Diagnostic problems with trophoblastic lesions.

abstract：:Granular cell tumors are benign lesions that usually appear in the skin, oral activity, and mucous membrane. Occasionally, they will appear in visceral organs, and cause signs and symptoms similar to those of other organ-related diseases. We studied a patient with granular cell tumors of the common bile duct whose cli...

journal_title：Archives of pathology & laboratory medicine

authors： Aisner SC,Khaneja S,Ramirez O

更新日期：1982-09-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma is a nodal peripheral T-cell lymphoma that rarely involves the skin. We describe a 62-year-old Taiwanese man who developed a second relapse of angioimmunoblastic T-cell lymphoma with generalized erythroderma and numerous plaquelike and nodular lesions. Biopsy of the erythematous skin...

journal_title：Archives of pathology & laboratory medicine

authors： Huang CT,Chuang SS

更新日期：2004-10-01 00:00:00

abstract：CONTEXT:c-kit, a proto-oncogene, encodes the transmembrane tyrosine kinase receptor CD117 and is detected by flow cytometry in the majority of cases of acute myeloid leukemia. The prognostic significance of the presence of c-Kit in acute myeloid leukemia is debated. Recently, c-kit inhibitors have been studied as possi...

journal_title：Archives of pathology & laboratory medicine

authors： Chen J,Yanuck RR 3rd,Abbondanzo SL,Chu WS,Aguilera NS

更新日期：2001-11-01 00:00:00

abstract：:To understand better the intracellular iron distribution and metabolic consequences of chronic hepatic iron overload, rats were given large doses of iron dextran or ferric citrate intraperitoneally. They accumulated large quantities of iron within Kupffer cells and hepatocytes. The relative subcellular iron distributi...

journal_title：Archives of pathology & laboratory medicine

authors： Bonkowsky HL,Carpenter SJ,Healey JF

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:The major biochemical characteristic of Dupuytren disease is the progressive and irreversible deposition of excess fibrous collagen characterized by an enhanced type III collagen proportion. OBJECTIVE:To investigate the influence of changes of the collagen spectrum on the biophysical properties of the palma...

journal_title：Archives of pathology & laboratory medicine

authors： Melling M,Karimian-Teherani D,Mostler S,Behnam M,Sobal G,Menzel EJ

更新日期：2000-09-01 00:00:00

abstract：:The spirochete, Treponema pallidum, the causative agent of syphilis, has been successfully localized in formaldehydefixed and paraffin-embedded tissue sections using rabbit anti-T pallidum antiserum with two immunoperoxidase techniques. These techniques, the indirect peroxidase-labeled antibody method and the peroxida...

journal_title：Archives of pathology & laboratory medicine

authors： Beckett JH,Bigbee JW

更新日期：1979-03-01 00:00:00

abstract：CONTEXT:Clinical laboratory specimens may be rejected as unsuitable for analysis for a variety of reasons and specimen rejection may have significant clinical consequences. OBJECTIVE:To quantify the clinical consequences of specimen rejection and determine the impact of laboratories' policies and practices on these co...

journal_title：Archives of pathology & laboratory medicine

authors： Karcher DS,Lehman CM

更新日期：2014-08-01 00:00:00

abstract：:Immunoreactivity for endocrine peptides (serotonin, gastrin, somatostatin, insulin, corticotropin, calcitonin, neurotensin, vasoactive intestinal peptide, and bombesin), cytoskeletal proteins (high and low molecular weight keratins), and tumor differentiation markers (chromogranin, neuron-specific enolase, carcinoembr...

journal_title：Archives of pathology & laboratory medicine

authors： Ulich TR,Liao SY,Layfield L,Romansky S,Cheng L,Lewin KJ

更新日期：1986-11-01 00:00:00

abstract：:Mucosa-associated lymphoid tissue (MALT) lymphomas are low-grade B-cell lymphomas that occur in a variety of extranodal sites but rarely as a primary hepatic lymphoma. We describe the histological findings, immunophenotype, and immunohistochemistry of one such lymphoma found incidentally in a 69-year-old woman. The ly...

journal_title：Archives of pathology & laboratory medicine

authors： Kirk CM,Lewin D,Lazarchick J

更新日期：1999-08-01 00:00:00

abstract：CONTEXT:Lung cancer is the number one cause of cancer deaths in the United States and globally. The advent of targeted therapies has offered a new treatment paradigm for lung cancer, but currently validated and emerging drugs are effective in only a small minority of lung cancers, predominantly adenocarcinomas. Folate ...

journal_title：Archives of pathology & laboratory medicine

authors： Cagle PT,Zhai QJ,Murphy L,Low PS

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To study the immunoreactivity profile of the neuron-associated class III beta-tubulin isotype (beta III) in epithelial lung tumors. DESIGN:One hundred four formalin-fixed, paraffin-embedded primary and metastatic lung cancer specimens were immunostained with an anti-beta III mouse monoclonal antibody (TuJ1) ...

