutinović MM,Crnolatac I,Tot A,Veličković S,Bojić-Trbojević Ž,Rilak-Simović A

更新日期：2020-07-01 00:00:00

abstract：:Rat kidney selenium (Se)-containing proteins were studied by isotopic labeling with [75Se]selenite or [75Se]selenomethionine via three routes: oral, intraperitoneal injection, and incubation of kidney slices with the isotope. The two major Se-containing proteins in kidney were fractionated and partially characterized....

journal_title：Journal of inorganic biochemistry

authors： Viljoen AJ,Tappel AL

更新日期：1988-08-01 00:00:00

abstract：:Deferriferrioxamine B (H3DFB) is a linear trihydroxamic acid siderophore with molecular formula NH2(CH2)5[N(OH)C(O)(CH2)2C(O)NH(CH2)5]2N(OH)C(O)CH3 that forms a kinetically and thermodynamically stable complex with iron(III), ferrioxamine B. Under the conditions of our study (pH = 4.30, 25 degrees C), ferrioxamine B, ...

journal_title：Journal of inorganic biochemistry

authors： Monzyk B,Crumbliss AL

更新日期：1983-08-01 00:00:00

abstract：:Supranutritional selenium (Se) intake and high serum Se levels have been associated epidemiologically with increased risk for type 2 diabetes, suggesting adverse effects of dietary Se compounds and/or antioxidant selenoenzymes on the sensitivity of target tissues for insulin. Here, we compared the capability of inorga...

journal_title：Journal of inorganic biochemistry

authors： Pinto A,Speckmann B,Heisler M,Sies H,Steinbrenner H

更新日期：2011-06-01 00:00:00

abstract：:The chemical structures of the pentavalent antimonial drugs, meglumine antimonate (MA) and sodium stibogluconate (SSG), were re-evaluated using electrospray ionization mass spectrometry (ESI-MS) and osmolarity measurements. Both MA and SSG were found to contain 1:1, 1:2, 2:2 and 2:3 Sb(V)-ligand complexes. ESI-MS anal...

journal_title：Journal of inorganic biochemistry

authors： Frézard F,Martins PS,Barbosa MC,Pimenta AM,Ferreira WA,de Melo JE,Mangrum JB,Demicheli C

更新日期：2008-04-01 00:00:00

abstract：:Iron overload can act as catalyst for the formation of free radicals, which may promote oxidant-mediated breast carcinogenesis. However, the association between iron and breast cancer has not been comprehensively elucidated. In this study, we found that iron overload upregulated the inflammatory cytokine interleukin-6...

journal_title：Journal of inorganic biochemistry

authors： Cheng M,Liu P,Xu LX

更新日期：2020-09-01 00:00:00

abstract：:Citrate occurs at about 0.1 mM in blood plasma and is the most likely small molecule plasma binder of both Al3+ and Fe3+. This paper assesses published stability constants for citrate binding to each metal ion. From pH 2 to 5 Al3+ forms a neutral complex with citrate that may be absorbed into the body in the upper reg...

journal_title：Journal of inorganic biochemistry

authors： Martin RB

更新日期：1986-10-01 00:00:00

abstract：:Vanadium compounds have arisen as potential therapeutic agent for the treatment of cancers over the past decades. A few studies suggested that vanadyl complexes may discriminate between the cancerous and the normal cells. Here, we reported the investigation on the pro-apoptotic effect and the underlying mechanism of b...

journal_title：Journal of inorganic biochemistry

authors： Zhang Y,Wang L,Zeng K,Wang K,Yang X

更新日期：2018-11-01 00:00:00

abstract：:Signal transduction in plants determines their successful adaptation to diverse stress factors. Our group employed suspension cells to study the phosphoinositide pathway, which is triggered by aluminium stress. We investigated about members of the PI-specific phospholipase C (PLC) family and evaluated their transcript...

journal_title：Journal of inorganic biochemistry

authors： González-Mendoza VM,Sánchez-Sandoval ME,Munnik T,Hernández-Sotomayor SMT

