Plasma leptin levels are not predictive of dementia in patients with mild cognitive impairment.

abstract：:This study describes a survey of 256 informal carers and elderly people they support, and examines the impact of the caring role upon quality of life. Carers reported that many aspects of their physical and mental health as well as their social and family lives were affected by their caring. For many the caring activi...

journal_title：Age and ageing

authors： Jones DA,Peters TJ

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:in a secondary analysis of a randomised controlled trial, we investigated whether 6 months of music-based multitask training had beneficial effects on cognitive functioning and mood in older adults. METHODS:134 community-dwellers aged ≥65 years at increased risk for falling were randomly assigned to either ...

journal_title：Age and ageing

authors： Hars M,Herrmann FR,Gold G,Rizzoli R,Trombetti A

更新日期：2014-03-01 00:00:00

abstract：:Four hundred and fifty patients aged 75 years or older were followed up after discharge from an accident and emergency department. Forty-three per cent of all patients experienced some loss of functional independence. A small number, 5.6%, were readmitted to hospital within 14 days. This group were significantly less ...

journal_title：Age and ageing

authors： Rowland K,Maitra AK,Richardson DA,Hudson K,Woodhouse KW

更新日期：1990-11-01 00:00:00

abstract：:The effect of leukoaraiosis or white matter low attenuation (WMLA) on cognitive function is not fully understood. We compared the neuropsychological performance of 37 Alzheimer's disease patients with WMLA on CT brain scans with a similar group of 31 Alzheimer's disease patients with no evidence of white matter lesion...

journal_title：Age and ageing

authors： Amar K,Bucks RS,Lewis T,Scott M,Wilcock GK

更新日期：1996-11-01 00:00:00

abstract：Background:pain is prevalent in frail older adults; however, the association of pain and frailty has not been evaluated yet by a systematic assessment of prospective longitudinal studies. Objective:we aimed to assess the association of persistent pain as a risk factor for frailty incidence, using data from longitudina...

journal_title：Age and ageing

authors： Saraiva MD,Suzuki GS,Lin SM,de Andrade DC,Jacob-Filho W,Suemoto CK

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. METHODS:We reviewed the 2008 STOPP/START criteria to add new evidence-based...

journal_title：Age and ageing

authors： O'Mahony D,O'Sullivan D,Byrne S,O'Connor MN,Ryan C,Gallagher P

更新日期：2015-03-01 00:00:00

abstract：Background:there is growing consensus around the importance of population level approaches which seek to improve public knowledge and awareness of dementia. Aim:to assess knowledge of the relationship between dementia and ageing, and of the risk and protective factors associated with it, among the general public in Ir...

journal_title：Age and ageing

authors： Glynn RW,Shelley E,Lawlor BA

更新日期：2017-09-01 00:00:00

abstract：:Spasticity is common after stroke and other neurological conditions and causes considerable limitations of movement, activities of daily living and participation. Interaction with other components of the upper motor neurone syndrome (UMNS) and the heterogeneity of patients' presentations together with limited tools fo...

journal_title：Age and ageing

authors： Graham LA

更新日期：2013-07-01 00:00:00

abstract：:Postural control is no longer considered simply a summation of static reflexes but, rather, a complex skill based on the interaction of dynamic sensorimotor processes. The two main functional goals of postural behaviour are postural orientation and postural equilibrium. Postural orientation involves the active alignme...

journal_title：Age and ageing

authors： Horak FB

更新日期：2006-09-01 00:00:00

abstract：:The aim of this prospective study was to investigate whether an immunological double faecal occult blood test (Fecatwin-S/FECA-EIA) can be used in screening patients with symptoms suggestive of colonic or rectal origin in primary health care. Altogether 523 patients were referred to the study by general practitioners....

journal_title：Age and ageing

authors： Kemppainen M,Häkkinen I,Räihä I,Pomoell R,Sourander L

更新日期：1994-09-01 00:00:00

abstract：:A random sample of 241 patients from General Practice registers in London were interviewed to assess alcohol consumption, cognitive impairment, depression and other factors. Fifty-one per cent of men and 22% of women reported use of alcohol in the previous 3 months. No significant association was found between reporte...

journal_title：Age and ageing

authors： Iliffe S,Haines A,Booroff A,Goldenberg E,Morgan P,Gallivan S

更新日期：1991-03-01 00:00:00

abstract：:In this study we examine whether the introduction of a clerking pro forma improves the completeness of the recording of the management of stroke patients and we review methodological issues important in this type of audit. We prospectively identified 244 consecutive stroke patients before and after the introduction of...

journal_title：Age and ageing

authors： Davenport RJ,Dennis MS,Warlow CP

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:To examine how improved attention to nutritional status and dietary intake, achieved through the employment of dietetic assistants (DAs), will affect postoperative clinical outcome among elderly women with hip fracture. DESIGN:Open prospective randomised controlled trial, comparing conventional nursing care ...

journal_title：Age and ageing

authors： Duncan DG,Beck SJ,Hood K,Johansen A

更新日期：2006-03-01 00:00:00

abstract：:Clinical assessments have to be used in epidemiological studies in the absence of more objective means of establishing diagnosis or recording events in the natural history of disease. This requires the standardization of definition, technique and interpretation as a means of reducing observer variability in clinical e...

journal_title：Age and ageing

authors： Garraway WM,Akhtar AJ,Gore SM,Prescott RJ,Smith RG

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:in the UK, two-thirds of patients in general hospitals are older than 70, of whom half have dementia or delirium or both. Our objective was to explore doctors, nurses and allied health professionals' perceptions of their preparation to care for confused older patients on general hospital wards....

