Itch and motivation to scratch: an investigation of the central and peripheral correlates of allergen- and histamine-induced itch in humans.

abstract：:The movement representation in the primary motor cortex (M1) of the cat develops between postnatal weeks 7-12. The somatosensory representation in motor cortex is present by the age that the motor map begins to develop. In this study we examined the role of neural activity in development and maintenance of the M1 move...

journal_title：Journal of neurophysiology

authors： Chakrabarty S,Martin JH

更新日期：2005-11-01 00:00:00

abstract：:The octopus cells of the posteroventral cochlear nucleus receive inputs from auditory-nerve fibers and form one of the major ascending auditory pathways. They respond to acoustic and electrical stimulation transiently and are believed to carry temporal information in the precise timing of their action potentials. The ...

journal_title：Journal of neurophysiology

authors： Cai Y,Walsh EJ,McGee J

更新日期：1997-08-01 00:00:00

abstract：:1. To analyze the selectivity and the sparseness of firing to visual stimuli of single neurons in the primate temporal cortical visual area, neuronal responses were measured to a set of 68 visual stimuli in macaques performing a visual fixation task. The population of neurons analyzed had responses that occurred prima...

journal_title：Journal of neurophysiology

authors： Rolls ET,Tovee MJ

更新日期：1995-02-01 00:00:00

abstract：:1. Cellular properties were studied before and after bath application of the dihydropyridine L-type calcium channel antagonist nimodipine in aging and young rabbit hippocampal CA1 pyramidal cells in vitro. Various concentrations of nimodipine, ranging from 10 nM to 10 microM, were tested to investigate age- and concen...

journal_title：Journal of neurophysiology

authors： Moyer JR Jr,Thompson LT,Black JP,Disterhoft JF

更新日期：1992-12-01 00:00:00

abstract：:1. We studied the effect of temporarily inhibiting neurons in the caudal fastigial nucleus in two rhesus macaques trained to make saccades to jumping targets. We placed injections of the gamma-aminobutyric acid (GABA) agonist muscimol unilaterally or bilaterally at sites in the caudal fastigial nucleus where we had re...

journal_title：Journal of neurophysiology

authors： Robinson FR,Straube A,Fuchs AF

更新日期：1993-11-01 00:00:00

abstract：:Modularity in the central nervous system (CNS), i.e., the brain capability to generate a wide repertoire of movements by combining a small number of building blocks ("modules"), is thought to underlie the control of movement. Numerous studies reported evidence for such a modular organization by identifying invariant m...

journal_title：Journal of neurophysiology

authors： Delis I,Panzeri S,Pozzo T,Berret B

更新日期：2014-02-01 00:00:00

abstract：:1. Synaptic interactions between identified neurons in the flight system of the locust were investigated by the use of standard intracellular recording and staining techniques. The intent was to determine the distribution and functional significance of delayed excitatory connections, which have been previously describ...

journal_title：Journal of neurophysiology

authors： Robertson RM

更新日期：1991-05-01 00:00:00

abstract：:Across the entire human body, postural tone might play its most critical role in the body's axis because the axis joins the four limbs and head into a single functioning unit during complex motor tasks as well as in static postures. Although postural tone is commonly viewed as low-level, tonic motor activity, we hypot...

journal_title：Journal of neurophysiology

authors： Gurfinkel V,Cacciatore TW,Cordo P,Horak F,Nutt J,Skoss R

更新日期：2006-11-01 00:00:00

abstract：:The locus coeruleus (LC) noradrenergic (NE) neuromodulatory system is critically involved in regulation of neural excitability via its diffuse ascending projections. Tonic NE release in the forebrain is essential for maintenance of vigilant states and increases the signal-to-noise ratio of cortical sensory responses. ...

journal_title：Journal of neurophysiology

authors： Neves RM,van Keulen S,Yang M,Logothetis NK,Eschenko O

更新日期：2018-03-01 00:00:00

abstract：:Sensory cortical neurons display substantial receptive field dynamics during and after persistent sensory drive. Because a cell's response properties are determined by the inputs it receives, receptive field dynamics are likely to involve changes in the relative efficacy of different inputs to the cell. To test this h...

