Iron deposits surrounding multiple sclerosis plaques.

Abstract:

:Autopsy samples from cerebral areas of five brains from patients with multiple sclerosis (MS) and from six control brains were stained with Perls acid ferrocyanide to detect nonheme iron present as hemosiderin. Positive iron reactions were observed only in MS sections surrounding demyelinated plaques. Myelinated white matter near the lesion contained numerous iron-laden ovoid bodied and axons that stained positively for iron. Positive reactions were also found within blood vessels of gray matter near the lesion. A possible source of the iron was extravasated blood.

journal_name

Arch Pathol Lab Med

authors

Craelius W,Migdal MW,Luessenhop CP,Sugar A,Mihalakis I

subject

Has Abstract

pub_date

1982-08-01 00:00:00

pages

397-9

issue

8

eissn

0003-9985

issn

1543-2165

journal_volume

106

pub_type

杂志文章
  • The specificity of split renal membranes in hereditary nephritis.

    abstract::This study was undertaken to assess the specificity of split renal basement membranes in hereditary nephritis (HN). Thirteen specimens from eight patients with HN were mixed in a random fashion with specimens from control patients with either idiopathic nephrotic syndrome or various forms of glomerulonephritis and wit...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Kohaut EC,Singer DB,Nevels BK,Hill LL

    更新日期:1976-09-01 00:00:00

  • Ovarian neuroendocrine carcinoma associated with a mucinous neoplasm.

    abstract::We describe a rare case of a neuroendocrine carcinoma of the ovary in a 22-year-old woman who presented with abdominal pain and a pelvic mass. Exploratory laparotomy revealed a right ovarian tumor weighing 2100 g. A right salpingo-oophorectomy and an appendectomy were performed. There was no evidence intraoperatively ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Khurana KK,Tornos C,Silva EG

    更新日期:1994-10-01 00:00:00

  • Vascular transformation of lymph node sinuses. A process displaying a spectrum of histologic features.

    abstract::Nonneoplastic vascular lesions in lymph nodes have been infrequently reported. These lesions are believed to be rare and display histologic features ranging from minimal changes associated with vasodilation to vascular proliferative lesions resembling Kaposi's sarcoma. The spectrum of histologic features observed in t...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Ostrowski ML,Siddiqui T,Barnes RE,Howton MJ

    更新日期:1990-07-01 00:00:00

  • Meningioma with sarcomatous change and hepatic metastasis.

    abstract::A 72-year-old patient had a meningotheliomatous meningioma that invaded through the skull and into temporalis muscle. One year following craniotomy for removal of the neoplasm, he developed headaches, diplopia, and proptosis of the left eye. Biopsy of the orbital contents revealed a malignant supporting tissue neoplas...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Repola D,Weatherbee L

    更新日期:1976-12-01 00:00:00

  • The impact of gene expression microarrays in the evaluation of lung carcinoma subtypes and DNA copy number.

    abstract:CONTEXT:The development of targeted therapies creates a need to accurately classify tumors. Among the more pressing needs are the identification of the complete catalog of genes that are altered in cancer and the accurate discrimination of tumors based on their genetic background. OBJECTIVES:To discuss the use of gene...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/1543-2165(2008)132[1562:TIOGEM]2.0.CO;2

    authors: Sanchez-Cespedes M

    更新日期:2008-10-01 00:00:00

  • Selective myocardial cell necrosis in nonhuman primates.

    abstract::A retrospective study was performed to describe the histologic stages of selective myocardial cell necrosis (SMCN) in nonhuman primates, and to compare the incidence of SMCN in two groups of nonhuman primates. Myocardial tissues taken at the time of autopsy from 50 primates at an experimental center were compared with...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Cowan MJ,Giddens WE Jr,Reichenbach DD

    更新日期:1983-01-01 00:00:00

  • Phenytoin inhibition: failure to inhibit periosteal responses to lathyrogen.

    abstract::beta-Aminopropionitrile (BAPN) administered to rats has caused exostosis formation at sites of muscle attachment and also caused delay in the healing of soft tissue wounds and of bone fractures. Since phenytoin sodium has an opposite effect on wound healing, bone fractures, and the tensile strength of connective tissu...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Fallon MD,Yeager VL,Taylor JL

