Pseudosarcomatous myofibroblastic tumor and myosarcoma of the urogenital tract.

Abstract:

OBJECTIVE:Pseudosarcomatous myofibroblastic tumors (PMTs) of the urogenital tract are rare but distinctive lesions. Despite their benign behavior, they are frequently misinterpreted as leiomyosarcomas and rhabdomyosarcomas in preoperative biopsies and even in resected specimens because of their atypical spindle-cell features. Precise diagnosis of PMTs is important to avoid unnecessary radical therapy. We analyzed urogenital myoid tumors to clarify which of their characteristics are useful for the differential diagnosis. METHODS:We evaluated 7 urogenital myoid tumors consisting of 3 PMTs, 2 leiomyosarcomas, and 2 rhabdomyosarcomas. We studied the expression of various immunohistochemical muscle-cell markers including desmin, muscle-specific actin, alpha-smooth muscle actin, high-molecular-weight caldesmon, and myogenin. RESULTS:Desmin, muscle-specific actin, and alpha-smooth muscle actin were noted variably in all tumor types, whereas high-molecular-weight caldesmon was expressed only in leiomyosarcomas, and myogenin was expressed only in rhabdomyosarcomas. CONCLUSION:High-molecular-weight caldesmon and myogenin are useful for differentiating urogenital PMTs from myosarcomas.

journal_name

Arch Pathol Lab Med

authors

Watanabe K,Baba K,Saito A,Hoshi N,Suzuki T

doi

10.1043/0003-9985(2001)125<1070:PMTAMO>2.0.CO;2

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

1070-3

issue

8

eissn

0003-9985

issn

1543-2165

journal_volume

125

pub_type

杂志文章
  • Embolism of brain tissue to the lung in a neonate. Report of a case and review of the literature.

    abstract::Embolic cerebellar tissue was observed microscopically in the pulmonary and coronary arteries of a full-term male infant who died 1 hour after forceps delivery. Although embolization of brain tissue has been well documented after severe head trauma in adults and children, to our knowledge only 17 cases associated with...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Hauck AJ,Bambara JF,Edwards WD

    更新日期:1990-02-01 00:00:00

  • Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents.

    abstract:CONTEXT:Lung cancer is the number one cause of cancer deaths in the United States and globally. The advent of targeted therapies has offered a new treatment paradigm for lung cancer, but currently validated and emerging drugs are effective in only a small minority of lung cancers, predominantly adenocarcinomas. Folate ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2012-0176-OA

    authors: Cagle PT,Zhai QJ,Murphy L,Low PS

    更新日期:2013-02-01 00:00:00

  • Redesigned proficiency testing materials improve survey outcomes for prostate-specific antigen. A College of American Pathologists Ligand Assay Survey tool.

    abstract:CONTEXT:Large disparities in prostate-specific antigen (PSA) results from different assays have been observed in the College of American Pathologists (CAP) Ligand Assay Survey, with interassay results varying severalfold. Survey specimens are predominately composed of free PSA and do not reflect the composition of typi...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2000)124<1608:RPTMIS>2.0.CO;2

    authors: Sokoll LJ,Witte DL,Klee GG,Chan DW

    更新日期:2000-11-01 00:00:00

  • Pancreatoblastoma in an adult.

    abstract::A 37-year-old man with a history of abdominal pain, diarrhea, and weight loss was found to have an 8-cm-diameter tumor in the head of the pancreas, a biopsy specimen of which revealed histologically and ultrastructurally typical pancreatoblastoma. The tumor was unresectable and demonstrated no response to chemotherapy...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Palosaari D,Clayton F,Seaman J

    更新日期:1986-07-01 00:00:00

  • Sclerosing angiomatoid nodular transformation of the spleen.

    abstract::Sclerosing angiomatoid nodular transformation (SANT) is a recently recognized nonneoplastic vascular lesion of the spleen with fewer than 30 cases described. Microscopically, SANT consists of multiple well-circumscribed vascular/angiomatoid nodules showing plump endothelial cell and extravasated erythrocytes. The nodu...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2007)131[974:SANTOT]2.0.CO;2

    authors: Awamleh AA,Perez-Ordoñez B

    更新日期:2007-06-01 00:00:00

  • Best practices in contemporary diagnostic immunohistochemistry: panel approach to hematolymphoid proliferations.