journal_title：Archives of pathology & laboratory medicine

authors： Katsetos CD,Kontogeorgos G,Geddes JF,Herman MM,Tsimara-Papastamatiou H,Yu Y,Sakkas LI,Tsokos M,Patchefsky AS,Ehya H,Cooper HS,Provencio J,Spano AJ,Frankfurter A

更新日期：2000-04-01 00:00:00

abstract：CONTEXT:Aperio Technologies, Inc (Vista, California) provides a new immunohistochemistry (IHC) HER2 Image Analysis (IA) system that allows tuning of the intensity thresholds of the HER2/ neu scoring scheme to adapt to the staining characteristics of different reagents. OBJECTIVE:To compare the trainable IHC HER2 IA sy...

journal_title：Archives of pathology & laboratory medicine

authors： Nassar A,Cohen C,Agersborg SS,Zhou W,Lynch KA,Albitar M,Barker EA,Vanderbilt BL,Thompson J,Heyman ER,Lange H,Olson A,Siddiqui MT

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:Barrett esophagus is a metaplastic, premalignant lesion associated with approximately 0.5% annual incidence of progression to esophageal adenocarcinoma. Diagnosis and screening of Barrett esophagus and Barrett-related dysplasia relies on histologic evaluation of endoscopic mucosal biopsies, a process that is bu...

journal_title：Archives of pathology & laboratory medicine

authors： Voltaggio L,Montgomery EA,Lam-Himlin D

更新日期：2011-10-01 00:00:00

abstract：CONTEXT.—:Nodal metastasis of a primary tumor influences therapy decisions for a variety of cancers. Histologic identification of tumor cells in lymph nodes can be laborious and error-prone, especially for small tumor foci. OBJECTIVE.—:To evaluate the application and clinical implementation of a state-of-the-art deep ...

journal_title：Archives of pathology & laboratory medicine

authors： Liu Y,Kohlberger T,Norouzi M,Dahl GE,Smith JL,Mohtashamian A,Olson N,Peng LH,Hipp JD,Stumpe MC

更新日期：2019-07-01 00:00:00

abstract：:Silicone breast prostheses are medical devices, implanted subcutaneously or subpectorally, that are designed to replace or augment the volume occupied by breast glandular tissue. They are generally effective in creating tissue mounds, and their apparent medical benefit is primarily psychological. Recent data on immuno...

journal_title：Archives of pathology & laboratory medicine

authors： Kossovsky N,Freiman CJ

更新日期：1994-07-01 00:00:00

abstract：:Recent reports have elucidated the variety of tissue types that can react with HMB-45. Consistent positivity has been demonstrated in angiomyolipomas, but only in the smooth-muscle cells. In this report, we examine five renal angiomyolipomas and 20 mesenchymal lesions with similar morphological features and with a pos...

journal_title：Archives of pathology & laboratory medicine

authors： Hoon V,Thung SN,Kaneko M,Unger PD

更新日期：1994-07-01 00:00:00

abstract：CONTEXT.—:Ossifying fibromyxoid tumor (OFMT) is a rare, slow-growing mesenchymal neoplasm of uncertain histogenesis with intermediate malignant potential. OBJECTIVE.—:To highlight the most important diagnostic features, including morphologic, immunohistochemical, and molecular findings; to provide comparisons to other...

journal_title：Archives of pathology & laboratory medicine

authors： Carter CS,Patel RM

更新日期：2019-12-01 00:00:00

abstract：:A T-cell immunoblastic lymphoma having plasmacytoid features that mimic B-cell immunoblastic lymphoma, is described. The lesion was composed of sheets of pleomorphic plasmacytoid cells that displayed a helper T-cell immunophenotype (Leu-1+, Leu-3+, Leu-4+, Leu-5+, Leu-9-, Leu-2-). Ultrastructural features were consist...

journal_title：Archives of pathology & laboratory medicine

authors： Swanson S,Innes DJ Jr,Frierson HF Jr,Hess CE

更新日期：1987-11-01 00:00:00

abstract：:Human parvovirus B19 is a single-stranded DNA virus with a predilection for infecting rapidly dividing cell lines, such as bone marrow erythroid progenitor cells. People with defective cell-mediated immunity (eg, severe combined immunodeficiency syndrome; acquired immunodeficiency syndrome; and patients receiving immu...

journal_title：Archives of pathology & laboratory medicine

authors： Florea AV,Ionescu DN,Melhem MF

更新日期：2007-05-01 00:00:00

abstract：CONTEXT:Because the consequences of making an interpretive error on a proficiency test are more severe than those made on an educational challenge, the same slide may exhibit different performance characteristics in the 2 different settings. OBJECTIVE:The results of the 2006 College of American Pathologists Gynecologi...

journal_title：Archives of pathology & laboratory medicine

authors： Hughes JH,Bentz JS,Fatheree L,Souers RJ,Wilbur DC,Cytopathology Resource Committee, College of American Pathologists.

