Abstract:
:The pattern dystrophies are a group of hereditary macular dystrophies characterized by lesions of the retinal pigment epithelium (RPE) arranged in various patterns of dots, lines, and branched figures. This report of two pedigrees expands the clinical spectrum. The onset is usually in the second and third decade, there is great variation in fundus appearance, vision may be severely affected, the EOG is not always abnormal, and the fundus lesions change with time. The lesions resemble those of Best's vitelliform degeneration and fundus flavimaculatus, and, possibly, also represent abnormal lipofuscin accumulation within degenerating retinal pigment epithelial cells.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Watzke RC,Folk JC,Lang RMdoi
10.1016/s0161-6420(82)34632-1subject
Has Abstractpub_date
1982-12-01 00:00:00pages
1400-6issue
12eissn
0161-6420issn
1549-4713pii
S0161-6420(82)34632-1journal_volume
89pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract:OBJECTIVE:To assess the structure of central optic disc pits (ODPs) using enhanced-depth imaging optical coherence tomography (EDI OCT) and to ascertain their clinical significance. DESIGN:Prospective, cross-sectional study. PARTICIPANTS:Patients with an ophthalmoscopically visible central ODP in either eye, irrespec...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.12.034
更新日期:2013-07-01 00:00:00
abstract::A low cost microcomputer was used to: (1) word process and edit this manuscript, (2) create a patient file storage and retrieval system, (3) transcribe and store information from video display such as wide-angle fundus photographs and fluorescein angiograms, (4) plot data points in graphic display mode, (5) solve comp...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34867-8
更新日期:1982-01-01 00:00:00
abstract:PURPOSE:To evaluate prospectively the efficacy of a single sub-Tenon's capsule injection of triamcinolone acetonide (TA) against panretinal photocoagulation (PRP)-induced macular thickening and visual disturbance in patients with severe diabetic retinopathy and good vision. DESIGN:Prospective, comparative, interventio...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.10.035
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:To identify factors that influence the outcome of patients with severe infectious corneal ulcers. METHOD:A retrospective review was performed of the hospital records of all such patients admitted to the Doheny Eye Hospital during a 30 month period. Outcome variables examined were change in visual acuity, durat...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(95)30771-3
更新日期:1995-12-01 00:00:00
abstract::Between April 1986 and April 1989, the authors conducted a prospective study of the use of open-loop anterior chamber intraocular lenses (AC IOLs) in patients undergoing penetrating keratoplasty for pseudophakic bullous keratopathy or monocular aphakic bullous keratopathy. All patients underwent the same operation--a ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(90)32513-7
更新日期:1990-06-01 00:00:00
abstract:PURPOSE:To evaluate the clinical features, treatment, and prognosis of patients with uveal metastasis from lung cancer. DESIGN:Retrospective chart review. PARTICIPANTS:There were 194 patients with a diagnosis of uveal metastasis from lung cancer. INTERVENTION:Radiotherapy, chemotherapy, enucleation, or observation. ...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2013.07.014
更新日期:2014-01-01 00:00:00
abstract::The authors studied 50 eyes with atrophic (dry) macular degeneration (geographic atrophy of age-related macular degeneration [GAMD], in 50 consecutive patients for 2 to 6 years (average, 3.4 years). There were 35 women and 15 men ranging in age from 60 to 89 years (average, 73 years). The areas of atrophy tended to fo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32694-7
更新日期:1989-10-01 00:00:00
abstract:PURPOSE:To compare the efficacy, safety, and risk factors for failure of standalone ab interno gelatin microstent implantation with mitomycin C (MMC) versus trabeculectomy with MMC. DESIGN:International, multicenter, retrospective interventional cohort study. PARTICIPANTS:Three hundred fifty-four eyes of 293 patients...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2017.05.004
更新日期:2017-11-01 00:00:00
abstract::One hundred twelve patients with vitiligo were examined for ocular abnormalities. Discrete areas of depigmentation with associated pigment hyperplasia clinically appearing to involve the choroid and retinal pigment epithelium were observed in 44 patients, and active uveitis was seen in nine patients. The changes obser...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(79)35413-6
更新日期:1979-06-01 00:00:00
abstract::A new procedure for neovascular glaucoma that has reduced intraocular pressure (IOP) significantly and has caused relatively few postoperative complications is introduced. Aqueous is shunted to the reservoir of an encircling no. 20 silicone band from which fluid is postulated to diffuse into the orbit. The anterior ch...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34671-0
更新日期:1982-10-01 00:00:00
abstract:OBJECTIVE:The purpose of the study is to determine safety and efficacy outcomes of excimer laser photorefractive keratectomy (PRK) for the treatment of mild-to-moderate myopia. DESIGN:A prospective, multicenter, phase III clinical trial. PARTICIPANTS:A total of 701 eyes of 701 patients were entered in the study; 612 ...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/s0161-6420(97)30073-6
更新日期:1997-10-01 00:00:00
abstract::A 34-year-old white man with skin manifestations of the epidermal nevus syndrome was found to have anesthetic corneas, dry eyes, and localized opaque nodular elevations of both corneas. Similar corneal lesions, unassociated with corneal anesthesia, were found in four family members. Histology of corneal biopsies from ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34320-2
更新日期:1984-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and efficacy of transnasal orbital decompression for severe Graves' ophthalmopathy. DESIGN:Retrospective noncomparative case series with extended clinical follow-up. PARTICIPANTS:Seventy-eight consecutive subjects who were operated on for compressive optic neuropathy with loss of visu...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00533-9
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:Subconjunctival hemorrhage (SCH) is a relatively common disease, but there have been no reports concerning the relationship between SCH and conjunctivochalasis (CCh). We compared the grade of CCh between patients with SCH and control patients. DESIGN:Prospective, nonrandomized study. PARTICIPANTS:A total of...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.03.021
