Senile parkinsonism, a study of current treatment.

Abstract:

:In a survey of all 2069 in-patients at 14 geriatric centres, 249 patients were found to have received drugs for the treatment of parkinsonism. There was a wide variation in point prevalence which varied from 4.6% to 22.6% between centres. Levodopa, usually in combination with a decarboxylase inhibitor, was the most frequently prescribed drug. Compared with the recommendations for its use in Parkinson's diseases, over 75% of patients received inadequate and widely spaced doses. Furthermore, dopamine antagonists were concurrently prescribed to one-third of patients who received levodopa. There was a high incidence of treatment failure (30%), and a low incidence of drug-induced dyskinesia (3%). Dementia was closely associated with the onset of parkinsonism. These findings suggest that many of these patients did not have Parkinson's disease but rather rigid-akinetic syndromes associated with degenerative brain disease. The treatment of parkinsonism in the elderly requires reevaluation.

journal_name

Age Ageing

journal_title

Age and ageing

authors

White NJ,Barnes TR

doi

10.1093/ageing/10.2.81

subject

Has Abstract

pub_date

1981-05-01 00:00:00

pages

81-6

issue

2

eissn

0002-0729

issn

1468-2834

journal_volume

10

pub_type

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