Activation of monoamine oxidase isotypes by prolonged intake of aluminum in rat brain.

abstract：:Metals such as CuI and FeII generate hydroxyl radical (.OH) by reducing endogenous hydrogen peroxide (H2O2). Because antioxidants can ameliorate metal-mediated oxidative damage, we have quantified the ability of glutathione, a primary intracellular antioxidant, and other biological sulfur-containing compounds to inhib...

journal_title：Journal of inorganic biochemistry

authors： Battin EE,Brumaghim JL

更新日期：2008-12-01 00:00:00

abstract：:Quantitative characterization of metalloproteins at molecular and atomic levels generally requires tens of milligrams of highly purified samples, a situation frequently challenged by problems in generating unmodified native forms. A variety of affinity tags, such as the popular poly-histidine tag, have been developed ...

journal_title：Journal of inorganic biochemistry

authors： Wijekoon CJK,Ukuwela AA,Wedd AG,Xiao Z

更新日期：2016-09-01 00:00:00

abstract：:The synthesis, crystal structures, physicochemical properties and complex formation constants of [Cu(phen)(2)(L)](ClO(4))(2) complexes, where phen is 1,10-ortho-phenanthroline and L is a series of substituted imidazolidine-2-thione, have been studied. Single crystal X-ray diffraction revealed a distorted trigonal-bipy...

journal_title：Journal of inorganic biochemistry

authors： Pivetta T,Cannas MD,Demartin F,Castellano C,Vascellari S,Verani G,Isaia F

更新日期：2011-03-01 00:00:00

abstract：:Rat liver metallothionein contains two domains, each of which enfolds a separate metal-thiolate cluster. The binding stoichiometry of these clusters depends on the particular metal ion bound. In the aminoterminal beta domain the cluster can accommodate either three Cd(II) ions or six Cu(I) ions. The Cd ions are known ...

journal_title：Journal of inorganic biochemistry

authors： George GN,Winge D,Stout CD,Cramer SP

更新日期：1986-07-01 00:00:00

abstract：:[Au(dppz)(2)]Cl(3) was synthesized by the reaction of HAuCl(4) in excess of the dypirido[3,2-a: 2,3-c]phenazine (dppz) ligand. This complex was characterized by elemental analysis, fast atom bombardment (FAB) mass, NMR, UV-visible and IR spectroscopies. DNA-gold complex interactions were studied by spectroscopic titra...

journal_title：Journal of inorganic biochemistry

authors： Navarro M,Hernández C,Colmenares I,Hernández P,Fernández M,Sierraalta A,Marchán E

更新日期：2007-01-01 00:00:00

abstract：:Bacteria have developed multiple resistance mechanisms against the most used antibiotics. In particular, zinc-dependent metallo-β-lactamase producing bacteria are a growing threat, and therapeutic options are limited. Zinc chelators have recently been investigated as metallo-β-lactamase inhibitors, as they are often a...

journal_title：Journal of inorganic biochemistry

authors： La Piana L,Viaggi V,Principe L,Di Bella S,Luzzaro F,Viale M,Bertola N,Vecchio G

更新日期：2021-02-01 00:00:00

abstract：:Nanosized flower-like ZnO was synthesized by a simple hydrothermal method which is a convenient, environment friendly, inexpensive and efficient process. Raman spectroscopy, X-ray diffraction (XRD) and scanning electron microscope (SEM) were used to confirm the material structure and the crystallite microstructure. Th...

journal_title：Journal of inorganic biochemistry

authors： Liu YL,Yang YH,Yang HF,Liu ZM,Shen GL,Yu RQ

更新日期：2005-10-01 00:00:00

abstract：:Copper based nanoparticles (Cu-based NPs) of different compositions and sizes have been hydrothermally synthesized by varying the reaction time in the presence of the biocompatible surfactants polyoxyethylene (20) sorbitan laurate (Tween 20) and polyethylene glycol 8000 (PEG 8000). Effective control of the above synth...

