The prevention of contrast induced nephropathy by sarpogrelate in patients with chronic kidney disease: a study protocol for a prospective randomized controlled clinical trial.

abstract：BACKGROUND:Exercise-based cardiac rehabilitation is a beneficial therapy for patients with chronic heart failure. The delivery of exercise-based cardiac rehabilitation should adopt an evidence-based approach, as well as be culturally appropriate and sensitive to individual needs and preferences. The Baduanjin Eight-Sil...

journal_title：Trials

authors： Chen X,Jiang W,Lin X,Lundborg CS,Wen Z,Lu W,Marrone G

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:It is widely agreed that triglyceride (TG)-lowering therapy is imperative in early hypertriglyceridemia-induced acute pancreatitis (HTG-AP). Intravenous insulin with or without heparin, and plasmapheresis are available regimens. However, there is no consensus on first-line therapy. METHODS/DESIGN:The Bi-TPA...

journal_title：Trials

authors： Song X,Shi D,Cui Q,Yu S,Yang J,Song P,Walline J,Xu J,Zhu H,Yu X

更新日期：2019-06-18 00:00:00

abstract：BACKGROUND:A high intake of salt is a major risk factor for cardiovascular diseases. Despite decades of effort to reduce salt consumption, the salt intake in China is still considerably above the recommended level. Thus, this study aims to design and implement an intelligent household added salt monitoring system (SALT...

journal_title：Trials

authors： Xian J,Zeng M,Zhu R,Cai Z,Shi Z,Abdullah AS,Zhao Y

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Home parenteral nutrition (HPN) is a life-preserving therapy for patients with chronic intestinal failure (CIF) indicated for patients who cannot achieve their nutritional requirements by enteral intake. Intravenously administered lipid emulsions (ILEs) are an essential component of HPN, providing energy and...

journal_title：Trials

authors： Klek S,Chambrier C,Cooper SC,Gabe S,Kunecki M,Pironi L,Rahman F,Sobocki J,Szczepanek K,Wanten G,Lincke N,Glotzbach B,Forbes A

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Osteoporosis-related fractures are a significant public health concern. Interventions that increase detection and treatment of osteoporosis, as well as prevention of fractures and falls, are substantially underutilized. This paper outlines the protocol for a pragmatic randomised trial of a multifaceted commu...

journal_title：Trials

authors： Ciaschini PM,Straus SE,Dolovich LR,Goeree RA,Leung KM,Woods CR,Zimmerman GM,Majumdar SR,Spadafora S,Fera LA,Lee HN

更新日期：2008-11-04 00:00:00

abstract：BACKGROUND:Childhood obesity is one of the most critical public health problems in the world. It is associated with low neuromuscular function and postural deformities. Whether weight loss can improve postural stability and neuromuscular control, benefit daily activities, or prevent injury is unknown. Therefore, this s...

journal_title：Trials

authors： Sun F,Wang LJ,Wang L

更新日期：2015-04-10 00:00:00

abstract：OBJECTIVES:Primary Objective: To determine the feasibility of delivering a protocolised, remote, online, Eye Movement Desensitisation and Reprocessing (EMDR) intervention, within 12-weeks of hospital discharge, for adult survivors of Covid-19 related critical illness. Secondary objectives: To investigate whether remote...

journal_title：Trials

authors： Bates A,Rushbrook S,Shapiro E,Grocott M,Cusack R

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:Suicide risk among individuals with schizophrenia (SZ) is intractably high, with over 40% of individuals attempting to take their own lives during their lifetime and an estimated 5-10% completing suicide. At present, available pharmacological and psychotherapeutic treatments offer limited risk reduction bene...

journal_title：Trials

authors： Beck-Felts K,Goodman M,Ospina LH,Wall M,McEvoy J,Jarskog LF,Ballon JS,Bartels MN,Buchsbaum R,Sloan RP,Stroup TS,Kimhy D

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Worldwide, prevalence rates of adolescent non-suicidal self-injury (NSSI) range between 13 and 45%. In Germany, lifetime prevalence of NSSI is around 25% in non-clinical samples, and the one-year prevalence for repetitive NSSI is 4%. NSSI is present in the context of several axis I and II disorders (for exam...

journal_title：Trials

authors： Fischer G,Brunner R,Parzer P,Resch F,Kaess M

更新日期：2013-09-13 00:00:00

abstract：BACKGROUND:Diabetes mellitus is associated with risk of sudden sensorineural hearing loss (SSNHL). Systemic and intratympanic corticosteroids are the two primary treatments for SSNHL in patients with diabetes mellitus. The benefit of intratympanic compared to systemic treatment is the reduced systemic steroid exposure ...

journal_title：Trials

authors： Yang W,Li X,Zhong J,Mei X,Liu H,Yang L,Lu L,Hu H

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:There is a large treatment gap with few community services for people with schizophrenia in low income countries largely due to the shortage of specialist mental healthcare human resources. Community based rehabilitation (CBR), involving lay health workers, has been shown to be feasible, acceptable and more ...

journal_title：Trials

authors： Chatterjee S,Leese M,Koschorke M,McCrone P,Naik S,John S,Dabholkar H,Goldsmith K,Balaji M,Varghese M,Thara R,Patel V,Thornicroft G,COmmunity care for People with Schizophrenia in India (COPSI) group.

