Immunohistochemical localization of apoprotein B in aortas from hyperlipemic swine. Preferential accumulation in lesion-prone areas.

abstract：:Frozen section is a prominent point of intersection between surgeons and pathologists. It is regarded as the most definitive--but not the sole--form of intraoperative consultation. Its role in tissue triage, diagnosis, and intraoperative management should not be misconstrued as a shortcut to a definitive diagnosis. Al...

journal_title：Archives of pathology & laboratory medicine

authors： Taxy JB

更新日期：2009-07-01 00:00:00

abstract：:A dyserythropoietic syndrome with coincidental immune thrombocytopenia seen during pregnancy is discussed. The morphological and serological results in this case most resemble type II congenital dyserythropoietic anemia. However, functional evidence of dyserythropoiesis was absent and the patient was not anemic. Splen...

journal_title：Archives of pathology & laboratory medicine

authors： Lillicrap DP,Corbett WE,Giles AR,Ginsburg AD

更新日期：1987-06-01 00:00:00

abstract：CONTEXT:KRAS mutations can be detected in approximately 30% to 40% of all patients with colorectal cancer. Several recent studies have shown that patients with KRAS mutations in codons 12 or 13 in metastatic tumors do not benefit from anti-epidermal growth factor receptor therapy with cetuximab or panitumumab. OBJECTI...

journal_title：Archives of pathology & laboratory medicine

authors： Monzon FA,Ogino S,Hammond ME,Halling KC,Bloom KJ,Nikiforova MN

更新日期：2009-10-01 00:00:00

abstract：:Laboratories contemplating either the addition of new molecular tests or modifying methods approved by the Food and Drug Administration for human papillomavirus testing should be aware of a variety of procedural, performance, and regulatory issues surrounding such activity. Diagnostic medical laboratory testing in the...

journal_title：Archives of pathology & laboratory medicine

authors： Seabrook JM,Hubbard RA

更新日期：2003-08-01 00:00:00

abstract：:The incidence of systemic candidiasis appears to be on the rise, and unusual or hitherto undocumented clinicopathologic features of invasive candidiasis continue to be described. This report adds further to this spectrum by describing granulomatous appendicitis due to invasive candidiasis. The patient was a 23-year-ol...

journal_title：Archives of pathology & laboratory medicine

authors： Moyana TN,Kulaga A,Xiang J

更新日期：1996-02-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma is a nodal peripheral T-cell lymphoma that rarely involves the skin. We describe a 62-year-old Taiwanese man who developed a second relapse of angioimmunoblastic T-cell lymphoma with generalized erythroderma and numerous plaquelike and nodular lesions. Biopsy of the erythematous skin...

journal_title：Archives of pathology & laboratory medicine

authors： Huang CT,Chuang SS

更新日期：2004-10-01 00:00:00

abstract：:Reported is an instance of bronchiolitis obliterans due to the accumulation of lipid-laden cells within bronchiolar walls and lumina. The bronchiolar lining had extensive squamous and goblet cell metaplasia with focal ulceration. Scattered foci of cholesterol pneumonia, composed of acicular crystals with an associated...

journal_title：Archives of pathology & laboratory medicine

authors： Heffelfinger SC,Weilbaecher DG,Lawrence EC,Johnson EH,Greenberg SD

更新日期：1988-06-01 00:00:00

abstract：CONTEXT:The unprecedented advances in cancer genetics and genomics are rapidly affecting clinical management and diagnostics in solid tumor oncology. Molecular diagnostics is now an integral part of routine clinical management in patients with lung, colon, and breast cancer. In sharp contrast, molecular biomarkers have...

journal_title：Archives of pathology & laboratory medicine

authors： Netto GJ,Cheng L

更新日期：2012-04-01 00:00:00

abstract：:To our knowledge, there are currently no reports in the literature that discuss the fine structure of the striated ducts of the human parotid gland. Papillary cystadenoma lymphomatosum (Warthin's tumor) is a benigh neoplasm found almost exclusively in the parotid gland that represents about 16% of all neoplasms of the...

journal_title：Archives of pathology & laboratory medicine

authors： Cutler LS,Chaudhry A,Innes DJ Jr

更新日期：1977-08-01 00:00:00

abstract：OBJECTIVE:Pseudosarcomatous myofibroblastic tumors (PMTs) of the urogenital tract are rare but distinctive lesions. Despite their benign behavior, they are frequently misinterpreted as leiomyosarcomas and rhabdomyosarcomas in preoperative biopsies and even in resected specimens because of their atypical spindle-cell fe...