journal_title：Journal of inorganic biochemistry

authors： Giannousi K,Lafazanis K,Arvanitidis J,Pantazaki A,Dendrinou-Samara C

更新日期：2014-04-01 00:00:00

abstract：:In order to widen our knowledge on antitumour trans-[PtCl2(iminoether)2] complexes, we have synthesised two new derivatives, trans-[PtCl2¿E-HN = C(OEt)Me¿2] (1) and trans-[PtCl2¿Z-HN = C(OEt)Me¿2] (2), which differ in the configuration of the iminoether ligands. Isomer 1 showed an in vitro cytotoxicity similar to that...

journal_title：Journal of inorganic biochemistry

authors： Coluccia M,Nassi A,Boccarelli A,Giordano D,Cardellicchio N,Locker D,Leng M,Sivo M,Intini FP,Natile G

更新日期：1999-10-01 00:00:00

abstract：:The effect of the Cu(II)-mitoxantrone complex on the DNA synthesis of HL-60 human leukemia cells has been studied by the technique of isotopic liquid scintillation. The results indicated that the complex shows a stronger ability to inhibit DNA synthesis of the tumor cells, and thus it may become a better antitumor dru...

journal_title：Journal of inorganic biochemistry

authors： Yang P,Wang H,Gao F,Yang B

更新日期：1996-05-01 00:00:00

abstract：:Two new complexes [(Etdpa)MnCl(2)] and [(Adpa)Mn(Cl)(H(2)O)] (Etdpa = ethyl bis(2-pyridylmethyl)amino-2-propionate; Adpa = bis(2-pyridylmethyl)amino-2-propionic acid) were synthesized and characterized by spectral methods. The crystal structure of [(Etdpa)MnCl(2)] shows that the Mn(II) atom is coordinated by three N a...

journal_title：Journal of inorganic biochemistry

authors： Qiu-Yun C,Dong-Fang Z,Juan H,Wen-Jie G,Jing G

更新日期：2010-11-01 00:00:00

abstract：:The conformation of poly[d(T-G).d(C-A)] in aqueous solution (0.1 M NaClO4, 5 mM cacodylic acid buffer, pH 6.9) was studied by circular dichroism (CD) spectroscopy in the ultraviolet. The conformation of the polynucleotide, as reflected by its chiroptical signature, changes in a highly cooperative fashion in the presen...

journal_title：Journal of inorganic biochemistry

authors： Gruenwedel DW,Cruikshank MK

更新日期：1991-07-01 00:00:00

abstract：:Two new homo- and hetero-dinuclear complexes, [Cu(2)L(im)](ClO(4))(3)4H(2)O (1) and [CuZnL(im)](ClO(4))(3)4H(2)O (2) (where Im=1H-1midazole and L=3, 6, 9, 16, 19, 22-hexaaza-6, 19-bis(1H-imidazol-4-ylmethyl)tricycle[22, 2, 2, 2(11,14)]triaconta-1, 11, 13, 24, 27, 29-hexaene) were synthesized and characterized as model...

journal_title：Journal of inorganic biochemistry

authors： Yuan Q,Cai K,Qi ZP,Bai ZS,Su Z,Sun WY

更新日期：2009-08-01 00:00:00

abstract：:HIF prolyl-4-hydroxylase 2 (PHD2) is a non-heme Fe, 2-oxoglutarate (2OG) dependent dioxygenase that regulates the hypoxia inducible transcription factor (HIF) by hydroxylating two conserved prolyl residues in N-terminal oxygen degradation domain (NODD) and C-terminal oxygen degradation domain (CODD) of HIF-1α. Prior s...

journal_title：Journal of inorganic biochemistry

authors： Pektas S,Knapp MJ

更新日期：2013-09-01 00:00:00

abstract：:With its about 100,000 three-dimensional structures, the Protein Data Bank is a copious source of information: it contains also some hundreds of structures of macromolecules complexed with lanthanide cations, which are examined here. These cations, which are found in a wide variety of protein types, were introduced to...

