Wall motion abnormalities and electrocardiographic changes in acute transmural myocardial infarction: implications of reciprocal ST segment depression.

Abstract:

:Left ventricular ejection fraction and regional wall motion were assessed by multigated equilibrium radionuclide ventriculography within 24 hours of onset of first acute transmural myocardial infarction (MI) in 32 patients. Abnormal left ventricular wall motion was noted in all 16 patients with anterior infarction and in 14 of 16 (87.5%) patients with inferior infarction. Regional wall motion abnormalities frequently included areas adjacent to and remote from those predicted by the ECG location of ST elevation and pathologic Q waves. Such remote wall motion abnormalities were associated with reciprocal ST segment depression in 17 of 18 (94%) patients, and conversely reciprocal ST segment depressions were associated with remote wall motion abnormalities in 17 of 24 (71%) patients. The left ventricular ejection fraction was lower in patients with a reciprocal ST segment depression compared to those without (anterior MI 0.29 +/- 0.07 vs 0.43 +/- 0.08, p less than 0.01; inferior MI 0.45 +/- 0.11 vs 0.63 +/- 0.06, p less than 0.001). In addition, the peak MB-CK levels were higher in patients with compared to those without reciprocal ST segment depression (anterior MI 268 +/- 183 vs 102 +/- 60, p less than 0.05; inferior MI 186 +/- 120 vs 67 +/- 20, p less than 0.05). Thirteen of 18 (72%) patients with reciprocal ST segment depression compared to 4 of 13 (31%) patients without reciprocal ST segment depression had a complicated clinical course during their hospital stay. These observation suggest that global left ventricular dysfunction in first acute transmural MI is greater when reciprocal ST segment depression is present on the 12-lead ECG.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Am Heart J

journal_title

American heart journal

authors

Pichler M,Shah PK,Peter T,Singh B,Berman D,Shellock F,Swan HJ

doi

10.1016/0002-8703(83)90644-0

subject

Has Abstract

pub_date

1983-11-01 00:00:00

pages

1003-9

issue

5 Pt 1

eissn

0002-8703

issn

1097-6744

pii

0002-8703(83)90644-0

journal_volume

106

pub_type

杂志文章
  • Influence of gravity on pulmonary venous flow velocity patterns: analysis of left and right pulmonary venous flow velocities in left and right decubitus positions.

    abstract:BACKGROUND:The pulmonary venous flow signal measured by transesophageal echocardiography is generally recorded from the left upper pulmonary vein in the left lateral decubitus position, whereas that by transthoracic echocardiography is from the right upper pulmonary vein in the left semi-lateral decubitus position. The...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(99)70486-2

    authors: Izumi C,Iga K,Himura Y,Gen H,Konishi T

    更新日期:1999-03-01 00:00:00

  • Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention.

    abstract:BACKGROUND:Peak creatine kinase (CK)-MB concentration is related to reperfusion success and clinical outcomes after fibrinolytic therapy for acute myocardial infarction. However, prognostic implications of CK-MB measurements after primary percutaneous coronary intervention (PCI), which provides more predictable and con...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2014.06.008

    authors: Bagai A,Schulte PJ,Granger CB,Mahaffey KW,Christenson RH,Bell G,Lopes RD,Green CL,Lincoff AM,Armstrong PW,Roe MT

    更新日期:2014-10-01 00:00:00

  • Long-term outcome after heart transplantation for peripartum cardiomyopathy.

    abstract::To elucidate the long-term outcome and frequency of complications after heart transplantation for peripartum cardiomyopathy (PPCM), we compared the courses of eight consecutive patients undergoing transplantation for PPCM with those of nine female age-matched control subjects undergoing transplantation for idiopathic ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(94)90051-5

    authors: Rickenbacher PR,Rizeq MN,Hunt SA,Billingham ME,Fowler MB

    更新日期:1994-05-01 00:00:00

  • Response of the left ventricle in idiopathic dilated cardiomyopathy to postextrasystolic potentiation.

