High-risk features and tumor differentiation in retinoblastoma: a retrospective histopathologic study.

abstract：CONTEXT:Fear that damaging information from autopsy may be introduced as evidence in lawsuits alleging medical malpractice is often cited as one factor contributing to the decline in autopsy rates. OBJECTIVE:To determine how autopsy information influences the outcome of medical malpractice litigation. DESIGN:We studi...

journal_title：Archives of pathology & laboratory medicine

authors： Bove KE,Iery C,Autopsy Committee, College of American Pathologists.

更新日期：2002-09-01 00:00:00

abstract：:Most mesenchymal tumors of the gastrointestinal tract are now referred to as gastrointestinal stromal tumors (GISTs). The tumors differ from ordinary leiomyomas and schwannomas in several respects: the GISTs typically express c-kit protein (CD117) and CD34, 30% to 50% of them are (often focally) positive for alpha-smo...

journal_title：Archives of pathology & laboratory medicine

authors： Lasota J,Carlson JA,Miettinen M

更新日期：2000-06-01 00:00:00

abstract：:Accurate assessment of tissues for hematolymphoid neoplasms requires an integrated multiparameter approach. Although morphologic examination by light microscopy remains the mainstay of initial assessment for hematolymphoid neoplasms, immunophenotypic analysis by immunohistochemistry and/or flow cytometry is essential ...

journal_title：Archives of pathology & laboratory medicine

authors： Li S,Jaye DL,Bradley KT,Zhang L,Saxe D,Deeb G,Hill CE,Mann KP

更新日期：2017-03-01 00:00:00

abstract：CONTEXT:Although most primary cancers of the lung carry a heavy mutational load and will potentially present many "nonself" antigens to the immune system, there are a wide range of possible mechanisms for tumors to avoid so-called immune surveillance. One such mechanism is the adoption of immune checkpoints to inhibit ...

journal_title：Archives of pathology & laboratory medicine

authors： Kerr KM,Nicolson MC

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To review the state of the art relating to elevated hemostatic factor levels as a potential risk factor for thrombosis, as reflected by the medical literature and the consensus opinion of recognized experts in the field, and to make recommendations for the use of specific measurements of hemostatic factor le...

journal_title：Archives of pathology & laboratory medicine

authors： Chandler WL,Rodgers GM,Sprouse JT,Thompson AR

更新日期：2002-11-01 00:00:00

abstract：:Extensive squamous metaplasia is described in a case of gynecomastia. Numerous ducts in all sections of breast tissue revealed multiple foci of squamous metaplasia, many of which included large, papillary excrescences of keratinizing squamous cells into duct lumens, with foci of dyskeratosis. Review of four years of g...

journal_title：Archives of pathology & laboratory medicine

authors： Gottfried MR

更新日期：1986-10-01 00:00:00

abstract：:The ability of the College of American Pathologists Microbiology Surveys subscriber laboratories to perform antimicrobial susceptibility testing accurately has improved slightly since 1984. Currently (1989 surveys), the accuracies for disk diffusion and minimum inhibitory concentration antimicrobial susceptibility tes...

journal_title：Archives of pathology & laboratory medicine

authors： Jones RN,Edson DC

更新日期：1991-05-01 00:00:00

abstract：:Yeast forms of Blastomyces dermatitidis typically range from 8 to 20 microm in largest diameter. We report a rare case of primary pulmonary blastomycosis with an unusual morphology, in which we found significant numbers of large yeast forms ranging from 30 to 35 microm in diameter. To our knowledge, this is only the s...

journal_title：Archives of pathology & laboratory medicine

authors： Hussain Z,Martin A,Youngberg GA

更新日期：2001-05-01 00:00:00

abstract：:We report a case of endometrial metaplasia of the endocervix, which was associated with tubal and squamous metaplasias. The similarity to normal endometrial glands and its benign nature should be recognized, and over-diagnosis of endocervical glandular dysplasia should be avoided. ...

journal_title：Archives of pathology & laboratory medicine

authors： Yeh IT,Bronner M,LiVolsi VA

更新日期：1993-07-01 00:00:00

abstract：:We report a case of fatal fibrosing peritonitis in a 28-year-old drug abuser. The extensive fibrosis, which was limited to the abdominal cavity, contained birefringent material. Silica was identified by spectrophotometric analysis. Silica is a component of talc (magnesium silicate) used as a drug filler. Relatively sm...

journal_title：Archives of pathology & laboratory medicine

authors： Castelli MJ,Armin AR,Husain A,Orfei E

更新日期：1985-08-01 00:00:00

abstract：:The fluorescent dye thioflavin T stains intensely the deposits in dense deposit disease and can be used for identification purposes. Comparison of thioflavin T staining with electron microscopy was carried out in 25 patients and showed excellent congruity. Thioflavin T is much easier to use, but is less specific than ...

