Evaluation of IgG antibody response against Rickettsia conorii and Rickettsia slovaca in patients with DEBONEL/TIBOLA.

Abstract:

:The aim of the study was to determine the IgG antibody response to spotted fever group Rickettsia (SFGR) R. conorii and R. slovaca, and its specificity and sensitivity in patients with DEBONEL/TIBOLA. A prospective study of 31 patients with DEBONEL was carried out from January 2001 to May 2004. The SFGR serology testing (IgG IFA) for the diagnosis of DEBONEL/TIBOLA showed 61% sensitivity and 100% specificity. The R. slovaca antigen allowed the diagnoses in 18 of the 31 patients (58%), and 17 patients (55%) were diagnosed with this disease using R. conorii antigen. Therefore, using R. slovaca as antigen did not improve the sensitivity of the assay.

journal_name

Ann N Y Acad Sci

authors

Santibáñez S,Ibarra V,Portillo A,Blanco JR,Martínez de Artola V,Guerrero A,Oteo JA

doi

10.1196/annals.1374.113

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

570-2

eissn

0077-8923

issn

1749-6632

pii

1078/1/570

journal_volume

1078

pub_type

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