    abstract::The effectiveness of postextrasystolic potentiation (PESP) was assessed to detect residual function of the left ventricle in seven patients with idiopathic dilated cardiomyopathy (IDC). The postextrasystolic changes in the aortic pressure pulse, global left ventricular function, and quantitative regional left ventricu...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90661-2

    authors: Yamazoe M

    更新日期:1987-06-01 00:00:00

  • Vorapaxar in patients with peripheral artery disease and acute coronary syndrome: insights from Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER).

    abstract:BACKGROUND:In the TRACER trial, vorapaxar, a protease-activated receptor-1 antagonist, plus standard care in non-ST-segment elevation acute coronary syndrome (NSTE ACS) patients did not significantly reduce the primary composite end point but reduced a key secondary end point and significantly increased bleeding. Histo...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2014.06.017

    authors: Jones WS,Tricoci P,Huang Z,Moliterno DJ,Harrington RA,Sinnaeve PR,Strony J,Van de Werf F,White HD,Held C,Armstrong PW,Aylward PE,Chen E,Patel MR,Mahaffey KW

    更新日期:2014-10-01 00:00:00

  • Phase image analysis of anomalous ventricular activation in pediatric patients with preexcitation syndromes or ventricular tachycardia.

    abstract::This prospective study evaluated the accuracy of phase analysis of scintigraphic imaging in defining the site of earliest ventricular activation in pediatric patients with electrophysiologic disorders. Twenty patients (10.8 +/- 5.5 years) with preexcitation (n = 16) or ventricular tachycardia (VT) (n = 4) were indepen...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(93)90015-2

    authors: Silka MJ,Chelsky R,Kron J,Wilson RA

    更新日期:1993-02-01 00:00:00

  • Fasting glucose levels within the high normal range predict cardiovascular outcome.

    abstract:BACKGROUND:Diabetes mellitus and impaired glucose metabolism are associated with increased risk for cardiovascular disease (CVD). However, it is still not clear whether glucose levels can predict CVD risk among patients without diabetes. The primary aim of this study is to assess whether normoglycemic fasting plasma gl...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2012.03.023

    authors: Shaye K,Amir T,Shlomo S,Yechezkel S

    更新日期:2012-07-01 00:00:00

  • Percutaneous transluminal coronary angioplasty of the left coronary artery in patients with chronic occlusion of the right coronary artery: clinical and functional results.

    abstract::The safety and therapeutic benefits of percutaneous transluminal coronary angioplasty of the left anterior descending coronary artery, the left circumflex coronary artery or both were assessed in 61 patients with chronic (greater than 3 months) occlusion of the right coronary artery. Recanalization of the right corona...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)90994-s

    authors: De Bruyne B,Renkin J,Col J,Wijns W

    更新日期:1991-08-01 00:00:00

  • A comparison of the acute hypotensive effects of two different doses of nifedipine.

    abstract::To determine whether a dose of 5 mg of nifedipine would be useful in the treatment of hypertensive emergencies, we compared the acute hypotensive effects of two different doses of nifedipine, 5 mg and 10 mg, in patients with severe hypertension. In this prospective, randomized, double-blind study, 30 consecutive black...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-8703(92)90283-2

    authors: Maharaj B,van der Byl K

    更新日期:1992-09-01 00:00:00

  • Presyncopal sympathetic withdrawal is the same in patients with vasodepressor syncope and controls who faint on head-up tilting.

    abstract::Head-up tilt provokes vasodepressor syncope in patients with this disorder but may also cause fainting in unaffected subjects. The aims of this study were to examine autonomic function and sequential changes in heart rate variability and plasma catecholamines during graded head-up tilt in patients with vasodepressor s...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(97)70213-8

    authors: Prinz-Zaiss M,Yeap AN,Moguilevski V,Trigg L,McGrath BP

    更新日期:1997-02-01 00:00:00

  • Impact of do-not-resuscitation orders on quality of care performance measures in patients hospitalized with acute heart failure.