journal_title：Archives of pathology & laboratory medicine

authors： Churg J,Duffy JL,Bernstein J

更新日期：1979-02-01 00:00:00

abstract：:The lymph nodes from 50 axillary node dissections were evaluated by light microscopy and immunohistochemistry for the presence of dermatopathic lymphadenitis-like histologic features. On the basis of hematoxylin-eosin-stained sections alone, a histologic continuum was observed ranging from minimal paracortical changes...

journal_title：Archives of pathology & laboratory medicine

authors： Gould E,Porto R,Albores-Saavedra J,Ibe MJ

更新日期：1988-11-01 00:00:00

abstract：:We recently encountered a unique case of follicular variant of papillary carcinoma arising in struma ovarii that contained numerous intrafollicular crystalloids. There was no evidence of capsular or vascular invasion or metastases, though the DNA content of the papillary carcinoma was aneuploid. In contrast, diploid D...

journal_title：Archives of pathology & laboratory medicine

authors： Ro JY,Sahin AA,el-Naggar AK,Ordonez NG,Mackay B,Llamas LL,Ayala AG

更新日期：1991-02-01 00:00:00

abstract：CONTEXT:More than 25 years ago, John G. Azzopardi described a distinctive intraepithelial neoplastic breast lesion, which he designated "clinging carcinoma in situ"; he considered it as another variant of ductal carcinoma in situ, an early lesion that can easily be missed because the changes are mainly cytologic rather...

journal_title：Archives of pathology & laboratory medicine

authors： Moinfar F

更新日期：2009-06-01 00:00:00

abstract：CONTEXT.—:Resection of breast carcinoma with adequate margins reduces the risk of local recurrence and reoperation. Tozuleristide (BLZ-100) is an investigational peptide-fluorophore agent that may aid in intraoperative tumor detection and margin assessment. In this study, fluorescence imaging was conducted ex vivo on g...

journal_title：Archives of pathology & laboratory medicine

authors： Dintzis SM,Hansen S,Harrington KM,Tan LC,Miller DM,Ishak L,Parrish-Novak J,Kittle D,Perry J,Gombotz C,Fortney T,Porenta S,Hales L,Calhoun KE,Anderson BO,Javid SH,Byrd DR

更新日期：2019-09-01 00:00:00

abstract：CONTEXT:Expert opinion is often used as a gold standard for gynecologic cytology in the evaluation of new technologies, in the legal setting, and in the validation of cases for use in educational programs and proficiency testing. However, the reliability of expert opinion alone in selecting slides of a specific cytodia...

journal_title：Archives of pathology & laboratory medicine

authors： Renshaw AA,Wang E,Mody DR,Wilbur DC,Davey DD,Colgan TJ,Cytopathology Resource Committee, College of American Pathologists.

更新日期：2005-05-01 00:00:00

abstract：:Patients with inherited or acquired immunodeficiency disorders are vulnerable to a broad spectrum of opportunistic infectious diseases, but a narrow spectrum of malignancies. These malignancies--B-cell lymphomas, Kaposi's sarcomas, and squamous cell carcinomas--are likely due to failure of immune surveillance to recog...

journal_title：Archives of pathology & laboratory medicine

authors： Purtilo DT

更新日期：1987-12-01 00:00:00

abstract：CONTEXT:Differences in participant responses for ThinPrep (TP) and non-ThinPrep (NTP) preparations for gastrointestinal cytology challenges, which circulated in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology (CAP NGC), may help to identify performance variations betwe...

journal_title：Archives of pathology & laboratory medicine

authors： Clayton AC,Bentz JS,Wasserman PG,Schwartz MR,Souers RJ,Chmara BA,Laucirica R,Clary KM,Moriarty AT,College of American Pathologists Cytopathology Resource Committee.

更新日期：2010-08-01 00:00:00

abstract：:We describe a young patient with no known family history of cancer who presented at 18 months with 2 advanced primary tumors, choroid plexus carcinoma and adrenal cortical carcinoma. Immunohistochemical studies demonstrated high levels of nuclear p53 protein expression in both tumors, as well as in the adjacent normal...

journal_title：Archives of pathology & laboratory medicine

authors： Wang L,Cornford ME

更新日期：2002-01-01 00:00:00

abstract：CONTEXT:Angiosarcomas are rare malignancies that commonly arise in the head and neck. No definitive precursor lesion or etiological link between hemangiomas and angiosarcoma has been postulated. Evidence at the cell culture level suggests that loss of heterozygosity of 13q might be involved in tumorigenesis of endothel...

journal_title：Archives of pathology & laboratory medicine

authors： Domfeh AB,Fichera M,Hunt JL

更新日期：2006-08-01 00:00:00

abstract：:A patient with a 17-month history of myelodysplastic syndrome (refractory anemia with excess blasts that evolved into chronic myelomonocytic leukemia), which was treated with transfusions and erythropoietin, developed abdominal and inguinal lymphadenopathy. Biopsies of the abdominal nodes revealed virtual obliteration...