journal_title：Journal of neurophysiology

authors： Kohn A,Metz C,Tommerdahl MA,Whitsel BL

更新日期：2002-12-01 00:00:00

abstract：:Understanding how whisker-based tactile information is represented in the nervous system requires quantification of sensory input and observation of neural activity during whisking and whisker touch. Chronic electrophysiological methods have long been available to study neural responses in awake and behaving animals; ...

journal_title：Journal of neurophysiology

authors： Voigts J,Sakmann B,Celikel T

更新日期：2008-07-01 00:00:00

abstract：:1. Whether complex (C) cells are the only truly texture-sensitive units in the cat's primary visual cortex remains controversial. In view of the strong physiological significance of having putatively only one class of cells sensitive to visual noise in the striate cortex, we reinvestigated this issue. Sensitivities of...

journal_title：Journal of neurophysiology

authors： Casanova C,Savard T,Nordmann JP,Molotchnikoff S,Minville K

更新日期：1995-09-01 00:00:00

abstract：:L-type calcium channels couple membrane depolarization in neurons to numerous processes including gene expression, synaptic efficacy, and cell survival. To establish the contribution of L-type calcium channels to various signaling cascades, investigators have relied on their unique pharmacological sensitivity to dihyd...

journal_title：Journal of neurophysiology

authors： Lipscombe D,Helton TD,Xu W

更新日期：2004-11-01 00:00:00

abstract：:Previous analysis of the firing of individual rat hippocampal place cells has shown that their firing rate increases when they enter a place field and that their phase of firing relative to the ongoing theta oscillation (7-12 Hz) varies systematically as the rat traverses the place field, a phenomenon termed the theta...

journal_title：Journal of neurophysiology

authors： Jensen O,Lisman JE

更新日期：2000-05-01 00:00:00

abstract：:1. A method for adapting a standard stereotaxic frame for use with neonatal rats as young as postnatal day 1 (PD 1) was devised, and single-unit extracellular recordings were obtained from neurons in the locus ceruleus (LC) in urethan-anesthetized rats during different stages in development from PD 1 to PD 34. 2. The ...

journal_title：Journal of neurophysiology

authors： Nakamura S,Kimura F,Sakaguchi T

更新日期：1987-09-01 00:00:00

abstract：:The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows that the β(2)-adrenergic receptor (β(2)AR) is linked to the AMPA-type glutamate receptor subunit GluA1 via stargazin and PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam ...

journal_title：Journal of neurophysiology

authors： Qian H,Matt L,Zhang M,Nguyen M,Patriarchi T,Koval OM,Anderson ME,He K,Lee HK,Hell JW

更新日期：2012-05-01 00:00:00

abstract：:The vestibular organs in the base of the skull provide important information about head orientation and motion in space. Previous studies have suggested that both angular velocity information from the semicircular canals and information about head orientation and translation from the otolith organs are centrally proce...

journal_title：Journal of neurophysiology

authors： Laurens J,Straumann D,Hess BJ

更新日期：2010-09-01 00:00:00

abstract：:The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between ...

journal_title：Journal of neurophysiology

authors： Stewart CE,Kanicki AC,Altschuler RA,King WM

更新日期：2018-02-01 00:00:00

abstract：:Cell-surface glutamate transporters are essential for the proper function of early cortical networks because their dysfunction induces seizures in the newborn rat in vivo. We have now analyzed the consequences of their inhibition by DL-TBOA on the activity of the developing CA1 rat hippocampal network in vitro. DL-TBO...

journal_title：Journal of neurophysiology

authors： Cattani AA,Bonfardin VD,Represa A,Ben-Ari Y,Aniksztejn L

更新日期：2007-10-01 00:00:00

abstract：:Membrane-permeable arachidonic acid (AA) is liberated in a Ca2+-dependent way inside cells. By using whole cell patch clamp we show that intracellular AA (1 pM) selectively reduces IA in rat hippocampal neurons, whereas extracellular application requires a 10(6)-fold concentration. The nonmetabolized AA analogue ETYA ...