journal_title：Journal of inorganic biochemistry

authors： Djinovic-Carugo K,Carugo O

更新日期：2015-02-01 00:00:00

abstract：:Hexacyanochromate ion, (Cr(CN)6)3-, was applied to ribonuclease T1 (RNase T1), which specifically cleaves RNA chains at guanylic acid residues. From kinetic studies, this anion was shown to bind to the active site of RNase T1 as a competitive inhibitor. Therefore, the line broadening effect of NMR resonances due to bi...

journal_title：Journal of inorganic biochemistry

authors： Inagaki F,Shimada I

更新日期：1986-10-01 00:00:00

abstract：:The reaction between cyanide and aurothiomalate (Autm) has been studied by 1H and 13C NMR spectroscopy and by uv spectroscopy. At cyanide:Autm ratios greater than or equal to 2, aurocyanide, [Au(CN)2]-, is the sole product but was also produced at lower ratios. Two intermediates were also identified. These were a mixe...

journal_title：Journal of inorganic biochemistry

authors： Graham GG,Bales JR,Grootveld MC,Sadler PJ

更新日期：1985-11-01 00:00:00

abstract：:The dynamics of iron nuclei in the condensates obtained by interaction of Fe(III) with DNA, Fe(III)(DNA monomer)(2), have been investigated by variable temperature (57)Fe Mössbauer spectroscopy. Studies were effected on gel and freeze-dried samples, obtaining nearly coincident values of the parameters isomer shift and...

journal_title：Journal of inorganic biochemistry

authors： Trotta A,Barbieri Paulsen A,Silvestri A,Ruisi G,Assunta Girasolo M,Barbieri R

更新日期：2002-01-01 00:00:00

abstract：:A large number of proteins contain bound zinc ions. These zinc ions are frequently coordinated by a combination of histidine and cysteine residues. In addition to atoms that coordinate directly to the zinc ions, these side chains have groups that can donate or accept hydrogen bonds from other groups. These secondary i...

journal_title：Journal of inorganic biochemistry

authors： Namuswe F,Berg JM

更新日期：2012-06-01 00:00:00

abstract：:In a quest for more effective radiopharmaceuticals for pain palliation of metastatic bone cancer, this paper relates results obtained with 166Ho and 153Sm complexed to the bone seeking phosphonate, N,N-dimethylenephosphonate-1-hydroxy-4-aminopropylidenediphosphonate (APDDMP). APDDMP is synthesised from the known bone ...

journal_title：Journal of inorganic biochemistry

authors： Zeevaart JR,Jarvis NV,Louw WK,Jackson GE

更新日期：2001-01-01 00:00:00

abstract：:Three novel copper(II) compounds of formulas {[Cu(Phen)(Ala)]·NO3·H2O}n (1), {[Cu(Phen)(Ala)]·NO3}n (2) and [Cu(Ala)2]n (3) have been synthesized and determined by X-ray diffraction. 1 and 2 are shown in one dimensional long-chain chiral structures, and 3 is a two dimensional checkerboard-type structure. Both 1 and 2 ...

journal_title：Journal of inorganic biochemistry

authors： Zhang WC,Tang X,Lu X

更新日期：2016-03-01 00:00:00

abstract：:The tyrosine kinase inhibitor imatinib is successfully used in the treatment of chronic myeloid leukemia, but the occurrence of resistance phenomena can significantly limit therapeutic impact. Imatinib shows synergistic effects with cisplatin, suggesting that the coadministration of different cytostatics might reestab...

journal_title：Journal of inorganic biochemistry

authors： Ott I,Abraham A,Schumacher P,Shorafa H,Gastl G,Gust R,Kircher B

更新日期：2006-11-01 00:00:00

abstract：:New complexes of the type [Cr(INH)2Cl2]Cl.2H2O, VO(INH)2Cl2 and TiO(INH)2Cl, where INH = isonicotinic acid hydrazide, have been prepared. The complexes were characterized by infrared and UV-vis spectroscopy, proton nuclear magnetic resonance (NMR) and elemental analyses, molar conductivity and x-ray powder diffraction...