    abstract:CONTEXT:The complexities of diagnostic hematopathology in the modern era are well known, and even in this molecular era, immunophenotypic studies, together with routine histopathology, remain a critical component in the evaluation of many lymphoid proliferations. With numerous antibodies that can be used on routinely f...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/1543-2165-133.5.756

    authors: Garcia CF,Swerdlow SH

    更新日期:2009-05-01 00:00:00

  • Human anti-mouse antibodies.

    abstract::Human anti-mouse antibodies (HAMA) are human immunoglobulins with specificity for mouse immunoglobulins. This topic currently is of interest because of the increased use of monoclonal mouse antibodies as diagnostic reagents both for in vitro laboratory measurements and for in vivo imaging studies. Monoclonal mouse ant...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/0003-9985(2000)124<0921:HAMA>2.0.CO;2

    authors: Klee GG

    更新日期:2000-06-01 00:00:00

  • The Role of High-Risk Human Papilloma Virus Testing in the Surveillance of Cervical Cancer After Treatment.

    abstract:CONTEXT:Cervical cancer affects 12 000 women in the United States annually. However, despite its prevalence, there remains no good methodology to detect its recurrence. OBJECTIVE:To identify the role of cervicovaginal high-risk human papilloma virus (hr-HPV) testing in predicting cervical cancer recurrence. DESIGN:Th...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2014-0534-OA

    authors: Yu MC,Austin RM,Lin J,Beck T,Beriwal S,Comerci JT,Edwards RP,Sukumvanich P,Kelley J,Olawaiye AB

    更新日期:2015-11-01 00:00:00

  • Methylation profiles of multiple CpG island loci in extrahepatic cholangiocarcinoma versus those of intrahepatic cholangiocarcinomas.

    abstract:CONTEXT:CpG island hypermethylation is attracting attention because of its importance as a tumor marker and its potential mechanism for the development of human cancers. Extrahepatic cholangiocarcinoma has been poorly investigated with respect to CpG island hypermethylation, and the number of genes known to be methylat...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2007)131[923:MPOMCI]2.0.CO;2

    authors: Kim BH,Cho NY,Choi M,Lee S,Jang JJ,Kang GH

    更新日期:2007-06-01 00:00:00

  • The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.

    abstract:CONTEXT:In immunohistochemistry, nonstandardized antigen retrieval protocols and fluids, poor-quality antibodies, and the presence of endogenous biotin frequently lead to incorrect results. Recently, advanced reagents including bifunctional SkipDewax pretreatment solution (BSPS), rabbit monoclonal (RM) antibodies, and ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2007)131[1047:TCOBSP]2.0.CO;2

    authors: Wong SC,Chan JK,Lo ES,Chan AK,Wong MC,Chan CM,Lam MY,Chan AT

    更新日期:2007-07-01 00:00:00

  • Evaluating Mismatch Repair/Microsatellite Instability Status Using Cytology Effusion Specimens to Determine Eligibility for Immunotherapy.

    abstract:CONTEXT.—:The approval of pembrolizumab for treatment of patients with microsatellite instability-high (MSI-H) or mismatch repair-deficient (dMMR) advanced cancers has led to increased requests for MSI and/or MMR immunoperoxidase (IPOX) testing. Diagnoses for patients with advanced-stage cancer are frequently made from...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2019-0398-OA

    authors: Jacobi EM,Landon G,Broaddus RR,Roy-Chowdhuri S

    更新日期:2020-03-30 00:00:00

  • Atypical endocrine tumors of the lung.

    abstract::Seven malignant peripheral lung tumors that were diagnosed using light microscopy as large-cell carcinomas or as epidermoid or adenocarcinomas were studied by light and electron microscopic histochemistry. All tumors contained numerous dense-core granules. The cells were joined by desmosomes and contained well-develop...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: McDowell EM,Wilson TS,Trump BF

    更新日期:1981-01-01 00:00:00

  • Lipoprotein lipase.

    abstract::The activity of lipoprotein lipase in the vascular bed represents the major pathway by which triglyceride fatty acid is cleared from the plasma and made available to the epripheral tissues. Recent studies on the properties of the enzyme, both solubilized and membrane-bound have provided new information on the regulati...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Fielding CJ,Havel RJ

    更新日期:1977-05-01 00:00:00

  • Duodenal-Type Follicular Lymphoma: A Clinicopathologic Review.

    abstract::Duodenal-type follicular lymphoma (D-FL) is a newly recognized entity in the 2016 World Health Organization classification update. It has an immunophenotype similar to that of other FLs and usually carries the typical t(14;18)(q32;q21) translocation. However, unlike other FLs, D-FL is almost always diagnosed at a low ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/arpa.2016-0519-RS

    authors: Marks E,Shi Y

    更新日期:2018-04-01 00:00:00

  • Beta-endorphin, steroids, and prolactin. Immunoassay in breast cysts and blood.