journal_title：Journal of neurophysiology

authors： Bittner K,Müller W

更新日期：1999-07-01 00:00:00

abstract：:1. Single-unit recordings were made, under moderate gaseous anesthesia (33% O2-66% N2O + 0.5/0.6% halothane), in the ventrobasal (VB) thalamic complex of rats (n = 42) with a mononeuropathy created 2-3 wk beforehand, by four loose ligatures around the common sciatic nerve. Before the recording session, three behaviora...

journal_title：Journal of neurophysiology

authors： Guilbaud G,Benoist JM,Jazat F,Gautron M

更新日期：1990-11-01 00:00:00

abstract：:Current and voltage-clamp recordings were made at room temperature from cultured mouse spinal neurons using conventional two-electrode voltage-clamp techniques and electrodes filled with either 3 M KCl, 3 M CsCl, or 3 M Cs2SO4. In the presence of tetraethylammonium and tetrodotoxin, "fast" (rapidly rising and falling)...

journal_title：Journal of neurophysiology

authors： Owen DG,Segal M,Barker JL

更新日期：1986-06-01 00:00:00

abstract：:According to Alexander's law (AL), the slow phase velocity of nystagmus of vestibular origin is dependent on horizontal position, with lower velocity when gaze is directed in the slow compared with the fast phase direction. Adaptive changes in the velocity-to-position neural integrator are thought to cause AL. Althoug...

journal_title：Journal of neurophysiology

authors： Bockisch CJ,Hegemann S

更新日期：2008-12-01 00:00:00

abstract：:1. Two monkeys were trained to grasp an object between the thumb and index finger and lift it to a vertical distance of 12-25 mm. Up to 12 different conditions defined by different combinations of object weights (15, 65, and 115 g) and four surface textures (oiled metal, smooth metal, fine and coarse sandpaper) were u...

journal_title：Journal of neurophysiology

authors： Picard N,Smith AM

更新日期：1992-11-01 00:00:00

abstract：:To understand the contribution of the human presupplementary motor area (pre-SMA) in sequential motor behavior, we performed a series of finger key-press experiments. Experiment 1 revealed that each subject had a spontaneous tendency to organize or "chunk" a long sequence into shorter components. We hypothesized that ...

journal_title：Journal of neurophysiology

authors： Kennerley SW,Sakai K,Rushworth MF

更新日期：2004-02-01 00:00:00

abstract：:Motor cortex plays a substantial role in driving movement, yet the details underlying this control remain unresolved. We analyzed the extent to which movement-related information could be extracted from single-trial motor cortical activity recorded while monkeys performed center-out reaching. Using information theoret...

journal_title：Journal of neurophysiology

authors： Golub MD,Yu BM,Schwartz AB,Chase SM

更新日期：2014-07-15 00:00:00

abstract：:The granular layer of the cerebellum has a disproportionately large number of excitatory (granule cells) versus inhibitory neurons (Golgi cells). Its synaptic organization is also unique with a dense reciprocal innervation between granule and Golgi cells but without synaptic contacts among the neurons of either popula...

journal_title：Journal of neurophysiology

authors： Maex R,De Schutter E

更新日期：1998-11-01 00:00:00

abstract：:1. Reflex responses were elicited in muscles that act at the ankle by electrical stimulation of low-threshold afferents from the foot in human subjects who were reclining supine. During steady voluntary contractions, stimulus trains (5 pulses at 300 Hz) were delivered at two intensities to the sural nerve (1.2-4.0 tim...

journal_title：Journal of neurophysiology

authors： Aniss AM,Gandevia SC,Burke D

更新日期：1992-05-01 00:00:00

abstract：:Subjects were asked to track, with their eyes or their hand, the movement of a target that maintained a constant speed and made a single, abrupt change in direction. The tracking speed and direction of motion after the step change in target direction were compared for the eyes and the hand. After removal of the saccad...

journal_title：Journal of neurophysiology

authors： Engel KC,Anderson JH,Soechting JF

更新日期：2000-09-01 00:00:00

abstract：:Motor cortex (M1) activity between postnatal weeks 5 and 7 is essential for normal development of the corticospinal tract (CST) and visually guided movements. Unilateral reversible inactivation of M1, by intracortical muscimol infusion, during this period permanently impairs development of the normal dorsoventral dist...

journal_title：Journal of neurophysiology

authors： Chakrabarty S,Friel KM,Martin JH

更新日期：2009-03-01 00:00:00