Disparate urinary catecholamine patterns in secondary hypertension due to unique sequential development of pheochromocytoma and neuroblastoma.

Abstract:

:A 43-year-old white woman had a pheochromocytoma removed from her left adrenal gland, and one year later she developed a new left upper abdominal mass that was found to be a neuroblastoma. On both occasions, urinary vanillylmandelic acid level was elevated. However, urinary norepinephrine and epinephrine levels were increased only during the pheochromocytoma episode, while the urinary homovanillic acid level was elevated only when neuroblastoma developed. Despite a high suspicion of pheochromocytoma recurrence, the urinary catecholamine profile was suggestive of neuroblastoma, which was revealed by histopathologic analysis of the tumor tissue.

journal_name

Arch Pathol Lab Med

authors

Amodeo C,Perez J,Sturgill BC,Turner SM,Atuk NO

subject

Has Abstract

pub_date

1989-07-01 00:00:00

pages

800-2

issue

7

eissn

0003-9985

issn

1543-2165

journal_volume

113

pub_type

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