    abstract:BACKGROUND:Heart failure (HF) is one of the leading causes of morbidity and mortality among Americans. Despite increased interest in end-of-life care, the implications of do-not-resuscitate (DNR) orders in acutely ill patients with HF remain unclear. The goals of this observational study were to describe the use of DNR...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2008.01.030

    authors: Chen JL,Sosnov J,Lessard D,Goldberg RJ

    更新日期:2008-07-01 00:00:00

  • Long-term lorcainide therapy in patients with ventricular tachycardia.

    abstract::One hundred patients inducible at electrophysiologic studies underwent serial drug testing with procainamide, lidocaine, and lorcainide to determine comparative efficacy. Acute intravenous administration was followed by repeat programmed electrical stimulation (PES) studies on separate days for each antiarrhythmic dru...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-8703(85)90412-0

    authors: Somberg J,Butler B,Flowers D,Keefe D,Torres V,Miura D

    更新日期:1985-01-01 00:00:00

  • Comparative hemodynamic effects of dopamine and dobutamine in patients with acute cardiogenic circulatory collapse.

    abstract::The hemodynamic effects of dopamine (DPM) and dobutamine (DBM) were compared in 13 patients with acute cardiogenic circulatory collapse. All patients presented with acute pump failure and inadequate systemic perfusion, and most were hypotensive. Nine patients had an acute myocardial infarction (AMI); the other four pa...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-8703(82)90562-2

    authors: Francis GS,Sharma B,Hodges M

    更新日期:1982-06-01 00:00:00

  • Ischemic ST segment depression in leads V2-V3 as the presenting electrocardiographic feature of posterolateral wall myocardial infarction.

    abstract::In this study of 14 patients hospitalized with a first event of myocardial infarction, maximal ST segment depression in precordial leads V2 and V3 was the sole ECG finding during chest pain in the first 24 hours of evolving posterolateral infarction, based upon further two-dimensional echocardiographic examination and...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90916-1

    authors: Sclarovsky S,Topaz O,Rechavia E,Strasberg B,Agmon J

    更新日期:1987-05-01 00:00:00

  • Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial.

    abstract:BACKGROUND:Clinical outcomes and the effects of oral anticoagulants among patients with acute coronary syndrome (ACS) and either a history of or acute heart failure (HF) are largely unknown. We aimed to assess the relationship between prior HF or acute HF complicating an index ACS event and subsequent clinical outcomes...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2014.12.022

    authors: Cornel JH,Lopes RD,James S,Stevens SR,Neely ML,Liaw D,Miller J,Mohan P,Amerena J,Raev D,Huo Y,Urina-Triana M,Gallegos Cazorla A,Vinereanu D,Fridrich V,Harrington RA,Wallentin L,Alexander JH,APPRAISE-2 Study Group.

    更新日期:2015-04-01 00:00:00

  • Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial.

    abstract:BACKGROUND:Device-detected subclinical atrial fibrillation (AF) refers to infrequent, short-lasting, asymptomatic AF that is detected only with long-term continuous monitoring. Subclinical AF is common and associated with an increased risk of stroke; however, the risk of stroke with subclinical AF is lower than for cli...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2017.04.008

    authors: Lopes RD,Alings M,Connolly SJ,Beresh H,Granger CB,Mazuecos JB,Boriani G,Nielsen JC,Conen D,Hohnloser SH,Mairesse GH,Mabo P,Camm AJ,Healey JS

    更新日期:2017-07-01 00:00:00

  • Cardiac and vascular effects of fingolimod: mechanistic basis and clinical implications.

    abstract::Fingolimod, a sphingosine-1-phosphate receptor (S1PR) modulator, was the first oral disease-modifying therapy approved for relapsing forms of multiple sclerosis; it reduces autoreactive lymphocytes' egress from lymphoid tissues by down-regulating S1PRs. Sphingosine-1-phosphate signaling is implicated in a range of phy...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2014.06.028

    authors: Camm J,Hla T,Bakshi R,Brinkmann V

    更新日期:2014-11-01 00:00:00

  • Evaluation of pericardial effusion with computed tomography.

