Daily and circadian variations in serum free testosterone levels are not clinically significant.

Abstract:

:Serum free testosterone levels were measured daily during an ovulatory, endocrinologically normal cycle in five women and at 6-hour intervals on six consecutive days near midcycle in four of these women. During ovulatory cycles, serum free and total testosterone, unlike the gonadotropins, estradiol, and progesterone, did not fluctuate in a cyclic pattern. The 6-hour assays demonstrated close parallelism of free and total testosterone levels and no circadian pattern similar to the diurnal variation seen in serum cortisol values. During both study intervals, the serum free testosterone levels rarely exceeded the upper limit of the normal range defined for our laboratory. Thus, serum free testosterone values measured in blood samples obtained at any day are equally reliable for clinical use.

journal_name

Am J Obstet Gynecol

authors

Strickler RC,Wiest WG,Borth R,Woolever CA

doi

10.1016/0002-9378(81)90281-7

subject

Has Abstract

pub_date

1981-06-01 00:00:00

pages

317-21

issue

3

eissn

0002-9378

issn

1097-6868

pii

0002-9378(81)90281-7

journal_volume

140

pub_type

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    pub_type: 杂志文章

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