    abstract::Circulating levels and cyst fluid concentrations of beta-endorphin (beta-EP), estradiol, progesterone, and prolactin were measured by radioimmunoassays in 10 premenopausal women with gross breast cysts. In addition, aspirates and frozen tissue sections from cystic lesions were investigated immunocytochemically for a p...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Schön HJ,Schurz B,Wenzl R,Knogler W,Kubista E

    更新日期:1993-03-01 00:00:00

  • Morphologic criteria for the diagnosis of prostatic adenocarcinoma in needle biopsy specimens. A study of 250 consecutive cases in a routine surgical pathology practice.

    abstract:CONTEXT:The diagnosis of prostate adenocarcinoma in needle core biopsy specimens is based on multiple diagnostic criteria and supportive features, most of which have been defined mainly from observations in transurethral resection and prostatectomy specimens. There is little information on the frequency with which diag...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2002)126<0554:MCFTDO>2.0.CO;2

    authors: Varma M,Lee MW,Tamboli P,Zarbo RJ,Jimenez RE,Salles PG,Amin MB

    更新日期:2002-05-01 00:00:00

  • Primitive neuroectodermal tumor of the lung.

    abstract::Primitive neuroectodermal tumors occur most frequently in bone and soft tissue but have been reported in other locations. Primary lung primitive neuroectodermal tumors without pleural or chest wall involvement are extremely rare. We present a case with immunohistochemical and ultrastructural studies and follow-up of t...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2001)125<0397:PNTOTL>2.0.CO;2

    authors: Kahn AG,Avagnina A,Nazar J,Elsner B

    更新日期:2001-03-01 00:00:00

  • Perfluorochemicals. Morphologic changes in infused liver, spleen, lung, and kidney of rabbits.

    abstract::Perfluorochemicals have been shown to have a high affinity for oxygen and therefore, have potential use in circumstances in which conventional blood transfusions are not possible. We examined by light and electron microscopy (EM) histologic changes in liver, spleen, lung, and kidney of rabbits each infused with 20 to ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Nanney L,Fink LM,Virmani R

    更新日期:1984-08-01 00:00:00

  • Myelodysplastic syndromes in children: a critical review of issues in the diagnosis and classification of 887 cases from 13 published series.

    abstract:CONTEXT:Pediatric myelodysplastic syndromes (MDSs) are uncommon disorders, which may be difficult to diagnose, particularly in the absence of increased blasts. Pediatric MDSs have several unique features including their association with inherited/constitutional disorders in approximately one third of patients. The clas...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/1543-2165(2007)131[1110:MSICAC]2.0.CO;2

    authors: Elghetany MT

    更新日期:2007-07-01 00:00:00

  • Intraoperative consultation/final diagnosis correlation: relationship to tissue type and pathologic process.

    abstract:CONTEXT:The correlation of the diagnosis made at intraoperative consultation (IC) with the final diagnosis is one of the cornerstones of quality assurance in the anatomic pathology laboratory. OBJECTIVE:To review correlation of IC diagnoses with final diagnoses during a 1-year period in a regionalized, multisite hospi...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2008)132[29:IFDCRT]2.0.CO;2

    authors: White VA,Trotter MJ

    更新日期:2008-01-01 00:00:00

  • Turnaround time for large or complex specimens in surgical pathology: a College of American Pathologists Q-Probes study of 56 institutions.

    abstract:CONTEXT:Turnaround time (TAT) for large or complex surgical pathology specimens is an indicator of efficiency in anatomic pathology and may affect coordination of patient care. OBJECTIVE:To establish benchmarks for TAT and to identify practice characteristics that may influence TAT. DESIGN:Participants in a 2012 Q-Pr...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2013-0671-CP

    authors: Volmar KE,Idowu MO,Souers RJ,Karcher DS,Nakhleh RE

    更新日期:2015-02-01 00:00:00

  • Employer Expectations for Newly Trained Pathologists: Report of a Survey From the Graduate Medical Education Committee of the College of American Pathologists.

    abstract:CONTEXT:-Multiple sources have identified challenges that training programs face in preparing graduates for the "real world" practice of pathology, and many training programs have sought to decrease the gap between skills acquired during training and those required in practice. However, there exists the possibility tha...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2015-0138-CP

    authors: Post MD,Johnson K,Brissette MD,Conran RM,Domen RE,Hoffman RD,McCloskey CB,Raciti PM,Roberts CA,Rojiani AM,Tucker JA,Powell SZ