更新日期：2011-01-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：Trials

authors： Sheridan R,Martin-Kerry J,Hudson J,Parker A,Bower P,Knapp P

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Disinvestment from inefficient or ineffective health services is a growing priority for health care systems. Provision of allied health services over the weekend is now commonplace despite a relative paucity of evidence supporting their provision. The relatively high cost of providing this service combined w...

journal_title：Trials

authors： Haines TP,O'Brien L,Mitchell D,Bowles KA,Haas R,Markham D,Plumb S,Chiu T,May K,Philip K,Lescai D,McDermott F,Sarkies M,Ghaly M,Shaw L,Juj G,Skinner EH

更新日期：2015-04-02 00:00:00

abstract：BACKGROUND:The ACTION study (Attention deficit hyperactivity disorder Controlled Trial Investigation Of a Non-stimulant) is a multi-center, double-blind, randomized cross-over trial of the non-stimulant medication, Atomoxetine, in children and adolescents with attention deficit hyperactivity disorder (ADHD). The primar...

journal_title：Trials

authors： Tsang TW,Kohn MR,Hermens DF,Clarke SD,Clark CR,Efron D,Cranswick N,Lamb C,Williams LM

更新日期：2011-03-13 00:00:00

abstract：BACKGROUND:Adolescence is a high-risk time for the development of mental health and substance use problems. However, fewer than one in four 16-24 year-olds with a current disorder access health services, with those experiencing a substance use disorder being the least likely to seek professional help. Research indicate...

journal_title：Trials

authors： Lubman DI,Berridge BJ,Blee F,Jorm AF,Wilson CJ,Allen NB,McKay-Brown L,Proimos J,Cheetham A,Wolfe R

更新日期：2016-08-08 00:00:00

abstract：:Following the South African case, Treatment Action Campaign and Others v Minister of Health and Others, the use of 'pilot' studies to investigate interventions already proven efficacious, offered free of charge to government, but confined by the government to a small part of the population, may violate children's righ...

journal_title：Trials

authors： Oduwo E,Edwards SJ

更新日期：2014-07-16 00:00:00

abstract：BACKGROUND:Less invasive surfactant administration (LISA) is a way of giving surfactant without endotracheal intubation and has shown to be promising in reducing the incidence of bronchopulmonary dysplasia (BPD) in preterm infants. However, the mechanism underlying its beneficial effect and variations in the technique ...

journal_title：Trials

authors： Zhu J,Bao Y,Du L,Huang H,Lv Q,Jiang Y,Dai Y,Chen Z,Shi J,Shi Y,Yang C,Mei H,Jiang H,Sun Y,Sun X

更新日期：2020-06-11 00:00:00

abstract：BACKGROUND:We describe the study design, procedures, and development of the risk counseling protocol used in a randomized controlled trial to evaluate the impact of genetic testing for diabetes mellitus (DM) on psychological, health behavior, and clinical outcomes. METHODS/DESIGN:Eligible patients are aged 21 to 65 ye...

journal_title：Trials

authors： Voils CI,Coffman CJ,Edelman D,Maciejewski ML,Grubber JM,Sadeghpour A,Cho A,McKenzie J,Blanpain F,Scheuner M,Sandelowski M,Gallagher MP,Ginsburg GS,Yancy WS Jr

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Angulated fractures of the distal forearm are very frequent lesions in childhood. Currently, there are no standard guidelines on whether these children should be treated conservatively with a cast; with reduction and a cast; or with reduction, pinning and a cast under anesthesia. Minor prospective and retros...

journal_title：Trials

authors： Adrian M,Wachtlin D,Kronfeld K,Sommerfeldt D,Wessel LM

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:Obesity represents a major public health problem and is the fifth leading risk factor for mortality. Morbid obesity is associated with chronic systemic inflammation which increases the risk of comorbidities. Bariatric surgery (BS) is considered an effective intervention for obese patients. However, BS is ass...

journal_title：Trials

authors： Delgado André L,Basso-Vanelli RP,Di Thommazo-Luporini L,Angélica Ricci P,Cabiddu R,Pilon Jürgensen S,Ricardo de Oliveira C,Arena R,Borghi-Silva A

更新日期：2018-10-31 00:00:00

abstract：BACKGROUND:With a survival rate of 6 to 11%, out-of-hospital cardiac arrest (OHCA) remains a healthcare challenge with room for improvement in morbidity and mortality. The guidelines emphasize the highest possible quality of cardiopulmonary resuscitation (CPR) and chest compressions (CC). It is essential to minimize CC...