更新日期：2009-02-01 00:00:00

abstract：:In 112 patients with mixed tumors of the salivary glands, 94 tumors were located in parotid glands, 11 in submandibular salivary glands, and 7 in monor palatal salivary glands. Capsular ingrowth, a characteristic growth pattern, may explain the frequency of multilobulation and capsular defects in these tumors, particu...

journal_title：Archives of pathology & laboratory medicine

authors： Naeim F,Forsberg MI,Waisman J,Coulson WF

更新日期：1976-05-01 00:00:00

abstract：:Ergotamine has been associated with numerous vascular complications but only rarely with fibrosing disorders or valvular heart disease. Two patients are described in whom severe valvular dysfunction developed during ergotamine therapy for migraine headache. The surgically excised mitral and aortic valves were involved...

journal_title：Archives of pathology & laboratory medicine

authors： Hauck AJ,Edwards WD,Danielson GK,Mullany CJ,Bresnahan DR

更新日期：1990-01-01 00:00:00

abstract：:Sarcoidosis is a chronic systemic disease of unknown etiology, which is characterized by noncaseating epitheloid granulomas usually in multiple organs. Here we describe changes in cytokine mRNA expression by peripheral blood mononuclear cells (PBMCs) and changes of cytokine protein levels in plasma over a time course ...

journal_title：Archives of pathology & laboratory medicine

authors： Schoppet M,Pankuweit S,Maisch B

更新日期：2003-09-01 00:00:00

abstract：:Distinctive globular bodies, ranging in diameter from 0.2mu to 1.5mu, were encountered in the cytoplasm of epithelial cells of human rectal mucosa. These profiles, surrounded by a unit membrane, contained a uniform population of electron-dense rods 50 nm wide and 100 to 250 nm long. Although neither the origin nor the...

journal_title：Archives of pathology & laboratory medicine

authors： Biempica L,Sternlieb I,Sohn HB,Ali M

更新日期：1976-02-01 00:00:00

abstract：:Hepatoid carcinoma of the ovary (HCO) is a rare malignant tumor of uncertain histogenesis that was first described by Ishikura and Scully in the late 1980s. Unlike hepatoid yolk sac tumor (HYST), one of its main differential diagnoses, HCO usually presents in perimenopausal and postmenopausal women without gonadal dys...

journal_title：Archives of pathology & laboratory medicine

authors： Acosta AM,Pins MR

更新日期：2019-07-01 00:00:00

abstract：CONTEXT:Angiosarcomas are rare malignancies that commonly arise in the head and neck. No definitive precursor lesion or etiological link between hemangiomas and angiosarcoma has been postulated. Evidence at the cell culture level suggests that loss of heterozygosity of 13q might be involved in tumorigenesis of endothel...

journal_title：Archives of pathology & laboratory medicine

authors： Domfeh AB,Fichera M,Hunt JL

更新日期：2006-08-01 00:00:00

abstract：:Laboratories participating in the College of American Pathologists Enzyme Survey (ES) and Comprehensive Chemistry Survey used diverse methods for the same analyte, resulting in a considerable range of values for the commonly performed enzyme measurements. Nevertheless, with the techniques developed for the ES, both th...

journal_title：Archives of pathology & laboratory medicine

authors： Lott JA,Tholen DW,Massion CG

更新日期：1988-04-01 00:00:00

abstract：CONTEXT:-Immunohistochemical analysis of tissue biopsy specimens is a crucial tool in diagnosis of both rejection and infection in patients with solid organ transplants. In the past 15 years, the concept of antibody-mediated rejection has been refined, and diagnostic criteria have been codified in renal, heart, pancrea...

journal_title：Archives of pathology & laboratory medicine

authors： Troxell ML,Lanciault C

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To investigate ras gene alteration in human gastric adenocarcinomas and its potential relationship to ras signal transduction mediators. DESIGN:Genomic DNA from 104 gastric tumors were analyzed by sequencing of polymerase chain reaction-amplified products for the presence of ras mutations. All the samples we...

journal_title：Archives of pathology & laboratory medicine

authors： Yoo J,Park SY,Robinson RA,Kang SJ,Ahn WS,Kang CS

更新日期：2002-09-01 00:00:00

abstract：:We have developed an inexpensive, microcomputer-based, multiuser hard disk system for surgical pathology that uses a commercially available word processor and data base manager, linked together by several BASIC programs written by us. System functions include keyboard input of patient demographic data and specimen inf...

journal_title：Archives of pathology & laboratory medicine

authors： Talamo TS,Losos FJ 3rd

更新日期：1985-01-01 00:00:00