journal_title：Archives of pathology & laboratory medicine

authors： Watanabe K,Baba K,Saito A,Hoshi N,Suzuki T

更新日期：2001-08-01 00:00:00

abstract：CONTEXT:Recent discoveries have expanded the spectrum of nonneoplastic pulmonary lymphoproliferative disorders and have provided new insights into their pathogenesis and treatment. OBJECTIVE:To review the thoracic manifestations of immunoglobulin (Ig) G4-related sclerosing disease and summarize current concepts and di...

journal_title：Archives of pathology & laboratory medicine

authors： Guinee DG Jr

更新日期：2010-05-01 00:00:00

abstract：CONTEXT:-Multiple sources have identified challenges that training programs face in preparing graduates for the "real world" practice of pathology, and many training programs have sought to decrease the gap between skills acquired during training and those required in practice. However, there exists the possibility tha...

journal_title：Archives of pathology & laboratory medicine

authors： Post MD,Johnson K,Brissette MD,Conran RM,Domen RE,Hoffman RD,McCloskey CB,Raciti PM,Roberts CA,Rojiani AM,Tucker JA,Powell SZ

更新日期：2017-02-01 00:00:00

abstract：:Placental mesenchymal dysplasia is a rare placental lesion characterized by stem villous cystic dilation and vesicle formation, placentomegaly, and vascular abnormalities. It can be associated with growth restriction, stillbirth, Beckwith-Wiedemann syndrome, and some chromosomal abnormalities, and needs to be distingu...

journal_title：Archives of pathology & laboratory medicine

authors： Pawoo N,Heller DS

更新日期：2014-09-01 00:00:00

abstract：:Adult T-cell leukemia/lymphoma is a monoclonal T-cell neoplasm associated with human T-cell lymphotropic virus-1 (HTLV-1) that occurs almost exclusively in adults. This report concerns a Romanian girl who had recurrent skin eruptions since infancy, subcutaneous tumors in childhood, and peripheral blood lymphocytosis, ...

journal_title：Archives of pathology & laboratory medicine

authors： Lin BT,Musset M,Székely AM,Alexandre J,Fraitag S,Bodemer C,Charpentier A,Frenoy N,Misset JL,Medeiros LJ,Rappaport H

更新日期：1997-12-01 00:00:00

abstract：CONTEXT:- Pathologists routinely assess Ki67 immunohistochemistry to grade gastrointestinal and pancreatic neuroendocrine tumors. Unfortunately, manual counts of the Ki67 index are very time consuming and eyeball estimation has been criticized as unreliable. Manual Ki67 counts performed by cytotechnologists could poten...

journal_title：Archives of pathology & laboratory medicine

authors： Cottenden J,Filter ER,Cottreau J,Moore D,Bullock M,Huang WY,Arnason T

更新日期：2018-03-01 00:00:00

abstract：CONTEXT:There are virtually no data in the literature regarding the incidence, patterns, and clinicopathologic characteristics of mucinous carcinomas (MCs) of the gallbladder (GB). OBJECTIVE:To determine the incidence of mucinous differentiation in invasive GB carcinomas and the clinicopathologic characteristics of th...

journal_title：Archives of pathology & laboratory medicine

authors： Dursun N,Escalona OT,Roa JC,Basturk O,Bagci P,Cakir A,Cheng J,Sarmiento J,Losada H,Kong SY,Ducato L,Goodman M,Adsay NV

更新日期：2012-11-01 00:00:00

abstract：:We describe an infarcted mass in the testis containing "ghost" cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplasti...

journal_title：Archives of pathology & laboratory medicine

authors： Florentine BD,Roscher AA,Garrett J,Warner NE

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:To identify resources and summarize important issues in anatomic and clinical pathology training and to assist the pathology resident candidate in evaluating potential training programs. DATA SOURCES:Published guides for medical residency applicants, recent literature discussing pathology education, and Wor...

journal_title：Archives of pathology & laboratory medicine

authors： Yorke RF

更新日期：2000-06-01 00:00:00

abstract：CONTEXT:Impairment of venous outflow manifests as zone 3 sinusoidal dilatation and congestion (SDC) in liver biopsy. However, the finding of SDC is not specific for venous outflow impairment.Objectives.-To determine the specificity of SDC in liver biopsies for venous outflow impairment and to seek an explanation for SD...

journal_title：Archives of pathology & laboratory medicine

authors： Kakar S,Kamath PS,Burgart LJ

更新日期：2004-08-01 00:00:00

abstract：CONTEXT:CDX2, a critical nuclear transcription factor for intestinal development, is expressed in intestinal epithelium and adenocarcinomas. OBJECTIVES:To determine if CDX2 is a useful marker for intestinal-type differentiation and to correlate tumor histology with CDX2 staining in colorectal adenocarcinomas. DESIGN:...