journal_title：Journal of inorganic biochemistry

authors： Pin Y,Zhang XP

更新日期：1989-09-01 00:00:00

abstract：:The copper(II)-5-fluorosalicylic acid system was investigated in water and 50 v/v% water-methanol mixture by pH potentiometry combined with UV-vis spectrophotometry, and by the two-dimensional ESR simulation method, respectively. The data revealed that the stable paramagnetic mono- and bis(salicylato) copper(II) compl...

journal_title：Journal of inorganic biochemistry

authors： Szabó-Plánka T,Gyurcsik B,Nagy NV,Rockenbauer A,Sípos R,Sima J,Melník M

更新日期：2008-01-01 00:00:00

abstract：:The effect of inositol hexakisphosphate (IHP) on the spectroscopic (EPR and absorbance) properties of the nitric oxide derivative of ferrous naturally glycated human hemoglobin HbA1c (HbA1cNO) has been investigated quantitatively. The results obtained show that 1) both in the absence and presence of IHP, the EPR and a...

journal_title：Journal of inorganic biochemistry

authors： Ascenzi P,Desideri A,Amiconi G,Bertollini A,Bolognesi M,Castagnola M,Coletta M,Brunori M

更新日期：1988-09-01 00:00:00

abstract：:The cytotoxic potency of a series of triphenyltin(IV) compounds of general composition [Ph3Sn(Ln)] (1-6) has been probed in vitro employing MDA-MB-231 (human breast cancer) and HeLa (human cervical cancer) cell lines, where Ln=L1-3; isomeric 2/3/4-{(E)-2-[4-(dimethylamino)phenyl]diazenyl}benzoates and L4-6 are their c...

journal_title：Journal of inorganic biochemistry

authors： Basu Baul TS,Dutta D,Duthie A,Prasad R,Rana NK,Koch B,Tiekink ERT

更新日期：2017-08-01 00:00:00

abstract：:The interaction of V(IV)O-salts as well as of a few V(IV)O(carrier)n complexes with human serum transferrin (hTF) is studied focusing on the determination of the nature and stoichiometry of the binding of V(IV)O(2+) to hTF, as well as whether the conformation of hTF upon binding to V(IV)O(2+) or to its complexes is ch...

journal_title：Journal of inorganic biochemistry

authors： Mehtab S,Gonçalves G,Roy S,Tomaz AI,Santos-Silva T,Santos MF,Romão MJ,Jakusch T,Kiss T,Pessoa JC

更新日期：2013-04-01 00:00:00

abstract：:It has been recently reported that pyrophosphate, tri-polyphosphate, ATP and analogous ligands considerably decrease the yield of hydroxyl radicals by the Fenton reaction under conditions where [H(2)O(2)]>[Fe(II)L(n)]. It was suggested that this effect is due to the slowing down of the Fenton reaction by these ligands...

journal_title：Journal of inorganic biochemistry

authors： Rachmilovich-Calis S,Masarwa A,Meyerstein N,Meyerstein D

更新日期：2011-05-01 00:00:00

abstract：:The 1,7-diacetate-4,10-diacetamide substituted 1,4,7,10-tetraazacyclododecane structural unit is common to several responsive Magnetic Resonance Imaging (MRI) contrast agents (CAs). While some of these complexes (agents capable of sensing fluctuations in Zn2+, Ca2+ etc. ions) have already been tested in vivo, the deta...

journal_title：Journal of inorganic biochemistry

authors： Tircsó G,Tircsóné Benyó E,Garda Z,Singh J,Trokowski R,Brücher E,Sherry AD,Tóth É,Kovács Z

更新日期：2020-05-01 00:00:00

abstract：:Selenium (Se) influences the levels of selenoprotein W (SelW) in mammals. However, little is known about the pattern of SelW expression in the pancreatic tissue of birds. To investigate the effects of dietary Se levels on the expression of SelW mRNA in the pancreatic tissue of birds, one-day-old chickens were randomly...

journal_title：Journal of inorganic biochemistry

authors： Wang R,Sun B,Zhang Z,Li S,Xu S

更新日期：2011-09-01 00:00:00