Efficacy and safety of butterbur herbal extract Ze 339 in seasonal allergic rhinitis: postmarketing surveillance study.

abstract：INTRODUCTION:This trial was conducted to assess the long-term safety, efficacy, and benefit of early add-on of linagliptin to insulin in patients with type 2 diabetes mellitus (T2DM). METHODS:This trial enrolled 246 subjects. The subjects were randomized to the linagliptin group or the control group and were observed ...

journal_title：Advances in therapy

authors： Katsuno T,Shiraiwa T,Iwasaki S,Park H,Watanabe N,Kaneko S,Terasaki J,Hanafusa T,Imagawa A,Shimomura I,Ikegami H,Koyama H,Namba M,Miyagawa JI,TRUST2 study group.

更新日期：2021-01-28 00:00:00

abstract：:Eupatorium laevigatum Lam. is a plant common to the central region of Brazil, where it is a widely used remedy for lesions such as buccal aphthae. These painful inflammatory ulcers affect 50% of the general population. For the first part of this two-part study, a phytotherapeutic preparation from E. laevigatum extract...

journal_title：Advances in therapy

authors： Paulo Filho W,Ribeiro JE,Pinto DS

更新日期：2000-11-01 00:00:00

abstract：:Traveling through several time zones results in a constellation of symptoms known as jet lag. These include reduced alertness, daytime fatigue, loss of appetite, reduced cognitive skills, and disruption of the sleep/wake cycle. In susceptible air travel passengers, jet lag may exacerbate affective illness and result i...

journal_title：Advances in therapy

authors： Srinivasan V,Singh J,Pandi-Perumal SR,Brown GM,Spence DW,Cardinali DP

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:In FRESCO (Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients) trial, fruquintinib demonstrated a statistically significant and clinically meaningful overall survival benefit in Chinese patients with metastatic colorectal cancer (mCRC). However, its safety profile, including adverse eve...

journal_title：Advances in therapy

authors： Li J,Guo W,Bai Y,Deng Y,Yang L,Chen Z,Zhong H,Xu R,Pan H,Shu Y,Yuan Y,Zhou J,Xu N,Liu T,Ma D,Wu C,Cheng Y,Xu J,Chen D,Li W,Sun S,Yu Z,Cao P,Shen L,Chen H,Wang S,Wang H,Fan S,Guo X,Wang N,Han R

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:New biosimilars of monoclonal antibodies are anticipated to bring significant cost savings and increase access to treatment. The rituximab biosimilar CT-P10 has recently been approved in Europe in all indications held by reference rituximab (RTX), including rheumatoid arthritis, non-Hodgkin's lymphoma, and...

journal_title：Advances in therapy

authors： Gulácsi L,Brodszky V,Baji P,Rencz F,Péntek M

更新日期：2017-05-01 00:00:00

abstract：:Cardiovascular diseases (CVDs) are the leading cause of premature deaths globally and in Ukraine. Dyslipidemia is a recognized risk factor for the development of CVD. Therefore, early detection and appropriate management of dyslipidemia are essential for the primary prevention of CVDs. However, currently, there is a l...

journal_title：Advances in therapy

authors： Dolzhenko MM,Barnett OY,Grassos C,Dragomiretska NV,Goloborodko BI,Ilashchuk TO,Zuiev KO,Karpenko OV,Kolesnikova OV,Kolesnyk TV,Talaieva TV,Vakaliuk IP,Tiabut TD,Mesnikova IL,Zinych OV

更新日期：2020-11-01 00:00:00

abstract：:Knee osteoarthritis (KOA) is the most common musculoskeletal disorder, especially in middle up to old age. KOA also results in many complications like changes in gait. Nowadays, changes in lifestyle and the reduced physical activity make people more vulnerable to KOA. Therefore, considering the increasing prevalence o...

journal_title：Advances in therapy

authors： Ganjeh S,Rezaeian ZS,Mostamand J

更新日期：2020-08-01 00:00:00

abstract：:The tolerability of brimonidine tartrate 0.15%--referred to as bromonidine-Purite 0.15% in this study--was compared with brimonidine tartrate 0.2% in irritated eyes of healthy volunteers as well as patients with glaucoma or ocular hypertension (N=20) in a 2-week, single-center, randomized, double-masked, crossover stu...

journal_title：Advances in therapy

authors： Mundorf T,Wilcox KA,Ousler GW 3rd,Welch D,Abelson MB

更新日期：2003-11-01 00:00:00

abstract：INTRODUCTION:Comparisons between brand and biosimilar basal insulin in hospitalized patients are lacking. We aimed to compare the efficacy and safety of brand insulin glargine vs. biosimilar insulin glargine in non-critical hospitalized patients with type 2 diabetes mellitus (T2DM). METHODS:This retrospective study wa...

