Abstract:
:At concentrations of up to 300 mug/ml both d-threo- and l-threo-chloramphenicol act as energy transfer inhibitors in spinach chloroplasts, in that they inhibit both phosphorylation and phosphorylating electron transport, without affecting the nonphosphorylating electron transport which occurs either in the absence of a phosphate acceptor or in the presence of the uncoupler ammonium chloride. At higher concentrations, there appears to be an additional site of chloramphenicol inhibition of electron transport. If d-threo-chloramphenicol is to be used as a protein synthesis inhibitor in intact chloroplasts or tissues, control experiments with another chloramphenicol isomer seem to be necessary.
journal_name
Plant Physioljournal_title
Plant physiologyauthors
Wara-Aswapati O,Bradbeer JWdoi
10.1104/pp.53.5.691subject
Has Abstractpub_date
1974-05-01 00:00:00pages
691-3issue
5eissn
0032-0889issn
1532-2548journal_volume
53pub_type
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