Mitral and aortic valve disease associated with ergotamine therapy for migraine. Report of two cases and review of literature.

Abstract:

:Ergotamine has been associated with numerous vascular complications but only rarely with fibrosing disorders or valvular heart disease. Two patients are described in whom severe valvular dysfunction developed during ergotamine therapy for migraine headache. The surgically excised mitral and aortic valves were involved by a proliferative process that was strikingly similar to lesions described in patients with carcinoid heart disease and methysergide-associated valvular disease.

journal_name

Arch Pathol Lab Med

authors

Hauck AJ,Edwards WD,Danielson GK,Mullany CJ,Bresnahan DR

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

62-4

issue

1

eissn

0003-9985

issn

1543-2165

journal_volume

114

pub_type

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