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To assess the relative risks (RR) of microbial keratitis (MK) for contemporary contact lens (CL) types and wearing schedules. DESIGN:A 2-year prospective case-control study begun in December 2003. PARTICIPANTS:Cases were 367 CL wearers attending Moorfields Eye Hospital with proven or presumed MK. Controls w...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.05.003
更新日期:2008-10-01 00:00:00
abstract:PURPOSE:To develop a universal gene therapy to overcome the genetic heterogeneity in retinitis pigmentosa (RP) resulting from mutations in rhodopsin (RHO). DESIGN:Experimental study for a combination gene therapy that uses both gene ablation and gene replacement. PARTICIPANTS:This study included 2 kinds of human RHO ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2018.04.001
更新日期:2018-09-01 00:00:00
abstract::Transient changes in the corneal endothelium were the earliest detectable response to low atmospheric oxygen in experimental animals. Similar changes have been reported after hard and soft contact lens wear. We describe widespread transient cell changes by wide-field specular microscopy in the normal corneal endotheli...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34169-0
更新日期:1984-10-01 00:00:00
abstract::Acyclovir, an oral antiviral agent that inhibits viral DNA replication, was used to treat 27 patients (16 males, 11 females) (mean age, 50 years) with vision-threatening herpes simplex virus (HSV) infections. Twenty patients had active stromal keratitis or keratouveitis, four had controlled nonnecrotizing stromal kera...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33156-8
更新日期:1988-04-01 00:00:00
abstract:PURPOSE:The existence of genetic variations in a number of cytokines has been considered to influence susceptibility or relate to disease severity in various autoimmune diseases. Among these, single-nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha (TNF-alpha) promoter at nucleotides -308 and -238 are ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.01.004
更新日期:2006-04-01 00:00:00
abstract:PURPOSE:To develop a standardized clinical grading system for the management of patients with vernal keratoconjunctivitis (VKC) and to identify the risk factors associated with a worsened outcome of the disease, including decrease of visual acuity and ocular complications development. DESIGN:Retrospective cohort study...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.11.043
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:To evaluate the short-term and long-term variability of intraocular pressure (IOP) in eyes with primary open-angle glaucoma. DESIGN:Prospective study. PARTICIPANTS:Twenty-two patients previously implanted with a sulcus-based IOP sensor (EyeMate, Implandata GmbH, Germany). METHODS:Twenty-two patients previous...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2020.07.016
更新日期:2021-02-01 00:00:00
abstract::Twenty-three patients who underwent penetrating keratoplasty were evaluated preoperatively for potential retinal acuity utilizing the Randwal Laser Interferometer and the Mentor Potential Acuity Meter. When compared with Snellen visual acuity during the early postoperative period (1-6 months), both instruments were us...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34172-0
更新日期:1984-10-01 00:00:00
abstract::The authors studied 80 eyes of patients with choroidal neovascular membranes (CNVMs) associated with age-related macular degeneration between 1982 and 1988. In each case, fluorescein angiography was done on two occasions separated by an interval of 2 days to 11 weeks (average, 13 days) without intervening photocoagula...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32741-2
更新日期:1989-09-01 00:00:00
abstract::An elderly, Spanish-speaking patient, who was a poor historian, presented with a hemorrhagic corneal condition that was mistakenly diagnosed as a spontaneous expulsive choroidal hemorrhage leading to enucleation of the globe. The enucleation specimen revealed pathologically a diffuse hemorrhagic pannus without corneal...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34964-1
更新日期:1981-07-01 00:00:00
abstract:PURPOSE:The authors analyzed all the complications associates with the first 100 hydroxyapatite orbital implants performed by one surgeon, and compare scleral wrapping versus Dexon mesh (polyglycolic acid, Davis & Geck, Manati, Puerto Rico) wrapping in light of these complications. BACKGROUND:Prior studies have not in...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0161-6420(97)30316-9
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:To analyze the association of the polymorphisms in 8-oxoguanine glycosylase-1 (OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) genes in the base excision repair pathway and xeroderma pigmentosum complementation group D (XPD) in the nucleotide excision repair pathway with the risk...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.11.004
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To investigate refractive error in eyes with nonarteritic anterior ischemic optic neuropathy (NA-AION) and its relationship to cup/disc (C/D) ratio. DESIGN:Cohort study. PARTICIPANTS:A total of 608 consecutive patients with NA-AION. METHODS:At first visit, all patients had a comprehensive ophthalmic evalua...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.08.007
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:To describe the results from a statewide preschool vision screening program using the MTI PhotoScreener (Medical Technology and Innovations, Inc., Cedar Falls, IA). DESIGN:Cross-sectional study. PARTICIPANTS:A total of 15,059 children aged 6 to 47 months enrolled in childcare and preschool settings throughout...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00298-0
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:To provide a set of surveillance guidelines for children at risk for development of retinoblastoma. DESIGN:Consensus panel. PARTICIPANTS:Expert panel of ophthalmic oncologists, pathologists, and geneticists. METHODS:A group of members of the American Association of Ophthalmic Oncologists and Pathologists (AA...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2017.09.001
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To assess the status of choriocapillaris in eyes with macular atrophy secondary to age-related macular degeneration (AMD) (geographic atrophy [GA]) and Stargardt disease (STGD) using optical coherence tomography angiography (OCTA). DESIGN:Prospective, observational case series. PARTICIPANTS:A total of 14 pati...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2016.05.041
更新日期:2016-09-01 00:00:00