    更新日期:1977-02-01 00:00:00

  • Primary rhabdomyosarcoma of the ileum in an adult.

    abstract::We report a case of primary rhabdomyosarcoma of the ileum occurring in a 45-year-old man. The rhabdomyoblastic nature was immunohistochemically confirmed by positivity with anti-myoglobin and anti-striated actin antisera. We discuss the differential diagnosis with similar tumors. To our knowledge, ileal rhabdomyosarco...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Damiani S,Nappi O,Eusebi V

    更新日期:1991-03-01 00:00:00

  • Pulmonary phospholipid accumulation distal to an obstructed bronchus. A morphologic study.

    abstract::Alveolar proteinosis (AP) and postobstructive or endogenous lipid pneumonia (ELP) are two distinct morphologic types of phospholipid accumulation in the lung. In ELP, ultrastructurally amorphous fat accumulates in the cytoplasm of alveolar macrophages. In AP, lamellar surfactant bodies with an electron microscopic com...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Verbeken EK,Demedts M,Vanwing J,Deneffe G,Lauweryns JM

    更新日期:1989-08-01 00:00:00

  • Multiple factors contribute to positive results for hepatitis A virus immunoglobulin M antibody.

    abstract:CONTEXT:In the United States, a successful vaccination program for hepatitis A virus (HAV) infection has decreased both its incidence and the true positive rate for diagnostic immunoglobulin M (IgM) antibody to HAV in acute hepatitis. OBJECTIVE:To survey positive results of HAV IgM tests and determine the effect of ch...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2011-0693-OA

    authors: Alatoom A,Ansari MQ,Cuthbert J

    更新日期:2013-01-01 00:00:00

  • Atypical endocrine tumors of the lung.

    abstract::Seven malignant peripheral lung tumors that were diagnosed using light microscopy as large-cell carcinomas or as epidermoid or adenocarcinomas were studied by light and electron microscopic histochemistry. All tumors contained numerous dense-core granules. The cells were joined by desmosomes and contained well-develop...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: McDowell EM,Wilson TS,Trump BF

    更新日期:1981-01-01 00:00:00

  • Tubuloreticular inclusions in systemic lupus pneumonitis. Report of a case and review of the literature.

    abstract::Tubuloreticular inclusions have been described with sufficient frequency in certain tissues of patients with systemic lupus erythematosus (SLE) to make the finding of such inclusions helpful in making a diagnosis of this disorder. The finding of such inclusions in lung biopsy specimens, however, has been distinctly ra...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Lyon MG,Bewtra C,Kenik JG,Hurley JA

    更新日期:1984-07-01 00:00:00

  • Multiparameter flow cytometry in the diagnosis and management of acute leukemia.

    abstract:CONTEXT:Timely and accurate diagnosis of hematologic malignancies is crucial to appropriate clinical management. Acute leukemias are a diverse group of malignancies with a range of clinical presentations, prognoses, and preferred treatment protocols. Historical classification systems relied predominantly on morphologic...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/2010-0387-RAR.1

    authors: Peters JM,Ansari MQ

    更新日期:2011-01-01 00:00:00

  • Measurement of mercury levels in concentrated over-the-counter fish oil preparations: is fish oil healthier than fish?

    abstract:CONTEXT:Fish consumption has been associated with a decreased risk of coronary artery disease. Recent studies have illustrated that the high mercury content in cold-water fish may negate the cardiovascular benefits of fish meals. Fish oils have similar antiatherogenic properties to fish, and similar studies should be p...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2003)127<1603:MOMLIC>2.0.CO;2

    authors: Foran SE,Flood JG,Lewandrowski KB

    更新日期:2003-12-01 00:00:00

  • Informed evaluation of pathology residency programs.