journal_title：Advances in therapy

authors： Hu X,Zhang L,Dong C,Dong Y,Jiang J,Gao W

更新日期：2019-05-01 00:00:00

abstract：:This multicenter, double-masked, randomized, parallel-group study compared the efficacy and safety of ketorolac tromethamine 0.5% ophthalmic solution with levocabastine 0.05% and ketorolac tromethamine vehicle in patients with seasonal allergic conjunctivitis. One drop of ketorolac, levocabastine, or vehicle was insti...

journal_title：Advances in therapy

authors： Donshik PC,Pearlman D,Pinnas J,Raizman MB,Tauber J,Tinkelman D,Walters TR

更新日期：2000-03-01 00:00:00

abstract：INTRODUCTION:The aim of this analysis was to characterize the safety and tolerability of empagliflozin in patients with type 2 diabetes mellitus (T2DM) who were randomized to empagliflozin (10/25 mg) or placebo in clinical trials. METHODS:Pooled data from 20 trials were analyzed for patients with T2DM treated with emp...

journal_title：Advances in therapy

authors： Kinduryte Schorling O,Clark D,Zwiener I,Kaspers S,Lee J,Iliev H

更新日期：2020-08-01 00:00:00

abstract：:Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to...

journal_title：Advances in therapy

authors： Coca-Pelaz A,Barnes L,Rinaldo A,Cardesa A,Shah JP,Rodrigo JP,Suárez C,Eloy JA,Bishop JA,Devaney KO,Thompson LD,Wenig BM,Strojan P,Hamoir M,Bradley PJ,Gnepp DR,Silver CE,Slootweg PJ,Triantafyllou A,Vander Poorten V,

更新日期：2016-04-01 00:00:00

abstract：:This study was conducted to assess clinical and cost outcomes associated with the use of daptomycin. This objective was addressed through a consecutive patient chart review of the first 50 inpatients treated with daptomycin. Type of infection, identity of isolated pathogens, prior therapy, duration of therapy, length ...

journal_title：Advances in therapy

authors： Fossaceca C

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:This pooled analysis of data from three phase 3 studies in patients with chronic osteoarthritis knee or low back pain evaluated the efficacy and tolerability of tapentadol prolonged release (PR; 100-250 mg twice daily) compared with placebo and oxycodone hydrochloride (HCl) controlled release (CR; 20-50 mg...

journal_title：Advances in therapy

authors： Lange B,Kuperwasser B,Okamoto A,Steup A,Häufel T,Ashworth J,Etropolski M

更新日期：2010-06-01 00:00:00

abstract：:Combination therapies are a widely accepted approach to type 2 diabetes treatment, considering that monotherapies fail to provide adequate glycemic control in the majority of cases. The combination of oral antidiabetic agents into a single tablet would significantly simplify the therapeutic regimen and maximize patien...

journal_title：Advances in therapy

authors： Koliaki C,Doupis J

更新日期：2012-12-01 00:00:00

abstract：:Ambulatory monitoring was used to evaluate the antihypertensive efficacy and effect on circadian rhythms of blood pressure and heart rate of a single dose and long-term administration of ramipril in 20 patients with mild to moderate essential hypertension. Patients initially were randomized to receive either placebo o...

journal_title：Advances in therapy

authors： Cavazzini D,Amadei G,Manfredini R,Musacci G,Mele D,Longhini C

更新日期：1995-01-01 00:00:00

abstract：:In an open, uncontrolled study, 105 patients with locomotor system symptoms were treated twice daily with an ointment containing a Symphytum active substance complex. A clear therapeutic effect was noted on chronic and subacute symptoms that were accompanied mainly by functional disturbances and pain in the musculatur...

journal_title：Advances in therapy

authors： Kucera M,Kálal J,Polesná Z

更新日期：2000-07-01 00:00:00

abstract：INTRODUCTION:Ample evidence suggested a role of sigma-1 receptor in affective disorders since the interaction of numerous antidepressants with sigma receptors was discovered. A recent study on Japanese subjects found a genetic variant within the encoding gene SIGMAR1 (rs1800866A>C) associated with major depressive diso...

journal_title：Advances in therapy

authors： Mandelli L,Wang SM,Han C,Lee SJ,Patkar AA,Masand PS,Pae CU,Serretti A

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:Benefit and risk of anticoagulation in cirrhotic patients with portal vein thrombosis (PVT) remain controversial, especially in those with asymptomatic PVT and in non-liver transplant candidates. Furthermore, the predictors of portal vein recanalization and bleeding events after anticoagulation are critica...

journal_title：Advances in therapy

authors： Wang L,Guo X,Xu X,De Stefano V,Plessier A,Noronha Ferreira C,Qi X

更新日期：2020-11-05 00:00:00

abstract：:Many doubts surround the numerous forms of nonsurgical treatment of nonresectable hepatocellular carcinoma (HCC). Our study aimed to reach reliable conclusions on the actual efficacy of these treatments. We examined 85 studies involving a total of 6746 patients: 6113 were treated; the remaining 633 were not. We applie...

journal_title：Advances in therapy

authors： Malaguarnera M,Trovato G,Restuccia S,Giugno I,Franzé CM,Receputo G,Siciliano R,Motta M,Trovato BA