journal_title：Archives of pathology & laboratory medicine

authors： Hancock JC,Prchal JT,Bennett JM,Listinsky CM

更新日期：1997-05-01 00:00:00

abstract：:Papillary fibroelastomas are rare and benign cardiac tumors that typically affect the cardiac valves. To the best of our knowledge, the English literature contains only 1 case report of pulmonary valve fibroelastoma diagnosed by echocardiogram and confirmed by surgical resection. There is a paucity of pathology litera...

journal_title：Archives of pathology & laboratory medicine

authors： Saad RS,Galvis CO,Bshara W,Liddicoat J,Dabbs DJ

更新日期：2001-07-01 00:00:00

abstract：CONTEXT:The results of studies among patients with antithrombin deficiency have suggested that the use of warfarin will increase the level of antithrombin. OBJECTIVE:To reevaluate the effect of warfarin on antithrombin levels using an automated amidolytic method in current use. DESIGN:Antithrombin levels were measure...

journal_title：Archives of pathology & laboratory medicine

authors： Sanfelippo MJ,Engel JM,Onitilo AA

更新日期：2014-07-01 00:00:00

abstract：CONTEXT:Implementation of proficiency testing for gynecologic cytology was delayed 20 years because of challenges addressing the subjective nature of cytologic interpretation and replicating normal working conditions. Concern remains regarding test scoring, slide validation, test environment, and other issues. How thes...

journal_title：Archives of pathology & laboratory medicine

authors： Howell LP,Nayar R,Savaloja L,Tabbara S,Thomas N,Winkler B,Tworek J

更新日期：2013-02-01 00:00:00

abstract：:Myocardial lesions were seen in dogs subjected to experimental hemorrhagic shock. In contrast, dogs that had been previously surgically treated by cardiac denervation and adrenalectomy, showed less myocardial damage. The latter group also had a substantially decreased myocardial I-norepinephrine content and a much low...

journal_title：Archives of pathology & laboratory medicine

authors： Hackel DB,Graham TC,Mikat EM

更新日期：1980-02-01 00:00:00

abstract：CONTEXT:The discovery that recurrent chromosomal translocations are involved in the pathogenesis of non-Hodgkin lymphomas has greatly improved our understanding of these diseases and revolutionized their diagnosis. OBJECTIVE:To review the mechanisms by which chromosomal translocations occur and contribute to the patho...

journal_title：Archives of pathology & laboratory medicine

authors： Vega F,Medeiros LJ

更新日期：2003-09-01 00:00:00

abstract：:A 50-year-old man presented with a lung mass in the left upper lobe, which was shown by electron microscopy to be a thymoma. There was no evidence of a mediastinal mass. The lymphocytes of the tumor reacted with monoclonal antibody T101, a pan T-cell marker, and with OKT8. B1 and B2 surface antigens characteristic of ...

journal_title：Archives of pathology & laboratory medicine

authors： Green WR,Pressoir R,Gumbs RV,Warner O,Naab T,Qayumi M

更新日期：1987-11-01 00:00:00

abstract：:Bowen disease is a variant of squamous cell carcinoma in situ. In some cases a pagetoid growth pattern can be observed with cytologically atypical clear cells arranged singly and in nests. The differential diagnosis of pagetoid Bowen disease includes primarily Paget disease and malignant melanoma in situ, as well as o...

journal_title：Archives of pathology & laboratory medicine

authors： Williamson JD,Colome MI,Sahin A,Ayala AG,Medeiros LJ

更新日期：2000-03-01 00:00:00

abstract：CONTEXT.—:Mutations within the same signature transduction pathway are redundant and, therefore, most are mutually exclusive. Laboratory errors, however, may introduce unexpected coexisting mutations. OBJECTIVE.—:To validate coexisting mutations within epidermal growth factor receptor (EGFR), mitogen-activated protein...

journal_title：Archives of pathology & laboratory medicine

authors： De Marchi F,Haley L,Fryer H,Ibrahim J,Beierl K,Zheng G,Gocke CD,Eshleman JR,Belchis D,Illei P,Lin MT

更新日期：2019-02-01 00:00:00

abstract：:Changes in bile canaliculi (BCs) after bile duct ligation (BDL) are heterogeneous throughout the liver lobule. Male Wistar rats were killed five hours, 20 hours, four days, or eight days after BDL, and BCs were counted according to their shape (1, normal; 2, elongated with microvilli; 3, dilated, devoid of microvilli;...

journal_title：Archives of pathology & laboratory medicine

authors： Vital A,Bioulac-Sage P,Iron A,Balabaud C

更新日期：1982-09-01 00:00:00