更新日期：2020-03-01 00:00:00

abstract：:Three new platinum(II) complexes with pendent morpholine were synthesized, namely complex 1 ([Pt(L)Cl]CF3SO3), complex 2 ([Pt(L)(NH3)](CF3SO3)2) and complex 3 ([Pt(L)(PPh3)](CF3SO3)2), where L = 4'-[4-(4-morpholinobutyloxy)phenyl]-2,2':6',2″-terpyridine and PPh3 = triphenylphosphine. The detailed molecular structures ...

journal_title：Journal of inorganic biochemistry

authors： Chai K,Kuang W,Lan Z,Zhang L,Jiang Y,Han T,Niu J,Wang J,Duan X

更新日期：2019-03-01 00:00:00

abstract：:The nitrophorins (NP) of the adult blood-sucking insect Rhodnius prolixus fall into two pairs based on sequence identity (NP1,4 (90%) and NP2,3 (79%)), which differ significantly in the size of side chains of residues which contact the heme. These residues include those in the distal pocket of NP2 (I120) and NP1 (T121...

journal_title：Journal of inorganic biochemistry

authors： Shokhireva TK,Berry RE,Zhang H,Shokhirev NV,Walker FA

更新日期：2011-09-01 00:00:00

abstract：:The effect of pH on the X-band electron paramagnetic resonance (EPR) spectrum of ferrous nitrosylated human adult tetrameric hemoglobin (HbNO) as well as of ferrous nitrosylated monomeric alpha- and beta-chains has been investigated, at -163 degrees C. At pH 7.3, the X-band EPR spectrum of tetrameric HbNO and ferrous ...

journal_title：Journal of inorganic biochemistry

authors： Ascenzi P,Bocedi A,Fasano M,Gioia M,Marini S,Coletta M

更新日期：2005-05-01 00:00:00

abstract：:Aggregation of amyloid β-proteins (Aβ) induced by Cu2+ is a crucial element in the pathogenesis of Alzheimer's disease (AD), and cerebral acidosis is a common complication of AD. Under mildly acidic conditions, Cu2+-Aβ species have higher tendency to generate neurotoxic aggregates. Hence it is of significance to devel...

journal_title：Journal of inorganic biochemistry

authors： Xie B,Liu F,Dong X,Wang Y,Liu XM,Sun Y

更新日期：2017-06-01 00:00:00

abstract：:The synthesis and characterization of ruthenium compounds of the type [RuCl(2)(NO)(dppp)(L)]PF(6) [dppp=1,3-bis(diphenylphosphino)propane; L=pyridine, 4-methylpyridine, 4-phenylpyridine and dimethyl sulfoxide] are described. The complexes were characterized by elemental analysis, UV/Vis and infrared spectroscopy, cycl...

journal_title：Journal of inorganic biochemistry

authors： Golfeto CC,Von Poelhsitz G,Selistre-de-Araújo HS,de Araujo MP,Ellena J,Castellano EE,Lopes LG,Moreira IS,Batista AA

更新日期：2010-05-01 00:00:00

abstract：:In order to widen our knowledge on antitumour trans-[PtCl2(iminoether)2] complexes, we have synthesised two new derivatives, trans-[PtCl2¿E-HN = C(OEt)Me¿2] (1) and trans-[PtCl2¿Z-HN = C(OEt)Me¿2] (2), which differ in the configuration of the iminoether ligands. Isomer 1 showed an in vitro cytotoxicity similar to that...

journal_title：Journal of inorganic biochemistry

authors： Coluccia M,Nassi A,Boccarelli A,Giordano D,Cardellicchio N,Locker D,Leng M,Sivo M,Intini FP,Natile G

更新日期：1999-10-01 00:00:00

abstract：:The propensity of a large number of metal ions to induce cooperative conformational or structural transitions in double-stranded poly d(G-C) was assessed by UV and CD spectrometry. This ability was seen to be an intrinsic property of most metal ions. The observed (metal ion)/(polydeoxynucleotide) mole ratio calculated...