    abstract::Evaluation of pericardial effusion was attempted with computed tomography in 11 patients. The volume and distribution of pericardial fluid were assessed with satisfactory resolution and the nature of the fluid was estimated by the difference in x-ray transparency (CT numbers). The volume of pericardial fluid calculate...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(80)90618-3

    authors: Tomoda H,Hoshiai M,Furuya H,Oeda Y,Matsumoto S,Tanabe T,Tamachi H,Sasamoto H,Koide S,Kuribayashi S,Matsuyama S

    更新日期:1980-06-01 00:00:00

  • Comparison of the hemodynamic responses to molsidomine and isosorbide dinitrate in congestive heart failure.

    abstract::To evaluate the mechanisms involved in nitrate tolerance, we randomized 23 patients with congestive heart failure resulting from coronary artery disease to an isosorbide dinitrate or a molsidomine infusion. The drugs were titrated to decrease pulmonary capillary wedge pressure by > or = 30% or > or = 10 mm Hg. Then is...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-8703(94)90632-7

    authors: Unger P,Vachiery JL,de Cannière D,Staroukine M,Berkenboom G

    更新日期:1994-09-01 00:00:00

  • Factors for modifying the termination of resuscitation rule in out-of-hospital cardiac arrest.

    abstract:BACKGROUND:False positive rate (FPR) of the current basic life support (BLS) termination of resuscitation (TOR) rule in out-of-hospital cardiac arrest (OHCA) patients (not witnessed; no return of spontaneous circulation prior to transport; and no shocks were delivered) has been ethically challenging. We validated the c...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2019.04.003

    authors: Yoon JC,Kim YJ,Ahn S,Jin YH,Lee SW,Song KJ,Shin SD,Hwang SO,Kim WY,Korean Cardiac Arrest Research Consortium KoCARC.

    更新日期:2019-07-01 00:00:00

  • Short-term outcomes after percutaneous coronary intervention: effects of stenting and institutional volume shifts.

    abstract:BACKGROUND:This study examines how the dissemination of stenting and procedural shifts to high-volume facilities have affected short-term outcomes after percutaneous coronary intervention (PCI). METHODS:Discharge information from the 1994 and 1997 US Nationwide Inpatient Sample was used. Data from 1994 involved 84,036...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:

    authors: Watanabe CT,Maynard C,Ritchie JL

    更新日期:2002-08-01 00:00:00

  • Comparison of transradial and femoral approaches for percutaneous coronary interventions: a systematic review and hierarchical Bayesian meta-analysis.

    abstract:BACKGROUND:Despite lower risks of access site-related complications with transradial approach (TRA), its clinical benefit for percutaneous coronary intervention (PCI) is uncertain. We conducted a systematic review and meta-analysis of clinical studies comparing TRA and transfemoral approach (TFA) for PCI. METHODS:Rand...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ahj.2012.01.015

    authors: Bertrand OF,Bélisle P,Joyal D,Costerousse O,Rao SV,Jolly SS,Meerkin D,Joseph L

    更新日期:2012-04-01 00:00:00

  • Apixaban compared with parenteral heparin and/or vitamin K antagonist in patients with nonvalvular atrial fibrillation undergoing cardioversion: Rationale and design of the EMANATE trial.

    abstract:BACKGROUND:Stroke prevention in anticoagulation-naïve patients with atrial fibrillation undergoing cardioversion has not been systematically studied. OBJECTIVE:To determine outcomes in anticoagulation-naïve patients (defined as those receiving an anticoagulant for <48 hours during the index episode of atrial fibrillat...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2016.06.008

    authors: Ezekowitz MD,Pollack CV,Sanders P,Halperin JL,Spahr J,Cater N,Petkun W,Breazna A,Kirchhof P,Oldgren J

    更新日期:2016-09-01 00:00:00

  • Myocardial hibernation in the infarcted region cannot be assessed from the presence of stress-induced ischemia: usefulness of delayed image of exercise thallium-201 scintigraphy.