    abstract:OBJECTIVES:To identify resources and summarize important issues in anatomic and clinical pathology training and to assist the pathology resident candidate in evaluating potential training programs. DATA SOURCES:Published guides for medical residency applicants, recent literature discussing pathology education, and Wor...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2000)124<0853:IEOPRP>2.0.CO;2

    authors: Yorke RF

    更新日期:2000-06-01 00:00:00

  • Expression of melanoma antigens in epithelioid gastrointestinal stromal tumors: a potential diagnostic pitfall.

    abstract:CONTEXT:Most gastric gastrointestinal stromal tumors (GISTs) express CD117/c-kit, as do a subset of metastatic melanomas, leading to a diagnostic dilemma in some cases. OBJECTIVE:To further differentiate GISTs from melanoma, we investigated expression of melanoma markers in GISTs using a well-characterized set of gast...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2008)132[1302:EOMAIE]2.0.CO;2

    authors: Guler ML,Daniels JA,Abraham SC,Montgomery EA

    更新日期:2008-08-01 00:00:00

  • Skeletal myxoid chondrosarcoma with microtubular aggregates within rough endoplasmic reticulum.

    abstract::A skeletal myxoid chondrosarcoma of the femur was examined by light and electron microscopy. Light microscopic features were characteristic for myxoid chondrosarcoma or "chordoid sarcoma." Electron microscopy disclosed crystalline arrays of microtubules within dilated rough endoplasmic reticulum, a feature previously ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Wolford JF,Bedetti CD

    更新日期:1988-01-01 00:00:00

  • Cytogenetic studies of 24 renal epithelial tumors with von Hippel-Lindau and fragile histidine triad protein expression correlation.

    abstract:CONTEXT:Deletion of the short arm of chromosome 3 (3p deletion) is a cytogenetic abnormality generally associated with clear cell renal cell carcinoma, the most aggressive form of renal epithelial tumor. OBJECTIVE:To cytogenetically characterize 24 renal tumors in order to check the incidence and the type of 3p deleti...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2008)132[965:CSORET]2.0.CO;2

    authors: Gayrard N,Cacheux V,Iborra F,Mourad G,Argilés A

    更新日期:2008-06-01 00:00:00

  • Primary non-Hodgkin's lymphoma of the heart in two patients with the acquired immunodeficiency syndrome.

    abstract::We report two cases of primary cardiac lymphoma that developed in patients suffering from the acquired immunodeficiency syndrome. Both cases of lymphoma were histologically aggressive as generally observed in patients with the acquired immunodeficiency syndrome. The lymphoma cells in the center of a tumor nodule obtai...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Guarner J,Brynes RK,Chan WC,Birdsong G,Hertzler G

    更新日期:1987-03-01 00:00:00

  • Update on selected salivary gland neoplasms.

    abstract:CONTEXT:Malignancies of the salivary gland are uncommon and account for 0.3% of all malignancies. In addition to their rarity, diagnosing these tumors can be challenging given the histologic overlap among various subtypes, their morphologic heterogeneity, and the recent recognition of new entities. OBJECTIVE:To provid...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165-133.11.1763

    authors: McHugh JB,Visscher DW,Barnes EL

    更新日期:2009-11-01 00:00:00

  • Histogenesis of papillomas of the nose and paranasal sinuses.

    abstract:OBJECTIVE:To determine by review of their histogenesis whether papillomas of the nose and paranasal sinuses are three distinct entities or, as has been favored in the literature, three variations of a single entity. METHODS AND PATIENTS:We examined biopsy sections from 191 patients with sinonasal papillomas. Biopsy se...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Michaels L,Young M

    更新日期:1995-09-01 00:00:00

  • Menkes' syndrome with vascular and adrenergic nerve abnormalities.

    abstract::Using the formaldehyde-induced fluorescence method, we found a peculiar rosary-type swelling of the adrenergic axons in the peripheral nerves, deficiency of the perivascular adrenergic plexuses in the visceral and cerebral arteries, and reduction of noradrenergic fluorescence in the tegmental and hypothalamic regions ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Uno H,Arya S,Laxova R,Gilbert EF

    更新日期:1983-06-01 00:00:00

  • Kaposiform hemangioendothelioma associated with nonimmune fetal hydrops.

