Abstract：
:The interaction of monovalent cations and membrane phospholipids has a great theoretical and practical importance. Because of the very low differences between the binding forces of monovalent cations to phospholipids, the methods applied up till now did not succeed in completely elucidating this interaction. We developed a new thin-layer chromatographic method to study the interaction of monovalent cations and phospholipids. Silica gel layers were impregnated with a solution of the phospholipid to be investigated (phosphatidylserine or phosphatidylcholine) to produce a multibilayer surface with the polar groups on the outside. 22Na+, 42K+, 86Rb+, 137Cs+ salts were then applied at the origin and chromatographed in a solvent system presaturated with the phospholipid. Our results indicate that phosphatidylcholine and phosphatidylserine bind the monovalent ions with smaller hydrated ion radii more strongly. The binding forces decrease in the order C2+ greater than Rb+ greater than K+ greater than Na+ for both phospholipids. The binding forces are greater for phosphatidylserine than for phosphatidylcholine. The differences between the binding forces of monovalent cations to phosphatidylcholine are greater than to phosphatidylserine indicating that phosphatidylcholine differentiates relatively better between the monovalent cations than phosphatidylserine.
journal_name
Chem Phys Lipidsjournal_title
Chemistry and physics of lipidsauthors
Cserháti T,Szögyi Mdoi
10.1016/0009-3084(83)90062-2subject
Has Abstractpub_date
1983-12-01 00:00:00pages
93-9issue
1eissn
0009-3084issn
1873-2941pii
0009-3084(83)90062-2journal_volume
34pub_type
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更新日期：1994-04-19 00:00:00
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更新日期：1996-12-20 00:00:00
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更新日期：1999-04-01 00:00:00
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journal_title：Chemistry and physics of lipids
pub_type： 杂志文章
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更新日期：2004-01-01 00:00:00
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更新日期：1986-12-31 00:00:00
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更新日期：1988-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：1989-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/0009-3084(77)90013-5
更新日期：1977-04-01 00:00:00
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更新日期：2018-07-01 00:00:00
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journal_title：Chemistry and physics of lipids
pub_type： 杂志文章,评审
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更新日期：1987-07-01 00:00:00
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journal_title：Chemistry and physics of lipids
pub_type： 杂志文章
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更新日期：1986-06-01 00:00:00
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journal_title：Chemistry and physics of lipids
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journal_title：Chemistry and physics of lipids
pub_type： 杂志文章
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journal_title：Chemistry and physics of lipids
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journal_title：Chemistry and physics of lipids
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更新日期：2011-02-01 00:00:00