    abstract::To examine the relationship between the improvement of wall motion in infarcted regions after percutaneous transluminal coronary angioplasty (PTCA) and thallium-201 uptake in the delayed image of exercise thallium-201 scintigraphy before PTCA, 14 patients with anterior old myocardial infarction were studied. Exercise ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(93)90053-c

    authors: Yamamoto K,Asada S,Masuyama T,Nanto S,Matsumura Y,Naito J,Hirayama A,Mishima M,Naka M,Sasaki J

    更新日期:1993-01-01 00:00:00

  • Evaluation of a nine-lead Holter monitor for identifying and localizing ischemia and coronary artery disease detected by quantitative thallium-201 tomography.

    abstract::We devised a nine-lead Holter monitor system with a lead-switching technique to record electrocardiograms from multiple sites in the anterior and the posterior or lateral chest. Leads CM1 to CM6, high lateral (HL), low lateral (LL), and low posterior chest (LB) were used. The sensitivity, specificity, and predictive a...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-8703(94)90595-9

    authors: Tanabe T,Yoshioka K,Ide M,Kanemoto N,Suzuki Y

    更新日期:1994-11-01 00:00:00

  • Body surface isopotential maps in old anterior myocardial infarction undetectable by 12-lead electrocardiograms.

    abstract::Body surface isopotential maps were recorded in 30 normal subjects and 32 patients with clinical evidence of old anterior myocardial infarction but without ECG findings of infarction. Position of the minimum in maps was compared at 5 msec intervals from the onset of QRS between the normal and infarction groups. A sign...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90463-0

    authors: Hirai M,Ohta T,Kinoshita A,Toyama J,Nagaya T,Yamada K

    更新日期:1984-10-01 00:00:00

  • Blood pressure control and hormone replacement therapy in postmenopausal women at risk for coronary heart disease.

    abstract:BACKGROUND:Coronary heart disease (CHD) in women is strongly associated with estrogen deprivation. For example, risk for CHD increases dramatically after menopause. However, the role of hormone replacement therapy (HRT) in CHD prevention currently is unresolved. To better understand CHD in women, the precise mechanisms...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2002.121262

    authors: McCubbin JA,Helfer SG,Switzer FS 3rd,Price TM

    更新日期:2002-04-01 00:00:00

  • Percutaneous coronary mid-infra-red laser angioplasty.

    abstract::A pilot study was performed to determine the safety and efficacy of coronary pulsed mid-infra-red laser angioplasty. The laser was coupled with a novel 2.0 mm multifiber catheter consisting of 37 optical fibers of 150 microns each arranged concentrically around a 0.018-inch central lumen and a soft leading tapered dis...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)91015-f

    authors: Geschwind HJ,Dubois-Rande JL,Zelinsky R,Morelle JF,Boussignac G

    更新日期:1991-08-01 00:00:00

  • Neurosurgical evacuation of intracranial hemorrhage after thrombolytic therapy for acute myocardial infarction: experience from the GUSTO-I trial. Global Utilization of Streptokinase and tissue-plasminogen activator (tPA) for Occluded Coronary Arteries.

    abstract:BACKGROUND:Intracranial hemorrhage is an uncommon but very dangerous complication in patients receiving thrombolytic therapy for acute myocardial infarction. Neurosurgical evacuation is often an available treatment option. However, the association between neurosurgical evacuation and clinical outcomes in these patients...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-8703(99)70152-3

    authors: Mahaffey KW,Granger CB,Sloan MA,Green CL,Gore JM,Weaver WD,White HD,Simoons ML,Barbash GI,Topol EJ,Califf RM

    更新日期:1999-09-01 00:00:00

  • Pulmonary artery hypertension in severe aortic stenosis: incidence and mechanism.

    abstract::We investigated the incidence and mechanism of pulmonary artery hypertension (PAH) in a consecutive series of patients with aortic stenosis who were undergoing diagnostic cardiac catheterization. Forty-five patients with severe aortic stenosis were divided into two groups: group 1 comprised 13 patients (29%) with PAH ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(93)90067-j

    authors: Silver K,Aurigemma G,Krendel S,Barry N,Ockene I,Alpert J

    更新日期:1993-01-01 00:00:00