    abstract::We describe the case of a 31-week fetus who died in utero with an invasive retroperitoneal kaposiform hemangioendothelioma. This rare vascular neoplasm usually presents as a localized violaceous skin lesion in infants and behaves in a benign fashion; however, kaposiform hemangioendothelioma may present as an invasive ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2004)128<678:KHAWNF>2.0.CO;2

    authors: Martinez AE,Robinson MJ,Alexis JB

    更新日期:2004-06-01 00:00:00

  • Extraneous tissue in surgical pathology: a College of American Pathologists Q-Probes study of 275 laboratories.

    abstract:OBJECTIVE:To develop a multi-institutional reference database of extraneous tissue (contaminants) in surgical pathology. DESIGN:In 1994, participants in the College of American Pathologists Q-Probes quality improvement program performed prospective and retrospective evaluations of extraneous tissue found in surgical p...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Gephardt GN,Zarbo RJ

    更新日期:1996-11-01 00:00:00

  • Uniform Labeling of Blocks and Slides in Surgical Pathology: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center and the National Society for Histotechnology.

    abstract:CONTEXT:The labeling of paraffin blocks and microscopic glass slides in the practice of surgical pathology varies from institution to institution and introduces potential risk of preanalytic error. Currently there are no evidence-based guidelines regarding the uniform labeling of these materials. OBJECTIVE:To develop ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 指南,杂志文章

    doi:10.5858/arpa.2014-0340-SA

    authors: Brown RW,Della Speranza V,Alvarez JO,Eisen RN,Frishberg DP,Rosai J,Santiago J,Tunnicliffe J,Colasacco C,Lacchetti C,Thomas NE

    更新日期:2015-12-01 00:00:00

  • Granular cell tumors of the breast. Steroid receptor analysis and localization of carcinoembryonic antigen, myoglobin, and S100 protein.

    abstract::Granular cell tumors occur in a variety of sites, including the breast (6%). Origins from histiocytic, myogenic, fibroblastic, and neurogenic elements have been proposed. Female predominance suggests that estrogenic hormones are involved. Four granular cell tumors of the breast and one in an axillary lymph node were s...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Ingram DL,Mossler JA,Snowhite J,Leight GS,McCarty KS Jr

    更新日期:1984-11-01 00:00:00

  • Lymph node involvement by histiocytosis X.

    abstract::Lymph node involvement by histiocytosis X is usually secondary to nearby bone or skin lesions. A patient with histiocytosis X confined to lymph nodes is rarely seen; however, we studied two such persons. In each, a lymph node biopsy was performed because the clinical aspects caused us to suspect neoplastic disease. ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Sajjad SM,Osborne B

    更新日期:1982-02-01 00:00:00

  • Oligonucleotide probing. Applications to HLA typing.

    abstract::Human leukocyte antigen typing is currently being done by both serologic and cellular techniques. It is this methodology that forms the basis for organ transplantation, since HLA antigens are the major proteins involved in graft rejection. Matching organ graft donors with recipients at these polymorphic HLA loci clear...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Freeman SM,Noreen HJ,Bach FH

    更新日期:1988-01-01 00:00:00

  • Primary basal cell carcinoma of the nipple.

    abstract::Basal cell carcinoma arising from the nipple of the breast is an uncommon malignancy, with only a handful of cases reported in the literature. The diagnosis is, however, important because basal cell carcinoma in this location can mimic breast cancer, may behave aggressively, and there is a relative lack of consensus i...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/1543-2165(2004)128<792:PBCCOT>2.0.CO;2

    authors: Gupta C,Sheth D,Snower DP

    更新日期:2004-07-01 00:00:00

  • Pathologic correlation in mammographically directed breast biopsies.

    abstract::In a series of 1137 diagnostic breast biopsy specimens in a 2-year period, nearly half (n = 534) underwent specimen mammography. Calcifications were found in 48% of the specimen mammograms. In a quarter of the cases, calcification was a marker either for carcinoma or a significant precursor lesion. Moreover, in the ma...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Symonds DA,Copeland BE,Drane A,Kaplan GN,Graham RR

    更新日期:1992-01-01 00:00:00