journal_title：Archives of pathology & laboratory medicine

authors： De Lott LB,Morrison C,Suster S,Cohn DE,Frankel WL

更新日期：2005-09-01 00:00:00

abstract：:Pulmonary and renal infection developed in a 44-year-old Hispanic man due to the fungus Pseudallescheria boydii. Pseudallescheria boydii has been associated with cutaneous infection known as mycetoma but occurs very infrequently in extracutaneous sites. To our knowledge, this is the second reported case of P boydii in...

journal_title：Archives of pathology & laboratory medicine

authors： Scherr GR,Evans SG,Kiyabu MT,Klatt EC

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:A full autopsy at our institution includes removal of the eyes for pathologic examination. To our knowledge, the rate of ophthalmic findings at autopsy has not been documented previously. DESIGN:We retrospectively reviewed 277 consecutive autopsies conducted between 1995 and 1999 in which the eyes were remo...

journal_title：Archives of pathology & laboratory medicine

authors： Butnor KJ,Proia AD

更新日期：2001-09-01 00:00:00

abstract：:Sarcoidlike granulomas may occur in association with Hodgkin lymphoma and non-Hodgkin lymphoma. The granulomas may be concomitant and so extensive that they obscure the malignant process. In addition, a sarcoidosis-lymphoma syndrome has been described in which there appears to be a relationship between sarcoidosis and...

journal_title：Archives of pathology & laboratory medicine

authors： Dunphy CH,Panella MJ,Grosso LE

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To determine the diagnostic accuracy of an investigational test for human immunodeficiency virus (HIV) envelope antibodies in urine. DESIGN:Matched blood and urine specimens were tested for HIV by two independent laboratories, both of which were blinded to all results at the other site. Duplicate positive en...

journal_title：Archives of pathology & laboratory medicine

authors： Berrios DC,Avins AL,Haynes-Sanstad K,Eversley R,Woods WJ

更新日期：1995-02-01 00:00:00

abstract：:We report the clinical and postmortem findings in a newborn with Beckwith-Wiedemann syndrome and pulmonary hypoplasia. The infant was found to have a massively enlarged thymus gland that apparently caused pulmonary hypoplasia and respiratory insufficiency. Massive hyperplasia of the thymus gland should be considered i...

journal_title：Archives of pathology & laboratory medicine

authors： Balcom RJ,Hakanson DO,Werner A,Gordon LP

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVES:To review the state of the art relating to elevated hemostatic factor levels as a potential risk factor for thrombosis, as reflected by the medical literature and the consensus opinion of recognized experts in the field, and to make recommendations for the use of specific measurements of hemostatic factor le...

journal_title：Archives of pathology & laboratory medicine

authors： Chandler WL,Rodgers GM,Sprouse JT,Thompson AR

更新日期：2002-11-01 00:00:00

abstract：:A spectrum of changes that range from crypt basophilia through varying degrees of dysplasia and carcinoma in situ have been observed in the flat, nonraised mucosa of the rectum in patient who received pelvic irradiation for carcinoma of the cervix. This case demonstrates (1) the morphological evidence of the relations...

journal_title：Archives of pathology & laboratory medicine

authors： Shamsuddin AK,Elias EG

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVE:To study the expression of thyroid transcription factor 1 (TTF-1) and cytokeratin 20 (CK20) in pulmonary small cell carcinomas, extrapulmonary small cell carcinomas, and Merkel cell carcinomas, and thereby determine whether these markers are helpful in distinguishing these 3 groups of small cell neuroendocrin...

journal_title：Archives of pathology & laboratory medicine

authors： Cheuk W,Kwan MY,Suster S,Chan JK

更新日期：2001-02-01 00:00:00

abstract：CONTEXT:Myelodysplastic syndromes (MDSs) are clonal stem cell diseases characterized by ineffective hematopoiesis, multilineage dysplasia, and peripheral cytopenias with normocellular or hypercellular marrow. They represent a heterogeneous group of disorders with a varied spectrum of clinical, morphologic, biologic, an...

journal_title：Archives of pathology & laboratory medicine

authors： Nishino HT,Chang CC

更新日期：2005-10-01 00:00:00

abstract：CONTEXT:Lesions associated with monoclonal light and heavy chains display a variety of glomerular, tubular interstitial, and vascular manifestations. While some of the entities are well recognized, including light and heavy chain deposition diseases, AL (light chain) and AH (heavy chain) amyloidosis, and light chain ("...

journal_title：Archives of pathology & laboratory medicine

authors： Herrera GA

更新日期：2014-10-01 00:00:00