Low frequency amplitude modulated microwave fields change calcium efflux rates from synaptosomes.

Abstract:

:Calcium (45Ca2+) efflux from preloaded synaptosomes was studied with a continuous perfusion technique and the rate constants of a two-phase efflux process calculated. When 16-Hz sinusoidally amplitude modulated 450-MHz microwave field (maximal incident intensity 0.5 mW/cm2, modulation depth 75%) was applied during the second phase, the rate constant increased by 38%. Unmodulated or 60-Hz modulated signals were not effective. This microwave field-induced change can be distinguished from CaCl2-stimulated 45Ca2+ efflux which is most probably derived intracellularly. These data suggest that the microwave-field induced change in calcium efflux probably did not involve intracellular calcium. Also, this change in the dynamic property of synaptosomes did not require gross anatomically intact tissue as a substrate for field-tissue interaction.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Lin-Liu S,Adey WR

doi

10.1002/bem.2250030303

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

309-22

issue

3

eissn

0197-8462

issn

1521-186X

journal_volume

3

pub_type

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