Selective myocardial cell necrosis in nonhuman primates.

Abstract:

:A retrospective study was performed to describe the histologic stages of selective myocardial cell necrosis (SMCN) in nonhuman primates, and to compare the incidence of SMCN in two groups of nonhuman primates. Myocardial tissues taken at the time of autopsy from 50 primates at an experimental center were compared with similar tissues from 50 primates housed in a breeding colony. SMCN was confirmed in 20% of the experimental primates and 30% of the breeding primates, proportions that were not significantly different. The incidence and histologic characteristics of SMCN in nonhuman primates were similar to those described in humans, and resembled the lesion produced in experimental primates by administration of catecholamines of by hypokalemia.

journal_name

Arch Pathol Lab Med

authors

Cowan MJ,Giddens WE Jr,Reichenbach DD

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

34-9

issue

1

eissn

0003-9985

issn

1543-2165

journal_volume

107

pub_type

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