journal_title：Age and ageing

authors： Griffiths A,Knight A,Harwood R,Gladman JR

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:the 16-item Falls Efficacy Scale-International (FES-I) has been shown to have excellent reliability and construct validity. However, for practical and clinical purposes, a shortened version of the FES-I would be useful. OBJECTIVE:to develop and validate a shortened version of FES-I while preserving good psy...

journal_title：Age and ageing

authors： Kempen GI,Yardley L,van Haastregt JC,Zijlstra GA,Beyer N,Hauer K,Todd C

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Some patients may have medication-related risk factors only identified by home visits, but the extent to which those risk factors are associated with poor health outcomes remains unclear. OBJECTIVE:To determine the association between medication-related risk factors and poor patient health outcomes from obs...

journal_title：Age and ageing

authors： Sorensen L,Stokes JA,Purdie DM,Woodward M,Roberts MS

更新日期：2005-11-01 00:00:00

abstract：:Plasma Human Growth Hormone (HGH) was raised in a patient with bronchial carcinoma and hypertrophic pulmonary osteoarthropathy before radiotherapy to the tumour. Though the soft-tissue swelling and pain of hypertrophic osteoarthropathy disappeared two to three weeks after radiotherapy to the carcinoma the HGH plasma l...

journal_title：Age and ageing

authors： Mukherjee SK

更新日期：1975-05-01 00:00:00

abstract：Background:fear of falling (FOF) is a major health concern among community-dwelling older adults that could restrict mobility. Objective:to examine the association of FOF with life-space mobility (i.e. the spatial area a person moves through in daily life) of community-dwelling older adults from five diverse sites. M...

journal_title：Age and ageing

authors： Auais M,Alvarado B,Guerra R,Curcio C,Freeman EE,Ylli A,Guralnik J,Deshpande N

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:polypharmacy is an important risk factor for falls, but recent studies suggest only when including medications associated with increasing the risk of falls. DESIGN:a prospective, population-based cohort study. SUBJECTS:6,666 adults aged ≥50 years from The Irish Longitudinal study on Ageing. METHODS:partic...

journal_title：Age and ageing

authors： Richardson K,Bennett K,Kenny RA

更新日期：2015-01-01 00:00:00

abstract：PRESENTATION:a previously fit 80-year-old woman presented with a 2-week history of spontaneous and extensive bruising affecting all four limbs. The severity was such that she required a transfusion of 8 units of blood. RESULTS OF INVESTIGATIONS:a markedly prolonged activated partial thromboplastin time which was only ...

journal_title：Age and ageing

authors： Kelly J,Gattens M,Geraghty R

更新日期：2000-05-01 00:00:00

abstract：:This paper describes how a sample of elderly people were identified from the electoral register using an initial postal screen, and reports a technique that was used to increase the response to the screen. ...

journal_title：Age and ageing

authors： Cartwright A,Smith C

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:To compare cognitive performance in participants with and without syncope and unexplained falls in a large population representative sample aged 50 years or older. METHODS:Participants of the Irish longitudinal study on ageing (TILDA) were studied. Participants with a history of syncope and/or unexplained fa...

journal_title：Age and ageing

authors： Frewen J,King-Kallimanis B,Boyle G,Kenny RA

更新日期：2015-03-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) isolated from patients with Alzheimer's disease to produce interleukin-1 and -2 (IL-1, IL-2) was compared to that of cells from age-matched controls and young healthy subjects. There was no difference in the production of both interleukins between patients and ...

journal_title：Age and ageing

authors： Bessler H,Sirota P,Hart J,Djaldetti M

更新日期：1989-01-01 00:00:00

abstract：:Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons c...

journal_title：Age and ageing

authors： Kendall MJ

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:epidemiological studies of Alzheimer's disease and aluminium intake have focused on aluminium in drinking water. There have been no studies investigating the relation between the disease and the consumption of foods containing large amounts of aluminium additives. OBJECTIVES:to conduct a pilot study to dete...

journal_title：Age and ageing

authors： Rogers MA,Simon DG

更新日期：1999-03-01 00:00:00

abstract：:A straight abdominal radiograph can be used in the elderly to indicate a loaded colon. Two groups of patients were identified using radiology, one with faeces-filled caeca and the other with gas-filled caeca. Gastro-intestinal transit time measurements and breath methane analysis, an indicator of colonic bacterial act...

journal_title：Age and ageing

authors： McKay LF,Smith RG,Eastwood MA,Walsh SD,Cruikshank JG

更新日期：1983-05-01 00:00:00

abstract：OBJECTIVE:to ascertain the value of employing a specialist clinician's contribution to the assessment of older people prior to care home entry. DESIGN:randomised controlled trial. METHOD:256 older people at risk of care home entry were randomly allocated to either a control group, who received the usual care manageme...

journal_title：Age and ageing

authors： Challis D,Clarkson P,Williamson J,Hughes J,Venables D,Burns A,Weinberg A

更新日期：2004-01-01 00:00:00

abstract：:A 3-year prospective, controlled study of sports injuries in elderly athletes (over 60 years of age) treated at an outpatient sports clinic was carried out in order to determine the number, profile, and specific features of these injuries compared with those of young athletes (between 21 and 25 years). During the stud...

journal_title：Age and ageing

authors： Kannus P,Niittymäki S,Järvinen M,Lehto M

更新日期：1989-07-01 00:00:00

abstract：:In a survey of all 2069 in-patients at 14 geriatric centres, 249 patients were found to have received drugs for the treatment of parkinsonism. There was a wide variation in point prevalence which varied from 4.6% to 22.6% between centres. Levodopa, usually in combination with a decarboxylase inhibitor, was the most fr...

journal_title：Age and ageing

authors： White NJ,Barnes TR

更新日期：1981-05-01 00:00:00