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Properties of unusual phospholipids: I. Synthesis, monolayer investigations and calorimetry of diacylglycerophosphocholines containing monoacetylenic acyl chains.

Abstract：

:Isomeric diacylglycerophosphocholines containing various octadecynoic acids (4-, 6-, 9-, 12-, 14- and 17-octadecynoic acid) were synthesized and purified to homogeneity. Their behaviour in monolayers, when studied by the Langmuir-Blodgett film balance technique, revealed systematic relationships between structure and packing properties. The thermotropic phase behaviour of these novel phospholipids, as measured by differential scanning calorimetry, depended in a systematic fashion on the position of the triple bond: the gel-to-liquid-crystalline phase transition temperature (Tm) passed through a minimum of -3.4 degrees C for a triple bond in position 9.

journal_name

Chem Phys Lipids

journal_title

Chemistry and physics of lipids

authors

Rürup J,Mannova M,Brezesinski G,Schmid RD

doi

10.1016/0009-3084(94)90086-8

subject

Has Abstract

pub_date

1994-04-19 00:00:00

pages

187-98

issue

2

eissn

0009-3084

issn

1873-2941

pii

0009-3084(94)90086-8

journal_volume

70

pub_type

杂志文章

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