更新日期：1994-11-01 00:00:00

abstract：INTRODUCTION:Vitamin E is one of the most promising agents for nonalcoholic steatohepatitis (NASH) treatment, and its drug responsiveness may be closely associated with haptoglobin (Hp) genotype. However, its efficacy and safety remain unknown in China. This clinical trial of vitamin E versus placebo for the treatment ...

journal_title：Advances in therapy

authors： Zang S,Chen J,Song Y,Bai L,Chen J,Chi X,He F,Sheng H,Wang J,Xie S,Xie W,Yang Y,Zhang J,Zheng M,Zou Z,Wang B,Shi J,Chinese NAFLD Clinical Research Network (CNAFLD CRN).

更新日期：2018-02-01 00:00:00

abstract：:Propolis is a natural product produced by bees that was discovered through the study of traditional cures and knowledge of indigenous people throughout the world. It is rich in vitamins A, B, C, and E, and in amino acids, copper, iron, manganese, and zinc. The investigators studied the duration-dependent hepatoprotect...

journal_title：Advances in therapy

authors： Bhadauria M,Nirala SK,Shukla S

更新日期：2007-09-01 00:00:00

abstract：:Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. Here we carry out the first systematic review of literature ...

journal_title：Advances in therapy

authors： Olson A,Hartmann N,Patnaik P,Wallace L,Schlenker-Herceg R,Nasser M,Richeldi L,Hoffmann-Vold AM,Cottin V

更新日期：2020-12-14 00:00:00

abstract：INTRODUCTION:Ivabradine has opened up new possibilities for treating stable angina and chronic heart failure by lowering heart rate. Ivabradine lowers heart rate by selectively inhibiting the I f current in the sinoatrial node. This study aimed to determine whether the decrease in heart rate achieved with ivabradine wa...

journal_title：Advances in therapy

authors： Jedlickova L,Merkovska L,Jackova L,Janicko M,Fedacko J,Novakova B,Chmelarova A,Majernik J,Pella D

更新日期：2015-10-01 00:00:00

abstract：:Hyperthyroidism is associated with increased bone turnover. Besides the hormones of calcium metabolism, locally produced factors are important in maintaining normal bone metabolism. Interleukin-6 (IL-6), in particular, has a major influence on bone turnover. In this study, serum IL-6 and tumor necrosis factor-alpha (T...

journal_title：Advances in therapy

authors： Sekeroglu MR,Altun ZB,Algün E,Dülger H,Noyan T,Balaharoglu R,Oztürk M

更新日期：2006-05-01 00:00:00

abstract：INTRODUCTION:The purpose of the study was to conduct a cost-effectiveness analysis and budget impact analysis comparing lopinavir with ritonavir (LPV/r) and atazanavir plus ritonavir (ATV+RTV) for antiretroviral-naïve patients with a baseline CD4+ T-cell distribution and total cholesterol (TC) profile as reported in th...

journal_title：Advances in therapy

authors： Simpson KN,Rajagopalan R,Dietz B

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:Extraintestinal manifestations (EIMs) in patients with Crohn's disease (CD) are common and associated with additional morbidity. This study aimed to evaluate the effect of adalimumab therapy on EIM resolution and identify potential predictors of EIM resolution in adult and pediatric patients with moderate ...

journal_title：Advances in therapy

authors： Louis EJ,Reinisch W,Schwartz DA,Löfberg R,Robinson AM,Berg S,Wang AW,Maa JF,Huang B,Pappalardo B

更新日期：2018-04-01 00:00:00

abstract：:Brucellosis remains an important public health problem in Turkey, just as it is in other regions of the world. This study was conducted to determine the types and rates of cutaneous lesions that occur in patients with brucellosis. Brucellosis was diagnosed by standard tube agglutination testing for Brucella antibodies...

journal_title：Advances in therapy

authors： Akcali C,Savas L,Baba M,Turunc T,Seckin D

更新日期：2007-07-01 00:00:00

abstract：INTRODUCTION:This study aimed to demonstrate the clinical utility of non-invasive multigene Cxbladder urine tests in reducing the overall number of diagnostic tests and invasive procedures used in the clinical evaluation of patients presenting with microhematuria, a key symptom of urothelial carcinoma (UC). There is a ...

journal_title：Advances in therapy

authors： Darling D,Luxmanan C,O'Sullivan P,Lough T,Suttie J

更新日期：2017-05-01 00:00:00

abstract：:In this double-blind, randomized, placebo-controlled, prospective study, the clinical efficacy and tolerability of oral Hypericum extract STW 3-VI (Laif) 900 mg once daily was compared with that of placebo. A total of 140 outpatients (94 women; 46 men) with moderate depressive disorders and a 17-item Hamilton Depressi...

journal_title：Advances in therapy

authors： Uebelhack R,Gruenwald J,Graubaum HJ,Busch R

更新日期：2004-07-01 00:00:00