journal_title：Trials

authors： Buléon C,Parienti JJ,Morilland-Lecoq E,Halbout L,Cesaréo E,Dubien PY,Jardel B,Boyer C,Husson K,Andriamirado F,Benet X,Morel-Marechal E,Aubrion A,Muntean C,Dupire E,Roupie E,Hubert H,Vilhelm C,Gueugniaud PY,CILICA-HS

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:Multiple pregnancies are one of the major safety concerns of in vitro fertilization (IVF) due to the increased risk of maternal and neonatal complications. Single embryo transfer is the most effective way to reduce the risk of multiple pregnancies. Selection of the embryo and optimization of the implantation...

journal_title：Trials

authors： Wei D,Sun Y,Liu J,Liang X,Zhu Y,Shi Y,Chen ZJ

更新日期：2017-06-05 00:00:00

abstract：BACKGROUND:Older adults living in nursing homes spend the majority of their time inactive. The associated levels of chronic disease place an increasing burden on healthcare systems. Physical activity (PA) interventions delivered through exercise classes may be resource-intensive and require specialist staff. The aim of...

journal_title：Trials

authors： Barrett E,Gillespie P,Newell J,Casey D

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) has been identified as a major contributor to the development of cardiovascular disease (CVD). Current recommendations for dietary management of people with MetS involve quantitative and qualitative modifications of food intake, such as high consumption of vegetables, fruits, and wh...

journal_title：Trials

authors： Ramprasath VR,Thandapilly SJ,Yang S,Abraham A,Jones PJ,Ames N

更新日期：2015-10-31 00:00:00

abstract：BACKGROUND:Obesity affects 25% of the UK adult population but modest weight loss can reduce the incidence of obesity-related chronic disease. Some effective weight loss treatments exist but there is no nationally available National Health Service (NHS) treatment service, and general practitioners (GPs) rarely discuss w...

journal_title：Trials

authors： Lewis A,Jolly K,Adab P,Daley A,Farley A,Jebb S,Lycett D,Clarke S,Christian A,Jin J,Thompson B,Aveyard P

更新日期：2013-11-19 00:00:00

abstract：BACKGROUND:Understanding why people take part in health research is critical to improve research efficiency and generalisability. The aim of this overview of systematic reviews was to identify psychosocial determinants of research participation and map them to psychological theory and empirical recruitment research, to...

journal_title：Trials

authors： Sheridan R,Martin-Kerry J,Hudson J,Parker A,Bower P,Knapp P

更新日期：2020-03-12 00:00:00

abstract：BACKGROUND:Colonoscopy is one of the most effective methods of cancer prevention and detection, particularly for individuals with familial risk. Recruitment of family members to behavioral intervention trials remains uniquely challenging, owing to the intensive process required to identify and contact them. Recruiting ...

journal_title：Trials

authors： Simmons RG,Lee YC,Stroup AM,Edwards SL,Rogers A,Johnson C,Wiggins CL,Hill DA,Cress RD,Lowery J,Walters ST,Jasperson K,Higginbotham JC,Williams MS,Burt RW,Schwartz MD,Kinney AY

更新日期：2013-04-30 00:00:00

abstract：BACKGROUND:The purpose of clinical trials of acupuncture is to help clinicians and patients make decisions about treatment. Yet this is not straightforward: some trials report acupuncture to be superior to sham (placebo) acupuncture while others show evidence that acupuncture is superior to usual care but not sham, and...

journal_title：Trials

authors： Vickers AJ,Cronin AM,Maschino AC,Lewith G,Macpherson H,Victor N,Sherman KJ,Witt C,Linde K,Acupuncture Trialists' Collaboration.

更新日期：2010-09-28 00:00:00

abstract：BACKGROUND:Verrucae are a common, infectious and sometimes painful problem. The optimal treatment for verrucae is unclear due to a lack of high quality randomised controlled trials. The primary objective of this study is to compare the clinical effectiveness of two common treatments for verrucae: cryotherapy using liqu...

journal_title：Trials

authors： Cockayne ES,EVERT Trial Team.

更新日期：2010-02-08 00:00:00

abstract：OBJECTIVES:To assess the effect of prone positioning therapy on intubation rate in awake patients with COVID-19 and acute respiratory failure. TRIAL DESIGN:This is a two-center parallel group, superiority, randomized (1:1 allocation ratio) controlled trial. PARTICIPANTS:All patients admitted to the Hospital Civil de ...

journal_title：Trials

authors： Ibarra-Estrada MÁ,Marín-Rosales M,García-Salcido R,Aguirre-Díaz SA,Vargas-Obieta A,Chávez-Peña Q,López-Pulgarín JA,Mijangos-Méndez JC,Aguirre-Avalos G

更新日期：2020-11-23 00:00:00