Immunoperoxidase localization of treponema pallidum: its use in formaldehyde-fixed and paraffin-embedded tissue sections.

Abstract:

:The spirochete, Treponema pallidum, the causative agent of syphilis, has been successfully localized in formaldehydefixed and paraffin-embedded tissue sections using rabbit anti-T pallidum antiserum with two immunoperoxidase techniques. These techniques, the indirect peroxidase-labeled antibody method and the peroxidase-antiperoxidase (PAP) method are compared for sensitivity and degree of nonspecific staining. Both offer substantial advantages over conventional silver-impregnation techniques, but the indirect peroxidase-labeled antibody method seems better, based on the intensity of staining and the simplicity of procedure.

journal_name

Arch Pathol Lab Med

authors

Beckett JH,Bigbee JW

subject

Has Abstract

pub_date

1979-03-01 00:00:00

pages

135-8

issue

3

eissn

0003-9985

issn

1543-2165

journal_volume

103

pub_type

杂志文章
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