journal_title：Journal of inorganic biochemistry

authors： Rossetto FE,Nieboer E

更新日期：1994-05-15 00:00:00

abstract：:The acsABCDE genes in the Clostridium thermoaceticum genome are used for autotrophic acetyl-CoA synthesis using the Wood-Ljungdahl pathway. A 2.8-kb region between acsC and acsD was cloned and sequenced. Two open reading frames, orf7 (approximately 1.9 kb) and acsF (approximately 0.7 kb) were identified. orf7 appears ...

journal_title：Journal of inorganic biochemistry

authors： Loke HK,Lindahl PA

更新日期：2003-01-01 00:00:00

abstract：:A binuclear complex [(phen)Cu(mu-bipp)Cu(phen)](ClO(4))(4), where phen=1,10-phenanthroline and bipp=2,9-bis(2-imidazo[4,5-f][1,10]phenanthroline)-1,10-phenanthroline, has been synthesized and its interaction with calf-thymus DNA in the buffer containing 5mM Tris and 50mM NaCl has been studied by means of electronic ab...

journal_title：Journal of inorganic biochemistry

authors： Wu JZ,Yuan L,Wu JF

更新日期：2005-11-01 00:00:00

abstract：:We have synthesised the complex [Pt(CH(3)SCH(2)CH(2)SCH(3))(5'-GMP-N7)(2)].6H(2)O (1), where 5'-GMP is 5'-guanosine monophosphate, and determined its X-ray crystal structure. Pt(II) adopts a square-planar geometry in which the bases are coordinated head-to-tail (HT) in the Delta configuration. The nucleotide conformat...

journal_title：Journal of inorganic biochemistry

authors： Djuran MI,Milinkovic SU,Habtemariam A,Parsons S,Sadler PJ

更新日期：2002-02-01 00:00:00

abstract：:The synthesis, crystal structures, physicochemical properties and complex formation constants of [Cu(phen)(2)(L)](ClO(4))(2) complexes, where phen is 1,10-ortho-phenanthroline and L is a series of substituted imidazolidine-2-thione, have been studied. Single crystal X-ray diffraction revealed a distorted trigonal-bipy...

journal_title：Journal of inorganic biochemistry

authors： Pivetta T,Cannas MD,Demartin F,Castellano C,Vascellari S,Verani G,Isaia F

更新日期：2011-03-01 00:00:00

abstract：:The reaction of aqueous native DNA (calf thymus) with the solvated organotin(IV) species [(CH3)2SnCl2(C2H5OH)n], as well as with [(CH3)2Sn(OH)(H2O)n]+ and (CH3)2Sn(OH)2 (i.e., the hydrolysis products of aqueous (CH3)2SnCl2 at pH approximately 5 and pH approximately 7.4 respectively), was investigated by 119Sn Mössbaue...

journal_title：Journal of inorganic biochemistry

authors： Barbieri R,Silvestri A

更新日期：1991-01-01 00:00:00

abstract：:Iron is frequently a growth-limiting nutrient due to its propensity to interact with oxygen to form insoluble precipitates and, therefore, biological systems have evolved specialized uptake mechanisms to obtain this essential nutrient. Many pathogenic bacteria are capable of obtaining stringently sequestered iron from...

journal_title：Journal of inorganic biochemistry

authors： Beasley FC,Heinrichs DE

更新日期：2010-03-01 00:00:00

abstract：:To identify regulatory elements in the rat selenoprotein W (SeW) promoter, 2090, 1265, 741, and 404 base pair truncations of genomic DNA lying immediately upstream of the SeW coding sequence were cloned into a luciferase reporter vector (pGL3-Basic from Promega, Madison, WI, USA). 3656 and 406 base pair mouse SeW prom...

journal_title：Journal of inorganic biochemistry

authors： Hooven LA,Vorachek WR,Bauman AB,Butler JA,Ream LW,Whanger PD

更新日期：2005-10-01 00:00:00