Pattern dystrophy of the retinal pigment epithelium.

Abstract:

:The pattern dystrophies are a group of hereditary macular dystrophies characterized by lesions of the retinal pigment epithelium (RPE) arranged in various patterns of dots, lines, and branched figures. This report of two pedigrees expands the clinical spectrum. The onset is usually in the second and third decade, there is great variation in fundus appearance, vision may be severely affected, the EOG is not always abnormal, and the fundus lesions change with time. The lesions resemble those of Best's vitelliform degeneration and fundus flavimaculatus, and, possibly, also represent abnormal lipofuscin accumulation within degenerating retinal pigment epithelial cells.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Watzke RC,Folk JC,Lang RM

doi

10.1016/s0161-6420(82)34632-1

subject

Has Abstract

pub_date

1982-12-01 00:00:00

pages

1400-6

issue

12

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(82)34632-1

journal_volume

89

pub_type

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