    更新日期:2017-02-01 00:00:00

  • Analysis of brain weight. II. Adult brain weight in relation to body height, weight, and surface area.

    abstract::Analysis of 1,261 adult subjects, ages 25 to 80 years, showed that there is a positive relationship between the brain weight and the body dimensions. The brain weight, however, increases at a slower rate than the body dimensions. There is indication that only a small portion of the brain varies with variation in the b...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Ho KC,Roessmann U,Straumfjord JV,Monroe G

    更新日期:1980-12-01 00:00:00

  • MUC1 gene-derived glycoprotein assays for monitoring breast cancer (CA 15-3, CA 27.29, BR): are they measuring the same antigen?

    abstract:CONTEXT:There are 2 general types of assays measuring MUC1 gene-derived glycoprotein: assays for cancer antigen (CA) 15-3, which are sandwich assays, and assays for CA 27.29, which are competitive assays. These 2 types of assays measure slightly different parts of this tandem-repeat molecule. Across-method assay differ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2004)128<1131:MGGAFM>2.0.CO;2

    authors: Klee GG,Schreiber WE

    更新日期:2004-10-01 00:00:00

  • Preventing platelet-derived microparticle formation--and possible side effects-with prestorage leukofiltration of whole blood.

    abstract:CONTEXT:Platelet-derived microparticles (PDMPs) probably function in hemostasis, thrombosis, inflammation, and transfusion-related immunomodulation. OBJECTIVE:To compare PDMP levels of leukocyte-filtered and unfiltered whole blood during storage. DESIGN:Ten whole blood donations were collected and processed. Half of ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165-134.5.771

    authors: Sugawara A,Nollet KE,Yajima K,Saito S,Ohto H

    更新日期:2010-05-01 00:00:00

  • Multicentric metachronous pulmonary and intravagal paraganglioma: a case report with immunohistochemical findings.

    abstract::An unprecedented presentation of multicentric paraganglioma in a 48-year-old man is described. One of the paragangliomas, originally diagnosed as a carcinoid tumor, presented as a lung mass and was removed. Four years later, an intravagal paraganglioma was discovered. The lung and intravagal tumors had identical morph...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Medalie NS,Mendelsohn MG,Esposito M

    更新日期:1996-12-01 00:00:00

  • HMB-45 reactivity in renal angiomyolipoma and lymphangioleiomyomatosis.

    abstract::Recent reports have elucidated the variety of tissue types that can react with HMB-45. Consistent positivity has been demonstrated in angiomyolipomas, but only in the smooth-muscle cells. In this report, we examine five renal angiomyolipomas and 20 mesenchymal lesions with similar morphological features and with a pos...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Hoon V,Thung SN,Kaneko M,Unger PD

    更新日期:1994-07-01 00:00:00

  • Cardiac myxomas. An immunohistochemical study using endothelial, histiocytic, and smooth-muscle cell markers.

    abstract::Previous immunohistochemical studies of cardiac myxomas are few in number, limited in scope and, in part, discrepant. We studied the immunoreactivity of five cardiac myxomas for factor VIII-related antigen, Ulex europaeus agglutinin I, smooth-muscle myosin, alpha 1-antitrypsin, and alpha 1-antichymotrypsin. Positive s...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Landon G,Ordóñez NG,Guarda LA

    更新日期:1986-02-01 00:00:00

  • Primary choriocarcinoma of the lung in a man.

    abstract::A case of nongestational, extragonadal choriocarcinoma in a middle-aged man is described. Autopsy examination confirmed that the tumor originated in the lung. The trophoblastic origin of the tumor was documented by immunoperoxidase staining for human chorionic gonadotropin. ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Sullivan LG

    更新日期:1989-01-01 00:00:00

  • Papular spongiotic dermatitis of smallpox vaccination: report of 2 cases with review of the literature.

    abstract::We report 2 cases of nonspecific postvaccinial dermatitis following smallpox vaccination. The patients presented with diffuse, pruritic, erythematous macules and papules 11 days (case 1) and 7 days (case 2) following routine smallpox vaccination. Biopsies of the lesions demonstrated spongiotic dermatitis without evide...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2004)128<1173:PSDOSV>2.0.CO;2

    authors: Gaertner EM,Groo S,Kim J

    更新日期:2004-10-01 00:00:00